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Updated Worldwide Survey on the Methods, Efficacy, and Safety of Catheter Ablation for Human Atrial Fibrillation
Abstract
BACKGROUND: The purpose of this study was to provide an updated worldwide report on the methods, efficacy, and safety of catheter ablation of atrial fibrillation (AF). METHODS AND RESULTS: A questionnaire with 46 questions was sent to 521 centers from 24 countries in 4 continents. Complete interviews were collected from 182 centers, of which 85 reported to have performed 20,825 catheter ablation procedures on 16,309 patients with AF between 2003 and 2006. The median number of procedures per center was 245 (range, 2 to 2715). All centers included paroxysmal AF, 85.9% also included persistent and 47.1% also included long-lasting AF. Carto-guided left atrial circumferential ablation (48.2% of patients) and Lasso-guided ostial electric disconnection (27.4%) were the most commonly used techniques. Efficacy data were analyzed with centers representing the unit of analysis. Of 16,309 patients with full disclosure of outcome data, 10 488 (median, 70.0%; interquartile range, 57.7% to 75.4%) became asymptomatic without antiarrhythmic drugs and another 2047 (10.0%; 0.5% to 17.1%) became asymptomatic in the presence of previously ineffective antiarrhythmic drugs over 18 (range, 3 to 24) months of follow-up. Success rates free of antiarrhythmic drugs and overall success rates were significantly larger in 9590 patients with paroxysmal AF (74.9% and 83.2%) than in 2800 patients with persistent AF (64.8% and 75.0%) and 1108 patients with long-lasting AF (63.1% and 72.3%) (P<0.0001). Major complications were reported in 741 patients (4.5%). CONCLUSIONS: When analyzed in a large number of electrophysiology laboratories worldwide, catheter ablation of AF shows to be effective in approximately 80% of patients after 1.3 procedures per patient, with approximately 70% of them not requiring further antiarrhythmic drugs during intermediate follow-up.
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“In patients who experience symptomatic recurrences of AF despite antiarrhythmic drug therapy, all RCTs showed better sinus rhythm maintenance with catheter ablation than on antiarrhythmic drugs.586,713,727,728”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [727]
In the citing paper
“Five to seven per cent of patients will suffer severe complications after catheter ablation of AF, and 2-3% will experience life-threatening but usually manageable complications.727,[748][749][750]”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [727]
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Long-term single procedure efficacy of catheter ablation of atrial fibrillation
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“The second worldwide multicentre survey on catheter ablations performed from 2003–2006, showed that the success rate had increased to 70% with a 30% risk of recurrent AF, over a mean follow-up period of 18 months.(7) These findings are very similar to the data reported in our study with a 45% risk of recurrent AF foun…”
SCHMIDT, M., DORWARTH, U., ANDRESEN, D., BRACHMANN, J., KUCK, K., KUNISS, M., LEWALTER, T., SPITZER, S., WILLEMS, S., SENGES, J., et al. (2014) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.12267 · Cited by 126
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Virtual Electrophysiological Study of Atrial Fibrillation in Fibrotic Remodeling
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“However, only a 70% success rate in achieving freedom from AF has been reported with this approach[5].”
