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Thematic Review Series: Lipid Transfer Proteins Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

Shen, Wen-Jun, Asthana, Shailendra, Kraemer, Fredric B., Azhar, Salman·2018·Journal of Lipid Research
DOI 10.1194/jlr.r083121
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  • SCARB1 encodes a scavenger receptor that binds a variety of ligands including LDL, has SREBP-binding sites in its promoter region, and is expressed in hepatocytes.

    “SCARB1 encodes a scavenger receptor that binds a variety of ligands including LDL, has SREBP-binding sites in its promoter region, and is expressed in hepatocytes[32].”

    From Genome-scale CRISPR screening for modifiers of cellular LDL uptake (2021) · cites this paper as [32]

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Research works printed but not linked: 239

  1. Russell, 2009, Fifty years of advances in bile acid synthesis and metabolism, J. Lipid Res., 50, S120, 10.1194/jlr.R800026-JLR200 · DOI · Paper page
  2. Miller, 2011, Early steps in steroidogenesis: intracellular cholesterol trafficking, J. Lipid Res., 52, 2111, 10.1194/jlr.R016675 · DOI
  3. Glass, 1983, Dissociation of tissue uptake of cholesterol ester from that of apoprotein A-I of rat plasma high density lipoprotein: selective delivery of cholesterol ester to liver, adrenal, and gonad, Proc. Natl. Acad. Sci. USA., 80, 5435, 10.1073/pnas.80.17.5435 · DOI
  4. Quarfordt, 1980, The uptake of high density lipoprotein cholesteryl ester in the perfused rat liver, J. Biol. Chem., 255, 2934, 10.1016/S0021-9258(19)85830-1 · DOI
  5. Reaven, 1984, Morphological evidence that high density lipoproteins are not internalized by steroid-producing cells during in situ organ perfusion, J. Clin. Invest., 74, 1384, 10.1172/JCI111549 · DOI
  6. Glass, 1985, Uptake of high-density lipoprotein-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro, J. Biol. Chem., 260, 744, 10.1016/S0021-9258(20)71160-9 · DOI
  7. Reaven, 1986, Uptake of low density lipoproteins by rat tissues. Special emphasis on the luteinized ovary, J. Clin. Invest., 77, 1971, 10.1172/JCI112526 · DOI
  8. Azhar, 1989, Utilization of cholesterol-rich lipoproteins by perfused rat adrenals, J. Lipid Res., 30, 1799, 10.1016/S0022-2275(20)38226-2 · DOI
  9. Stein, 1983, Metabolism of HDL-cholesteryl ester in the rat, studied with a nonhydrolyzable analog, cholesteryl linoleyl ether, Biochim. Biophys. Acta., 752, 98, 10.1016/0005-2760(83)90237-0 · DOI
  10. Gwynne, 1989, Rat adrenal uptake and metabolism of high density lipoprotein cholesteryl ester, J. Biol. Chem., 264, 8141, 10.1016/S0021-9258(18)83161-1 · DOI
  11. Azhar, 1998, Simultaneous induction of an HDL receptor protein (SR-BI) and the selective uptake of HDL-cholesteryl esters in a physiologically relevant steroidogenic cell model, J. Lipid Res., 39, 1616, 10.1016/S0022-2275(20)32191-X · DOI
  12. Azhar, 1998, Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis, J. Clin. Endocrinol. Metab., 83, 983
  13. Reaven, 2000, Expression and microvillar localization of scavenger receptor class B, type I (SR-BI) and selective cholesteryl ester uptake in Leydig cells from rat testis, J. Lipid Res., 41, 343, 10.1016/S0022-2275(20)34473-4 · DOI
  14. Scobey, 1989, Delivery of high-density lipoprotein free and esterified cholesterol to bile by the perfused monkey liver, Am. J. Physiol., 257, G644
  15. Pieters, 1991, Selective uptake of cholesteryl esters from apolipoprotein-E-free high-density lipoproteins by rat parenchymal cells in vivo is efficiently coupled to bile acid synthesis, Biochem. J., 280, 359, 10.1042/bj2800359 · DOI
  16. Fluiter, 1996, Increased selective uptake in vivo and in vitro of oxidized cholesteryl esters from high-density lipoprotein by rat liver parenchymal cells, Biochem. J., 319, 471, 10.1042/bj3190471 · DOI
  17. Guertin, 1997, Oxidative tyrosylation of high density lipoprotein impairs biliary sterol secretion in rats, Atherosclerosis., 131, 35, 10.1016/S0021-9150(97)06085-1 · DOI
