Protocol for CHANGE: a randomized clinical trial assessing lifestyle coaching plus care coordination versus care coordination alone versus treatment as usual to reduce risks of cardiovascular disease in adults with schizophrenia and abdominal obesity
Open accessAbstract
BACKGROUND: Life expectancy in patients with schizophrenia is reduced by 20 years for males and 15 years for females compared to the general population. About 60% of the excess mortality is due to physical illnesses, with cardiovascular disease being the single largest cause of death. METHODS/DESIGN: The CHANGE trial is an investigator-initiated, independently funded, randomized, parallel-group, superiority, multi-centre trial with blinded outcome assessment. 450 patients aged 18 years or above, diagnosed with schizophrenia spectrum disorders and increased waist circumference, will be recruited and randomized 1:1:1 to 12-months interventions. We will compare the effects of 1) affiliation to the CHANGE team, offering a tailored, manual-based intervention targeting physical inactivity, unhealthy dietary habits, and smoking, and facilitating contact to their general practitioner to secure medical treatment of somatic comorbidity; versus 2) affiliation to a care coordinator who will secure guideline-concordant monitoring and treatment of somatic comorbidity by facilitating contact to their general practitioner; versus 3) treatment as usual to evaluate the potential add-on effects of lifestyle coaching plus care coordination or care coordination alone to treatment as usual. The primary outcome is the 10-year risks of cardiovascular disease assessed at 12 months after randomization. DISCUSSION: The premature mortality observed in this vulnerable population has not formerly been addressed specifically by using composite surrogate outcomes for mortality. The CHANGE trial expands the evidence for interventions aiming to reduce the burden of metabolic disturbances with a view to increase life expectancy. Here, we present the trial design, describe the methodological concepts in detail, and discuss the rationale and challenges of the intermediate outcomes. TRIAL REGISTRATION: Clinical Trials.gov NCT01585493 . Date of registration 27(th) of March 2012.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The trial protocol was published in 2015 with no changes made to the original version.
“The trial protocol was published in 2015 with no changes made to the original version 21 .”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
2 retracted
Assertive community treatment for people with severe mental disorders
Marshall, M., & Lockwood, A. (1998) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001089 · Cited by 589 · see citing works
RetractedAssertive community treatment for people with severe mental disorders
Marshall, M., & Lockwood, A. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001089.pub2 · Cited by 146 · see citing works
RetractedA Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807 · see citing works
The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire
HEATHERTON, T. F., KOZLOWSKI, L. T., FRECKER, R. C., & FAGERSTROM, K. (1991) · British Journal of Addiction · doi:10.1111/j.1360-0443.1991.tb01879.x · Cited by 10,738 · see citing works
Durnin, J. V. G. A., & Womersley, J. (1974) · British Journal Of Nutrition · doi:10.1079/bjn19740060 · Cited by 6,343 · see citing works
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials
Chan, A.-W., Tetzlaff, J. M., Gotzsche, P. C., Altman, D. G., Mann, H., Berlin, J. A., Dickersin, K., Hrobjartsson, A., Schulz, K. F., Parulekar, W. R., et al. (2013) · BMJ · doi:10.1136/bmj.e7586 · Cited by 6,251 · see citing works
The Danish Civil Registration System
Pedersen, C. (2011) · Scandinavian Journal of Public Health · doi:10.1177/1403494810387965 · Cited by 4,713 · see citing works
The Danish Civil Registration System as a tool in epidemiology
Schmidt, M., Pedersen, L., & Sørensen, H. T. (2014) · European Journal of Epidemiology · doi:10.1007/s10654-014-9930-3 · Cited by 3,446 · see citing works
Kodama, S. (2009) · JAMA · doi:10.1001/jama.2009.681 · Cited by 3,035 · see citing works
Moher, D., Schulz, K. F., & Altman, D. G. (2001) · BMC Medical Research Methodology · doi:10.1186/1471-2288-1-2 · Cited by 2,755 · see citing works
Review: a gentle introduction to imputation of missing values.
