Intestinal transport and metabolism of bile acids

Diet rapidly and reproducibly alters the human gut microbiome

David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V., Devlin, A. S., Varma, Y., Fischbach, M. A., et al. (2014) · Nature · doi:10.1038/nature12820 · Cited by 10,100

Host-gut microbiota metabolic interactions

Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S. (2012) · Science · doi:10.1126/science.1223813 · Cited by 4,760

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, J., Duncan, A. E., Kau, A. L., Griffin, N. W., Lombard, V., Henrissat, B., Bain, J. R., et al. (2013) · Science · doi:10.1126/science.1241214 · Cited by 3,788

Bile salt biotransformations by human intestinal bacteria

Ridlon, J. M., Kang, D.-J., & Hylemon, P. B. (2006) · Journal of Lipid Research · doi:10.1194/jlr.r500013-jlr200 · Cited by 2,829

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

Sayin, S. I., Wahlström, A., Felin, J., Jäntti, S., Marschall, H.-U., Bamberg, K., Angelin, B., Hyötyläinen, T., Orešič, M., & Bäckhed, F. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.01.003 · Cited by 2,331

The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

Russell, D. W. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161712 · Cited by 2,069

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice

Devkota, S., Wang, Y., Musch, M. W., Leone, V., Fehlner-Peach, H., Nadimpalli, A., Antonopoulos, D. A., Jabri, B., & Chang, E. B. (2012) · Nature · doi:10.1038/nature11225 · Cited by 1,904

The interaction between bacteria and bile

Begley, M., Gahan, C. G. M., & Hill, C. (2004) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2004.09.003 · Cited by 1,776

The microbiome and cancer

Schwabe, R. F., & Jobin, C. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3610 · Cited by 1,689

Bile Acid Metabolism and Signaling

Chiang, J. Y. L. (2013) · Comprehensive physiology · doi:10.1002/cphy.c120023 · Cited by 1,662

Reduction in circulating bile acid and restricted diffusion across the intestinal epithelium are associated with a decrease in blood cholesterol in the presence of oat β‐glucan

Gunness, P., Michiels, J., Vanhaecke, L., SMET, S. D., Kravchuk, O. Y., van de Meene, A., & Gidley, M. J. (2016) · The FASEB Journal · doi:10.1096/fj.201600465r · Cited by 75

Bile Acids Transporters of Enterohepatic Circulation for Targeted Drug Delivery

Durník, R., Sindlerova, L. S., Babica, P., & Jurček, O. (2022) · Molecules · doi:10.3390/molecules27092961 · Cited by 73

A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2

Albrich, W. C., Ghosh, T. S., Ahearn-Ford, S., Mikaeloff, F., Lunjani, N., Forde, B. M., Suh, N., Kleger, G., Pietsch, U., Frischknecht, M., et al. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2073131 · Cited by 72

Unraveling the gut microbiota’s role in obesity: key metabolites, microbial species, and therapeutic insights

Iqbal, M., Qian, Y., Tang, J., & Xiang, J. (2025) · Journal of Bacteriology · doi:10.1128/jb.00479-24 · Cited by 72

Circulating bile acids predict outcome in critically ill patients

Horvatits, T., Drolz, A., Rutter, K., Roedl, K., Langouche, L., den Berghe, G. V., Fauler, G., Meyer, B., Hülsmann, M., Heinz, G., et al. (2017) · Annals of Intensive Care · doi:10.1186/s13613-017-0272-7 · Cited by 72

Gut Microbiota‐Bile Acid Crosstalk in Diarrhea‐Irritable Bowel Syndrome

Zhan, K., Zheng, H., Jian-qing, L., Wu, H., Qin, S., Luo, L., & Huang, S. (2020) · BioMed Research International · doi:10.1155/2020/3828249 · Cited by 72

Gut microbiome and cardiovascular disease

Zhao, Y., & Wang, Z. (2020) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000720 · Cited by 70

Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions

Hsiao, A., & Zhu, J. (2020) · Virulence · doi:10.1080/21505594.2020.1845039 · Cited by 69

Bile Acid and Gut Microbiota in Irritable Bowel Syndrome

Min, Y. W., Rezaie, A. R., & Pimentel, M. (2022) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm22129 · Cited by 69