  18. Pittman, 1987, Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters, J. Biol. Chem., 262, 2435, 10.1016/S0021-9258(18)61523-6 · DOI
  19. Rinninger, 1998, Selective uptake of cholesteryl esters from high-density lipoprotein-derived LpA-I and LpA-I:A-II particles by hepatic cells in culture, Biochim. Biophys. Acta., 1393, 277, 10.1016/S0005-2760(98)00082-4 · DOI
  20. Despres, 1988, Selective uptake of HDL cholesterol ester by human fat cells, Am. J. Physiol., 254, E667
  21. Schorsch, 1997, Selective uptake of high density lipoprotein-associated cholesterylesters by differentiated Ob1771 adipocytes is modulated by endogenous and exogenous lipoprotein lipase, FEBS Lett., 414, 507, 10.1016/S0014-5793(97)01061-2 · DOI
  22. Stein, 1987, Preferential uptake of cholesteryl ester-HDL by cultured macrophages, Atherosclerosis., 65, 151, 10.1016/0021-9150(87)90016-5 · DOI
  23. Rinninger, 1994, Selective uptake of high-density lipoprotein-associated cholesteryl esters and high-density lipoprotein particle uptake by human monocyte-macrophages, Atherosclerosis., 105, 145, 10.1016/0021-9150(94)90044-2 · DOI
  24. Leitersdorf, 1986, The role of apolipoproteins of HDL in the selective uptake of cholesteryl linoleyl ether by cultured rat and bovine adrenal cells, Biochim. Biophys. Acta., 878, 320, 10.1016/0005-2760(86)90239-0 · DOI
  25. Acton, 1996, Identification of scavenger receptor SR-BI as a high density lipoprotein receptor, Science., 271, 518, 10.1126/science.271.5248.518 · DOI · Paper page
  26. Acton, 1994, Expression cloning of SR-BI, a CD36-related class B scavenger receptor, J. Biol. Chem., 269, 21003, 10.1016/S0021-9258(17)31921-X · DOI
  27. Calvo, 1993, Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family, J. Biol. Chem., 268, 18929, 10.1016/S0021-9258(17)46716-0 · DOI
  28. Mizutani, 1997, Cloning, characterization, and cellular distribution of rat scavenger receptor class B type I (SRBI) in the ovary, Biochem. Biophys. Res. Commun., 234, 499, 10.1006/bbrc.1997.6646 · DOI
  29. Ritsch, 2004, Molecular characterization of rabbit scavenger receptor class B types I and II: portal to central vein gradient of expression in the liver, J. Lipid Res., 45, 214, 10.1194/jlr.M300353-JLR200 · DOI
  30. Kim, 2004, Molecular cloning and endometrial expression of porcine high density lipoprotein receptor SR-BI during the estrous cycle and early pregnancy, Mol. Cell. Endocrinol., 222, 105, 10.1016/j.mce.2004.04.008 · DOI
  31. Rajapaksha, 1997, Sequence of the bovine HDL-receptor (SR-BI) cDNA and changes in receptor mRNA expression during granulosa cell luteinization in vivo and in vitro, Mol. Cell. Endocrinol., 134, 59, 10.1016/S0303-7207(97)00173-1 · DOI
  32. Tong, 2011, Tupaia CD81, SR-BI, claudin-1, and occludin support hepatitis C virus infection, J. Virol., 85, 2793, 10.1128/JVI.01818-10 · DOI
  33. PrabhuDas, 2017, A consensus definitive classification of scavenger receptors and their roles in health and disease, J. Immunol., 198, 3775, 10.4049/jimmunol.1700373 · DOI
  34. Calvo, 1995, The CD36, CLA-1 (CD36L1), and LIMPII (CD36L2) gene family: cellular distribution, chromosomal location, and genetic evolution, Genomics., 25, 100, 10.1016/0888-7543(95)80114-2 · DOI
  35. Webb, 1997, Alternative forms of the scavenger receptor BI (SR-BI), J. Lipid Res., 38, 1490, 10.1016/S0022-2275(20)37431-9 · DOI
  36. Krieger, 1999, Charting the fate of the “good cholesterol”: identification and characterization of the high-density lipoprotein receptor SR-BI, Annu. Rev. Biochem., 68, 523, 10.1146/annurev.biochem.68.1.523 · DOI
  37. Rigotti, 2003, The role of the high-density lipoprotein receptor SR-BI in the lipid metabolism of endocrine and other tissues, Endocr. Rev., 24, 357, 10.1210/er.2001-0037 · DOI
  38. Connelly, 2004, Scavenger receptor BI: a scavenger receptor with a mission to transport high density lipoprotein lipids, Curr. Opin. Lipidol., 15, 287, 10.1097/00041433-200406000-00008 · DOI