Donders, A. R. T., van der Heijden, G. J. M. G., Stijnen, T., & Moons, K. G. M. (2006) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2006.01.014 · Cited by 2,582 · see citing works
Wood, L., Egger, M., Gluud, L. L., Schulz, K. F., Jüni, P., Altman, D. G., Gluud, C., Martin, R. M., Wood, A. J. G., & Sterne, J. A. C. (2008) · BMJ · doi:10.1136/bmj.39465.451748.ad · Cited by 2,538 · see citing works
Self-citationDE HERT, M., CORRELL, C. U., BOBES, J., CETKOVICH‐BAKMAS, M., COHEN, D., ASAI, I., DETRAUX, J., GAUTAM, S., MÖLLER, H., NDETEI, D. M., et al. (2011) · World Psychiatry · doi:10.1002/j.2051-5545.2011.tb00014.x · Cited by 2,488 · see citing works
De Backer, G. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)00347-6 · Cited by 2,251 · see citing works
Self-rated health: a predictor of mortality among the elderly.
Mossey, J. M., & Shapiro, E. (1982) · American Journal of Public Health · doi:10.2105/ajph.72.8.800 · Cited by 2,145 · see citing works
Saha, S., Chant, D., & McGrath, J. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.10.1123 · Cited by 2,065 · see citing works
Industry sponsorship and research outcome
Lundh, A., Lexchin, J., Mintzes, B., Schroll, J. B., & Bero, L. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.mr000033.pub3 · Cited by 1,697 · see citing works
The Danish Psychiatric Central Research Register
Mors, O., Perto, G. P., & Mortensen, P. B. (2011) · Scandinavian Journal of Public Health · doi:10.1177/1403494810395825 · Cited by 1,589 · see citing works
Self-citationKeefe, R. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2003.09.011 · Cited by 1,573 · see citing works
(1992) · PubMed · Cited by 1,429 · see citing works
de Leon, J., & Diaz, F. J. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.02.010 · Cited by 1,276 · see citing works
Metabolic Syndrome and Risk of Cardiovascular Disease: A Meta-Analysis
Galassi, A., Reynolds, K., & He, J. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2006.02.031 · Cited by 1,205 · see citing works
De Hert, M., Dekker, J. M., Wood, D., Kahl, K. G., Holt, R. I. G., & Möller, H.-J. (2009) · European Psychiatry · doi:10.1016/j.eurpsy.2009.01.005 · Cited by 951 · see citing works
The Danish National Health Service Register
Andersen, J. S., Olivarius, N. D. F., & Krasnik, A. (2011) · Scandinavian Journal of Public Health · doi:10.1177/1403494810394718 · Cited by 892 · see citing works
Lawrence, D., Hancock, K. J., & Kisely, S. (2013) · BMJ · doi:10.1136/bmj.f2539 · Cited by 819 · see citing works
Nordentoft, M., Wahlbeck, K., Hällgren, J., Westman, J., Ösby, U., Alinaghizadeh, H., Gissler, M., & Laursen, T. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055176 · Cited by 778 · see citing works
Self-citationSavović, J., Jones, H., Altman, D., Harris, R., Jűni, P., Pildal, J., Als-Nielsen, B., Balk, E., Gluud, C., Gluud, L., et al. (2012) · Health Technology Assessment · doi:10.3310/hta16350 · Cited by 668 · see citing works
Self-citationMetabolic syndrome in people with schizophrenia: a review
DE HERT, M., SCHREURS, V., VANCAMPFORT, D., & VAN WINKEL, R. (2009) · World Psychiatry · doi:10.1002/j.2051-5545.2009.tb00199.x · Cited by 634 · see citing works
Industry sponsorship and research outcome
Lundh, A., Sismondo, S., Lexchin, J., Busuioc, O. A., & Bero, L. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.mr000033.pub2 · Cited by 605 · see citing works
Multiple risk factor interventions for primary prevention of coronary heart disease
Ebrahim, S. B. J., Taylor, F. C., Ward, K. J., Beswick, A. D., Burke, M., & Smith, G. D. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001561.pub3 · Cited by 546 · see citing works
A Behavioral Weight-Loss Intervention in Persons with Serious Mental Illness
Daumit, G. L., Dickerson, F. B., Wang, N.-Y., Dalcin, A., Jerome, G. J., Anderson, C. A. M., Young, D. R., Frick, K. D., Yu, A., Gennusa, J. V., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1214530 · Cited by 523 · cited 1× · see citing works
“1 kg/m(2) between patients in the intervention group and controls [29].”
