Intestinal transport and metabolism of bile acids

Diet rapidly and reproducibly alters the human gut microbiome

David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V., Devlin, A. S., Varma, Y., Fischbach, M. A., et al. (2014) · Nature · doi:10.1038/nature12820 · Cited by 10,100

Host-gut microbiota metabolic interactions

Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S. (2012) · Science · doi:10.1126/science.1223813 · Cited by 4,760

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, J., Duncan, A. E., Kau, A. L., Griffin, N. W., Lombard, V., Henrissat, B., Bain, J. R., et al. (2013) · Science · doi:10.1126/science.1241214 · Cited by 3,788

Bile salt biotransformations by human intestinal bacteria

Ridlon, J. M., Kang, D.-J., & Hylemon, P. B. (2006) · Journal of Lipid Research · doi:10.1194/jlr.r500013-jlr200 · Cited by 2,829

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

Sayin, S. I., Wahlström, A., Felin, J., Jäntti, S., Marschall, H.-U., Bamberg, K., Angelin, B., Hyötyläinen, T., Orešič, M., & Bäckhed, F. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.01.003 · Cited by 2,331

The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

Russell, D. W. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161712 · Cited by 2,069

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice

Devkota, S., Wang, Y., Musch, M. W., Leone, V., Fehlner-Peach, H., Nadimpalli, A., Antonopoulos, D. A., Jabri, B., & Chang, E. B. (2012) · Nature · doi:10.1038/nature11225 · Cited by 1,904

The interaction between bacteria and bile

Begley, M., Gahan, C. G. M., & Hill, C. (2004) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2004.09.003 · Cited by 1,776

The microbiome and cancer

Schwabe, R. F., & Jobin, C. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3610 · Cited by 1,689

Bile Acid Metabolism and Signaling

Chiang, J. Y. L. (2013) · Comprehensive physiology · doi:10.1002/cphy.c120023 · Cited by 1,662

Urinary Bile Acid Profile of Newborns Born by Cesarean Section Is Characterized by Oxidative Metabolism of Primary Bile Acids: Limited Roles of Fetal-Specific CYP3A7 in Cholate Oxidations

Wang, W.-X., Chen, L., Wang, G.-Y., Zhang, J.-L., Tan, X.-W., Lin, Q.-H., Chen, Y.-J., Zhang, J., Zhu, P.-P., Miao, J., et al. (2020) · Drug Metabolism and Disposition · doi:10.1124/dmd.120.000011 · Cited by 7

Toxic bile and sclerosing cholangitis: Is there a role for pharmacological interruption of the bile acid enterohepatic circulation?

Dawson, P. A. (2015) · Hepatology · doi:10.1002/hep.28363 · Cited by 7

Beyond ADME: The Endogenous Functions of Drug Transporters and Its Impact on Human Disease

Blaze, C., & Shu, Y. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17060685 · Cited by 6

Antibiotic-induced gut microbiota depletion enhances glucose tolerance linked to GLP-1 signaling

Kellenberger, A., Dewal, R. S., d’Oplinter, A. D. W., Sichert, A., Heine, M., Fuh, M. M., Slack, E. M. C., Challa, T. D., & Wolfrum, C. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1684155 · Cited by 6

An Update on Role of Bile Acids in Neurological Functions and Neurodegenerative Diseases: A Narrative Review

Kaur, K. K., Allahbadia, G., & Singh, M. (2023) · Journal of Clinical and Biomedical Investigation · doi:10.52916/jcbi234026 · Cited by 6

The effects of chicken hydrolyzed proteins in extruded diets on plasma and fecal metabolic profiles in adult dogs

Hsu, C., Marx, F. R., Guldenpfennig, R., & de Godoy, M. R. C. (2024) · Scientific Reports · doi:10.1038/s41598-024-80176-w · Cited by 6

Vegetable oil intake:The distinctive trilateral relationship of bile acid, gut microbiota and health