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Lead Extraction Is Preferred for Lead Revisions and System Upgrades: When Less Is More
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HotBalloon Ablation of the Pulmonary Veins for Paroxysmal AF
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Catheter ablation of atrial fibrillation: an update
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Deja vu in the theories of atrial fibrillation dynamics
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Efficacy of circumferential pulmonary vein ablation of atrial fibrillation in endurance athletes
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Clinical Outcome of Catheter Ablation in Patients With Nonparoxysmal Atrial Fibrillation
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“As techniques and technologies have improved, catheter ablation of AF has became a standard and effective therapy for patients with symptomatic and drug-refractory AF, and its popularity continues to escalate.(5) Recently, 2 centers reported the long-term results of catheter ablation in AF and demonstrated that the ar…”
BackgroundTreatment of Atrial Fibrillation
Prystowsky, E. N., Padanilam, B. J., & Fogel, R. I. (2015) · JAMA · doi:10.1001/jama.2015.7505 · Cited by 117
Herrera‐Siklody, C., Arentz, T., Minners, J., Jesel, L., Stratz, C., Valina, C. M., Weber, R., Kalusche, D., Toti, F., Morel, O., et al. (2011) · Heart Rhythm · doi:10.1016/j.hrthm.2011.09.017 · Cited by 117
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A Highly Articulated Robotic Surgical System for Minimally Invasive Surgery
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A decade of catheter ablation of cardiac arrhythmias in Sweden: ablation practices and outcomes
Holmqvist, F., Kesek, M., Englund, A., Blomström‐Lundqvist, C., Karlsson, L. O., Kennebäck, G., Poçi, D., Samo-Ayou, R., Sigurjonsdottir, R. B., Ringborn, M., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy709 · Cited by 113
“However, the reported risk of an adverse event in an AF ablation was 2.8%, which is substantially lower than that reported in the most recent worldwide survey on catheter ablation for AF.12 The rate of death following AF ablation in this study is considerably lower than in the worldwide survey.”
InfluentialAldhoon, B., Wichterle, D., Peichl, P., Cihak, R. J., & Kautzner, J. (2012) · EP Europace · doi:10.1093/europace/eus304 · Cited by 112
“However, it is considered a complex procedure with many steps that is associated with higher incidence of complications in comparison with conventional CA procedures.(1) It has been demonstrated that complication rates at high-volume centres are lower than at centres performing fewer procedures.”
BackgroundMotoki, H., Negishi, K., Kusunose, K., Popović, Z., Bhargava, M., Wazni, O. M., Saliba, W. I., Chung, M. K., Marwick, T. H., & Klein, A. L. (2014) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2014.08.017 · Cited by 111
Kirchhof, P. F., Bax, J. J., Blomstrom-Lundquist, C., Calkins, H., Camm, A. J., Cappato, R., Cosío, F. G., Crijns, H. J. G. M., Diener, H., Goette, A., et al. (2009) · EP Europace · doi:10.1093/europace/eup124 · Cited by 112
Mondesert, B. A., Andrade, J. G., Khairy, P., Guerra, P. G., Shohoudi, A., Dyrda, K., Macle, L., Rivard, L., Thibault, B., Talajic, M. R., et al. (2014) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.113.001238 · Cited by 110
“by continuous abdominal palpation during phrenic nerve pacing.(2,4,5,14) Within this context, our series of electromyographic monitoring has demonstrated the following: (1) diaphrag-”
BackgroundKornej, J., Hindricks, G., Kosiuk, J., Arya, A., Sommer, P., Husser, D., Rolf, S., Richter, S., Huo, Y., Piorkowski, C., et al. (2014) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.113.001182 · Cited by 110
“As techniques and technologies have improved, catheter ablation has became an effective treatment strategy for patients with drug-refractory AF, with continuous escalation of its popularity.(2) Of note, recent ESC guidelines suggest including catheter ablation even as a first-line therapy for specific groups of AF pat…”
BackgroundPanikker, S., Jarman, J. W. E., Virmani, R., Kutys, R., Haldar, S., Lim, E., Butcher, C., Khan, H. R., Mantziari, L., Nicol, E. D., et al. (2016) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.115.003710 · Cited by 110
