Volumetric associations between uncinate fasciculus, amygdala, and trait anxiety
Open accessAbstract
BACKGROUND: Recent investigations of white matter (WM) connectivity suggest an important role of the uncinate fasciculus (UF), connecting anterior temporal areas including the amygdala with prefrontal-/orbitofrontal cortices, for anxiety-related processes. Volume of the UF, however, has rarely been investigated, but may be an important measure of structural connectivity underlying limbic neuronal circuits associated with anxiety. Since UF volumetric measures are newly applied measures, it is necessary to cross-validate them using further neural and behavioral indicators of anxiety. RESULTS: In a group of 32 subjects not reporting any history of psychiatric disorders, we identified a negative correlation between left UF volume and trait anxiety, a finding that is in line with previous results. On the other hand, volume of the left amygdala, which is strongly connected with the UF, was positively correlated with trait anxiety. In addition, volumes of the left UF and left amygdala were inversely associated. CONCLUSIONS: The present study emphasizes the role of the left UF as candidate WM fiber bundle associated with anxiety-related processes and suggests that fiber bundle volume is a WM measure of particular interest. Moreover, these results substantiate the structural relatedness of UF and amygdala by a non-invasive imaging method. The UF-amygdala complex may be pivotal for the control of trait anxiety.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Reduced grey matter volume in the mPFC and weaker integrity of the uncinate fasciculus have been reported in adults with anxious temperament and anxiety disorders.
“Structural abnormalities, such as reduced grey matter volume in the mPFC and weaker integrity of the uncinate fasciculus, have been reported in adults with anxious temperament and anxiety disorders24–28.”
From Multimodal evidence for delayed threat extinction learning in adolescence and young adulthood (2019) · cites this paper as [25]
Weaker structural integrity of the uncinate fasciculus has been found in populations with anxious temperament, suggesting that this tract may play a crucial role in anxiety aetiology.
“Notably, weaker structural integrity of the uncinate fasciculus has been found in populations with anxious temperament24–27,32, suggesting that this tract may play a crucial role in anxiety aetiology.”
From Multimodal evidence for delayed threat extinction learning in adolescence and young adulthood (2019) · cites this paper as [25]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Advances in functional and structural MR image analysis and implementation as FSL
Smith, S. M., Jenkinson, M., Woolrich, M. W., Beckmann, C. F., Behrens, T. E. J., Johansen-Berg, H., Bannister, P. R., De Luca, M., Drobnjak, I., Flitney, D. E., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.07.051 · Cited by 13,630 · see citing works
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391 · cited 1× · see citing works
“The amygdala has been shown to be part of a limbic network that is hyper-responsive in individuals with increased anxiety [9] and in patients with anxiety disorders [10].”
BackgroundAnxiety, sensitivity, anxiety frequency, and the prediction of fearfulness
Reiss, S., Peterson, R. A., Gursky, D. M., & McNally, R. J. (1986) · Behaviour Research and Therapy · doi:10.1016/0005-7967(86)90143-9 · Cited by 3,169 · see citing works
A CLASSIFICATION OF HAND PREFERENCE BY ASSOCIATION ANALYSIS
Annett, M. (1970) · British Journal of Psychology · doi:10.1111/j.2044-8295.1970.tb01248.x · Cited by 2,305 · see citing works
Reproducibility of quantitative tractography methods applied to cerebral white matter
Wakana, S., Caprihan, A., Panzenboeck, M. M., Fallon, J. H., Perry, M., Gollub, R. L., Hua, K., Zhang, J., Jiang, H., Dubey, P., et al. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.02.049 · Cited by 1,686 · see citing works
A diffusion tensor imaging tractography atlas for virtual in vivo dissections.
CATANI, M., & THIEBAUTDESCHOTTEN, M. (2008) · Cortex · doi:10.1016/j.cortex.2008.05.004 · Cited by 1,642 · see citing works
Puzzlingly High Correlations in fMRI Studies of Emotion, Personality, and Social Cognition
Vul, E., Harris, C., Winkielman, P., & Pashler, H. (2009) · Perspectives on Psychological Science · doi:10.1111/j.1745-6924.2009.01125.x · Cited by 1,475 · cited 1× · see citing works
“9) [34] can principally be obtained with the applied methods.”
MethodRegional dissociations within the hippocampus-memory and anxiety
Bannerman, D. M., Rawlins, J. N. P., McHugh, S. B., Deacon, R. M. J., Yee, B. K., Bast, T., Zhang, W.-N., Pothuizen, H. H. J., & Feldon, J. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.03.004 · Cited by 1,462 · see citing works
Type I and Type II error concerns in fMRI research: re-balancing the scale
Lieberman, M. D., & Cunningham, W. A. (2009) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsp052 · Cited by 1,342 · see citing works
Cortical pathways to the mammalian amygdala
McDonald, A. J. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00003-3 · Cited by 1,303 · see citing works
Amygdala–frontal connectivity during emotion regulation
Banks, S. J., Eddy, K. T., Angstadt, M., Nathan, P. J., & Phan, K. L. (2007) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsm029 · Cited by 1,187 · cited 1× · see citing works
“[23]) and are critical for reappraisal-initiated reduction of negative affects [24].”