Lin, X., Wu, J., & Li, Z. (2025) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2025.105001 · Cited by 6

Impact of Blueberry Consumption on the Human Fecal Bileacidome: A Pilot Study of Bile Acid Modulation by Freeze-Dried Blueberry

Gagnon, W., Garneau, V., Trottier, J., Verreault, M., Couillard, C., Roy, D., Marette, A., Drouin‐Chartier, J., Vohl, M., & Barbier, O. (2022) · Nutrients · doi:10.3390/nu14183857 · Cited by 6

Hepatic bile acid accretion correlates with cholestatic liver injury and therapeutic response in Cyp2c70 knockout mice with a humanized bile acid composition

Klindt, C., Truong, J. K., Bennett, A. L., Pachura, K. J., Herebıan, D., Mayatepek, E., Luedde, T., Ebert, M. P. A., Karpen, S. J., & Dawson, P. A. (2024) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00129.2024 · Cited by 7

Farnesoid X Receptor-Mediated Bile Acids Regulation in Cholestasis

Mohammed, T. A., & Zalzala, M. H. (2024) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-024-01292-y · Cited by 6

Pleurotus eryngii Mushrooms Fermented with Human Fecal Microbiota Protect Intestinal Barrier Integrity: Immune Modulation and Signalling Pathways Counter Deoxycholic Acid-Induced Disruption in Healthy Colonic Tissue

Kerezoudi, E. N., Zervakis, G. I., Pletsa, V., Kyriacou, A., Brummer, R. J., & Rangel, I. (2025) · Nutrients · doi:10.3390/nu17040694 · Cited by 6

Effects of a Western Diet on Colonic Dysbiosis, Bile Acid Dysmetabolism and Intestinal Inflammation in Clinically Healthy Dogs

Mason, B., Sahoo, D. K., Iennarella‐Servantez, C. A., Kathrani, A., Morgan, S., Bourgois‐Mochel, A., Bray, A. M., Gabriel, V., Zdyrski, C., Groeltz-Thrush, J. M., et al. (2025) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.70035 · Cited by 6

Physiology of Cholngiocytes

Masyuk, A. I., Masyuk, T. V., & LaRusso, N. F. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809954-4.00044-x · Cited by 6

Effects of genotype and food on naltrexone exposure in adolescents

Stancil, S. L., Voss, M. M., Nolte, W. M., Tumberger, J., Adelman, W. P., & Abdel‐Rahman, S. M. (2022) · Clinical and Translational Science · doi:10.1111/cts.13399 · Cited by 6

Clostridium scindens exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter

Calton, C. M., Carothers, K. E., Ramamurthy, S., Jagadish, N., Phanindra, B., Garcia, A., Viswanathan, V. K., & Halpern, M. D. (2023) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00102.2023 · Cited by 6

Metabolism of obeticholic acid in brown bullhead (Ameiurus nebulosus)

Mach, S., Jegorov, A., & Šimek, Z. (2019) · Environmental Science and Pollution Research · doi:10.1007/s11356-019-05398-2 · Cited by 6

Effects of a probiotic containing Bacillus subtilis on the gut microflora, yolk quality and blood lipid concentrations of laying Pharaon quails

Ermakova, L. P., Ноздрин, Г. А., Тишков, С. Н., Novik, Y. V., Gotovchikov, N. A., & Mensh, I. K. (2020) · Veterinarska stanica · doi:10.46419/vs.52.3.1 · Cited by 6

Sex-specific effects of gut microbiome on shaping bile acid metabolismPreprint

Yang, Y., Chi, L., Hsiao, Y.-C., & Lü, K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.27.601003 · Cited by 6

Bacteria enable tolerance to bile salt exposure in an immune-competent human intestinal model

Li, Y., Wang, C.-M., Zhao, P. Y., Fernez, M. T., & Carrier, R. L. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2514144 · Cited by 5

The swine IsoLoop model of the gut host-microbiota interface enables intra-animal treatment comparisons to advance 3R principles

