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Nomenclature of monocytes and dendritic cells in blood

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Ziegler-Heitbrock, Loems, Ancuta, Petronela, Crowe, Suzanne, Dalod, Marc, Grau, Veronika, Hart, Derek N., Leenen, Pieter J. M., Liu, Yong-Jun, MacPherson, Gordon, Randolph, Gwendalyn J., Scherberich, Juergen, Schmitz, Juergen, Shortman, Ken, Sozzani, Silvano, Strobl, Herbert, Zembala, Marek, Austyn, Jonathan M., Lutz, Manfred B.·2010·Blood
DOI 10.1182/blood-2010-02-258558
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Abstract

Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community.

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Metadata

Authors
Ziegler-Heitbrock, L., Ancuta, P., Crowe, S., Dalod, M., Grau, V., Hart, D. N., Leenen, P. J. M., Liu, Y.-J., MacPherson, G., Randolph, G. J., Scherberich, J., Schmitz, J., Shortman, K., Sozzani, S., Strobl, H., Zembala, M., Austyn, J. M., & Lutz, M. B.
Venue
Blood
Publisher
American Society of Hematology
Published
2010-10-21
Volume
116
Issue
16
Pages
e74-e80
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
DOI
10.1182/blood-2010-02-258558
OpenAlex
W1984378291
Cited by
2,436
References
3
FWCI
37.58
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Nomenclature of monocytes and dendritic cells in blood. https://app.cochat.ai/papers/10.1182/blood-2010-02-258558
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Ziegler-Heitbrock, L., Ancuta, P., Crowe, S., Dalod, M., Grau, V., Hart, D. N., Leenen, P. J. M., Liu, Y.-J., MacPherson, G., Randolph, G. J., Scherberich, J., Schmitz, J., Shortman, K., Sozzani, S., Strobl, H., Zembala, M., Austyn, J. M., & Lutz, M. B. (2010). Nomenclature of monocytes and dendritic cells in blood. Blood. https://doi.org/10.1182/blood-2010-02-258558

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