BackgroundIncreased Amygdala and Insula Activation During Emotion Processing in Anxiety-Prone Subjects
Stein, M. B., Simmons, A. N., Feinstein, J. S., & Paulus, M. P. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.2.318 · Cited by 851 · see citing works
Kim, M. J., Loucks, R. A., Palmer, A. L., Brown, A. C., Solomon, K. M., Marchante, A. N., & Whalen, P. J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.04.025 · Cited by 838 · see citing works
Das State-Trait-Angstinventar (STAI) : theoretische Grundlagen und Handanweisung
Laux, L. (1981) · Beltz eBooks · Cited by 750 · see citing works
Etkin, A., Klemenhagen, K. C., Dudman, J. T., Rogan, M. T., Hen, R., Kandel, E. R., & Joy Hirsch, C. (2004) · Neuron · doi:10.1016/j.neuron.2004.12.006 · Cited by 679 · see citing works
Monkey to human comparative anatomy of the frontal lobe association tracts
Thiebaut de Schotten, M., Dell’Acqua, F., Valabregue, R., & Catani, M. (2012) · Cortex · doi:10.1016/j.cortex.2011.10.001 · Cited by 632 · see citing works
How to Regulate Emotion? Neural Networks for Reappraisal and Distraction
Kanske, P., Heissler, J., Schönfelder, S., Bongers, A., & Wessa, M. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq216 · Cited by 589 · see citing works
Imaging cortical association tracts in the human brain using diffusion‐tensor‐based axonal tracking
Mori, S., Kaufmann, W. E., Davatzikos, C. A., Stieltjes, B., Amodei, L., Fredericksen, K., Pearlson, G. D., Melhem, E. R., Solaiyappan, M., Raymond, G. V., et al. (2002) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10074 · Cited by 558 · see citing works
Efferent Association Pathways from the Rostral Prefrontal Cortex in the Macaque Monkey
Petrides, M., & Pandya, D. Ν. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2419-07.2007 · Cited by 437 · see citing works
The structural integrity of an amygdala-prefrontal pathway predicts trait anxiety
Kim, M. J., & Whalen, P. J. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2335-09.2009 · Cited by 433 · see citing works
The connections of the amygdala and of the anterior temporal cortex in the human brain.
Klingler, J., & Gloor, P. (1960) · Journal of Comparative Neurology · doi:10.1002/cne.901150305 · Cited by 404 · see citing works
Hahn, A., Stein, P., Windischberger, C., Weissenbacher, A., Spindelegger, C., Moser, E., Kasper, S., & Lanzenberger, R. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.02.064 · Cited by 385 · see citing works
Neuroanatomical correlates of a lactate-induced anxiety attack.
Reiman, E., Raichle, M., Robins, E., Mintun, M., Fusselman, M. J., Fox, P. T., Price, J., & Hackman, K. A. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810060013003 · Cited by 319 · see citing works
Topography of the uncinate fascicle and adjacent temporal fiber tracts
Ebeling, U., & Cramon, D. V. (1992) · Acta Neurochirurgica · doi:10.1007/bf01406373 · Cited by 300 · see citing works
Phan, K. L., Orlichenko, A., Boyd, E., Angstadt, M., Coccaro, E. F., Liberzon, I., & Arfanakis, K. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.02.028 · Cited by 226 · see citing works
Neuroanatomical Correlates of Extraversion and Neuroticism
Wright, C. I., Williams, D., Feczko, E., Barrett, L. F., Dickerson, B. C., Schwartz, C., & Wedig, M. M. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhj118 · Cited by 225 · see citing works
Amygdala gray matter concentration is associated with extraversion and neuroticism
Omura, K., Constable, R. T., & Canli, T. (2005) · Neuroreport · doi:10.1097/01.wnr.0000186596.64458.76 · Cited by 220 · see citing works
Increased Amygdala and Insula Activation During Emotion Processing in Anxiety-Prone Subjects
Stein, M. B. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.164.2.318 · Cited by 212 · see citing works