BackgroundBacker, G. D., Ambrosioni, E., Borch‐Johnsen, K., Brotons, C., Cífková, R., Dallongeville, J., Ebrahim, S. B. J., Færgeman, O., Graham, I. D., Mancia, G., et al. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.02.013 · Cited by 508 · see citing works
Andreassen, O. A., Djurovic, S., Thompson, W. K., Schork, A. J., Kendler, K. S., O’Donovan, M. C., Rujescu, D., Werge, T., van de Bunt, M., Morris, A. P., et al. (2013) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2013.01.001 · Cited by 506 · see citing works
Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials
Pildal, J., Hrobjartsson, A., Jorgensen, K., Hilden, J., Altman, D., & Gotzsche, P. (2007) · International Journal of Epidemiology · doi:10.1093/ije/dym087 · Cited by 472 · see citing works
Generalizability studies of the Global Assessment of Functioning–Split version
Pedersen, G., Hagtvet, K. A., & Karterud, S. (2006) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2006.03.008 · Cited by 446 · see citing works
Jørgensen, T., Borch‐Johnsen, K., Thomsen, T. F., Ibsen, H., Glümer, C., & Pisinger, C. H. (2003) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/01.hjr.0000096541.30533.82 · Cited by 416 · see citing works
Self-citationThe Danish registers of causes of death.
Juel, K., & Helweg‐Larsen, K. (1999) · PubMed · Cited by 410 · see citing works
The dietary pattern of patients with schizophrenia: A systematic review
Dipasquale, S., Pariante, C. M., Dazzan, P., Aguglia, E., McGuire, P. K., & Mondelli, V. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.10.005 · Cited by 399 · see citing works
Lewandowsky, S. (2015) · Bristol Research (University of Bristol) · doi:10.5523/bris.swyt56qr4vaj17op9cw3sag7d · Cited by 369 · see citing works
Wu, R.-R., Zhao, J.-P., Jin, H., Shao, P., Fang, M.-S., Guo, X.-F., He, Y.-Q., Liu, Y.-J., Chen, J.-D., & Li, L.-H. (2008) · JAMA · doi:10.1001/jama.2007.56-b · Cited by 366 · see citing works
Interventions for smoking cessation and reduction in individuals with schizophrenia
Tsoi, D. T., Porwal, M., & Webster, A. C. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007253.pub3 · Cited by 304 · see citing works
Jørgensen, T., Jacobsen, R. K., Toft, U., Aadahl, M., Glümer, C., & Pisinger, C. H. (2014) · BMJ · doi:10.1136/bmj.g3617 · Cited by 296 · see citing works
Self-citationMethods for Assessing Positive and Negative Symptoms1
Andreasen, N. C. (2015) · Modern problems of pharmacopsychiatry/Modern trends in pharmacopsychiatry · doi:10.1159/000418013 · Cited by 282 · see citing works
for the CONSORT Group*, Moher, D., Schulz, K. F., & Altman, D. G. (2003) · Clinical Oral Investigations · doi:10.1007/s00784-002-0188-x · Cited by 259 · see citing works
Exercise therapy improves mental and physical health in schizophrenia: a randomised controlled trial
Scheewe, T. W., Backx, F. J. G., Takken, T., Jörg, F., van Strater, A. C. P., Kroes, A. G., Kahn, R. S., & Cahn, W. (2013) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12029 · Cited by 246 · see citing works
Smıth, D. J., Langan, J., McLean, G., Guthrie, B., & Mercer, S. W. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-002808 · Cited by 244 · see citing works
