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Cited by 390Blood Pressure and Hypertension StudiesCardiovascular Health and Disease PreventionSodium Intake and Health

Home-Measured Blood Pressure Is a Stronger Predictor of Cardiovascular Risk Than Office Blood Pressure: The Finn-Home Study

Niiranen, Teemu J., Hänninen, Marjo-Riitta, Johansson, Jouni, Reunanen, Antti, Jula, Antti M.·2010·Hypertension
DOI 10.1161/hypertensionaha.109.149336
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Abstract

Previous studies with some limitations have provided equivocal results for the prognostic significance of home-measured blood pressure (BP). We investigated whether home-measured BP is more strongly associated with cardiovascular events and total mortality than is office BP. A prospective nationwide study was initiated in 2000 to 2001 on 2081 randomly selected subjects aged 45 to 74 years. Home and office BP were determined at baseline along with other cardiovascular risk factors. The primary end point was incidence of a cardiovascular event (cardiovascular mortality, nonfatal myocardial infarction, nonfatal stroke, hospitalization for heart failure, percutaneous coronary intervention, or coronary artery bypass graft surgery). The secondary end point was total mortality. After a mean follow-up of 6.8 years, 162 subjects had experienced a cardiovascular event, and 118 subjects had died. In Cox proportional hazard models adjusted for other cardiovascular risk factors, office BP (systolic/diastolic hazard ratio [HR] per 10/5 mm Hg increase in BP, 1.13/1.13; systolic/diastolic 95% confidence interval [CI], 1.05 to 1.22/1.05 to 1.22) and home BP (HR, 1.23/1.18; 95% CI, 1.13 to 1.34/1.10 to 1.27) were predictive of cardiovascular events. However, when both BPs were simultaneously included in the models, only home BP (HR, 1.22/1.15; 95% CI, 1.09 to 1.37/1.05 to 1.26), not office BP (HR, 1.01/1.06; 95% CI, 0.92 to 1.12/0.97 to 1.16), was predictive of cardiovascular events. Systolic home BP was the sole predictor of total mortality (HR, 1.11; 95% CI, 1.01/1.23). Our findings suggest that home-measured BP is prognostically superior to office BP. On the basis of the results of this and previous studies, it can be concluded that home BP measurement offers specific advantages more than conventional office measurement.

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  • Home blood pressure measurement has a stronger association with cardiovascular risk factors compared to office blood pressure.

    “For strict management of hypertension control, home BP measurement has increasingly emerged as a key metric, supported by research findings that show a stronger association with cardiovascular risk factors compared to office BP [4,5].”

    From The WHO Global report 2023 on hypertension warning the emerging hypertension burden in globe and its treatment strategy (2024) · cites this paper as [4]

    The Abstract and “BP and CV Risk” section report that home BP predicted cardiovascular events more strongly than office BP, supporting the comparison. But the study treated other cardiovascular risk factors as adjustment variables; it did not establish a stronger association between home BP and those risk factors. (LLM, conf=0.85)

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Research works printed but not linked: 1

  1. [25]25. Varis J, Savola H, Vesalainen R, Kantola I. Verenpainetaudin hoito- tasapaino ei ole Suomessa viela ¨ka ¨a ¨n hyva ¨. Suom Laakaril. 2008;63: 3289 -3295.

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Authors
Niiranen, T. J., Hänninen, M.-R., Johansson, J., Reunanen, A., & Jula, A. M.
Affiliations
  • Turku University Hospital (FI)
  • From the Population Studies Unit (T.J.N., M.-R.H., J.J., A.M.J.), National Institute for Health and Welfare, Turku, Finland; Department of Medicine (T.J.N.), Turku University Hospital, Turku, Finland; Living Conditions, Health and Wellbeing Unit (A.R.), National Institute for Health and Welfare, Helsinki, Finland.
ORCID
Venue
Hypertension
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2010-06
Volume
55
Issue
6
Pages
1346-1351
ISSN
  • 0194-911X (ISSN-L)
  • 1524-4563
DOI
10.1161/hypertensionaha.109.149336
OpenAlex
W2155309039
Cited by
390
References
29
Citations by year
2026: 16 · 2025: 12 · 2024: 19 · 2023: 29 · 2022: 27 · 2021: 23 · 2020: 21 · 2019: 26 · 2018: 33 · 2017: 19 · 2016: 22 · 2015: 28 · 2014: 34 · 2013: 29 · 2012: 32
FWCI
17.78
Type
journal article
Language
en
Open access
closed
Locations
  • Hypertension (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Työsuojelurahasto
  • Suomen Hammaslääkäriliitto
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
Keywords
home blood pressure monitoring, office blood pressure, cardiovascular risk prediction, cardiovascular events, all-cause mortality, systolic blood pressure, prognostic value
MeSH terms
Aged, Blood Pressure Determination, Cardiovascular Diseases, Cause of Death, Female, Finland, Humans, Hypertension, Male, Middle Aged, Office Visits, Predictive Value of Tests, Probability, Prognosis, Reproducibility of Results, Cohort Studies, Prevalence, Proportional Hazards Models, Survival Analysis, Risk Assessment, Blood Pressure Monitoring, Ambulatory

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