Liao, W., Qiu, C., Gentili, C., Walter, M., Pan, Z., Ding, J., Zhang, W., Gong, Q., & Chen, H. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015238 · Cited by 180 · see citing works
Feeling anxious: anticipatory amygdalo-insular response predicts the feeling of anxious anticipation
Carlson, J. M., Greenberg, T., Rubin, D., & Mujica-Parodi, L. R. (2010) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq017 · Cited by 170 · see citing works
Pugliese, L., Catani, M., Ameis, S. H., Dell’Acqua, F., de Schotten, M. T., Murphy, C. M., Robertson, D., Deeley, Q., Daly, E., & Murphy, D. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.014 · Cited by 170 · see citing works
Neural correlates of trait anxiety in fear extinction
Sehlmeyer, C., Dannlowski, U., Schöning, S., Kugel, H., Pyka, M., Pfleiderer, B., Zwitserlood, P., Schiffbauer, H., Heindel, W., Arolt, V., et al. (2011) · Psychological Medicine · doi:10.1017/s0033291710001248 · Cited by 165 · see citing works
Deep and Superficial Amygdala Nuclei Projections RevealedIn Vivoby Probabilistic Tractography
Bach, D. R., Behrens, T. E. J., Garrido, L., Weiskopf, N., & Dolan, R. J. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2744-10.2011 · Cited by 151 · see citing works
Hippocampal morphometry in depressed patients and control subjects: relations to anxiety symptoms
Rusch, B. D., Abercrombie, H. C., Oakes, T. R., Schaefer, S. M., & Davidson, R. J. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01248-3 · Cited by 139 · see citing works
Connectivity-based segmentation of human amygdala nuclei using probabilistic tractography
Saygin, Z. M., Osher, D. E., Augustinack, J. C., Fischl, B. R., & Gabrieli, J. D. E. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.03.006 · Cited by 123 · see citing works
Kühn, S., Schubert, F., & Gallinat, J. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.06.003 · Cited by 102 · see citing works
Neural Correlates of Anxiety in Healthy Volunteers: A Voxel-Based Morphometry Study
Spampinato, M. V., Wood, J. N., Simone, V. D., & Grafman, J. H. (2009) · Journal of Neuropsychiatry · doi:10.1176/jnp.2009.21.2.199 · Cited by 99 · see citing works
Pilot multimodal twin imaging study of generalized anxiety disorder
Hettema, J. M., Kettenmann, B., Ahluwalia, V., McCarthy, C., Kates, W. R., Schmitt, J. E., Silberg, J. L., Neale, M. C., Kendler, K. S., & Fatouros, P. P. (2011) · Depression and Anxiety · doi:10.1002/da.20901 · Cited by 91 · see citing works
Structural evidence for involvement of a left amygdala-orbitofrontal network in subclinical anxiety
Blackmon, K., Barr, W. B., Carlson, C., Devinsky, O., DuBois, J., Pogash, D., Quinn, B. T., Kuzniecky, R., Halgren, E., & Thesen, T. (2011) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2011.05.007 · Cited by 90 · see citing works
Baur, V., Brühl, A. B., Herwig, U., Eberle, T., Rufer, M., Delsignore, A., Jäncke, L., & Hänggi, J. (2011) · Human Brain Mapping · doi:10.1002/hbm.21447 · Cited by 88 · see citing works
Self-citationWhite matter alterations in social anxiety disorder
Baur, V., Hänggi, J., Rufer, M., Delsignore, A., Jäncke, L., Herwig, U., & Beatrix Brühl, A. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.05.007 · Cited by 86 · see citing works
Self-citationDie “ARES-Skalen” zur Erfassung der individuellen BIS- und BAS-Sensitivität
Hartig, J., & Moosbrugger, H. (2003) · Zeitschrift für Differentielle und Diagnostische Psychologie · doi:10.1024/0170-1789.24.4.293 · Cited by 46 · see citing works
Digit symbol performance of subjects varying in anxiety and defensiveness.
Boor, M., & Schill, T. R. (1967) · Journal of Consulting Psychology · doi:10.1037/h0025147 · Cited by 41 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Eysenck HJ Eysenck SBG Manual of the Eysenck Personality Inventory 1964 London: University of London Press
Cited by
Sorted by citations
Dissecting the uncinate fasciculus: disorders, controversies and a hypothesis.