  39. Silverstein, 2009, CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior, Sci. Signal., 2, re3, 10.1126/scisignal.272re3 · DOI · Paper page
  40. Gonzalez, 2014, Lysosomal integral membrane protein-2: a new player in lysosome-related pathology, Mol. Genet. Metab., 111, 84, 10.1016/j.ymgme.2013.12.005 · DOI
  41. Williams, 1999, Scavenger receptor BI and cholesterol trafficking, Curr. Opin. Lipidol., 10, 329, 10.1097/00041433-199908000-00007 · DOI
  42. Viñals, 2003, Identification of the N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SR-BI and assessment of their effects on HDL binding and selective lipid uptake, J. Biol. Chem., 278, 5325, 10.1074/jbc.M211073200 · DOI
  43. Webb, 1998, SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells, J. Biol. Chem., 273, 15241, 10.1074/jbc.273.24.15241 · DOI
  44. Babitt, 1997, Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae, J. Biol. Chem., 272, 13242, 10.1074/jbc.272.20.13242 · DOI
  45. Zani, 2015, Scavenger receptor structure and function in health and disease, Cells., 4, 178, 10.3390/cells4020178 · DOI
  46. Calvo, 1997, CLA-1 is an 85-kD plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins, Arterioscler. Thromb. Vasc. Biol., 17, 2341, 10.1161/01.ATV.17.11.2341 · DOI
  47. Ohgami, 2001, Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products, J. Biol. Chem., 276, 13348, 10.1074/jbc.M011613200 · DOI
  48. Marsche, 2002, Hypochlorite-modified high density lipoprotein, a high affinity ligand to scavenger receptor class B, type I, impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport, J. Biol. Chem., 277, 32172, 10.1074/jbc.M200503200 · DOI
  49. Marsche, 2003, Class B scavenger receptors CD36 and SR-BI are receptors for hypochlorite-modified low density lipoprotein, J. Biol. Chem., 278, 47562, 10.1074/jbc.M308428200 · DOI
  50. Xu, 1997, Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake, J. Lipid Res., 38, 1289, 10.1016/S0022-2275(20)37413-7 · DOI
  51. Li, 2002, Reconstituted discoidal ApoE-phospholipid particles are ligands for the scavenger receptor BI. The amino-terminal 1-165 domain of ApoE suffices for receptor binding, J. Biol. Chem., 277, 21149, 10.1074/jbc.M200658200 · DOI
  52. de Beer, 2001, Apolipoprotein A-II modulates the binding and selective lipid uptake of reconstituted high density lipoprotein by scavenger receptor BI, J. Biol. Chem., 276, 15832, 10.1074/jbc.M100228200 · DOI
  53. Phillips, 2013, New insights into the determination of HDL structure by apolipoproteins: Thematic review series: high density lipoprotein structure, function, and metabolism, J. Lipid Res., 54, 2034, 10.1194/jlr.R034025 · DOI
  54. Liadaki, 2000, Binding of high density lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger receptor class B type I. Effect of lipid association and APOA-I mutations on receptor binding, J. Biol. Chem., 275, 21262, 10.1074/jbc.M002310200 · DOI
  55. de Beer, 2001, Apolipoprotein A-I conformation markedly influences HDL interaction with scavenger receptor BI, J. Lipid Res., 42, 309, 10.1016/S0022-2275(20)31693-X · DOI
  56. Williams, 2000, Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic alpha-helix as a recognition motif, J. Biol. Chem., 275, 18897, 10.1074/jbc.M002411200 · DOI
  57. Pilon, 2000, Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake, Arterioscler. Thromb. Vasc. Biol., 20, 1074, 10.1161/01.ATV.20.4.1074 · DOI
  58. Rigotti, 1995, The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids, J. Biol. Chem., 270, 16221, 10.1074/jbc.270.27.16221 · DOI
  59. Cai, 2005, Serum amyloid A is a ligand for scavenger receptor class B type I and inhibits high density lipoprotein binding and selective lipid uptake, J. Biol. Chem., 280, 2954, 10.1074/jbc.M411555200 · DOI
  60. Kawasaki, 2002, Phosphatidylserine binding of class B scavenger receptor type I, a phagocytosis receptor of testicular Sertoli cells, J. Biol. Chem., 277, 27559, 10.1074/jbc.M202879200 · DOI