Daumit, G. L., Goff, D. C., Meyer, J. M., Davis, V. G., Nasrallah, H. A., McEvoy, J. P., Rosenheck, R., Davis, S. M., Hsiao, J. K., Stroup, T. S., et al. (2008) · Schizophrenia Research · doi:10.1016/j.schres.2008.07.006 · Cited by 223 · see citing works
Björkman, T., & Svensson, B. (2005) · Nordic Journal of Psychiatry · doi:10.1080/08039480500213733 · Cited by 216 · see citing works
McKibbin, C., Patterson, T., Norman, G., Patrick, K., Jin, H., Roesch, S. C., Mudaliar, S., Barrio, C., O'Hanlon, K. M., Griver, K., et al. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.05.010 · Cited by 216 · see citing works
Evins, A. E., Cather, C., Pratt, S. A., Pachas, G. N., Hoeppner, S. S., Goff, D. C., Achtyes, E. D., Ayer, D., & Schoenfeld, D. A. (2014) · JAMA · doi:10.1001/jama.2013.285113 · Cited by 207 · see citing works
Toft, U., Kristoffersen, L., Lau, C. J., Borch‐Johnsen, K., & Jørgensen, T. (2006) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602503 · Cited by 202 · see citing works
Jakobsen, J. C., Gluud, C. N., Winkel, P., Lange, T., & Wetterslev, J. (2014) · BMC Medical Research Methodology · doi:10.1186/1471-2288-14-34 · Cited by 201 · see citing works
Self-citationThe Effects of an Educational Intervention on Antipsychotic‐Induced Weight Gain
Littrell, K. H., Hilligoss, N. M., Kirshner, C. D., Petty, R. G., & Johnson, C. G. (2003) · Journal of Nursing Scholarship · doi:10.1111/j.1547-5069.2003.00237.x · Cited by 190 · see citing works
Caemmerer, J., Correll, C. U., & Maayan, L. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.03.017 · Cited by 182 · see citing works
Brar, J. S., Ganguli, R., Pandina, G., Turkoz, I., Berry, S., & Mahmoud, R. A. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0208 · Cited by 178 · see citing works
Williams, J. M., Anthenelli, R. M., Morris, C. D., Treadow, J., Thompson, J. R., Yunis, C., & George, T. P. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.11m07522 · Cited by 162 · see citing works
Bonfioli, E., Berti, L., Goss, C., Muraro, F., & Burti, L. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-78 · Cited by 154 · see citing works
A maximal cycle exercise protocol to predict maximal oxygen uptake
Andersen, L. B. (1995) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.1995.tb00027.x · Cited by 151 · see citing works
Kwon, J. S., Choi, J., Bahk, W.-M., Kim, C. Y., Kim, C. H., Shin, Y. C., Park, B., & Oh, C. G. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n0405 · Cited by 150 · see citing works
Scheewe, T. W., van Haren, N. E. M., Sarkisyan, G., Schnack, H. G., Brouwer, R. M., de Glint, M., Hulshoff Pol, H. E., Backx, F. J. G., Kahn, R. S., & Cahn, W. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.08.008 · Cited by 148 · see citing works
Hepatology may have problems with putative surrogate outcome measures.
Gluud, C., Brok, J., Gong, Y., & Koretz, R. (2007) · Journal of Hepatology · doi:10.1016/j.jhep.2007.01.003 · Cited by 143 · see citing works
Self-citationAbdominal Obesity and Cardiovascular Disease: Is Inflammation the Missing Link?