Ileitis promotes MASLD progression via bile acid modulation and enhanced TGR5 signaling in ileal CD8+ T cells

Zheng, C., Wang, L., Zou, T., Lian, S., Luo, J., Lu, Y., Hao, H., Xu, Y., Xiang, Y., Zhang, X., et al. (2024) · Journal of Hepatology · doi:10.1016/j.jhep.2023.12.024 · Cited by 70

Gut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty Liver Disease

Aragonès, G., González-García, S., Aguilar, C., Richart, C., & Auguet, T. (2019) · BioMed Research International · doi:10.1155/2019/8507583 · Cited by 69

Connecting the Dots Between Inflammatory Bowel Disease and Metabolic Syndrome: A Focus on Gut-Derived Metabolites

Verdugo‐Meza, A., Ye, J., Dadlani, H., Ghosh, S., & Gibson, D. L. (2020) · Nutrients · doi:10.3390/nu12051434 · Cited by 69

Metabolism and Pharmacokinetics of Phytochemicals in the Human Body

Rathaur, P., & Johar, K. (2020) · Current Drug Metabolism · doi:10.2174/1389200221666200103090757 · Cited by 68

Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples

Gómez, C., Stücheli, S., Kratschmar, D. V., Bouitbir, J., & Odermatt, A. (2020) · Metabolites · doi:10.3390/metabo10070282 · Cited by 68

IBD and Bile Acid Absorption: Focus on Pre-clinical and Clinical Observations

Fitzpatrick, L. R., & Jenabzadeh, P. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00564 · Cited by 66

Distinct Plasma Bile Acid Profiles of Biliary Atresia and Neonatal Hepatitis Syndrome

Zhou, K., Wang, J., Xie, G., Zhou, Y., Yan, W., Pan, W., Che, Y., Zhang, T., Wong, L. L., Kwee, S. A., et al. (2015) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5b00676 · Cited by 66

Obesity and cancer: A mechanistic overview of metabolic changes in obesity that impact genetic instability

Kompella, P., & Vásquez, K. M. (2019) · Molecular Carcinogenesis · doi:10.1002/mc.23048 · Cited by 66

The Effect of Lithocholic Acid on the Gut-Liver Axis

Sheng, W., Ji, G., & Zhang, L. R. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.910493 · Cited by 65

Multiple sclerosis patients have a diminished serologic response to vitamin D supplementation compared to healthy controls

Bhargava, P., Steele, S. U., Waubant, E. L., Revirajan, N., Marcus, J. F., Dembele, M., Cassard, S. D., Hollis, B. W., Crainiceanu, C. M., & Mowry, E. M. (2015) · Multiple Sclerosis Journal · doi:10.1177/1352458515600248 · Cited by 65

Increased circulating conjugated primary bile acids are associated with hyperandrogenism in women with polycystic ovary syndrome

Zhang, B., Shen, S., Gu, T., Hong, T., Liu, J., Sun, J., Wang, H., Bi, Y., & Zhu, D. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.03.005 · Cited by 64

Mode and Mechanism of Action of Omega-3 and Omega-6 Unsaturated Fatty Acids in Chronic Diseases

Xu, R., Molenaar, A. J., Chen, Z., & Yuan, Y. (2025) · Nutrients · doi:10.3390/nu17091540 · Cited by 64

Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids

Lan, K., Su, M., Xie, G., Ferslew, B. C., Brouwer, K. L. R., Rajani, C., Liu, C., & Jia, W. P. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b00573 · Cited by 64

Organic solute transporter‐β (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis

Sultan, M. I., Rao, A., Elpeleg, O. N., Vaz, F. M., Abu‐Libdeh, B., Karpen, S. J., & Dawson, P. A. (2017) · Hepatology · doi:10.1002/hep.29516 · Cited by 64

Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet–fed mice

Takahashi, S., Luo, Y., Ranjit, S., Xie, C., Libby, A. E., Orlicky, D. J., Dvornikov, A. S., Wang, X. X., Myakala, K., Jones, B. A., et al. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.011913 · Cited by 64

Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome

Altaha, B., Heddes, M., Pilorz, V., Niu, Y., Gorbunova, E., Gigl, M., Kleigrewe, K., Oster, H., Haller, D., & Kießling, S. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101628 · Cited by 63