  61. Tsugita, 2017, SR-B1 is a silica receptor that mediates canonical inflammasome activation, Cell Reports., 18, 1298, 10.1016/j.celrep.2017.01.004 · DOI
  62. Ashraf, 2008, Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters, J. Biol. Chem., 283, 10408, 10.1074/jbc.M710474200 · DOI
  63. Gao, 2015, Analysis of relationship between oxidized phospholipid structure and interaction with the class B scavenger receptors, Methods Mol. Biol., 1208, 29, 10.1007/978-1-4939-1441-8_3 · DOI
  64. Vishnyakova, 2003, Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1, J. Biol. Chem., 278, 22771, 10.1074/jbc.M211032200 · DOI
  65. Bocharov, 2004, Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in THP-1 monocyte cells, J. Biol. Chem., 279, 36072, 10.1074/jbc.M314264200 · DOI
  66. Vishnyakova, 2006, CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells, Proc. Natl. Acad. Sci. USA., 103, 16888, 10.1073/pnas.0602126103 · DOI
  67. Fukasawa, 1996, SRB1, a class B scavenger receptor, recognizes both negatively charged liposomes and apoptotic cells, Exp. Cell Res., 222, 246, 10.1006/excr.1996.0030 · DOI
  68. Murao, 1997, Characterization of CLA-1, a human homologue of rodent scavenger receptor BI, as a receptor for high density lipoprotein and apoptotic thymocytes, J. Biol. Chem., 272, 17551, 10.1074/jbc.272.28.17551 · DOI
  69. Shiratsuchi, 1999, Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells, J. Biol. Chem., 274, 5901, 10.1074/jbc.274.9.5901 · DOI
  70. Svensson, 1999, Scavenger receptor class B type I in the rat ovary: possible role in high density lipoprotein cholesterol uptake and in the recognition of apoptotic granulosa cells, Endocrinology., 140, 2494, 10.1210/endo.140.6.6693 · DOI
  71. Imachi, 2000, Human scavenger receptor B1 is involved in recognition of apoptotic thymocytes by thymic nurse cells, Lab. Invest., 80, 263, 10.1038/labinvest.3780029 · DOI
  72. Herz, 2001, LRP: a multifunctional scavenger and signaling receptor, J. Clin. Invest., 108, 779, 10.1172/JCI200113992 · DOI · Paper page
  73. Neels, 1999, The second and fourth cluster of class A cysteine-rich repeats of the low density lipoprotein receptor-related protein share ligand-binding properties, J. Biol. Chem., 274, 31305, 10.1074/jbc.274.44.31305 · DOI · Paper page
  74. Provost, 2003, Expression of SR-BI receptor and StAR protein in rat ocular tissues, C. R. Biol., 326, 841, 10.1016/j.crvi.2003.09.001 · DOI
  75. Ji, 1999, Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile, J. Biol. Chem., 274, 33398, 10.1074/jbc.274.47.33398 · DOI
  76. Mardones, 2001, Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice, J. Lipid Res., 42, 170, 10.1016/S0022-2275(20)31676-X · DOI
  77. Yuan, 2013, Cooperation between hepatic cholesteryl ester hydrolase and scavenger receptor BI for hydrolysis of HDL-CE, J. Lipid Res., 54, 3078, 10.1194/jlr.M040998 · DOI
  78. Wiersma, 2009, Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice, Hepatology., 50, 1263, 10.1002/hep.23112 · DOI
  79. Temel, 1997, Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells, Proc. Natl. Acad. Sci. USA., 94, 13600, 10.1073/pnas.94.25.13600 · DOI
  80. Reaven, 1998, Expression and microvillar localization of scavenger receptor, class B, type I (a high density lipoprotein receptor) in luteinized and hormone-desensitized rat ovarian models, Endocrinology., 139, 2847, 10.1210/endo.139.6.6056 · DOI
  81. Azhar, 2002, Hormonal regulation of adrenal microvillar channel formation, J. Lipid Res., 43, 861, 10.1016/S0022-2275(20)30459-4 · DOI
  82. Connelly, 2003, SR-BI and cholesterol uptake into steroidogenic cells, Trends Endocrinol. Metab., 14, 467, 10.1016/j.tem.2003.10.002 · DOI
  83. Rao, 2003, Differential regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of SR-B1-mediated selective cholesteryl ester transport, Biol. Reprod., 68, 114, 10.1095/biolreprod.102.007518 · DOI
