Cited by 2,852Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and TreatmentsCardiac pacing and defibrillation studies

The DOI matches its Crossref record; 33 of the 34 references it cites were found in a registry or an index.

Updated Worldwide Survey on the Methods, Efficacy, and Safety of Catheter Ablation for Human Atrial Fibrillation

Cappato, Riccardo, Calkins, Hugh, Chen, Shih-Ann, Davies, Wyn, Iesaka, Yoshito, Kalman, Jonathan, Kim, You-Ho, Klein, George, Natale, Andrea, Packer, Douglas, Skanes, Allan, Ambrogi, Federico, Biganzoli, Elia·2010·Circulation Arrhythmia and Electrophysiology

DOI 10.1161/circep.109.859116

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Abstract

BACKGROUND: The purpose of this study was to provide an updated worldwide report on the methods, efficacy, and safety of catheter ablation of atrial fibrillation (AF). METHODS AND RESULTS: A questionnaire with 46 questions was sent to 521 centers from 24 countries in 4 continents. Complete interviews were collected from 182 centers, of which 85 reported to have performed 20,825 catheter ablation procedures on 16,309 patients with AF between 2003 and 2006. The median number of procedures per center was 245 (range, 2 to 2715). All centers included paroxysmal AF, 85.9% also included persistent and 47.1% also included long-lasting AF. Carto-guided left atrial circumferential ablation (48.2% of patients) and Lasso-guided ostial electric disconnection (27.4%) were the most commonly used techniques. Efficacy data were analyzed with centers representing the unit of analysis. Of 16,309 patients with full disclosure of outcome data, 10 488 (median, 70.0%; interquartile range, 57.7% to 75.4%) became asymptomatic without antiarrhythmic drugs and another 2047 (10.0%; 0.5% to 17.1%) became asymptomatic in the presence of previously ineffective antiarrhythmic drugs over 18 (range, 3 to 24) months of follow-up. Success rates free of antiarrhythmic drugs and overall success rates were significantly larger in 9590 patients with paroxysmal AF (74.9% and 83.2%) than in 2800 patients with persistent AF (64.8% and 75.0%) and 1108 patients with long-lasting AF (63.1% and 72.3%) (P<0.0001). Major complications were reported in 741 patients (4.5%). CONCLUSIONS: When analyzed in a large number of electrophysiology laboratories worldwide, catheter ablation of AF shows to be effective in approximately 80% of patients after 1.3 procedures per patient, with approximately 70% of them not requiring further antiarrhythmic drugs during intermediate follow-up.

