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Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
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“Telomere dysfunction also promotes progerin production in normal human fibroblasts upon prolonged in vitro culture, suggesting intimate links between telomere maintenance and progerin expression during normal aging (Cao et al., 2011).”
From The Hallmarks of Aging (2013) · cites this paper as Cao et al., 2011
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Metadata
- Authors
- Cao, K., Blair, C. D., Faddah, D. A., Kieckhaefer, J. E., Olive, M., Erdos, M. R., Nabel, E. G., & Collins, F. S.
- Venue
- Journal of Clinical Investigation
- Published
- 2011-07-01
- Volume
- 121
- Issue
- 7
- Pages
- 2833-2844
- ISSN
- 0021-9738
- Cited by
- 284
- References
- 9
- Language
- en
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