  84. Cao, 1997, Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1, J. Biol. Chem., 272, 33068, 10.1074/jbc.272.52.33068 · DOI
  85. Pal, 2016, Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease, Am. J. Physiol. Heart Circ. Physiol., 311, H1392, 10.1152/ajpheart.00463.2016 · DOI
  86. Reaven, 1988, Evidence for surface entrapment of cholesterol-rich lipoproteins in luteinized ovary, Arteriosclerosis., 8, 298, 10.1161/01.ATV.8.3.298 · DOI
  87. Reaven, 2001, Expression of scavenger receptor class B type 1 (SR-BI) promotes microvillar channel formation and selective cholesteryl ester transport in a heterologous reconstituted system, Proc. Natl. Acad. Sci. USA., 98, 1613, 10.1073/pnas.98.4.1613 · DOI
  88. Reaven, 2006, Consequences of over-expression of rat Scavenger Receptor, SR-BI, in an adrenal cell model, Nutr. Metab. (Lond.)., 3, 43, 10.1186/1743-7075-3-43 · DOI
  89. Williams, 2002, SR-BI is required for microvillar channel formation and the localization of HDL particles to the surface of adrenocortical cells in vivo, J. Lipid Res., 43, 544, 10.1016/S0022-2275(20)31483-8 · DOI
  90. Duggan, 2002, Expression of SR-BI (scavenger receptor class B type I) in turtle (Chrysemys picta) tissues and other nonmammalian vertebrates, J. Exp. Zool., 292, 430, 10.1002/jez.10067 · DOI
  91. Kleveland, 2006, Characterization of scavenger receptor class B, type I in Atlantic salmon (Salmo salar L.), Lipids., 41, 1017, 10.1007/s11745-006-5052-3 · DOI
  92. Ding, 2016, Scavenger receptor class B, type I, a CD36 related protein in Macrobrachium nipponense: characterization, RNA interference, and expression analysis with different dietary lipid sources, Int. J. Genomics., 2016, 6325927, 10.1155/2016/6325927 · DOI
  93. Nichols, 2008, The SNMP/CD36 gene family in Diptera, Hymenoptera and Coleoptera: Drosophila melanogaster, D. pseudoobscura, Anopheles gambiae, Aedes aegypti, Apis mellifera, and Tribolium castaneum, Insect Biochem. Mol. Biol., 38, 398, 10.1016/j.ibmb.2007.11.003 · DOI
  94. Vogt, 2009, The insect SNMP gene family, Insect Biochem. Mol. Biol., 39, 448, 10.1016/j.ibmb.2009.03.007 · DOI
  95. Herboso, 2011, Expression of the scavenger receptor class B type I (SR-BI) family in Drosophila melanogaster, Int. J. Dev. Biol., 55, 603, 10.1387/ijdb.103254lh · DOI
  96. Sakudoh, 2010, A CD36-related transmembrane protein is coordinated with an intracellular lipid-binding protein in selective carotenoid transport for cocoon coloration, J. Biol. Chem., 285, 7739, 10.1074/jbc.M109.074435 · DOI
  97. Lopez, 1999, Sterol regulatory element-binding protein-1a binds to cis elements in the promoter of the rat high density lipoprotein receptor SR-BI gene, Endocrinology., 140, 5669, 10.1210/endo.140.12.7220 · DOI
  98. Lopez, 1999, Steroidogenic factor-1 mediates cyclic 3′,5′-adenosine monophosphate regulation of the high density lipoprotein receptor, Endocrinology., 140, 3034, 10.1210/endo.140.7.6846 · DOI
  99. Ansari, 2013, MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo, Mol. Endocrinol., 27, 92, 10.1210/me.2012-1147 · DOI
  100. Murao, 2008, The transcriptional factor prolactin regulatory element-binding protein mediates the gene transcription of adrenal scavenger receptor class B type I via 3′,5′-cyclic adenosine 5′-monophosphate, Endocrinology., 149, 6103, 10.1210/en.2008-0380 · DOI
  101. Malerød, 2002, Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes, Biochem. Biophys. Res. Commun., 299, 916, 10.1016/S0006-291X(02)02760-2 · DOI
  102. Lopez, 2006, Activation of the rat scavenger receptor class B type I gene by PPARalpha, Mol. Cell. Endocrinol., 251, 67, 10.1016/j.mce.2006.02.011 · DOI
  103. Lopez, 2002, Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A, Endocrinology., 143, 2155, 10.1210/endo.143.6.8855 · DOI
  104. Shea-Eaton, 2001, Yin yang 1 protein negatively regulates high-density lipoprotein receptor gene transcription by disrupting binding of sterol regulatory element binding protein to the sterol regulatory element, Endocrinology., 142, 49, 10.1210/endo.142.1.7868 · DOI