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Background
Use of Dabigatran for Periprocedural Anticoagulation in Patients Undergoing Catheter Ablation for Atrial Fibrillation
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“bleeding complications, however, represent rare but serious consequences.(3) Sheaths and catheters in the left atrium (LA),”
Background
Radiofrequency ablation of atrial fibrillation under therapeutic international normalized ratio: A safe and efficacious periprocedural anticoagulation strategy
Hussein, A. A., Martin, D. O., Saliba, W. I., Patel, D., Karim, S., Batal, O., Banna, M., Williams‐Andrews, M., Sherman, M., Kanj, M. H., et al. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.07.007 · Cited by 164
Severe Pulmonary Vein Stenosis Resulting From Ablation for Atrial Fibrillation
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“Number of prior atrial fibrillation ablations 1 (1, 2) 1 (1, 2) 1 (1, 2) 1 (1, 2) 1.”
Predictors of Atrial Fibrillation Recurrence after Catheter Ablation: Data from the German Ablation Registry
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Atrioesophageal Fistula
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“Study characteristics deemed eligible for inclusion were the following: (1) patient underwent surgical or percutaneous ablation for AF, (2) documented development of AEF after procedure, and (3) published in English language.”
Effect of Sleep Apnea and Continuous Positive Airway Pressure on Cardiac Structure and Recurrence of Atrial Fibrillation
Neilan, T. G., Farhad, H., Dodson, J. A., Shah, R. V., Abbasi, S. A., Bakker, J. P., Michaud, G. F., van der Geest, R., Blankstein, R., Steigner, M., et al. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.113.000421 · Cited by 158
“006 LV mass index, g/m(2) 71 (12) 75 (14) 70 (12) 0.”
Catheter Ablation for Atrial Fibrillation
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Incidence of oesophageal wall injury post-pulmonary vein antrum isolation for treatment of patients with atrial fibrillation
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Long-Term Outcomes After Cryoballoon Pulmonary Vein Isolation
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“Ablation procedures for circumferential pulmonary vein isolation (PVI) by encircling the pulmonary vein (PV) antrum have become the therapy of choice for drugrefractory symptomatic focal atrial fibrillation (AF) (1), with a continual increase in the number of procedures performed annually (2).”
Background
Automated analysis of atrial late gadolinium enhancement imaging that correlates with endocardial voltage and clinical outcomes: A 2-center study
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“LGE CMR and procedural outcome Persistent AF and increased atrial size are the only current predictors of reduced procedural success from AF ablation in the literature.(1,22) In our PAF population with relatively normal LA size, preexisting atrial scarring detected by LGE CMR identified patients who were more likely t…”
Background
Pulmonary Vein Antral Isolation for Paroxysmal Atrial Fibrillation: Results from Long-Term Follow-Up
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Outcomes of Medicare Beneficiaries Undergoing Catheter Ablation for Atrial Fibrillation
Piccini, J. P., Sinner, M. F., Greiner, M. A., Hammill, B. G., Fontes, J. D., Daubert, J. P., Ellinor, P. T., Hernandez, A. F., Walkey, A. J., Heckbert, S. R., et al. (2012) · Circulation · doi:10.1161/circulationaha.112.109330 · Cited by 150
Cost-Effectiveness of Radiofrequency Catheter Ablation Compared With Antiarrhythmic Drug Therapy for Paroxysmal Atrial Fibrillation
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Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 1
Diener, H., Aisenberg, J., Ansell, J., Atar, D., BREITHARDT, G. E., Eikelboom, J. W., Ezekowitz, M. D., Granger, C. B., Halperin, J. L., Hohnloser, S. H., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehv643 · Cited by 147
“Thromboembolic events are among the most serious procedurerelated complications, with an incidence between 1 and 5%.(24) – 28 Silent brain lesions detected by magnetic resonance imaging are common after AF ablation (10–15% of patients),(29) but their clinical relevance and implications for long-term cognitive decline…”
Background
Rhythm control in atrial fibrillation
Piccini, J. P., & Fauchier, L. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31277-6 · Cited by 147
Catheter Ablation of Atrial Fibrillation: An Overview for Clinicians
Mujović, N. M., Marinković, M. M., Lenarczyk, R., Tilz, R. R., & Potpara, T. (2017) · Advances in Therapy · doi:10.1007/s12325-017-0590-z · Cited by 147
“for the procedure, and this technology has the longest post-ablation follow-up data [2, 3, 6, 22].”