Bayne, J. E., Charavaryamath, C., Hu, Y., Yousefi, F., Murphy, M., Law, A., Michael, A., Muyyarikkandy, M. S., Nibbering, B., Smits, W. K., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2568706 · Cited by 5

Isolation, Characterization, and Diversity of Probiotic Microorganisms from Different Postpartum Milk of Various Animals

Kathade, S. A., Aswani, M. A., & Anand, P. K. (2022) · International Journal of Health Sciences and Research · doi:10.52403/ijhsr.20220332 · Cited by 5

Novel nitroxide-bile acid conjugates inform substrate requirements for human bile acid transporters

Metry, M., Dirda, N. D. A., Raufman, J., Polli, J. E., & Kao, J. P. Y. (2022) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2022.106335 · Cited by 5

Electrochemical Oxidation of Primary Bile Acids: A Tool for Simulating Their Oxidative Metabolism?

Suarez, L. N., Brückner, L., & Rohn, S. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092491 · Cited by 5

Absence of Intestinal Microbiota during Gestation and Lactation Does Not Alter the Metabolic Response to a Western‐type Diet in Adulthood

Lohuis, M. A. M., Werkman, C. C. N., Harmsen, H. J. M., Tietge, U. J. F., & Verkade, H. J. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800809 · Cited by 5

Gut Microbes: Nuts about Fatty Acids

Holscher, H. D. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa045 · Cited by 5

A dialysis membrane process for the in vitro simulation of bile acids absorption in the small intestine

Akritidou, T., Gaspari, S., Akkermans, S., Joseph, J. A., Smet, C., & van Impe, J. F. M. (2024) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2024.103620 · Cited by 5

Increase in bile acids after sleeve gastrectomy improves metabolism by activating GPBAR1 to increase cAMP in mice with nonalcoholic fatty liver disease

Li, G., Xu, X., Chai, L., Guo, Q., & Wu, W. (2024) · Immunity Inflammation and Disease · doi:10.1002/iid3.1149 · Cited by 4

Ileal FXR Knockdown Ameliorates MASLD Progression in Rats via Modulating Bile Acid Metabolism Mediated by Gut Microbiota

Wang, J., Gao, J., Zhang, Q., Lu, J., Yang, Y., Cai, X., Dong, H., & Lu, L. (2025) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.17017 · Cited by 4

Carrier cross-reactivities of the bile acid reabsorption inhibitors elobixibat, linerixibat, maralixibat, and odevixibat

Billo, V., Neelen, C., Wannowius, M., Neubauer, A., Fühler, B., Hagos, Y., & Geyer, J. (2025) · Journal of Lipid Research · doi:10.1016/j.jlr.2025.100910 · Cited by 4

An Integrated Single-Cell Atlas of the Mouse Ileum Links Nutrient Metabolism with Epithelial and Immune Crosstalk

Tang, Y., Lu, P., Chowanadisai, W., Smith, B. J., Salak‐Johnson, J. L., Lucas, E. A., Clarke, S. L., Conway, T., Tang, M., & Lin, D. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.09.034 · Cited by 4

Role of bile acids in the pathogenesis and metabolic abnormalities of polycystic ovary syndrome (PCOS)

Wang, Y., Shao, X., & Yang, X. (2025) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2025.106919 · Cited by 4

An Update on Bile Acid‐Regulated Signalling in the Pathogenesis of Metabolic Dysfunction‐Associated Steatotic Liver Disease

Shi, J., Wen, Y., Wang, L., Wu, L., Wang, L., Chen, C., Wang, H., & Zhao, C. (2026) · Liver International · doi:10.1111/liv.70586 · Cited by 4

Oxysterols and bile acids - From intertwined biosynthesis to combined quantification

Roumain, M., & Muccioli, G. G. (2026) · Progress in Lipid Research · doi:10.1016/j.plipres.2026.101385 · Cited by 4

Regulation of MAIT cells through host-derived antigens

Ito, E., & Yamasaki, S. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1424987 · Cited by 4