  105. Lopez, 2001, DAX-1 represses the high-density lipoprotein receptor through interaction with positive regulators sterol regulatory element-binding protein-1a and steroidogenic factor-1, Endocrinology., 142, 5097, 10.1210/endo.142.12.8523 · DOI
  106. Sporstøl, 2005, Pregnane X receptor-agonists down-regulate hepatic ATP-binding cassette transporter A1 and scavenger receptor class B type I, Biochem. Biophys. Res. Commun., 331, 1533, 10.1016/j.bbrc.2005.04.071 · DOI
  107. Wang, 2013, MicroRNAs 185, 96, and 223 repress selective high-density lipoprotein cholesterol uptake through posttranscriptional inhibition, Mol. Cell. Biol., 33, 1956, 10.1128/MCB.01580-12 · DOI
  108. Hu, 2012, MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells, Mol. Cell. Biol., 32, 5035, 10.1128/MCB.01002-12 · DOI
  109. Sahoo, 2007, Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers, Biochim. Biophys. Acta., 1771, 807, 10.1016/j.bbalip.2006.03.003 · DOI
  110. Sahoo, 2007, Scavenger receptor class B, type I (SR-BI) homo-dimerizes via its C-terminal region: fluorescence resonance energy transfer analysis, Biochim. Biophys. Acta., 1771, 818, 10.1016/j.bbalip.2007.04.019 · DOI
  111. Gaidukov, 2011, Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport, J. Biol. Chem., 286, 18452, 10.1074/jbc.M111.229872 · DOI
  112. Landschulz, 1996, Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat, J. Clin. Invest., 98, 984, 10.1172/JCI118883 · DOI
  113. Reaven, 2004, Dimerization of the scavenger receptor class B type I: formation, function, and localization in diverse cells and tissues, J. Lipid Res., 45, 513, 10.1194/jlr.M300370-JLR200 · DOI
  114. Hu, 2011, Differential roles of cysteine residues in the cellular trafficking, dimerization, and function of the high-density lipoprotein receptor, SR-BI, Biochemistry., 50, 10860, 10.1021/bi201264y · DOI
  115. Kartz, 2014, SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport, Biochemistry., 53, 6173, 10.1021/bi500706x · DOI
  116. Papale, 2010, Extracellular hydrophobic regions in scavenger receptor BI play a key role in mediating HDL-cholesterol transport, Arch. Biochem. Biophys., 496, 132, 10.1016/j.abb.2010.02.011 · DOI
  117. Yu, 2011, Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity, Proc. Natl. Acad. Sci. USA., 108, 12243, 10.1073/pnas.1109078108 · DOI
  118. Guo, 2011, C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake, J. Lipid Res., 52, 2272, 10.1194/jlr.M019091 · DOI
  119. Papale, 2011, Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport, Biochemistry., 50, 6245, 10.1021/bi2005625 · DOI
  120. Yu, 2012, Contributions of a disulfide bond and a reduced cysteine side chain to the intrinsic activity of the high-density lipoprotein receptor SR-BI, Biochemistry., 51, 10044, 10.1021/bi301203x · DOI
  121. Neculai, 2013, Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36, Nature., 504, 172, 10.1038/nature12684 · DOI
  122. Rasmussen, 1998, Assignment of disulfide bridges in bovine CD36, Eur. J. Biochem., 257, 488, 10.1046/j.1432-1327.1998.2570488.x · DOI
  123. Conrad, 2017, Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies, Nat. Commun., 8, 1908, 10.1038/s41467-017-02044-8 · DOI
  124. Chadwick, 2015, Expression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis, Protein Expr. Purif., 107, 35, 10.1016/j.pep.2014.11.001 · DOI
  125. Parathath, 2004, Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester, J. Biol. Chem., 279, 24976, 10.1074/jbc.M402435200 · DOI
  126. Shen, 2014, Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions, Metabolism., 63, 875, 10.1016/j.metabol.2014.03.011 · DOI
  127. Shen, 2017, SR-B1: a unique multifunctional receptor for cholesterol influx and efflux, Annu. Rev. Physiol., 80, 95, 10.1146/annurev-physiol-021317-121550 · DOI