Furlanello, F., Lupo, P., Pittalis, M., FORESTI, S., Serdoz, L. V., Francia, P., Ambroggi, G. D., Ferrero, P., Nardi, S., Inama, G., et al. (2008) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2007.01077.x · Cited by 112
Wilton, S. B., Fundytus, A. M., Ghali, W. A., Veenhuyzen, G. D., Quinn, F. R., Mitchell, L. B., Hill, M. D., Faris, P., & Exner, D. V. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2010.06.053 · Cited by 109
Saad, E., d’Ávila, A., Costa, I. P., Aryana, A., Slater, C., Costa, R. E., Inácio, L. A. O., Maldonado, P., Neto, D. G. D. M., Camiletti, A. S., et al. (2011) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.111.963231 · Cited by 109
Martinek, M., Sigmund, E., Lemeš, C., Derndorfer, M., Aichinger, J., Winter, S., Jauker, W., Gschwendtner, M., Nesser, H., & Pürerfellner, H. (2012) · EP Europace · doi:10.1093/europace/eus329 · Cited by 108
“7%), the evidence of silent embolism is worrisome in a population already at high risk for cerebral embolism and dementia.(2,3) Considering that post-procedural MRI lesions are in any case a sign of brain damage—even if asymptomatic or not detected in follow-up MRI—and that a significant amount of patients will need a…”
BackgroundMicroembolism and Catheter Ablation I
Haines, D. E., Stewart, M. T., Ahlberg, S. E., Barka, N., Condie, C., Fiedler, G. R., Kirchhof, N., Halimi, F., & Deneke, T. (2013) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.111.973453 · Cited by 107
Kapa, S., Epstein, A. E., Callans, D. J., Garcia, F. C., Lin, D., Bala, R., Riley, M. P., Hutchinson, M. D., Gerstenfeld, E. P., Tzou, W. S., et al. (2013) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.12141 · Cited by 107
“Secondary study endpoints comprised “actionable events” that were defined as recordings made by ILR and not CM that resulted in change of clinical care and these included (1) initiation and/or withdrawal of antiarrhythmic drugs or atrioventricular nodal (AVN) blocking agents, (2) cardioversion, (3) discontinuation or…”
MethodResultEfficacy, Safety, and Outcome of Atrial Fibrillation Ablation in Septuagenarians
CORRADO, A., Patel, D., Riedlbauchová, L., Fahmy, T. S. E., Themistoclakis, S., Bonso, A., Rossillo, A., Hao, S. C., Schweikert, R. A., Cummings, J. E., et al. (2008) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2008.01124.x · Cited by 107
Atrial fibrillation and atrial flutter in athletes
Calvo, N., Brugada, J., Sitges, M., & Mont, L. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091171 · Cited by 110
“Pulmonary vein ablation Circumferential pulmonary vein ablation (CPVA) has been introduced in clinical practice as an effective and safe treatment of AF, especially in patients with paroxysmal AF and no structural heart disease.(55) Recent data support the efficacy of ablation strategy in athletes.”
BackgroundRadiofrequency Ablation of Atrial Fibrillation
Pratola, C., BALDO, E., Notarstefano, P., Toselli, T., & Ferrari, R. (2007) · Circulation · doi:10.1161/circulationaha.106.678789 · Cited by 106
“... connection, electrical stimulation at an amplitude of 10 mA and a duration of 2 ms was performed inside the circumferential line of ablation.4 At the end of the procedure, an adjunctive RF ablation line was created in the right atrium along the cavotricuspid isthmus with electrophysiological assessment of transist…”
InfluentialMirza, M., Caracciolo, G., Khan, U., Mori, N., Saha, S. K., Srivathsan, K. S., Altemose, G. T., Scott, L. R., Sengupta, P. P., & Jahangir, A. (2011) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-011-9560-6 · Cited by 107
“A readily available, inexpensive, and noninvasive method of assessing atrial substrate abnormality that provides prognostic information about the success of CA procedure is highly desirable [5].”
InfluentialNault, I., Miyazaki, S., Forclaz, A., Wright, M. J., Jadidi, A., Jaı̈s, P., Hocini, M., & Haı̈ssaguerre, M. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq079 · Cited by 106
Mechanical Esophageal Displacement During Catheter Ablation for Atrial Fibrillation
Koruth, J. S., Reddy, V. Y., Miller, M. A., Patel, K., Coffey, J. O., Fischer, A., Gomes, J. A., Dukkipati, S. R., d’Ávila, A., & Mittnacht, A. J. C. (2011) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2011.02162.x · Cited by 105
“A common approach to avoid damage is luminal esophageal temperature (LET) monitoring; however, (1) temperature rises mandate interruptions in energy delivery that interrupt workflow and potentially decrease procedural efficacy, and (2) esophageal fistulas have been reported even with LET monitoring.”
