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Cited by 455

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

London–East Anglia randomised controlled trial of cognitive–behavioural therapy for psychosis: I: Effects of the treatment phase

Kuipers, Elizabeth, Garety, Philippa, Fowler, David, Dunn, Graham, Bebbington, Paul, Freeman, Daniel, Hadley, Clare·1997·British Journal of Psychiatry

Abstract

Background: A series of small, mainly uncontrolled, studies have suggested that techniques adapted from cognitive–behavioural therapy (CBT) for depression can improve outcome in psychosis, but no large randomised controlled trial of intensive treatment for medication-resistant symptoms of psychosis has previously been published. Method: Sixty participants who each had at least one positive and distressing symptom of psychosis that was medication-resistant were randomly allocated between a CBT and standard care condition (n=28) and a standard care only control condition (n=32). Therapy was individualised, and lasted for nine months. Multiple assessments of outcome were used. Results: Over nine months, improvement was significant only in the treatment group, who showed a 25% reduction on the BPRS. No other clinical, symptomatic or functioning measure changed significantly. Participants had a low drop-out rate from therapy (11%), and expressed high levels of satisfaction with treatment (80%). Fifty per cent of the CBT group were treatment responders (one person became worse), compared with 31% of the control group (three people became worse and another committed suicide) Conclusions: CBT for psychosis can improve overall symptomatology. The findings provide evidence that even a refractory group of clients with a long history of psychosis can engage in talking about psychotic symptoms and their meaning, and this can improve outcome.

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Research works printed but not linked: 39

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Cited by

Metadata

Authors
Kuipers, E., Garety, P., Fowler, D., Dunn, G., Bebbington, P., Freeman, D., & Hadley, C.
Venue
British Journal of Psychiatry
Published
1997-10
Volume
171
Issue
4
Pages
319-327
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
OpenAlex
W2135077565
Cited by
455
References
5
FWCI
17.95
Type
journal article
Language
en
Open access
closed

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