Von Der Heide, R. J., Skipper, L. M., Klobusicky, E., & Olson, I. R. (2013) · Brain · doi:10.1093/brain/awt094 · Cited by 829 · see citing works
Brühl, A. B., Delsignore, A., Komossa, K., & Weidt, S. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.08.003 · Cited by 439 · see citing works
Baur, V., Hänggi, J., Langer, N., & Jäncke, L. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.003 · Cited by 258 · see citing works
Self-citationQin, S., Young, C. B., Duan, X., Chen, T., Supekar, K., & Menon, V. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.10.006 · Cited by 249 · see citing works
Happy heart syndrome: role of positive emotional stress in takotsubo syndrome
Ghadri, J. R., Sarcon, A. K., Diekmann, J., Bataiosu, R. D., Cammann, V. L., Jurisic, S., Napp, L. C., Jaguszewski, M. J., Scherff, F., Brugger, P., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehv757 · Cited by 187 · see citing works
Self-citationBalaban, C. D., FURMAN, J. M. R., & Staab, J. P. (2013) · Seminars in Neurology · doi:10.1055/s-0033-1356462 · Cited by 133 · see citing works
Insecure attachment during infancy predicts greater amygdala volumes in early adulthood
Moutsiana, C., Johnstone, T., Murray, L., Fearon, P., Cooper, P. J., Pliatsikas, C., Goodyer, I., & Halligan, S. L. (2015) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12317 · Cited by 112 · see citing works
Janiri, D., Sani, G., Rossi, P. D., Piras, F., Iorio, M., Banaj, N., Giuseppin, G., Spinazzola, E., Maggiora, M., Ambrosi, E., et al. (2017) · Bipolar Disorders · doi:10.1111/bdi.12516 · Cited by 99 · see citing works
Mincic, A. M. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.08.007 · Cited by 90 · see citing works
Increased cortical thickness in a frontoparietal network in social anxiety disorder
Brühl, A. B., Hänggi, J., Baur, V., Rufer, M., Delsignore, A., Weidt, S., Jäncke, L., & Herwig, U. (2013) · Human Brain Mapping · doi:10.1002/hbm.22378 · Cited by 87 · see citing works
Self-citationWorbe, Y., Sgambato, V., Epinat‐Duclos, J., Chaigneau, M., Tandé, D., François, C., Féger, J., & Tremblay, L. (2012) · Cortex · doi:10.1016/j.cortex.2012.08.020 · Cited by 86 · see citing works
Aberrant functional connectivity of resting state networks associated with trait anxiety
Modi, S., Kumar, M., Kumar, P., & Khushu, S. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2015.07.006 · Cited by 84 · see citing works
Besteher, B., Gaser, C., & Nenadić, I. (2020) · Neuropsychobiology · doi:10.1159/000501024 · Cited by 83 · see citing works
Smoller, J. W., Gallagher, P., Duncan, L. E., McGrath, L. M., Haddad, S. A., Holmes, A. J., Wolf, A. B., Hilker, S., Block, S. R., Weill, S. R., et al. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.12.018 · Cited by 81 · see citing works
Perez, D. L., Williams, B., Matin, N., LaFrance, W. C., Jr., Costumero, V., Fricchione, G. L., Sepulcre, J., Keshavan, M. S., & Dickerson, B. C. (2017) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2017-316359 · Cited by 77 · see citing works
White matter integrity alterations in post‐traumatic stress disorder
O'Doherty, D. C. M., Ryder, W., Paquola, C., Tickell, A. M., Chan, C., Hermens, D. F., Bennett, M. R., & Lagopoulos, J. (2017) · Human Brain Mapping · doi:10.1002/hbm.23920 · Cited by 71 · see citing works
Tian, X. S., Wei, D., Du, X., Wang, K., Yang, J., Liu, W., Meng, J., Liu, H., Liu, G., & Qiu, J. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.03.024 · Cited by 71 · see citing works
Modi, S., Trivedi, R., Singh, K., Kumar, P., Rathore, R. K. S., Tripathi, R. P., & Khushu, S. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.10.007 · Cited by 69 · see citing works
Jamieson, D., Broadhouse, K. M., Lagopoulos, J., & Hermens, D. F. (2019) · Sleep Medicine · doi:10.1016/j.sleep.2019.08.013 · Cited by 63 · see citing works
Lifespan anxiety is reflected in human amygdala cortical connectivity
He, Y., Xu, T., Zhang, W., & Zuo, X. (2015) · Human Brain Mapping · doi:10.1002/hbm.23094 · Cited by 62 · see citing works
Disorders and borders: Psychiatric genetics and nosology
Smoller, J. W. (2013) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32174 · Cited by 66 · see citing works
Neurobiological candidate endophenotypes of social anxiety disorder