Després, J. (2012) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2012.06.004 · Cited by 133 · see citing works
Thomsen, T. F., Davidsen, M., Ibsen, H., Jorgensen, T., Jensen, G., & Borch-Johnsen, K. (2001) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1177/174182670100800508 · Cited by 127 · see citing works
Construct validity of a revised Physical Activity Scale and testing by cognitive interviewing
Bjerregaard, L. G., Grøenvold, M., Jørgensen, T., & Aadahl, M. (2010) · Scandinavian Journal of Public Health · doi:10.1177/1403494810380099 · Cited by 108 · see citing works
Industry Sponsorship and Research Outcome
Bero, L. A. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.4190 · Cited by 104 · see citing works
Diagnosis and clinical measurement in psychiatry : a reference manual for SCAN
Wing, J. K., Sartorius, N., & Üstün, T. B. (2008) · Cited by 103 · see citing works
Graeber, D. A., Moyers, T. B., Griffith, G., Guajardo, E., & Tonigan, S. (2003) · Community Mental Health Journal · doi:10.1023/a:1023371705506 · Cited by 103 · see citing works
Laursen, T. M., & Nordentoft, M. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.04.027 · Cited by 93 · see citing works
Self-citationAn experimental study on variability of measurements of skinfold thickness on young adults.
Womersley, J., & Durnin, J. V. G. A. (1973) · PubMed · Cited by 91 · see citing works
Methapatara, W., & Srisurapanont, M. (2011) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2011.02225.x · Cited by 84 · see citing works
The Necessity of Randomized Clinical Trials
Jakobsen, J. C. (2013) · Journal of Advances in Medicine and Medical Research · doi:10.9734/bjmmr/2013/3208 · Cited by 84 · see citing works
Siersma, V., Als-Nielsen, B. E. T., Chen, W., Hilden, J., Gluud, L. L., & Gluud, C. N. (2006) · Statistics in Medicine · doi:10.1002/sim.2752 · Cited by 83 · see citing works
Self-citationJanney, C. A., Ganguli, R., Richardson, C. R., Holleman, R. G., Tang, G., Cauley, J. A., & Kriska, A. M. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.01.010 · Cited by 79 · see citing works
Laursen, T. M., Mortensen, P. B., MacCabe, J. H., Cohen, D., & Gasse, C. (2013) · Psychological Medicine · doi:10.1017/s003329171300216x · Cited by 78 · see citing works
Winkel, P., Hilden, J., Hansen, J. F., Kastrup, J., Kolmos, H. J., Kjøller, E., Jensen, G. B., Skoog, M., Lindschou, J., & Gluud, C. N. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.01.020 · Cited by 75 · see citing works
Self-citationAttux, C. R. D. F., Martini, L. C., Elkis, H., Tamai, S., Freirias, A., Camargo, M. D. G. M., Mateus, M. D., Mari, J. D. J., Reis, A. F., & Bressan, R. A. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-60 · Cited by 75 · see citing works
Jørgensen, A. W., Lundstrøm, L. H., Wetterslev, J., Astrup, A., & Gøtzsche, P. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111964 · Cited by 40 · see citing works
Rowland, B., Toumbourou, J. W., Osborn, A., Smith, R., Hall, J. K., Kremer, P. J., Kelly, A. B., Williams, J. W., & Leslie, E. R. (2013) · BMJ Open · doi:10.1136/bmjopen-2012-002423 · Cited by 39 · see citing works
Can Exercise Increase Fitness and Reduce Weight in Patients with Schizophrenia and Depression?
