Chat- and internet-based cognitive–behavioural therapy in treatment of adolescent depression: randomised controlled trial

Topooco, Naira; Berg, Matilda; Johansson, Sofie; Liljethörn, Lina; Radvogin, Ella; Vlaescu, George; Nordgren, Lise Bergman; Zetterqvist, Maria; Andersson, Gerhard

doi:10.1192/bjo.2018.18

Cited by 90Digital Mental Health InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and Access

Chat- and internet-based cognitive–behavioural therapy in treatment of adolescent depression: randomised controlled trial

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Topooco, Naira, Berg, Matilda, Johansson, Sofie, Liljethörn, Lina, Radvogin, Ella, Vlaescu, George, Nordgren, Lise Bergman, Zetterqvist, Maria +1 more·2018·BJPsych Open

DOI 10.1192/bjo.2018.18PMC PMC6034465

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Abstract

Background: Depression is a major contributor to the burden of disease in the adolescent population. Internet-based interventions can increase access to treatment. Aims: To evaluate the efficacy of internet-based cognitive–behavioural therapy (iCBT), including therapist chat communication, in treatment of adolescent depression. Method: Seventy adolescents, 15–19 years of age and presenting with depressive symptoms, were randomised to iCBT or attention control. The primary outcome was the Beck Depression Inventory II (BDI-II). Results: Significant reductions in depressive symptoms were found, favouring iCBT over the control condition (F(1,67) = 6.18, P < 0.05). The between-group effect size was Cohen's d = 0.71 (95% CI 0.22–1.19). A significantly higher proportion of iCBT participants (42.4%) than controls (13.5%) showed a 50% decrease in BDI-II score post-treatment (P < 0.01). The improvement for the iCBT group was maintained at 6 months. Conclusions: The intervention appears to effectively reduce symptoms of depression in adolescents and may be helpful in overcoming barriers to care among young people. Declaration of interest: N.T. and G.A. designed the programme. N.T. authored the treatment material. The web platform used for treatment is owned by Linköping University and run on a non-for-profit basis. None of the authors receives any income from the programme.

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Studies of ICBT targeting adolescent populations have produced treatment effects and adherence similar to those of adult populations.
“and studies of ICBT targeting adolescent populations have produced treatment effects and adherence similar to those of adult populations (Berg et al., 2020b; Topooco et al., 2018).”
From Investigating the potential of a novel internet-based cognitive behavioural intervention for Dari and Farsi speaking refugee youth: A feasibility study (2022) · cites this paper as Topooco et al., 2018
The Results report a significant treatment effect for adolescent depression and 70% full treatment completion (Outcome measures; Programme use and treatment acceptability, pages not provided). The Discussion compares deterioration rates with an adult study, but our copy does not establish that treatment effects and adherence were similar to those in adult populations. (LLM, conf=0.85)
Experimental — accuracy not yet measured
The blended care delivery model used in this study could have provided a sense of connectedness with the research team for the participants.
“The blended care delivery model used in this study, although simple, promoting knowledge that the research team is only one phone call or text message away, could also have provided a sense of connectedness with the research team for the participants [62,63].”
From Short-Term Findings From Testing EPIO, a Digital Self-Management Program for People Living With Chronic Pain: Randomized Controlled Trial (2023) · cites this paper as [63]
Previous studies on adolescents have had a large majority of female participants.
“whereas previous studies on adolescents have had a large majority of female participants (Berg et al., 2020a; Topooco et al., 2018).”
From Investigating the potential of a novel internet-based cognitive behavioural intervention for Dari and Farsi speaking refugee youth: A feasibility study (2022) · cites this paper as Topooco et al., 2018
This novel kind of "blended" iCBT has been evaluated in several randomized controlled trials, showing highly promising results.
“This novel kind of “blended” iCBT has been evaluated in several randomized controlled trials, showing highly promising results (Lindqvist et al., 2020; Topooco et al., 2018; Topooco et al., 2019).”
From Transitioning from face-to-face treatment to iCBT for youths in primary care – therapists' attitudes and experiences (2020) · cites this paper as Topooco et al., 2018

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Additional file 1 of Behavioral Activation as an ‘active ingredient’ of interventions addressing depression and anxiety among young people: a systematic review and evidence synthesis
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Additional file 1 of Self-esteem in new light: a qualitative study of experiences of internet-based cognitive behaviour therapy for low self-esteem in adolescents
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Additional file 4 of Behavioral Activation as an ‘active ingredient’ of interventions addressing depression and anxiety among young people: a systematic review and evidence synthesis
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Authors: Topooco, N., Berg, M., Johansson, S., Liljethörn, L., Radvogin, E., Vlaescu, G., Nordgren, L. B., Zetterqvist, M., & Andersson, G.
Affiliations: Linköping University (SE)
Corresponding author: Topooco, Naira
ORCID: Topooco, Naira
Berg, Matilda
Vlaescu, George
Nordgren, Lise Bergman
Zetterqvist, Maria
Andersson, Gerhard
Venue: BJPsych Open
Publisher: Royal College of Psychiatrists
Published: 2018-06-26
Volume: 4
Issue: 4
Pages: 199-207
ISSN: 2056-4724 (ISSN-L)
DOI: 10.1192/bjo.2018.18
PMC: PMC6034465
OpenAlex: W2811455797
Cited by: 90
References: 51
Citations by year: 2026: 5 · 2025: 5 · 2024: 15 · 2023: 11 · 2022: 17 · 2021: 18 · 2020: 14 · 2019: 4 · 2018: 1
FWCI: 11.67
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (unspecified)
Locations: BJPsych Open (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
KTH Publication Database DiVA (KTH Royal Institute of Technology) (submittedVersion, other-oa)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders: Karolinska Institutet
Topics: Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords: adolescent depression, internet-based cognitive behavioral therapy, digital mental health interventions, depressive symptoms, barriers to care, treatment efficacy, maintenance of treatment effects

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Chat- and internet-based cognitive–behavioural therapy in treatment of adolescent depression: randomised controlled trial

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About these checks