Bas‐Hoogendam, J. M., Blackford, J. U., Brühl, A. B., Blair, K. S., van der Wee, N. J. A., & Westenberg, P. M. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.040 · Cited by 63 · see citing works
Shekari, E., & Nozari, N. (2023) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2023.1139292 · Cited by 67 · see citing works
Donzuso, G., Cerasa, A., Gioia, M. C., Caracciolo, M., & Quattrone, A. (2014) · Brain and Behavior · doi:10.1002/brb3.232 · Cited by 58 · see citing works
Markett, S. A., Weber, B., Voigt, G., Montag, C., Felten, A., Elger, C. E., & Reuter, M. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.02.056 · Cited by 56 · see citing works
Albaugh, M. D., Nguyen, T., Ducharme, S., Collins, D. L., Botteron, K. N., D’Alberto, N., Evans, A. C., Karama, S., & Hudziak, J. J. (2017) · Biological Psychology · doi:10.1016/j.biopsycho.2017.02.002 · Cited by 55 · see citing works
Steiger, V. R., Brühl, A. B., Weidt, S., Delsignore, A., Rufer, M., Jäncke, L., Herwig, U., & Hänggi, J. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.217 · Cited by 55 · see citing works
Self-citationFunctional neurological disorder and placebo and nocebo effects: shared mechanisms
Fiorio, M., Braga, M., Marotta, A., Villa‐Sánchez, B., Edwards, M. J., Tinazzi, M., & Barbiani, D. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00711-z · Cited by 56 · see citing works
Nikolova, Y. S., Misquitta, K. A., Rocco, B. R., Prévot, T. D., Knodt, A. R., Ellegood, J., Voineskos, A. N., Lerch, J. P., Hariri, A. R., Sibille, E. L., et al. (2018) · Translational Psychiatry · doi:10.1038/s41398-017-0083-5 · Cited by 51 · see citing works
Wei, D., Du, X., Li, W., Chen, Q., Li, H., Hao, X., Zhang, L., Hitchman, G., Zhang, Q., & Qiu, J. (2014) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsu033 · Cited by 52 · see citing works
Mindfulness-Based Stress Reduction, Fear Conditioning, and The Uncinate Fasciculus: A Pilot Study
Hölzel, B. K., Brunsch, V., Gard, T., Greve, D. N., Koch, K., Sorg, C., Lazar, S. W., & Milad, M. R. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00124 · Cited by 55 · see citing works
Uvnäs‐Moberg, K., Groß, M. M., Calleja‐Agius, J., & Turner, J. D. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1272270 · Cited by 53 · see citing works
Howell, B., McMurray, M. S., Guzman, D., Nair, G., Shi, Y., McCormack, K. M., Hu, X. P., Styner, M. A., & Sánchez, M. M. (2016) · Social Neuroscience · doi:10.1080/17470919.2016.1200481 · Cited by 46 · see citing works
Altered Uncinate Fasciculus Microstructure in Childhood Anxiety Disorders in Boys But Not Girls
Tromp, D., Williams, L. E., Fox, A. S., Oler, J. A., Roseboom, P. H., Rogers, G. M., Benson, B. E., Alexander, A. L., Pine, D. S., & Kalin, N. H. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.18040425 · Cited by 49 · see citing works
The role of negative emotions in sex differences in pain sensitivity
Zhang, H., Bi, Y., Hou, X., Lu, X., Tu, Y., & Hu, L. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118685 · Cited by 47 · see citing works
Association Between Accelerometer-Derived Physical Activity Measurements and Brain Structure
Fox, F. A. U., Diers, K., Lee, H. L., Mayr, A. J., Reuter, M., Breteler, M. M. B., & Aziz, N. A. (2022) · Neurology · doi:10.1212/wnl.0000000000200884 · Cited by 39 · see citing works
Modi, S., Rana, P., Kaur, P., Rani, N., & Khushu, S. (2014) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2014.03.001 · Cited by 41 · see citing works
Lü, M., Yang, C., Chu, T., & Wu, S. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00704 · Cited by 40 · see citing works
Impartiality in humans is predicted by brain structure of dorsomedial prefrontal cortex
Baumgärtner, T., Schiller, B., Hill, C., & Knoch, D. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.05.047 · Cited by 39 · see citing works
Amygdala volume and hypothalamic-pituitary-adrenal axis reactivity to social stress
Barry, T. J., Murray, L., Fearon, P. R. M., Moutsiana, C., Johnstone, T., & Halligan, S. L. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.07.487 · Cited by 39 · see citing works
A comparison of structural connectivity in anxious depression versus non-anxious depression
Delaparte, L., Yeh, F.-C. F., Adams, P., Malchow, A. L., Trivedi, M. H., Oquendo, M. A., Deckersbach, T., Ogden, R. T., Pizzagalli, D. A., D, M. F. M., et al. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.01.012 · Cited by 37 · see citing works