  128. Shen, 2016, ACTH regulation of adrenal SR-B1, Front. Endocrinol. (Lausanne)., 7, 42, 10.3389/fendo.2016.00042 · DOI
  129. Gu, 1998, The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain, J. Biol. Chem., 273, 26338, 10.1074/jbc.273.41.26338 · DOI
  130. Connelly, 1999, Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake, J. Biol. Chem., 274, 41, 10.1074/jbc.274.1.41 · DOI
  131. Liu, 2002, J. Biol. Chem., 277, 21576, 10.1074/jbc.M112103200 · DOI
  132. Temel, 2002, Apolipoprotein A-I is necessary for the in vivo formation of high density lipoprotein competent for scavenger receptor BI-mediated cholesteryl ester-selective uptake, J. Biol. Chem., 277, 26565, 10.1074/jbc.M203014200 · DOI
  133. Temel, 2003, Enhancement of scavenger receptor class B type I-mediated selective cholesteryl ester uptake from apoA-I(−/−) high density lipoprotein (HDL) by apolipoprotein A-I requires HDL reorganization by lecithin cholesterol acyltransferase, J. Biol. Chem., 278, 4792, 10.1074/jbc.M208160200 · DOI
  134. Nieland, 2002, Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI, Proc. Natl. Acad. Sci. USA., 99, 15422, 10.1073/pnas.222421399 · DOI
  135. Hoekstra, 2017, SR-BI as target in atherosclerosis and cardiovascular disease - a comprehensive appraisal of the cellular functions of SR-BI in physiology and disease, Atherosclerosis., 258, 153, 10.1016/j.atherosclerosis.2017.01.034 · DOI
  136. Rodrigueza, 1999, Mechanism of scavenger receptor class B type I-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cells, J. Biol. Chem., 274, 20344, 10.1074/jbc.274.29.20344 · DOI
  137. Gomez-Diaz, 2016, A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism, Nat. Commun., 7, 11866, 10.1038/ncomms11866 · DOI
  138. Phillips, 2014, Molecular mechanisms of cellular cholesterol efflux, J. Biol. Chem., 289, 24020, 10.1074/jbc.R114.583658 · DOI
  139. Sparrow, 1990, Cholesterol esters selectively taken up from high-density lipoproteins are hydrolyzed extralysosomally, Biochim. Biophys. Acta., 1043, 203, 10.1016/0005-2760(90)90297-B · DOI
  140. DeLamatre, 1991, Evidence for extralysosomal hydrolysis of high-density lipoprotein cholesteryl esters in rat hepatoma cells (Fu5AH): a model for delivery of high-density lipoprotein cholesterol, J. Cell. Physiol., 146, 18, 10.1002/jcp.1041460104 · DOI
  141. Shimada, 1994, Increase in neutral cholesteryl ester hydrolase activity produced by extralysosomal hydrolysis of high-density lipoprotein cholesteryl esters in rat hepatoma cells (H-35), Biochim. Biophys. Acta., 1215, 126, 10.1016/0005-2760(94)90101-5 · DOI
  142. Connelly, 2003, SR-BI-directed HDL-cholesteryl ester hydrolysis, J. Lipid Res., 44, 331, 10.1194/jlr.M200186-JLR200 · DOI
  143. Kraemer, 2004, Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis, Mol. Endocrinol., 18, 549, 10.1210/me.2003-0179 · DOI
  144. Thuahnai, 2001, Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor, J. Biol. Chem., 276, 43801, 10.1074/jbc.M106695200 · DOI
  145. Yancey, 2003, Importance of different pathways of cellular cholesterol efflux, Arterioscler. Thromb. Vasc. Biol., 23, 712, 10.1161/01.ATV.0000057572.97137.DD · DOI
  146. Ji, 1997, Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux, J. Biol. Chem., 272, 20982, 10.1074/jbc.272.34.20982 · DOI
  147. Kent, 2011, Scavenger receptor class B member 1 protein: hepatic regulation and its effects on lipids, reverse cholesterol transport, and atherosclerosis, Hepat. Med., 3, 29
  148. Kellner-Weibel, 2000, Expression of scavenger receptor BI in COS-7 cells alters cholesterol content and distribution, Biochemistry., 39, 221, 10.1021/bi991666c · DOI
  149. Silver, 2001, The cellular biology of scavenger receptor class B type I, Curr. Opin. Lipidol., 12, 497, 10.1097/00041433-200110000-00004 · DOI
  150. Jian, 1998, Scavenger receptor class B type I as a mediator of cellular cholesterol efflux to lipoproteins and phospholipid acceptors, J. Biol. Chem., 273, 5599, 10.1074/jbc.273.10.5599 · DOI