BackgroundCryoballoon versus Radiofrequency Catheter Ablation in Atrial Fibrillation: A Meta‐Analysis
Cardoso, R. N., Mendirichaga, R., Fernandes, G. C., HEALY, C., Lambrakos, L. K., Viles-González, J. F., Goldberger, J. J., & Mitrani, R. D. (2016) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.13047 · Cited by 106
“The main findings from the pooled population analysis were as follows: (1) there was no significant difference between groups with regards to the primary efficacy outcome of freedom from AT in a followup 12 months; (2) postprocedural PNP was significantly more common in the CB group, although the overwhelming majority…”
MethodResultScharf, C., Boersma, L. V. A., Davies, W. D., Kanagaratnam, P., Peters, N. S., Paul, V., Rowland, E., Grace, A. A., Fynn, S. P., Dang, L., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.07.009 · Cited by 105
Hammerstingl, C., SCHWEKENDIEK, M., Momčilović, D., Schueler, R., Sinning, J., SCHRICKEL, J. W., Mittmann-Braun, E. L., Nickenig, G., & Lickfett, L. (2011) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2011.02177.x · Cited by 105
The role of myocardial wall thickness in atrial arrhythmogenesis
Whitaker, J., Rajani, R., Chubb, H., Gabrawi, M., Varela, M., Wright, M. J., Niederer, S., & O'Neill, M. D. (2016) · EP Europace · doi:10.1093/europace/euw014 · Cited by 104
High-Power Radiofrequency Catheter Ablation of Atrial Fibrillation
Baher, A. A., Kheirkhahan, M., Rechenmacher, S. J., Marashly, Q., Kholmovski, E. G., Siebermair, J., Acharya, M. M., Aljuaid, M., Morris, A. K., Kaur, G., et al. (2018) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2018.07.017 · Cited by 103
“Although RFCA is generally considered safe, it still has inherent risks (2).”
BackgroundHALL, B. W., Jeevanantham, V., Simon, R. A., Filippone, J. D., Vorobiof, G., & Daubert, J. P. (2007) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-006-9052-2 · Cited by 104
Cost-Effectiveness of Radiofrequency Catheter Ablation for Atrial Fibrillation
Chan, P. S., Vijan, S. S., Morady, F., & Oral, H. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.01.070 · Cited by 104
A New Era in the Surgical Treatment of Atrial Fibrillation
Melby, S. J., Zierer, A. F., Bailey, M. S., Cox, J. L., Lawton, J. S., Munfakh, N. A., Crabtree, T. D., Moazami, N., Huddleston, C. B., Moon, M. R., et al. (2006) · Transactions of the Meeting of the American Surgical Association · doi:10.1097/01.sla.0000237654.00841.26 · Cited by 104
Wann, L. S., Curtis, A. B., January, C. T., Ellenbogen, K. A., Lowe, J. E., Estes, N. A. M., Page, R. L., Ezekowitz, M. D., Slotwiner, D. J., Jackman, W. M., et al. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.11.047 · Cited by 103
Incidence of Pulmonary Vein Stenosis After Radiofrequency Catheter Ablation of Atrial Fibrillation
Teunissen, C., Velthuis, B. K., Hassink, R. J., van der Heijden, J. F., Vonken, E.-J. P. A., Clappers, N., Doevendans, P. A., & Loh, P. K. K. (2017) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2017.02.003 · Cited by 104
Selective Molecular Potassium Channel Blockade Prevents Atrial Fibrillation
Amit, G., Kikuchi, K., Greener, I. D., Yang, L., Novack, V., & Donahue, J. K. (2010) · Circulation · doi:10.1161/circulationaha.109.911156 · Cited by 102
Andrade, J. G., Khairy, P., & Dubuc, M. (2013) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.112.973651 · Cited by 104
“excursion is detected by continuous abdominal palpation during phrenic nerve pacing.(62) Although alternative monitoring”