Deoxycholic acid aggravates necrotizing enterocolitis through downregulation of mesenchymal-epithelial transition factor expression

Li, H., Lai, J., Xiao, D., Huang, D., Zhang, Y., Gu, X., Li, F., & Hu, H. (2024) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x2024e14046 · Cited by 4

Clinical Exploration and Physiologically Based Modelling of the Impact of Hepatic Impairment on Entrectinib Pharmacokinetics

Ozbey, A. C., Meneses‐Lorente, G., Simmons, B., McCallum, S., Annaert, P., Parrott, N. J., & Umehara, K. (2025) · Clinical Pharmacokinetics · doi:10.1007/s40262-024-01468-y · Cited by 4

A Single-Cell Atlas of Transcriptome Changes in the Intestinal Epithelium at the Suckling-to-Weaning Transition in Male Rabbits

Malonga, T., Knudsen, C., Alberge, J., Lhuillier, É., Aymard, P., Jones, E., Lencina, C., Despeyroux, M., Riant, É., Cabau, C., et al. (2025) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2025.101628 · Cited by 4

Interaction between W41 of the hepatitis B virus preS1 surface peptide and Y146/F274 of the cellular receptor molecule Na+/taurocholate co-transporting polypeptide is essential for virus entry

Kunz, S. N., Soppa, L., Leidolf, R., Neubauer, A., Lütteke, T., Glebe, D., & Geyer, J. (2025) · Molecular Pharmacology · doi:10.1016/j.molpha.2025.100069 · Cited by 4

A new high-performance thin-layer chromatographic method for determining bile salt hydrolase activity

Rohawi, N. S., Ramasamy, K., Agatonović-Kuštrin, S., & Lim, S. M. (2018) · Journal of Chromatography B · doi:10.1016/j.jchromb.2018.06.009 · Cited by 4

Ontogenesis and Modulation of Intestinal Unesterified Cholesterol Sequestration in a Mouse Model of Niemann–Pick C1 Disease

Lopez, A. M., Ramirez, C. M., Taylor, A. M., Jones, R., Repa, J. J., & Turley, S. D. (2019) · Digestive Diseases and Sciences · doi:10.1007/s10620-019-05736-x · Cited by 4

Intestinal microbiota participates in nonalcoholic fatty liver disease progression by affecting intestinal homeostasis

Zhang, Y., Li, J., Zhang, Y., & Wang, Y. (2021) · World Journal of Clinical Cases · doi:10.12998/wjcc.v9.i23.6654 · Cited by 4

Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph–Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice

Ferlenghi, F., Giorgio, C., Incerti, M., Guidetti, L., Chiodelli, P., Rusnati, M., Tognolini, M., Vacondio, F., Mor, M., & Lodola, A. (2021) · Pharmaceuticals · doi:10.3390/ph15010041 · Cited by 4

Increased fecal glycocholic acid levels correlate with obesity in conjunction with the depletion of archaea: The Dosanco Health Study

Yamamura, R., Okubo, R., Ukawa, S., Nakamura, K., Okada, E., Nakagawa, T., Imae, A., Kimura, T., & Tamakoshi, A. (2025) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2025.109846 · Cited by 3

In vivo tracking of grape marc biomarkers, bioconversion, metabolic tracers, and microbiota modulation in swine fed a polyphenol-rich extract diet

Castillo, A., Celeiro, M., Martínez-Vallespín, B., Rubio, L., Gonzalez-Iglesias, D., Facorro, R., Garcı́a-Jares, C., Zentek, J., & Lores, M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0325079 · Cited by 3

Towards the clinical use of peripheral bile acids: Recommendations to limit their preanalytical and analytical sources of variability

Joseph, S., de Buyl, S., Leclercq, I. A., Serafimov, K., Féron, O., & Clerbaux, L. (2025) · Practical Laboratory Medicine · doi:10.1016/j.plabm.2025.e00508 · Cited by 3

