DSM-5: a collection of psychiatrist views on the changes, controversies, and future directions
Open accessAbstract
The recent release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by the American Psychiatric Association has led to much debate. For this forum article, we asked BMC Medicine Editorial Board members who are experts in the field of psychiatry to discuss their personal views on how the changes in DSM-5 might affect clinical practice in their specific areas of psychiatric medicine. This article discusses the influence the DSM-5 may have on the diagnosis and treatment of autism, trauma-related and stressor-related disorders, obsessive-compulsive and related disorders, mood disorders (including major depression and bipolar disorders), and schizophrenia spectrum disorders.
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The weaknesses of the ICD-11 and DSM-5 systems are debatable and unavoidable given the lack of any objective pathophysiological compass and the limited specificity of most currently available biomarkers in mental illness.
“The weaknesses of the two systems are both debatable and unavoidable [43, 44] given the lack of any objective pathophysiological compass and the limited specificity of most currently available biomarkers in mental illness [45].”
From Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies (2020) · cites this paper as [44]
The Introduction describes DSM-5 as controversial and says current psychiatric research lacks the tools for a major biologically grounded revision; it also reports that hoped-for diagnostic biomarkers have not materialized. The Autism section criticizes DSM-5’s failure to harmonize with ICD-11, but does not establish that ICD-11’s own weaknesses are unavoidable. In the citing sentence, the biomarker explanation is separately attributed to [45]. No page numbers are available in our copy. (LLM, conf=0.84)
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- Authors
- Nemeroff, C. B., Weinberger, D., Rutter, M., MacMillan, H. L., Bryant, R. A., Wessely, S., Stein, D. J., Pariante, C. M., Seemüller, F., Berk, M., Malhi, G. S., Preisig, M., Brüne, M., & Lysaker, P.
- Affiliations
- University of Miami (US)
- Johns Hopkins University (US)
- King's College London (GB)
- McMaster University (CA)
- UNSW Sydney (AU)
- University of Cape Town (ZA)
- Ludwig-Maximilians-Universität München (DE)
- Barwon Health (AU)
- The University of Sydney (AU)
- Centre Hospitalier Universitaire Vaudois (CH)
- University Hospitals of the Ruhr-University of Bochum (DE)
- Richard L. Roudebush VA Medical Center (US)
- ORCID
- Venue
- BMC Medicine
- Published
- 2013-09-12
- Volume
- 11
- Issue
- 1
- Pages
- 202-202
- ISSN
- 1741-7015 (ISSN-L)
- PMC
- PMC3846446
- OpenAlex
- W2032302431
- Cited by
- 128
- References
- 72
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 15 · 2023: 12 · 2022: 7 · 2021: 4 · 2020: 16 · 2019: 7 · 2018: 8 · 2017: 12 · 2016: 6 · 2015: 12 · 2014: 22 · 2013: 1
- FWCI
- 99.77
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Medicine (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- SERVAL (Université de Lausanne) (publishedVersion, other-oa)
- IUScholarWorks (Indiana University) (submittedVersion, cc-by)
- IRIS (submittedVersion)
- Research Portal (King's College London) (submittedVersion, other-oa)
- Open access LMU (Ludwid Maxmilian's Universitat Munchen) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- Open University of Cape Town (University of Cape Town) (submittedVersion, cc-by)
- Topics
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Psychology and Mental Health
- Keywords
- DSM-5, psychiatric diagnosis, diagnostic classification, autism spectrum disorder, obsessive-compulsive and related disorders, mood disorders, major depressive disorder, bipolar disorder, schizophrenia spectrum disorders, clinical practice, psychiatrists' perspectives
- MeSH terms
- Humans, Psychiatry, Diagnostic and Statistical Manual of Mental Disorders
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