BackgroundMethod
Stroke and thromboembolism prevention in atrial fibrillation
Jamé, S., & Barnes, G. D. (2019) · Heart · doi:10.1136/heartjnl-2019-314898 · Cited by 147
Efficacy of Catheter Ablation for Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis of Evidence From Randomized and Nonrandomized Controlled Trials
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Feasibility, Safety, and Efficacy of Posterior Wall Isolation During Atrial Fibrillation Ablation
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Dabigatran vs warfarin for radiofrequency catheter ablation of atrial fibrillation
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Histopathologic Characterization of Chronic Radiofrequency Ablation Lesions for Pulmonary Vein Isolation
Kowalski, M., Grimes, M. M., Perez, F. J., Kenigsberg, D. N., Koneru, J. N., Kasirajan, V., Wood, M. A., & Ellenbogen, K. A. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.09.076 · Cited by 143
“The success rate at 12 months for patients at experienced centers is approximately 70%, with wide variability in reported successful outcomes (2).”
Background
Incidence of complications related to catheter ablation of atrial fibrillation and atrial flutter: a nationwide in-hospital analysis of administrative data for Germany in 2014
Steinbeck, G., Sinner, M. F., Lutz, M., Müller‐Nurasyid, M., Kääb, S., & Reinecke, H. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy452 · Cited by 143
“5%.(4,10) Yet, the incidence of vascular complications alone may vary markedly(23) with female sex, age >75 years, and presence of hypertensive heart disease being associated with a higher risk for complications.”
Background
A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference
Kirchhof, P. F., BREITHARDT, G. E., Bax, J. J., Benninger, G., Blomström‐Lundqvist, C., Boriani, G., Brandes, A., Brown, H., Brueckmann, M., Calkins, H. G., et al. (2015) · EP Europace · doi:10.1093/europace/euv304 · Cited by 143
“Hybrid therapy, defined as the use of antiarrhythmic drug therapy more than 3 months following an ablation to reduce symptoms and/or episodes of AF, is a common therapeutic concept in AF patients.(101,102,103) While it is common practice to stop antiarrhythmic drugs a few weeks or months after Table 6 Quality indicato…”
Background
Pulmonary Vein Total Occlusion Following Catheter Ablation for Atrial Fibrillation
Biase, L. D., Fahmy, T. S. E., Wazni, O. M., Bai, R., Patel, D., Lakkireddy, D., Cummings, J. E., Schweikert, R. A., Burkhardt, J. D., Elayi, C. S., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.08.038 · Cited by 140
Efficacy of Antiarrhythmic Drugs Short-Term Use After Catheter Ablation for Atrial Fibrillation (EAST-AF) trial
Kaitani, K., Inoue, K., Kobori, A., Nakazawa, Y., Ozawa, T., Kurotobi, T., Morishima, I., Miura, F., Watanabe, T., Masuda, M., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv501 · Cited by 140
Efficacy, Safety, and Outcomes of Catheter Ablation of Atrial Fibrillation in Patients With Heart Failure With Preserved Ejection Fraction
Machino‐Ohtsuka, T., Seo, Y., Ishizu, T., Sugano, A., Atsumi, A., Yamamoto, M., Kawamura, R., Machino, T., Kuroki, K., Yamasaki, H., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.07.020 · Cited by 139
One year follow-up after cryoballoon isolation of the pulmonary veins in patients with paroxysmal atrial fibrillation
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Renal Artery Stenosis After Renal Sympathetic Denervation
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2016 Guidelines of the Taiwan Heart Rhythm Society and the Taiwan Society of Cardiology for the management of atrial fibrillation
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Cognitive dysfunction in atrial fibrillation
Madhavan, M., Graff‐Radford, J., Piccini, J. P., & Gersh, B. J. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0075-z · Cited by 146
Approach to the Catheter Ablation Technique of Paroxysmal and Persistent Atrial Fibrillation: A Meta-Analysis of the Randomized Controlled Trials
Parkash, R., Tang, A., Sapp, J. L., & Wells, G. A. (2011) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2011.02010.x · Cited by 137
The impact of image integration on catheter ablation of atrial fibrillation using electroanatomic mapping: a prospective randomized study
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Risk of Mortality Following Catheter Ablation of Atrial Fibrillation
Cheng, E. P., Liu, C. F., Yeo, I., Markowitz, S. M., Thomas, G., Ip, J. E., Kim, L. K., Lerman, B. B., & Cheung, J. W. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.08.1036 · Cited by 137
Comparison of Stent Versus Balloon Angioplasty for Pulmonary Vein Stenosis Complicating Pulmonary Vein Isolation
