A diffusion tensor imaging tractography atlas for virtual in vivo dissections.
Abstract
Diffusion tensor imaging (DTI) tractography allows perform virtual dissections of white matter pathways in the living human brain. In 2002, Catani et al. published a method to reconstruct white matter pathways using a region of interest (ROI) approach. The method produced virtual representations of white matter tracts faithful to classical post-mortem descriptions but it required detailed a priori anatomical knowledge. Here, using the same approach, we provide a template to guide the delineation of ROIs for the reconstruction of the association, projection and commissural pathways of the living human brain. The template can be used for single case studies and case-control comparisons. An atlas of the 3D reconstructions of the single tracts is also provided as anatomical reference in the Montreal Neurological Institute (MNI) space.
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The consensus is that the IFOF connects the ventral occipital cortex with the inferior frontal and fronto-orbital cortices.
“the IFOF connects the ventral occipital cortex with the inferior frontal and fronto-orbital cortices”
From Cortical Terminations of the Inferior Fronto-Occipital and Uncinate Fasciculi: Anatomical Stem-Based Virtual Dissection (2016) · cites this paper as Catani and Thiebaut de Schotten, 2008
The consensus on the UF is that it connects, along with the fronto-orbital and temporo-polar cortices, ventral temporal areas.
“The consensus on the UF is that it connects, along with the fronto-orbital and temporo-polar cortices, ventral temporal areas (Ebeling and von Cramon, 1992; Catani and Thiebaut de Schotten, 2008).”
From Cortical Terminations of the Inferior Fronto-Occipital and Uncinate Fasciculi: Anatomical Stem-Based Virtual Dissection (2016) · cites this paper as Catani and Thiebaut de Schotten, 2008
The stem-based virtual dissection results in more extensive IFOFs and UFs than current set-of-ROIs methods.
“our stem-based virtual dissection results in more extensive IFOFs and UFs.”
From Cortical Terminations of the Inferior Fronto-Occipital and Uncinate Fasciculi: Anatomical Stem-Based Virtual Dissection (2016) · cites this paper as Catani and Thiebaut de Schotten, 2008
Projections to the parietal lobe are systematically excluded using the method of Zhang et al. (2010) and are likely to be missed using the method of Catani and Thiebaut de Schotten (2008), as was the case in Sarubbo et al. (2013).
“As shown Figure 8, projections to the parietal lobe are systematically excluded using the method of Zhang et al. (2010) and are likely to be missed using the method of Catani and Thiebaut de Schotten (2008) that use ROIs delineated around the frontal and occipital lobes, as was the case in Sarubbo et al. (2013).”
From Cortical Terminations of the Inferior Fronto-Occipital and Uncinate Fasciculi: Anatomical Stem-Based Virtual Dissection (2016) · cites this paper as Catani and Thiebaut de Schotten (2008)
Current tract segmentation approaches rely heavily on a priori knowledge, using set-of-ROIs strategies that place ROIs around known terminal areas or areas of passage.
“While current tract segmentation approaches rely heavily on a priori knowledge, using set-of-ROIs strategies that place the ROIs around their known terminal areas or areas of passage (Catani and Thiebaut de Schotten, 2008; Zhang et al., 2010)”
From Cortical Terminations of the Inferior Fronto-Occipital and Uncinate Fasciculi: Anatomical Stem-Based Virtual Dissection (2016) · cites this paper as Catani and Thiebaut de Schotten, 2008
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- Authors
- CATANI, M., & THIEBAUTDESCHOTTEN, M.
- Affiliations
- King's College London (GB)
- Corresponding author
- CATANI, M
- ORCID
- CATANI, M
- Venue
- Cortex
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 44
- Issue
- 8
- Pages
- 1105-1132
- ISSN
- 0010-9452 (ISSN-L)
- OpenAlex
- W2045498423
- Cited by
- 1,642
- References
- 2
- Citations by year
- 2026: 45 · 2025: 78 · 2024: 86 · 2023: 81 · 2022: 104 · 2021: 121 · 2020: 121 · 2019: 128 · 2018: 117 · 2017: 122 · 2016: 116 · 2015: 109 · 2014: 88 · 2013: 92 · 2012: 69
- FWCI
- 41.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cortex (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Anatomy › Medical and Biological Sciences
- Keywords
- diffusion tensor tractography, virtual dissection, white matter tracts, region of interest delineation, commissural pathways, MNI space
- MeSH terms
- Adult, Anatomy, Artistic, Atlases as Topic, Brain, Brain Mapping, Computer Simulation, Humans, Male, Medical Illustration, Nerve Fibers, Myelinated, Neural Conduction, Neural Pathways, Reference Values, Diffusion Magnetic Resonance Imaging
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