BackgroundLee, G., SPARKS, P. B., Morton, J. B., Kistler, P. M., Vohra, J. K., MEDI, C., Rosso, R., Teh, A. W., Halloran, K., & Kalman, J. M. (2010) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2010.01870.x · Cited by 101
Efficacy of radiofrequency catheter ablation in athletes with atrial fibrillation
Koopman, P., Nuyens, D., Garweg, C., La Gerche, A., De Buck, S., Van Casteren, L., Alzand, B., Willems, R., & Heidbuchel, H. (2011) · Europace · doi:10.1093/europace/eur142 · Cited by 102
Mechanisms and Drug Development in Atrial Fibrillation
Calvo, D., Rama, D. F., & Jalife, J. (2018) · Pharmacological Reviews · doi:10.1124/pr.117.014183 · Cited by 99
“However, success rates for persistent AF ablation remain far lower than paroxysmal AF and there is large variation in the strategies used worldwide, (Cappato et al., 2005; Calkins et al., 2007;Matsuo et al., 2007)which highlights the need and offers new opportunities for the development of a new…”
BackgroundNielsen, J. C., Lin, Y., Figueiredo, M. J. D. O., Shamloo, A. S., Alfie, A., Bovéda, S., Dagres, N., Toro, D. D., Eckhardt, L. L., Ellenbogen, K. A., et al. (2020) · Journal of Arrhythmia · doi:10.1002/joa3.12338 · Cited by 106
Ellis, E. R., Culler, S. D., Simon, A. W., & Reynolds, M. R. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.06.009 · Cited by 100
den Uijl, D. W., Gawrysiak, M., Tops, L. F., Trines, S. A. I. P., Zeppenfeld, K., Schalij, M. J., Bax, J. J., & Delgado, V. (2011) · EP Europace · doi:10.1093/europace/eur186 · Cited by 100
Verma, A., Macle, L., Cox, J. L., & Skanes, A. C. (2011) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2010.11.011 · Cited by 99
Mathematical Approaches to Understanding and Imaging Atrial Fibrillation
Trayanova, N. A. (2014) · Circulation Research · doi:10.1161/circresaha.114.302240 · Cited by 97
“quency ablation eliminates paroxysmal AF in 70% to 80% of the treated patient population.(81) Persistent AF is thought to”
BackgroundAytemir, K., Canpolat, U., Yorgun, H., Evranos, B., Kaya, E. B., ŞAHINER, L., & Özer, N. (2015) · EP Europace · doi:10.1093/europace/euv375 · Cited by 99
Calkins, H. G., Hindricks, G., Cappato, R., Kim, Y., Saad, E., Aguinaga, L., Akar, J. G., Badhwar, V., Brugada, J., Camm, A. J., et al. (2017) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-017-0277-z · Cited by 100
Hæusler, K. G., Koch, L., Herm, J., Kopp, U. A., Heuschmann, P. U., Endres, M., Schultheiss, H.-P., Schirdewan, A., & Fiebach, J. B. (2012) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2012.02420.x · Cited by 98
“These concerns are compounded as many patients undergo several ablation procedures before maintaining stable SR (6).”
BackgroundUpdate on atrial fibrillation: Part II
Savelieva, I., & Camm, A. J. (2008) · Clinical Cardiology · doi:10.1002/clc.20136 · Cited by 99
Aytemir, K., Gürses, K. M., Yalçın, M. U., Koçyiğit, D., Dural, M., Evranos, B., Yorgun, H., Ateş, A. H., ŞAHINER, L., Kaya, E. B., et al. (2014) · EP Europace · doi:10.1093/europace/euu273 · Cited by 98
Lim, T. W., Koay, C. H., See, V. A., McCall, R., CHIK, W. W. B., Zecchin, R. P., Byth, K., Seow, S., Thomas, L., Ross, D. L., et al. (2012) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.111.970293 · Cited by 99
“MIL ablation has been proposed as a means to improve outcomes of ostial or wide antral pulmonary vein isolation for AF.7,8 However, it can be difficult to achieve electric block across linear ablations in all patients.”
