Lamin A Truncation in Hutchinson-Gilford Progeria

De Sandre-Giovannoli, Annachiara; Bernard, Rafaëlle; Cau, Pierre; Navarro, Claire; Amiel, Jeanne; Boccaccio, Irène; Lyonnet, Stanislas; Stewart, Colin L.; Munnich, Arnold; Le Merrer, Martine; Lévy, Nicolas

doi:10.1126/science.1084125

Cited by 1,346

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Lamin A Truncation in Hutchinson-Gilford Progeria

De Sandre-Giovannoli, Annachiara, Bernard, Rafaëlle, Cau, Pierre, Navarro, Claire, Amiel, Jeanne, Boccaccio, Irène, Lyonnet, Stanislas, Stewart, Colin L., Munnich, Arnold, Le Merrer, Martine, Lévy, Nicolas·2003·Science

DOI 10.1126/science.1084125

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Mutations in genes encoding protein components of the nuclear lamina, or factors affecting their maturation and dynamics, cause accelerated aging syndromes such as Hutchinson-Gilford and Néstor-Guillermo progeria syndromes.
“The nuclear lamina attracted the attention of aging researchers after the discovery that mutations in genes encoding protein components of this structure, or factors affecting their maturation and dynamics, cause accelerated aging syndromes such as the Hutchinson-Gilford and the Néstor-Guillermo progeria syndromes (HGPS and NGPS, respectively) (Cabanillas et al., 2011; De Sandre-Giovannoli et al.,”
From The Hallmarks of Aging (2013) · cites this paper as De Sandre-Giovannoli et al., 2003

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Clinical and epidemiological information are available online at www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?cmd=entry&id=176670.
10.1016/S0962-8924(02)02401-7 · DOI
10.1038/nrm879 · DOI
10.1086/341908 · DOI

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Authors: De Sandre-Giovannoli, A., Bernard, R., Cau, P., Navarro, C., Amiel, J., Boccaccio, I., Lyonnet, S., Stewart, C. L., Munnich, A., Le Merrer, M., & Lévy, N.
Affiliations: Inserm U491: «Génétique Médicale et Développement», Faculté de Médecine Timone, Marseille, France.
Venue: Science
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2003-06-27
Volume: 300
Issue: 5628
Pages: 2055-2055
ISSN: 0036-8075
1095-9203
DOI: 10.1126/science.1084125
Cited by: 1,346
References: 0
Language: en

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Lamin A Truncation in Hutchinson-Gilford Progeria

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