Update on gut microbiota in cardiovascular diseases

Qian, B., Zhang, K., Li, Y., & Sun, K. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.1059349 · Cited by 63

Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transport

Xie, C., Takahashi, S., Brocker, C. N., He, S., Chen, L., Xie, G., Jang, K., Gao, X., Krausz, K. W., Qu, A., et al. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2019.05.014 · Cited by 63

Gut-Brain Axis a Key Player to Control Gut Dysbiosis in Neurological Diseases

Pan, I., Issac, P. K., Rahman, M. M., Guru, A., & Arockiaraj, J. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03691-3 · Cited by 62

Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin

Lee, J. S., Han, P., Chaudhury, R., Khan, S. N., Bickerton, S., McHugh, M. D., Park, H. B., Siefert, A. L., Rea, G., Carballido, J. M., et al. (2021) · Nature Biomedical Engineering · doi:10.1038/s41551-021-00791-0 · Cited by 61

Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption

Kim, Y., Byun, S., Seok, S., Guo, G. L., Xu, H. E., KEMPER, B. W., & Kemper, J. K. (2018) · Gastroenterology · doi:10.1053/j.gastro.2018.11.061 · Cited by 61

Gut Microbiota Signatures in Colorectal Cancer as a Potential Diagnostic Biomarker in the Future: A Systematic Review

Herlo, L.-F., Sălcudean, A., Șirli, R., Iurciuc, S., Herlo, A., Twakor, A. N., Alexandrescu, L., & Dumache, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147937 · Cited by 60

Gut Microbiome Regulation of Gut Hormone Secretion

Chao, J. L., Coleman, R. A., Keating, D. J., & Martin, A. M. (2025) · Endocrinology · doi:10.1210/endocr/bqaf004 · Cited by 60

Relevance in the Use of Appropriate Internal Standards for Accurate Quantification Using LC–MS/MS: Tauro-Conjugated Bile Acids as an Example

Krautbauer, S., Büchler, C., & Liebisch, G. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b02596 · Cited by 59

Bile acid transporter-mediated oral absorption of insulin via hydrophobic ion-pairing approach

Bashyal, S., Seo, J., Choi, Y. W., & Lee, S. K. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.08.060 · Cited by 58

Present and Future: Crosstalks Between Polycystic Ovary Syndrome and Gut Metabolites Relating to Gut Microbiota

Zhang, M., Hu, R., Huang, Y., Zhou, F., Li, F., Liu, Z., Geng, Y., Dong, H., Ma, W., Song, K., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.933110 · Cited by 58

Bile salts in control of lipid metabolism

Schonewille, M., de Boer, J. F., & Groen, A. K. (2016) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000303 · Cited by 58

Tauroursodeoxycholic acid protects bile acid homeostasis under inflammatory conditions and dampens Crohn's disease-like ileitis

den Bossche, L. V., Borsboom, D., Devriese, S., Welden, S. V., Holvoet, T., Devisscher, L., Hindryckx, P., Vos, M. D., & Laukens, D. (2017) · Laboratory Investigation · doi:10.1038/labinvest.2017.6 · Cited by 58

The Interface of Vibrio cholerae and the Gut Microbiome

Cho, J. Y., Liu, R., Macbeth, J. C., & Hsiao, A. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1937015 · Cited by 58

Factors affecting separation and detection of bile acids by liquid chromatography coupled with mass spectrometry in negative mode

Yin, S., Su, M., Xie, G., Li, X., Wei, R., Liu, C., Lan, K., & Jia, W. P. (2017) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-017-0489-1 · Cited by 56

Bile Acids and GPBAR-1: Dynamic Interaction Involving Genes, Environment and Gut Microbiome

Portincasa, P., Ciaula, A. D., Garruti, G., Vacca, M., Angelis, M. D., & Wang, D. Q. ‐. (2020) · Nutrients · doi:10.3390/nu12123709 · Cited by 56

Unraveling Host-Gut Microbiota Dialogue and Its Impact on Cholesterol Levels

Villette, R., Pukar, K. C., Béliard, S., Salas-Tapia, M. F., Rainteau, D. P., Guérin, M., & Lesnik, P. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00278 · Cited by 55

Physiology of Electrolyte Transport in the Gut: Implications for Disease

Rao, M. C. (2019) · Comprehensive physiology · doi:10.1002/cphy.c180011 · Cited by 54

