Is Social Jetlag Associated with an Adverse Endocrine, Behavioral, and Cardiovascular Risk Profile?
Open accessAbstract
Social jetlag represents the discrepancy between circadian and social clocks, which is measured as the difference in hours in midpoint of sleep between work days and free days. Previous studies have shown social jetlag to be associated with body mass index (BMI), glycated hemoglobin levels, heart rate, depressive symptoms, smoking, mental distress and alcohol use. The objective of our current study was to investigate, in a group of 145 apparently healthy participants (67 men and 78 women, aged 18-55 years, BMI 18-35 kg/m 2 ), the prevalence of social jetlag and its association with adverse endocrine, behavioral and cardiovascular risk profiles as measured in vivo. participants with ≥2 h social jetlag had higher 5-h cortisol levels, slept less during the week, were more often physically inactive and had an increased resting heart rate, compared with participants who had ≤1 h social jetlag. We therefore concluded that social jetlag is associated with an adverse endocrine, behavioral and cardiovascular risk profile in apparently healthy participants. These adverse profiles put healthy participants at risk for development of metabolic diseases and mental disorders, including diabetes and depression, in the near future.
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The greater the social jet lag, the greater the risk for obesity and diabetes.
“Approximately 70% of the population have noticeable social jet lag (i.e., their biological and social clocks differ by more than 1 hour) (154), and the greater the social jet lag, the greater the risk for obesity and diabetes (154-156).”
From Role of the circadian system in cardiovascular disease (2018) · cites this paper as [155]
Greater social jet lag is associated with increased heart rate and higher cortisol levels.
“The effects of social jet lag on the CV system have not been well studied, though it is reported that greater social jet lag is associated with increased HR and higher cortisol levels (155).”
From Role of the circadian system in cardiovascular disease (2018) · cites this paper as [155]
Social jetlag has been linked to measures of adiposity, heart rate, and higher cortisol levels in healthy individuals, and to higher glycated hemoglobin levels in patients with type 2 diabetes.
“SJL has been linked to measures of adiposity (11,15,16), heart rate (16,17), and higher cortisol levels in healthy individuals (16) and to higher glycated hemoglobin levels in patients with type 2 diabetes (18).”
From Social jetlag, chronotype, and cardiometabolic risk (2015) · cites this paper as [16]
Social jetlag was not associated with heart rate.
“In contrast to previous reports (16,17), we did not find SJL associated with heart rate.”
From Social jetlag, chronotype, and cardiometabolic risk (2015) · cites this paper as [16]
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- Authors
- Rutters, F., Lemmens, S. G., Adam, T. C., Bremmer, M. A., Elders, P. J., Nijpels, G., & Dekker, J. M.
- Affiliations
- Amsterdam Public Health (NL)
- Maastricht University (NL)
- Corresponding author
- Rutters, Femke
- Venue
- Journal of Biological Rhythms
- Publisher
- SAGE Publications
- Published
- 2014-09-24
- Volume
- 29
- Issue
- 5
- Pages
- 377-383
- ISSN
- 0748-7304 (ISSN-L)
- 1552-4531
- OpenAlex
- W2151411960
- Semantic Scholar
- 699a82a6ac66745af4aa943478fb69266e6ca744
- Cited by
- 274
- References
- 28
- Citations by year
- 2026: 7 · 2025: 24 · 2024: 28 · 2023: 32 · 2022: 28 · 2021: 32 · 2020: 33 · 2019: 27 · 2018: 19 · 2017: 16 · 2016: 17 · 2015: 11
- FWCI
- 20.36
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Biological Rhythms (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Research Publications (Maastricht University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Vrije Universiteit Amsterdam
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- social jetlag, circadian rhythm, sleep timing, cortisol, resting heart rate, physical inactivity, cardiovascular risk, metabolic risk, depression, healthy adults
- MeSH terms
- Adult, Behavior, Cardiovascular Diseases, Circadian Rhythm, Female, Heart Rate, Humans, Male, Risk Factors, Sleep, Body Mass Index, Jet Lag Syndrome, Endocrine Cells
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