Günther, V., Ihme, K. A., Kersting, A., Hoffmann, K., Lobsien, D., & Suslow, T. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.01.034 · Cited by 36 · see citing works
Zuurbier, L. A., Nikolova, Y. S., Åhs, F., & Hariri, A. R. (2013) · Emotion · doi:10.1037/a0031163 · Cited by 37 · see citing works
Kaufmann, L., Baur, V., Hänggi, J., Jäncke, L., Piccirelli, M., Kollias, S., Schnyder, U., Pasternak, O., Martin-Söelch, C., & Milos, G. F. (2017) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2017.03.014 · Cited by 36 · see citing works
Self-citationd’Arbeloff, T. C., Kim, M. J., Knodt, A. R., Radtke, S. R., Brigidi, B. D., & Hariri, A. R. (2018) · Emotion · doi:10.1037/emo0000447 · Cited by 36 · see citing works
Kessler, R., Schmitt, S., Sauder, T., Stein, F., Yüksel, D., Grotegerd, D., Dannlowski, U., Hahn, T., Dempfle, A., Sommer, J. B., et al. (2020) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2020.00028 · Cited by 34 · see citing works
Warnell, K. R., Pecukonis, M., & Redcay, E. (2017) · Development and Psychopathology · doi:10.1017/s0954579417001626 · Cited by 33 · see citing works
Spielberg, J. M., Schwarz, J. M., & Matyi, M. A. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100791 · Cited by 34 · see citing works
Winkelmann, T., Grimm, O., Pohlack, S. T., Nees, F., Cacciaglia, R., Dinu-Biringer, R., Steiger, F., Wicking, M., Ruttorf, M., Schad, L. R., et al. (2016) · Brain Structure and Function · doi:10.1007/s00429-015-1013-z · Cited by 33 · see citing works
Dufford, A. J., Evans, G. W., Dmitrieva, J., Swain, J. E., Liberzon, I., & Kim, P. (2020) · Human Brain Mapping · doi:10.1002/hbm.25031 · Cited by 30 · see citing works
Multimodal evidence for delayed threat extinction learning in adolescence and young adulthood
Morriss, J., Christakou, A., & van Reekum, C. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-44150-1 · Cited by 32 · see citing works
Hirakawa, H., Akiyoshi, J., Muronaga, M., Tanaka, Y., Ishitobi, Y., Inoue, A., Oshita, H., Aizawa, S., Masuda, K., Higuma, H., et al. (2016) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651501.2016.1144772 · Cited by 30 · see citing works
Hu, Y., Moore, M., Bertels, Z., Phan, K. L., Dolcos, F., & Dolcos, S. M. (2017) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.11.008 · Cited by 29 · see citing works
Jamieson, D., Shan, Z., Lagopoulos, J., & Hermens, D. F. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101450 · Cited by 28 · see citing works
A large normative connectome for exploring the tractographic correlates of focal brain interventions
Elias, G. J. B., Germann, J., Joel, S. E., Li, N., Horn, A., Boutet, A., & Lozano, A. M. (2024) · Scientific Data · doi:10.1038/s41597-024-03197-0 · Cited by 27 · see citing works
Fronto-temporal white matter connectivity predicts reversal learning errors
Alm, K. H., Rolheiser, T. M., Mohamed, F. B., & Olson, I. R. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00343 · Cited by 25 · see citing works
Jamieson, D., Kannis‐Dymand, L., Beaudequin, D. A., Schwenn, P., Shan, Z., McLoughlin, L. T., Lagopoulos, J., & Hermens, D. F. (2021) · Journal of Adolescence · doi:10.1016/j.adolescence.2021.08.002 · Cited by 26 · see citing works
Zhang, R., Chen, Z., Xu, T., Zhang, L., & Feng, T. (2020) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2020.107571 · Cited by 26 · see citing works
Pereira, V., Marques, P., Magalhães, R. J. D. S., Português, J., Calvo, L., Cerqueira, J., & Sousa, N. (2015) · European Heart Journal Acute Cardiovascular Care · doi:10.1177/2048872615568968 · Cited by 24 · see citing works
Jamieson, D., Broadhouse, K. M., McLoughlin, L. T., Schwenn, P., Parker, M. J., Lagopoulos, J., & Hermens, D. F. (2020) · Journal of Adolescence · doi:10.1016/j.adolescence.2020.06.008 · Cited by 23 · see citing works
Zhang, R., Chen, Z., Liu, P., & Feng, T. (2019) · Psychophysiology · doi:10.1111/psyp.13495 · Cited by 23 · see citing works
Keerie, A. F. A., Brown-Wright, H., Kirkland, I., Grierson, A. J., Alix, J. J. P., Hölscher, C., & Mead, R. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-96418-0 · Cited by 24 · see citing works
Sotoudeh, N., Namavar, M. R., Bagheri, F., & Zarifkar, A. (2022) · Brain and Behavior · doi:10.1002/brb3.2616 · Cited by 23 · see citing works