Effects of dietary pectin on the profile and transport of intestinal bile acids in young pigs

Fang, W., Zhang, L., Meng, Q., Wu, W., Lee, Y. K., Xie, J., & Zhang, H. (2018) · Journal of Animal Science · doi:10.1093/jas/sky327 · Cited by 53

Overview of Progressive Familial Intrahepatic Cholestasis

Hassan, S., & Hertel, P. M. (2022) · Clinics in Liver Disease · doi:10.1016/j.cld.2022.03.003 · Cited by 53

Probiotics for the treatment of hyperlipidemia: Focus on gut-liver axis and lipid metabolism

You, M. S., Zhou, L., Wu, F., Zhang, L., Zhu, S.-X., & Zhang, H. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107694 · Cited by 53

Molecular physiology of chemical defenses in a poison frog

Caty, S. N., Alvarez‐Buylla, A., Byrd, G. D., Vidoudez, C., Roland, A. B., Tapia, E., Budnik, B., Trauger, S. A., Coloma, L. A., & O’Connell, L. A. (2019) · Journal of Experimental Biology · doi:10.1242/jeb.204149 · Cited by 53

Dietary wood pulp-derived sterols modulation of cholesterol metabolism and gut microbiota in high-fat-diet-fed hamsters

Li, X., Wang, H., Wang, T., Zheng, F., Wang, H., & Wang, C. (2019) · Food & Function · doi:10.1039/c8fo02271b · Cited by 52

The role of bile acids in regulating glucose and lipid metabolism

Yu, H., Nie, R., & Shen, C. (2023) · Endocrine Journal · doi:10.1507/endocrj.ej22-0544 · Cited by 52

Ethanol-induced changes to the gut microbiome compromise the intestinal homeostasis: a review

Sosnowski, K., & Przybyłkowski, A. M. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2393272 · Cited by 52

Gut microbiota-associated bile acid deconjugation accelerates hepatic steatosis in ob/ob mice

Park, M.-Y., Kim, S. J., Ko, E., Ahn, S., Seo, H., & Sung, M. (2016) · Journal of Applied Microbiology · doi:10.1111/jam.13158 · Cited by 52

Faecal bile acids are natural ligands of the mouse accessory olfactory system

Doyle, W. I., Dinser, J. A., Cansler, H. L., Zhang, X., Dinh, D. D., Browder, N. S., Riddington, I. M., & Meeks, J. P. (2016) · Nature Communications · doi:10.1038/ncomms11936 · Cited by 52

The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology

Ridlon, J. M., Daniel, S. L., & Gaskins, H. R. (2023) · Journal of Lipid Research · doi:10.1016/j.jlr.2023.100392 · Cited by 51

The regulation of tissue-specific farnesoid X receptor on genes and diseases involved in bile acid homeostasis

Xiang, D., Yang, J., Liu, L., Yu, H., Gong, X., & Liu, D. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115606 · Cited by 51

Gut-liver axis: Pathophysiological concepts and medical perspective in chronic liver diseases

Rodrigues, S. G., der Merwe, V., Krag, A. A., & Wiest, R. (2024) · Seminars in Immunology · doi:10.1016/j.smim.2023.101859 · Cited by 51

The physiology of MASLD: molecular pathways between liver and adipose tissues

Lee, W., Kipp, Z. A., Bates, E. A., Pauss, S. N., Martinez, G. J., & Hinds, T. D. (2025) · Clinical Science · doi:10.1042/cs20257571 · Cited by 52

FGF21 acts as a negative regulator of bile acid synthesis

Chen, M. M., Hale, C., Stanislaus, S., Xu, J., & Véniant, M. M. (2018) · Journal of Endocrinology · doi:10.1530/joe-17-0727 · Cited by 51

Bile acids as regulatory molecules and potential targets in metabolic diseases

Xie, A.-J., Mai, C.-T., Zhu, Y. Z., Liu, X., & Xie, Y. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120152 · Cited by 51

Amino Acids in Microbial Metabolism and Function

Dai, Z., Wu, Z., Zhu, W., & Wu, G. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-85686-1_7 · Cited by 50