Krogh, J., Speyer, H., Nørgaard, H. C. B., Moltke, A., & Nordentoft, M. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00089 · Cited by 34 · see citing works
Self-citationKilbourne, A., Bramlet, M., Barbaresso, M. M., Nord, K. M., Goodrich, D. E., Lai, Z.-S., Post, E., Almirall, D., Verchinina, L., Duffy, S., et al. (2014) · Contemporary Clinical Trials · doi:10.1016/j.cct.2014.07.007 · Cited by 28 · see citing works
Nordentoft, M., Pedersen, M. G., Pedersen, C. B., Blinkenberg, S., & Mortensen, P. B. (2011) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-011-0432-2 · Cited by 27 · see citing works
Self-citationAssociations Between Metabolic and Aerobic Fitness Parameters in Patients With Schizophrenia
Vancampfort, D., Guelinkcx, H., Probst, M., Stubbs, B., Rosenbaum, S., Ward, P. B., & Binder, M. D. (2014) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000229 · Cited by 19 · see citing works
Fysisk aktivitet bør tilbys som behandling
(2011) · Sykepleien Forskning · doi:10.4220/sykepleienf.2011.0196 · Cited by 1 · see citing works
Flagged first, then by citations
2 of the 86 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Speyer, H., Christian Brix Nørgaard, H., Birk, M., Karlsen, M., Storch Jakobsen, A., Pedersen, K., Hjorthøj, C., Pisinger, C., Gluud, C., Mors, O., et al. (2016) · World Psychiatry · doi:10.1002/wps.20318 · Cited by 153 · see citing works
Self-citationJakobsen, A. S., Speyer, H., Nørgaard, H. C. B., Karlsen, M., Hjorthøj, C. R., Krogh, J., Mors, O. N., Nordentoft, M., & Toft, U. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.03.016 · Cited by 92 · see citing works
Self-citationBradley, T., Campbell, E., Dray, J., Bartlem, K., Wye, P., Hanly, G., Gibson, L., Fehily, C., Bailey, J., Wynne, O., et al. (2022) · Systematic Reviews · doi:10.1186/s13643-022-02067-3 · Cited by 70 · see citing works
Rosa, C. D., Sampogna, G., Luciano, M., Vecchio, V. D., Pocai, B., Borriello, G., Giallonardo, V., Savorani, M., Pinna, F., Pompili, M., et al. (2017) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2017.1325321 · Cited by 68 · see citing works
Jakobsen, A. S., Speyer, H., Nørgaard, H. C. B., Karlsen, M., Birk, M., Hjorthøj, C. R., Mors, O. N., Krogh, J., Gluud, C. N., Pisinger, C. H., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0185881 · Cited by 61 · see citing works
Self-citationJakobsen, A. S., Speyer, H., Nørgaard, H. C. B., Hjorthøj, C. R., Krogh, J., Mors, O. N., & Nordentoft, M. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.02.047 · Cited by 58 · see citing works
Self-citationon behalf of the IMPaCT Team, Gaughran, F., Stahl, D. R., Ismail, K., Greenwood, K., Atakan, Z., Gardner-Sood, P., Stubbs, B., Hopkins, D., Patel, A. K., et al. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1571-0 · Cited by 46 · see citing works
Sampogna, G., Fiorillo, A., Luciano, M., Vecchio, V. D., Steardo, L., Pocai, B., Barone, M., Amore, M., Pacitti, F., Dell’Osso, L., et al. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00235 · Cited by 36 · see citing works
Luciano, M., Sampogna, G., Amore, M., Andriola, I., Calcagno, P., Carmassi, C., Vecchio, V. D., Dell’Osso, L., Lorenzo, G. D., Gelao, B., et al. (2021) · European Psychiatry · doi:10.1192/j.eurpsy.2021.2253 · Cited by 25 · see citing works
Luciano, M., Sampogna, G., D’Ambrosio, E., Rampino, A., Amore, M., Calcagno, P., Rossi, A., Rossi, R., Carmassi, C., Dell’Osso, L., et al. (2023) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-023-01684-w · Cited by 25 · see citing works