A microbiota-derived bile acid modulates biofilm formation by the probiotic strain Escherichia coli Nissle 1917

Perry, E. K., Udayasuryan, B., Zegeye, E. K., Rose, C. M., Reichelt, M., & Tan, M. (2025) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00854-z · Cited by 3

The resilient microbiome: how baseline gut microbial composition influences response to cancer treatment

Chan, N. S. L., Cross, C., Prestidge, C. A., Wardill, H. R., Bowen, J. M., & Joyce, P. (2026) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2025.2610215 · Cited by 3

Dietary Lauric Acid Suppresses Inflammation, Cholestasis, Hepatocyte Injury, and Senescence in 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-induced Inflammatory Cholangiopathy

Ghosh, S., Devereaux, M. W., Anderson, A. L., Anderson, C. C., D’Alessandro, A., Orlicky, D. J., & Sokol, R. J. (2026) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2026.101731 · Cited by 2

Gut-brain axis: The role of gut microbiota in energy balance and body weight regulation

Tatık, G. P., Baran, Ö., & Dağ, A. (2024) · Clinical Science of Nutrition · doi:10.62210/clinscinutr.2024.98 · Cited by 3

Fluorescent 4-Nitrobenzo-2-oxa-1,3-diazole-Coupled Bile Acids as Probe Substrates of Hepatic and Intestinal Bile Acid Transporters of the Solute Carrier Families SLC10 and SLCO

Drossel, C., Kunz, S., Neelen, C., Georg, M., Hagos, Y., Glebe, D., Göttlich, R., & Geyer, J. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c00589 · Cited by 3

Gut Microbes Take It to the Next Level? First Insights Into Farnesoid X Receptor Agonists of Microbial Origin

Leníček, M., Damink, S. W. M. O., & Schaap, F. G. (2020) · Hepatology · doi:10.1002/hep.31455 · Cited by 3

Quantification of serum fibroblast growth factor-19 concentration in healthy dogs before and after feeding

Myers, J., Granger, L., Keeton, S., Liu, C., & Johnston, A. N. (2021) · American Journal of Veterinary Research · doi:10.2460/ajvr.82.8.676 · Cited by 3

Toxicological Implications of Biological Heterogeneity

Choudhuri, S. (2022) · International Journal of Toxicology · doi:10.1177/10915818211066492 · Cited by 3

Multi-omics analysis reveals gut microbiota-metabolite interactions and their association with liver function in autoimmune overlap syndrome

Wang, Q., Sun, L., Shi, H., Ma, X., Gao, W., Xu, B., Xiao, L., Liu, Y., Huang, C., & Jin, R. (2025) · World Journal of Gastroenterology · doi:10.3748/wjg.v31.i25.106371 · Cited by 3

Bile acid transporter as a bioinspired method for oral therapeutics delivery system

Shahriar, S. M. S., Hasan, M. N., Nurunnabi, M., & Lee, Y.-K. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821352-0.00008-3 · Cited by 3

Role of Bile Acids and Nuclear Receptors in Acupuncture in Improving Crohn’s Disease

Shen, J., Qi, Q., Han, D., Liu, S., Huang, R., Zhu, Y., Zheng, H., Gu, K., Wu, H., & Liu, H. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/5814048 · Cited by 3

MS/MS fragmentation pattern analysis confirms the production of the new esterified bile acids by the human gut microbiotaPreprint

García, C. J., García-Villalba, R., Beltrán, D., Frutos-Lisón, M. D., & Tomás-Barberán, F. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.07.564921 · Cited by 3

Multi-omics Integration of Microbiota Transplant Therapy in Children with Autism Spectrum DisordersPreprint

Mallick, H., Nirmalkar, K., Adams, J. B., & Krajmalnik‐Brown, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.10.681677 · Cited by 3

Gut Microbiota Dysbiosis in the Pathogenesis of Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD)