Gut Microbiota at the Crossroad of Hepatic Oxidative Stress and MASLD

Termite, F., Archilei, S., D’Ambrosio, F., Petrucci, L., Viceconti, N., Iaccarino, R., Liguori, A., Gasbarrini, A., & Miele, L. (2025) · Antioxidants · doi:10.3390/antiox14010056 · Cited by 50

Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid–Induced Injury

Ferrebee, C. B., Li, J., Haywood, J., Pachura, K. J., Robinson, B. S., Hinrichs, B. H., Jones, R. M., Rao, A., & Dawson, P. A. (2018) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2018.01.006 · Cited by 50

Diet, Immunity, and Microbiota Interactions: An Integrative Analysis of the Intestine Transcriptional Response and Microbiota Modulation in Gilthead Seabream (Sparus aurata) Fed an Essential Oils-Based Functional Diet

Firmino, J. P., Vallejos‐Vidal, E., Balebona, M. C., Ramayo‐Caldas, Y., Cerezo, I. M., Salomón, R., Tort, L., Estévez, A., Moríñigo, M. Á., Reyes‐López, F. E., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.625297 · Cited by 50

Adaptation of the gut pathobiont Enterococcus faecalis to deoxycholate and taurocholate bile acids

Repoila, F., Wessner, F., Guérin, C., Lacoux, C., Tiwari, S., Jaiswal, A. K., Santana, M. P., Kennedy, S., Quinquis, B., Rainteau, D. P., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-12552-3 · Cited by 49

Review of the Relationships Between Human Gut Microbiome, Diet, and Obesity

Patloka, O., Komprda, T., & Franke, G. (2024) · Nutrients · doi:10.3390/nu16233996 · Cited by 50

Bile Acids in Cholestasis and its Treatment

Arab, J. P., Cabrera, D., & Arrese, M. A. (2017) · Annals of Hepatology · doi:10.5604/01.3001.0010.5497 · Cited by 49

Bile Metabolism and Lithogenesis

Dosch, A. R., Imagawa, D. K., & Jutric, Z. (2019) · Surgical Clinics of North America · doi:10.1016/j.suc.2018.12.003 · Cited by 49

Gut microbiota and their metabolites in the progression of non-alcoholic fatty liver disease

Zhou, J., Tripathi, M., Sinha, R. A., Singh, B. K., & Yen, P. M. (2021) · Hepatoma Research · doi:10.20517/2394-5079.2020.134 · Cited by 49

Bile acid patterns in commercially available oxgall powders used for the evaluation of the bile tolerance ability of potential probiotics

Hu, P.-L., Yuan, Y.-H., Yue, T.-L., & Guo, C.-F. (2018) · PLOS ONE · doi:10.1371/journal.pone.0192964 · Cited by 48

The role and mechanisms of gut microbiota in diabetic nephropathy, diabetic retinopathy and cardiovascular diseases

Lv, Q., Li, Z., Sui, A., Yang, X., Han, Y., & Yao, R. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.977187 · Cited by 48

Bile Acids in Hepatic Encephalopathy

DeMorrow, S. (2018) · Journal of Clinical and Experimental Hepatology · doi:10.1016/j.jceh.2018.04.011 · Cited by 48

Metabolic Effects of Bile Acids: Potential Role in Bariatric Surgery

Flynn, C. R., Albaugh, V. L., & Abumrad, N. N. (2019) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2019.04.014 · Cited by 48

A sensitive and efficient method for simultaneous profiling of bile acids and fatty acids by UPLC-MS/MS

Hu, T., An, Z., Shi, C., Li, P., & Liu, L. (2019) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2019.112815 · Cited by 48

A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings

Voronova, V., Sokolov, V. V., Al-Khaifi, A., Straniero, S., Kumar, C., Peskov, K. V., Helmlinger, G., Rudling, M. J., & Angelin, B. (2020) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2020.02.005 · Cited by 47

Host–microbiome orchestration of the sulfated metabolome

D’Agostino, G. D., Chaudhari, S. N., & Devlin, A. S. (2024) · Nature Chemical Biology · doi:10.1038/s41589-023-01526-9 · Cited by 45

Polyunsaturated Fatty Acids (PUFAs): Sources, Digestion, Absorption, Application and Their Potential Adjunctive Effects on Visual Fatigue

Duan, H., Song, W. D., Zhao, J., & Yan, W. (2023) · Nutrients · doi:10.3390/nu15112633 · Cited by 44

Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage

Neuman, M. G., French, S. W., Zakhari, S., Malnick, S. D. H., Seitz, H. K., Cohen, L. B., Salaspuro, M. P., Voinea‐Griffin, A., Barasch, A., Kirpich, I., et al. (2017) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2017.01.003 · Cited by 44

Roles of Ileal ASBT and OSTα-OSTβ in Regulating Bile Acid Signaling

Dawson, P. A. (2017) · Digestive Diseases · doi:10.1159/000450987 · Cited by 44

Rumen microbiome-driven insight into bile acid metabolism and host metabolic regulation

Zhang, B., Jiang, X., Yu, Y., Cui, Y., Wang, W., Luo, H., Stergiadis, S., & Wang, B. (2024) · The ISME Journal · doi:10.1093/ismejo/wrae098 · Cited by 43

Altered serum bile acid profile in fibromyalgia is associated with specific gut microbiome changes and symptom severity

Minerbi, A., González, E., Brereton, N. J. B., Fitzcharles, M., Chevalier, S., & Shir, Y. (2022) · Pain · doi:10.1097/j.pain.0000000000002694 · Cited by 43

Asynchronous rhythms of circulating conjugated and unconjugated bile acids in the modulation of human metabolism

Al-Khaifi, A., Straniero, S., Voronova, V., Chernikova, D., Sokolov, V. V., Kumar, C., Angelin, B., & Rudling, M. (2018) · Journal of Internal Medicine · doi:10.1111/joim.12811 · Cited by 42

The Role of FGF19 and MALRD1 in Enterohepatic Bile Acid Signaling

Wang, L. X., Frey, M. R., & Kohli, R. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.799648 · Cited by 42

Role of gut-liver axis and glucagon-like peptide-1 receptor agonists in the treatment of metabolic dysfunction-associated fatty liver disease

Rochoń, J., Kalinowski, P., Szymanek-Majchrzak, K., & Grąt, M. (2024) · World Journal of Gastroenterology · doi:10.3748/wjg.v30.i23.2964 · Cited by 41

Bile acids impact the microbiota, host, and C. difficile dynamics providing insight into mechanisms of efficacy of FMTs and microbiota-focused therapeutics

McMillan, A. S., & Theriot, C. M. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2393766 · Cited by 41

Western diet‐induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis

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Probiotics, prebiotics, and synbiotics in nonalcoholic fatty liver disease and alcohol-associated liver disease

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Unraveling MASLD: The Role of Gut Microbiota, Dietary Modulation, and AI-Driven Lifestyle Interventions

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Supramolecular structures in lipid digestion and implications for functional food delivery

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Intestinal Flora Derived Metabolites Affect the Occurrence and Development of Cardiovascular Disease

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Pediatric Cholestatic Diseases: Common and Unique Pathogenic Mechanisms

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Interplay of Oxidative Stress, Gut Microbiota, and Nicotine in Metabolic-Associated Steatotic Liver Disease (MASLD)

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Middle-distance running acutely influences the concentration and composition of serum bile acids: Potential implications for cancer risk?

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Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency

Mao, F., Liu, T., Hou, X., Zhao, H., He, W., Li, C., Jing, Z., Sui, J., Wang, F., Liu, X., et al. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.007179 · Cited by 39

Modulating tumor immunity by metronomic dosing of oxaliplatin incorporated in multiple oral nanoemulsion

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Reciprocal interactions between gut microbiota and autophagy

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Ulcerative colitis: functional analysis of the in-depth proteome

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Oral Delivery of Biologics via the Intestine

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The intestinal microbiota as a therapeutic target in the treatment of NAFLD and ALD

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Lysimachia christinae polysaccharide attenuates diet-induced hyperlipidemia via modulating gut microbes-mediated FXR–FGF15 signaling pathway

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Alterations in bile acid kinetics after bariatric surgery in patients with obesity with or without type 2 diabetes

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Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids

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Advances in research on the effects of bile acids and their receptors on intestinal function

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Meetings and Courses

Lei, S.-Y. (2015) · Hepatobiliary & pancreatic diseases international · doi:10.1016/s1499-3872(15)60407-6

Bile acid metabolism and signaling, the microbiota, and metabolic disease

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A Recent Ten-Year Perspective: Bile Acid Metabolism and Signaling

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