BackgroundInfluentialNielsen, J. C., Lin, Y.-J., de Oliveira Figueiredo, M. J., Sepehri Shamloo, A., Alfie, A., Boveda, S., Dagres, N., Di Toro, D., Eckhardt, L. L., Ellenbogen, K., et al. (2020) · EP Europace · doi:10.1093/europace/euaa065 · Cited by 98
Dixit, S., Gerstenfeld, E. P., Ratcliffe, S. J., Cooper, J. M., Russo, A. M., Kimmel, S. E., Callans, D. J., Lin, D., Verdino, R. J., Patel, V. V., et al. (2007) · Heart Rhythm · doi:10.1016/j.hrthm.2007.09.024 · Cited by 99
Feasibility of Electroporation for the Creation of Pulmonary Vein Ostial Lesions
Wittkampf, F. H. M., van Driel, V. J., van Wessel, H., Vink, A., Hof, I. E., Gründeman, P. F., Hauer, R. N. W., & Loh, P. K. K. (2010) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2010.01863.x · Cited by 97
Ligament of Marshall: Why it is important for atrial fibrillation ablation
Hwang, C., & Chen, P. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.08.034 · Cited by 97
Calkins, H. G., Brugada, J., Packer, D. L., Cappato, R., Chen, S.-A., Crijns, H. J. G. M., Damiano, R. J., Davies, D. W., Haines, D. E., Haı̈ssaguerre, M., et al. (2008) · EP Europace · doi:10.1093/europace/eun341 · Cited by 96
Delayed Cardiac Tamponade After Radiofrequency Catheter Ablation of Atrial Fibrillation
Cappato, R., Calkins, H., Chen, S.-A., Davies, W., Iesaka, Y., Kalman, J., Kim, Y.-H., Klein, G., Natale, A., Packer, D., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.09.028 · Cited by 95
“Generally, the procedure is safe and effective (1), but the intense intraprocedural and post-procedural anticoagulation regimen used, together with extensive catheter manipulation and application of radiofrequency energy, may expose patients to an excessive risk for bleeding.”
BackgroundMethodInfluentialSelf-citationFredersdorf, S., WEBER, S., Jilek, C., Heinicke, N., von Bary, C., Jungbauer, C. G., Riegger, G. A. J., Hamer, O. W., & Jeron, A. (2009) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2009.01501.x · Cited by 95
Catheter Ablation of Atrial Fibrillation: State of the Art and Future Perspectives
Rottner, L., Bellmann, B., Lin, T., Reißmann, B., Tönnis, T., Schleberger, R., Nies, M., Jungen, C., Dinshaw, L., Klatt, N., et al. (2020) · Cardiology and Therapy · doi:10.1007/s40119-019-00158-2 · Cited by 94
Hohnloser, S. H., & Camm, A. J. (2013) · EP Europace · doi:10.1093/europace/eut241 · Cited by 93
“94%.(2) There is no consensus on the best anticoagulation approach to protect patients from thrombo-embolic events during ablation.”
BackgroundTrends in catheter ablation for atrial fibrillation in the United States
Kneeland, P. P., & Fang, M. C. (2009) · Journal of Hospital Medicine · doi:10.1002/jhm.445 · Cited by 95
Mun, H.-S., Joung, B., Uhm, J., Hwang, H. J., Kim, J., Lee, M., & Pak, H. (2012) · Heart · doi:10.1136/heartjnl-2011-301107 · Cited by 94
“In this study, we found no additional bene fi t of linear ablation in addition to CPVI in patients with PAF.”
BackgroundMethodInfluentialBeyer, E., Lee, R., & Lam, B.-K. (2009) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2008.11.031 · Cited by 93
Ripley, K. L., Gage, A. A., Olsen, D. B., Vleet, J. F. V., Lau, C., & Tse, H. (2007) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2007.00790.x · Cited by 93
Gaita, F., Di Donna, P., Olivotto, I., Scaglione, M., Ferrero, I., Montefusco, A., Caponi, D., Conte, M. R., Nistri, S., & Cecchi, F. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.12.087 · Cited by 91
Winkle, R. A., Mead, R. H., Engel, G., & Patrawala, R. A. (2011) · American Heart Journal · doi:10.1016/j.ahj.2011.04.013 · Cited by 92
La Meir, M., Gelsomino, S., Lucà, F., Pison, L., Parise, O., Colella, A., Gensini, G. F., Crijns, H., Wellens, F., & Maessen, J. G. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.04.044 · Cited by 90
“Nevertheless, the reported success rate is suboptimal in both fields [5,6], and the most beneficial ablation methodology for patients with lone atrial fibrillation (LAF) still remains a matter of debate.”