Mir, G. J., & Ashraf, N. U. (2024) · The International Journal of Gastroenterology and Hepatology Diseases · doi:10.2174/0126662906299478240614100954 · Cited by 2

n-3 Polyunsaturated fatty acids improve sarcopenia by mitochondrial quality control

Bian, D., Su, S., Cheng, X., Shi, Y., Wang, X., & Yan, Y. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.107221 · Cited by 2

Associations between helminth infection status and the composition and concentration of fecal bile acids in school-age children in Uganda

Norton, N. J., Hand, C. M. M., Rowel, C., Adriko, M., Cai, P., McManus, D. P., Egwang, T. G., & Reynolds, L. A. (2025) · Scientific Reports · doi:10.1038/s41598-025-11170-z · Cited by 2

Dietary Gallic Acid Alleviates Hypercholesterolemia in High‐Fat‐Diet‐Fed Mice by Modulating Cholesterol and Bile Acid Metabolism

Wang, Y., Sun, J., Xue, L., Sun, Y., Zhang, K., Fan, M., Qian, H., Li, Y., & Wang, L. (2025) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70291 · Cited by 2

MicroRNA-30c analog C2 decreases plasma cholesterol and atherosclerosis without causing liver injury in preclinical studies

Prakash, B., Chang, Z., Rajan, S., Scarberry, S. R., Gangula, B., Hossain, M. M., Prakashmurthy, C., Valmiki, S., Pulatov, O., Yadav, P. K., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-72276-0 · Cited by 2

The Multifaceted Roles of Gut Microbiota and Their Metabolites in Metabolic Dysfunction-associated Steatotic Liver Disease: A Literature Review

Zhang, Y., Wang, D., Zhuang, B., Zhu, F., Tan, C., Zhang, J., & Zhang, Q. (2026) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2025.00605 · Cited by 2

Exploration of Colonic Mucus as A Dissolution Compartment for Orally Administered Drugs

Wu, M., Karlsson, Ε., & Bergström, C. A. S. (2026) · The AAPS Journal · doi:10.1208/s12248-026-01257-4 · Cited by 2

Gut microbiota-epigenetic interactions in systemic aging: mechanistic drivers for endocrine and reproductive network remodeling and therapeutic modulation

Birigwa, C., Tong, Q., Qu, B., Zuo, T., Yuan, W., Xiong, J., & Luo, J. (2026) · Frontiers in Aging · doi:10.3389/fragi.2026.1826382 · Cited by 2

The impact of gut microbiome on intrahepatic cholestasis of pregnancy—systematic literature review

Donzé, F. J., Eli, N., Simone, N. D., Cavegn, B. B., & Mueller, M. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1859397 · Cited by 2

Host–microbial co-metabolites: from biogenesis to immunomodulation and implications for health and disease

Wang, Y., Zhao, L., Zou, Y., & Nie, L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1775938 · Cited by 2

BILE ACID TRANSPORTERS

Ayewoh, E. N., & Swaan, P. W. (2022) · Wiley eBooks · doi:10.1002/9781119739883.ch9 · Cited by 2

Gut Microbiome Metabolites and the Intestinal Homeostasis

Metwally, H., & Kishimoto, T. (2024) · Journal of Clinical Research and Reports · doi:10.31579/2690-1919/371 · Cited by 2

The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat

Cussotto, S., Golubeva, A. V., Gallardo, A. L., Bastiaanssen, T. F. S., Zhdanov, A. V., Moloney, G. M., Scaife, C., English, J. A., Joyce, S. A., Dinan, T. G., et al. (2025) · Experimental Physiology · doi:10.1113/ep092451 · Cited by 2

DISEASES OF THE LIVER AND INTESTINAL MICROBIOME

Васильевна, В. Г., Хавкин, А. И., Андреевна, С. Т., Nikitin, A. V., & Matkash, V. V. (2019) · Russian Pediatric Journal · doi:10.18821/1560-9561-2018-21-6-366-377 · Cited by 2