Sekiguchi, A., Sugiura, M., Taki, Y., Kotozaki, Y., Nouchi, R., Takeuchi, H., Araki, T., Hanawa, S., Nakagawa, S., Miyauchi, C. M., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0083967 · Cited by 24 · see citing works
Autism and Anxiety: Etiologic Factors and Transdiagnostic Processes
Mazefsky, C. A., & Herrington, J. D. (2014) · Autism and child psychopathology series · doi:10.1007/978-3-319-06796-4_7 · Cited by 21 · see citing works
Brown, S. S. G., Rutland, J. W., Verma, G., Feldman, R. E., Schneider, M., Delman, B. N., Murrough, J., & Balchandani, P. (2019) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2019.07.010 · Cited by 20 · see citing works
Castagna, P. J., Roye, S., Calamia, M. R., Owens-French, J., Davis, T. E., & Greening, S. G. (2017) · Brain Imaging and Behavior · doi:10.1007/s11682-017-9772-1 · Cited by 20 · see citing works
Bourgin, J., Cachia, A., Boumezbeur, F., Djemaï, B., Bottlaender, M., Duchesnay, É., Mériaux, S., & Jay, T. M. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.02.010 · Cited by 20 · see citing works
Muncy, N. M., Kimbler, A., Hedges‐Muncy, A., McMakin, D. L., & Mattfeld, A. T. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.102937 · Cited by 17 · see citing works
Suffren, S., Chauret, M., Nassim, M., Leporé, F., & Maheu, F. S. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.01.028 · Cited by 18 · see citing works
Affective Symptoms and White Matter Changes in Brain Tumor Patients
Richter, A., Woernle, C. M., Krayenbühl, N., Kollias, S. S., & Bellut, D. (2015) · World Neurosurgery · doi:10.1016/j.wneu.2015.05.031 · Cited by 18 · see citing works
Neuroanatomical correlates of individual differences in social anxiety in a non-clinical population
Tian, X. S., Hou, X., Wang, K., Wei, D., & Qiu, J. (2015) · Social Neuroscience · doi:10.1080/17470919.2015.1091037 · Cited by 18 · see citing works
Modi, S., Thaploo, D., Kumar, P., & Khushu, S. (2018) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2018.11.008 · Cited by 18 · see citing works
Díaz, D. E., Tseng, W., & Michalska, K. J. (2024) · BMC Psychiatry · doi:10.1186/s12888-023-05403-6 · Cited by 17 · see citing works
Girls' internalizing symptoms and white matter tracts in Cortico-Limbic circuitry
Ali, O. M., Vandermeer, M. R. J., Sheikh, H. I., Joanisse, M. F., & Hayden, E. P. (2018) · NeuroImage Clinical · doi:10.1016/j.nicl.2018.101650 · Cited by 16 · see citing works
Research progress on the neural circuits mechanisms of anxiety
Gong, W. (2025) · Frontiers in Neural Circuits · doi:10.3389/fncir.2025.1609145 · Cited by 13 · see citing works
Parsaei, M., Hasehmi, S. M., Seyedmirzaei, H., Cattarinussi, G., Sambataro, F., Brambilla, P., & Delvecchio, G. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.118 · Cited by 13 · see citing works
Limbic and prefrontal neural volume modulate social anxiety in children at temperamental risk
Auday, E. S., & Pérez‐Edgar, K. E. (2019) · Depression and Anxiety · doi:10.1002/da.22941 · Cited by 12 · see citing works
White Matter-Based Structural Brain Network of Anxiety
Lee, K. S., & Lee, S. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-32-9705-0_4 · Cited by 14 · see citing works
Avnioğlu, S., Velioğlu, H. A., Çankaya, Ş., & Yuluğ, B. (2021) · Neuroreport · doi:10.1097/wnr.0000000000001682 · Cited by 12 · see citing works
Li, C., Su, S., Wu, H., & Zhu, Y. (2018) · Neuroreport · doi:10.1097/wnr.0000000000000982 · Cited by 12 · see citing works
Ehlers, M. R., Nold, J. I., Kuhn, M., Klingelhöfer-Jens, M., & Lonsdorf, T. B. (2020) · Scientific Reports · doi:10.1038/s41598-020-76683-1 · Cited by 14 · see citing works
Ye, J., Shen, Z., Xu, X., Yang, S., Chen, W., Liu, X., Lü, Y., Liu, F., Lü, J., Li, N., et al. (2017) · Neuroreport · doi:10.1097/wnr.0000000000000733 · Cited by 12 · see citing works
Pines, A. R., Sacchet, M. D., Kullar, M., Ma, J., & Williams, L. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-32394-2 · Cited by 10 · see citing works
Jamieson, D., Schwenn, P., Beaudequin, D. A., Shan, Z., McLoughlin, L. T., Lagopoulos, J., & Hermens, D. F. (2020) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10077 · Cited by 10 · see citing works
Impact of White Matter Dissection in Microneurosurgical Procedures