BackgroundTondo, C., Iacopino, S., Pieragnoli, P., Molon, G., Verlato, R., Curnis, A., Landolina, M., Allocca, G., Arena, G., Fassini, G. M., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.10.038 · Cited by 91
Melby, S. J., Lee, A. M., Zierer, A. F., Kaiser, S. P., Livhits, M. J., Boineau, J. P., Schuessler, R. B., & Damiano, R. J. (2008) · Heart Rhythm · doi:10.1016/j.hrthm.2008.06.009 · Cited by 91
Atrial fibrillation—the growing epidemic
Lip, G. Y. H., Kakar, P., & Watson, T. (2007) · Heart · doi:10.1136/hrt.2006.110791 · Cited by 90
Atrioesophageal Fistula in the Era of Atrial Fibrillation Ablation: A Review
Nair, G. M., Nery, P. B., Redpath, C. J., Lam, B.-K., & Birnie, D. H. (2013) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2013.12.012 · Cited by 90
Richter, B., Derntl, M., Marx, M., Lercher, P., & Gössinger, H. (2006) · American Heart Journal · doi:10.1016/j.ahj.2006.09.006 · Cited by 91
Sauren, L. D. C., Belle, Y. V., Roy, L. D., Pison, L., Meir, M. L., VEEN, F. H. V. D., Crijns, H. J. G. M., Jordaens, L. J. L. M., Mess, W. H., & Maessen, J. G. (2009) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2009.01509.x · Cited by 90
“neurological complications and examined during 3 different catheter-based PVI approaches: (1) segmental isolation with a conventional radiofrequency (RF) ablation catheter (CRF), ( 2 ) segmental isolation with an irrigated RF tip ablation catheter (IRF), and (3) circumferential isolation with a cryoballoon catheter (C…”
MethodAtrial fibrillation in highly trained endurance athletes — Description of a syndrome
Sanchis-Gomar, F., Perez-Quilis, C., Lippi, G., Cervellin, G., Leischik, R., Löllgen, H., Serrano-Ostáriz, E., & Lucia, A. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.10.047 · Cited by 95
Catheter Ablation for Atrial Fibrillation
Wazni, O. M., Wilkoff, B. L., & Saliba, W. I. (2011) · New England Journal of Medicine · doi:10.1056/nejmct1109977 · Cited by 89
Metadata
- Authors
- Cappato, R., Calkins, H., Chen, S.-A., Davies, W., Iesaka, Y., Kalman, J., Kim, Y.-H., Klein, G., Natale, A., Packer, D., Skanes, A., Ambrogi, F., & Biganzoli, E.
- Affiliations
- The Royal Melbourne Hospital (AU)
- ORCID
- Venue
- Circulation Arrhythmia and Electrophysiology
- Published
- 2010-02
- Volume
- 3
- Issue
- 1
- Pages
- 32-38
- ISSN
- 1941-3084 (ISSN-L)
- 1941-3149
- OpenAlex
- W2146673314
- Cited by
- 2,852
- References
- 34
- Citations by year
- 2026: 26 · 2025: 42 · 2024: 51 · 2023: 68 · 2022: 81 · 2021: 110 · 2020: 126 · 2019: 125 · 2018: 141 · 2017: 177 · 2016: 199 · 2015: 184 · 2014: 220 · 2013: 246 · 2012: 218
- FWCI
- 156.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation Arrhythmia and Electrophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- catheter ablation, atrial fibrillation, paroxysmal atrial fibrillation, persistent atrial fibrillation, ablation efficacy, ablation safety, procedural complications, CARTO system
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Anticoagulants, Atrial Fibrillation, Data Collection, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Treatment Outcome, Catheter Ablation, Young Adult
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