Strunz, M., Jiménez, N. P., Gregorius, L., Hewer, W., Pollmanns, J., Viehmann, K., & Jacobi, F. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20010126 · Cited by 19 · see citing works
Staunstrup, N. H., Starnawska, A., Nyegaard, M., Nielsen, A. L., Børglum, A. D., & Mors, O. N. (2017) · Epigenomes · doi:10.3390/epigenomes1030014 · Cited by 10 · see citing works
Self-citationSøgaard, H. J., Højlund, M., Elliott, A. F., Viuff, A. G., Vandborg, K., Viuff, J. H., Munk‐Jørgensen, P., & Hjorth, P. (2018) · American Journal of Therapeutics · doi:10.1097/mjt.0000000000000708 · Cited by 5 · see citing works
Management of Common Medical Conditions by Office-Based Psychiatrists
Mojtabai, R., & Olfson, M. (2017) · Psychiatric Services · doi:10.1176/appi.ps.201700255 · Cited by 4 · see citing works
Marano, G., Marzo, E. M., Sfratta, G., Traversi, G., Capristo, E., Gaetani, E., & Mazza, M. (2026) · Life · doi:10.3390/life16010146 · Cited by 3 · see citing works
Stanislaus, S., Speyer, H., Forman, J. L., Nordentoft, M., Poulsen, H. E., Kessing, L. V., Vinberg, M., & Coello, K. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.10.258 · Cited by 1 · see citing works
Self-citationCardiovascular Risk and Metabolic Syndrome in Individuals with Mental Disorders
Cabral, S. D. M. R., & dos Santos, M. M. (2019) · International Journal of Cardiovascular Sciences · doi:10.5935/2359-4802.20190027
The Management of Comorbidities: The Role of Psychosocial Interventions
Sampogna, G., Vincenzo, M. D., Catapano, P., Luciano, M., & Fiorillo, A. (2025) · Springer eBooks · doi:10.1007/978-3-031-81802-8_19
Bradley, T., Campbell, E. M., Dray, J., Bartlem, K. M., Wye, P. M., Hanly, G., Gibson, L., Fehily, C. M. C., Bailey, J. M., Wynne, O., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21077388
Najar, H., Jedenius, E., Fröberg, A., Olofsson, A., Holmbom, C., Björlin, C. K., Hagberg, C., Saari-Bladmyr, E., Hantelius, E., Wålinder, E., et al. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-08315-3
- Authors
- Speyer, H., Nørgaard, H. C. B., Hjorthøj, C., Madsen, T. A., Drivsholm, S., Pisinger, C., Gluud, C., Mors, O., Krogh, J., & Nordentoft, M.
- Affiliations
- University of Copenhagen (DK)
- Aarhus University Hospital (DK)
- Mental Health Services (DK)
- Glostrup Hospital (DK)
- Copenhagen University Hospital (DK)
- Corresponding author
- Speyer, Helene
- ORCID
- Venue
- BMC Psychiatry
- Published
- 2015-05-23
- Volume
- 15
- Issue
- 1
- Pages
- 119-119
- ISSN
- 1471-244X (ISSN-L)
- PMC
- PMC4460642
- OpenAlex
- W1946483406
- Cited by
- 20
- References
- 86
- Citations by year
- 2026: 2 · 2025: 2 · 2023: 1 · 2022: 3 · 2021: 1 · 2019: 1 · 2018: 4 · 2017: 5 · 2016: 1
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Psychiatry (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, cc-by)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Funders
- Lundbeckfonden (R155-2014-1724, R108-2012-10620)
- Region Hovedstaden
- TrygFonden
- H. Lundbeck A/S
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- schizophrenia, abdominal obesity, cardiovascular risk, lifestyle coaching, care coordination, somatic comorbidity, physical inactivity, dietary habits, smoking, premature mortality, life expectancy, waist circumference, metabolic disorders, general practitioner contact
- MeSH terms
- Cardiovascular Diseases, Clinical Protocols, Counseling, Female, Humans, Life Style, Male, Middle Aged, Schizophrenia, Obesity, Abdominal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review