Güngör, A., Gurses, M. E., Demirtaş, O. K., Rahmanov, S., & Türe, U. (2023) · Springer eBooks · doi:10.1007/978-981-99-3412-6_3 · Cited by 9 · see citing works
Long-Term Effects of Postearthquake Distress on Brain Microstructural Changes
Sekiguchi, A., Kotozaki, Y., Sugiura, M., Nouchi, R., Takeuchi, H., Hanawa, S., Nakagawa, S., Miyauchi, C. M., Araki, T., Sakuma, A., et al. (2014) · BioMed Research International · doi:10.1155/2014/180468 · Cited by 10 · see citing works
Amygdala fMRI Signal as a Predictor of Reaction Time
Riedel, P., Jacob, M. J., Müller, D. K., Vetter, N. C., Smolka, M. N., & Marxen, M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00516 · Cited by 9 · see citing works
Jamieson, D., Shan, Z., Sacks, D. D., Boyes, A., Lagopoulos, J., & Hermens, D. F. (2022) · The Journal of Early Adolescence · doi:10.1177/02724316221104222 · Cited by 9 · see citing works
Guo, Y., Liu, S., Poletti, S., Liu, W., Liu, Y., Zhao, J., Xiong, Q., Zheng, H., Wei, D., Li, J., et al. (2025) · Psychological Medicine · doi:10.1017/s0033291725100780 · Cited by 7 · see citing works
Porfido, T., de Souza, N. L., Brown, A. M., Buckman, J. F., Fanning, B. D., Parrott, J. S., & Esopenko, C. (2021) · Concussion · doi:10.2217/cnc-2020-0023 · Cited by 7 · see citing works
Burrows, C. A., Lasch, C., Gross, J., Girault, J. B., Rutsohn, J., Wolff, J. J., Swanson, M. R., Lee, C.-M., Dager, S. R., Cornea, E. A., et al. (2023) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2023.101333 · Cited by 7 · see citing works
Psychological characteristics associated with the brain volume of patients with fibromyalgia
Izuno, S., Yoshihara, K., Hosoi, M., Eto, S., Hirabayashi, N., Todani, T., Gondo, M., Hayaki, C., Anno, K., Hiwatashi, A., et al. (2023) · BioPsychoSocial Medicine · doi:10.1186/s13030-023-00293-2 · Cited by 5 · see citing works
Ng, R., Brown, T. T., Järvinen, A. M., Erhart, M. J., Korenberg, J. R., Bellugi, U., & Halgren, E. (2015) · Social Neuroscience · doi:10.1080/17470919.2015.1057294 · Cited by 6 · see citing works
Squarcina, L., Delvecchio, G., Nobile, M., Mauri, M., Madonna, D., Bonivento, C., Garzitto, M., Piccin, S., Molteni, M., Tomasino, B., et al. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00763 · Cited by 5 · see citing works
Cornforth, E., & Schramm, K. (2021) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2021.101387 · Cited by 4 · see citing works
Trujillo-Villarreal, L. A., Cruz-Carrillo, G., Ángeles-Valdéz, D., Garza‐Villarreal, E. A., & Camacho‐Morales, A. (2024) · eNeuro · doi:10.1523/eneuro.0194-23.2023 · Cited by 4 · see citing works
Fronto‐Parietal and Cerebellar Circuits Characterize Individuals With Higher Trait Anxiety
Baggio, T., Grecucci, A., Crivello, F., Joliot, M., & Tzourio, C. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70210 · Cited by 3 · see citing works
Li, Q., Wang, W., & Hu, Z. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1091730 · Cited by 3 · see citing works
An amygdala-centered effective connectivity network in trait anxiety
Chang, J., Liu, X., Xue, S., & Qiu, J. (2023) · Brain Imaging and Behavior · doi:10.1007/s11682-023-00837-8 · Cited by 3 · see citing works
- Authors
- Baur, V., Hänggi, J., & Jäncke, L.
- Affiliations
- University of Zurich (CH)
- Corresponding author
- Baur, Volker
- Venue
- BMC Neuroscience
- Published
- 2012-01-04
- Volume
- 13
- Issue
- 1
- Pages
- 4-4
- ISSN
- 1471-2202 (ISSN-L)
- PMC
- PMC3398321
- OpenAlex
- W2158476113
- Cited by
- 121
- References
- 43
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 6 · 2023: 7 · 2022: 7 · 2021: 8 · 2020: 11 · 2019: 10 · 2018: 11 · 2017: 11 · 2016: 10 · 2015: 11 · 2014: 9 · 2013: 9 · 2012: 3
- FWCI
- 7.73
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Neuroscience (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Zurich Open Repository and Archive (University of Zurich)
- Funders
- Universität Zürich
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- uncinate fasciculus, amygdala, trait anxiety, white matter volume, structural connectivity, limbic system, anterior temporal lobe
- MeSH terms
- Adult, Amygdala, Anxiety Disorders, Brain Mapping, Female, Hippocampus, Humans, Functional Laterality, Male, Nerve Fibers, Myelinated, Neural Pathways, Psychometrics, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