Prieto, L. R., Schoenhagen, P., Arruda, M., Natale, A., & Worley, S. E. (2008) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2008.01110.x · Cited by 135
Image integration increases efficacy of paroxysmal atrial fibrillation catheter ablation: results from the CartoMergeTM Italian Registry
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Comparison of Cryoballoon and Radiofrequency Ablation of Pulmonary Veins in 40 Patients with Paroxysmal Atrial Fibrillation: A Case‐Control Study
Linhart, M., Bellmann, B., Mittmann-Braun, E. L., SCHRICKEL, J. W., BITZEN, A., Andrié, R., Yang, A., Nickenig, G., Lickfett, L., & Lewalter, T. (2009) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2009.01560.x · Cited by 134
Impact of left atrial fibrosis and left atrial size on the outcome of catheter ablation for atrial fibrillation
den Uijl, D. W., Delgado, V., Bertini, M., Tops, L. F., Trines, S. A. I. P., de Veire, N. R. V., Zeppenfeld, K., Schalij, M. J., & Bax, J. J. (2011) · Heart · doi:10.1136/hrt.2010.215335 · Cited by 133
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Mechanistic Inquiry into the Role of Tissue Remodeling in Fibrotic Lesions in Human Atrial Fibrillation
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“However, overall success rates for terminating AF via catheter ablation are low, with recent surveys reporting only 70% success (3).”
Background
Catheter ablation for atrial fibrillation in hypertrophic cardiomyopathy: a systematic review and meta-analysis
Providencia, R., Elliott, P., Patel, K., McCready, J., Babu, G., Srinivasan, N., Bronis, K., Papageorgiou, N., Chow, A., Rowland, E., et al. (2016) · Heart · doi:10.1136/heartjnl-2016-309406 · Cited by 122
Does periprocedural anticoagulation management of atrial fibrillation affect the prevalence of silent thromboembolic lesion detected by diffusion cerebral magnetic resonance imaging in patients undergoing radiofrequency atrial fibrillation ablation with open irrigated catheters? Results from a prospective multicenter study
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Computed Tomography‐Fluoroscopy Image Integration‐Guided Catheter Ablation of Atrial Fibrillation
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Effects of Sex on the Incidence of Cardiac Tamponade After Catheter Ablation of Atrial Fibrillation
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“This may explain the lower rate of tamponade documented in our study as compared with that observed in the Medicare survey(18) and previous reports.(2,6,7) Figure 3.”
Result
Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2008) : Digest Version
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Progression From Esophageal Thermal Asymptomatic Lesion to Perforation Complicating Atrial Fibrillation Ablation
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Prevalence and Predictors of Complications of Radiofrequency Catheter Ablation for Atrial Fibrillation
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A Systematic Review of Randomized Trials Comparing Radiofrequency Ablation with Antiarrhythmic Medications in Patients with Atrial Fibrillation
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Authors: Cappato, R., Calkins, H., Chen, S.-A., Davies, W., Iesaka, Y., Kalman, J., Kim, Y.-H., Klein, G., Natale, A., Packer, D., Skanes, A., Ambrogi, F., & Biganzoli, E.
Affiliations: The Royal Melbourne Hospital (AU)
ORCID: Cappato, Riccardo
Calkins, Hugh
Chen, Shih-Ann
Kalman, Jonathan
Kim, You-Ho
Klein, George
Natale, Andrea
Packer, Douglas
Skanes, Allan
Ambrogi, Federico
Biganzoli, Elia
Venue: Circulation Arrhythmia and Electrophysiology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2010-02
Volume: 3
Issue: 1
Pages: 32-38
ISSN: 1941-3084 (ISSN-L)
1941-3149
DOI: 10.1161/circep.109.859116
OpenAlex: W2146673314
Cited by: 2,852
References: 34
Citations by year: 2026: 26 · 2025: 42 · 2024: 51 · 2023: 68 · 2022: 81 · 2021: 110 · 2020: 126 · 2019: 125 · 2018: 141 · 2017: 177 · 2016: 199 · 2015: 184 · 2014: 220 · 2013: 246 · 2012: 218
FWCI: 156.54
Type: journal article
Language: en
Open access: closed
Locations: Circulation Arrhythmia and Electrophysiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords: catheter ablation, atrial fibrillation, paroxysmal atrial fibrillation, persistent atrial fibrillation, ablation efficacy, ablation safety, procedural complications, CARTO system
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Anticoagulants, Atrial Fibrillation, Data Collection, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Treatment Outcome, Catheter Ablation, Young Adult

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Updated Worldwide Survey on the Methods, Efficacy, and Safety of Catheter Ablation for Human Atrial Fibrillation

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