Intestinally Active Therapies for Hypercholesterolemia: Ezetimibe, Bile Acid Resins, and Plant Sterols

Dayspring, T. D., & Pokrywka, G. S. (2020) · Contemporary cardiology · doi:10.1007/978-3-030-56514-5_13 · Cited by 2

Bile Acids as Regulatory Signalling Molecules

Matz‐Soja, M. (2020) · Springer eBooks · doi:10.1007/978-3-030-39684-8_5 · Cited by 2

Effect of Qiwei Baizhu Powder on the Intestinal Flora of the Splenoasthenic Diarrhea Mice

SHI, X., Li, N., Li, J., Yang, Q., KAN, M., & Qu, X. (2020) · Indian Journal of Pharmaceutical Sciences · doi:10.36468/pharmaceutical-sciences.710 · Cited by 2

Gut Microbiota in Obesity and Bariatric Surgery: Where Do We Stand?

Georgiou, K. E. (2021) · The microbiomes of humans, animals, plants, and the environment · doi:10.1007/978-3-030-59642-2_6 · Cited by 2

Metabolic integration of the «gut – liver»: theoretical basis of interaction and therapeutic prospects

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Wang, G., Guan, J., Yang, Q., Wu, F., Shao, J., Zhou, Q., Guo, Z., Ren, Y., Zhu, H., & Chen, Z. (2022) · Research Square · doi:10.21203/rs.3.rs-215296/v2 · Cited by 2

Metabolic links among milk, genes and gut

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Multi-omics analysis highlights the link of aging-related cognitive decline with systemic inflammation and alterations of tissue-maintenancePreprint

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Bile acid metabolism

Truong, J. K., & Dawson, P. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-824048-9.00016-x · Cited by 1

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Pharmacological Role of Deoxycholic Acid in the Regulation of Aging in Drosophila melanogaster

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Whole pulse ingredient inclusion in macronutrient-balanced diets increased fecal concentrations of propionic acid but not total bile acids in healthy adult large-breed dogs after 20 weeks

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Paeoniflorin: A Review of its Hepatointestinal Protective Effects and Molecular Mechanisms

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Metabolites as potential tools for the diagnosis and treatment of saccular intracranial aneurysms

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The impact of solid and liquid lipids and their lipolysis on griseofulvin bioavailability. In vitro dissolution, in vivo and ex vivo porcine model study

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The Analysis of Transcriptomes and Microorganisms Reveals Differences Between the Intestinal Segments of New Zealand Rabbits

Tang, D., Chen, S., Tang, C., Li, X., Li, M., Li, X., Zhang, K., & Ma, J. (2026) · Animals · doi:10.3390/ani16030390 · Cited by 1

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

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Localized Rectal Dextran Sulfate Sodium-Induced Colitis Is Associated with Small-Intestinal Shortening and Gut–Liver Axis-Related Alterations

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Perfluoroalkyl and polyfluoroalkyl substances exposure and liver disease: A review

Peng, J., Gong, R., Li, R., Li, L., Yu, H., & Wen, Q. (2026) · Toxicology · doi:10.1016/j.tox.2026.154509 · Cited by 1

Gut microbial metabolites in colorectal cancer: dual roles in tumorigenesis, immune crosstalk, and therapeutic innovation

Jin, Y. G., Zhu, H., Fan, J., & Xu, H. G. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1693161 · Cited by 1

Lithocholic acid induces T3SS-dependent formation of invasion-competent Shigella flexneri aggregates

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Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids

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Advances in research on the effects of bile acids and their receptors on intestinal function

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Meetings and Courses

Lei, S.-Y. (2015) · Hepatobiliary & pancreatic diseases international · doi:10.1016/s1499-3872(15)60407-6

Bile acid metabolism and signaling, the microbiota, and metabolic disease

Cai, J., Rimal, B., Jiang, C., Chiang, J. Y. L., & Patterson, A. D. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108238 · Cited by 529

A Recent Ten-Year Perspective: Bile Acid Metabolism and Signaling

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