  151. de la Llera-Moya, 1999, Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface, J. Lipid Res., 40, 575, 10.1016/S0022-2275(20)32462-7 · DOI
  152. Gu, 2000, Scavenger receptor class B, type I-mediated [3H]cholesterol efflux to high and low density lipoproteins is dependent on lipoprotein binding to the receptor, J. Biol. Chem., 275, 29993, 10.1074/jbc.275.39.29993 · DOI
  153. Oram, 2000, ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages, J. Biol. Chem., 275, 34508, 10.1074/jbc.M006738200 · DOI
  154. Sankaranarayanan, 2009, Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux, J. Lipid Res., 50, 275, 10.1194/jlr.M800362-JLR200 · DOI
  155. Rigotti, 1997, A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism, Proc. Natl. Acad. Sci. USA., 94, 12610, 10.1073/pnas.94.23.12610 · DOI
  156. Varban, 1998, Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol, Proc. Natl. Acad. Sci. USA., 95, 4619, 10.1073/pnas.95.8.4619 · DOI
  157. Ueda, 1999, Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice, J. Biol. Chem., 274, 7165, 10.1074/jbc.274.11.7165 · DOI
  158. Yesilaltay, 2006, Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertility, Endocrinology., 147, 1577, 10.1210/en.2005-1286 · DOI
  159. Arai, 1999, Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene, J. Biol. Chem., 274, 2366, 10.1074/jbc.274.4.2366 · DOI
  160. Kozarsky, 2000, Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse, Arterioscler. Thromb. Vasc. Biol., 20, 721, 10.1161/01.ATV.20.3.721 · DOI
  161. Ueda, 2000, Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics, J. Biol. Chem., 275, 20368, 10.1074/jbc.M000730200 · DOI
  162. Zhang, 2005, Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo, J. Clin. Invest., 115, 2870, 10.1172/JCI25327 · DOI · Paper page
  163. Trigatti, 1999, Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology, Proc. Natl. Acad. Sci. USA., 96, 9322, 10.1073/pnas.96.16.9322 · DOI
  164. Huszar, 2000, Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1, Arterioscler. Thromb. Vasc. Biol., 20, 1068, 10.1161/01.ATV.20.4.1068 · DOI
  165. Covey, 2003, Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptor-negative mice involves its expression in bone marrow-derived cells, Arterioscler. Thromb. Vasc. Biol., 23, 1589, 10.1161/01.ATV.0000083343.19940.A0 · DOI
  166. Van Eck, 2003, Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver, J. Biol. Chem., 278, 23699, 10.1074/jbc.M211233200 · DOI
  167. Linton, 2017, SR-BI: a multifunctional receptor in cholesterol homeostasis and atherosclerosis, Trends Endocrinol. Metab., 28, 461, 10.1016/j.tem.2017.02.001 · DOI
  168. Armstrong, 2015, A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis, Cardiovasc. Res., 108, 268, 10.1093/cvr/cvv218 · DOI
  169. Yates, 2011, Clinical impact of scavenger receptor class B type I gene polymorphisms on human female fertility, Hum. Reprod., 26, 1910, 10.1093/humrep/der124 · DOI
  170. Holm, 2002, Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI, Blood., 99, 1817, 10.1182/blood.V99.5.1817.h8001817_1817_1824 · DOI
  171. Zheng, 2014, Scavenger receptor class B type I and immune dysfunctions, Curr. Opin. Endocrinol. Diabetes Obes., 21, 121, 10.1097/MED.0000000000000046 · DOI
  172. Burlone, 2009, Hepatitis C virus cell entry: role of lipoproteins and cellular receptors, J. Gen. Virol., 90, 1055, 10.1099/vir.0.008300-0 · DOI
  173. Li, 2013, Human apolipoprotein A-I is associated with dengue virus and enhances virus infection through SR-BI, PLoS One., 8, e70390, 10.1371/journal.pone.0070390 · DOI
  174. Baranova, 2016, Human SR-BI and SR-BII potentiate lipopolysaccharide-induced inflammation and acute liver and kidney injury in mice, J. Immunol., 196, 3135, 10.4049/jimmunol.1501709 · DOI
  175. Yuhanna, 2001, High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase, Nat. Med., 7, 853, 10.1038/89986 · DOI
  176. Zhu, 2008, The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity, Circ. Res., 102, 480, 10.1161/CIRCRESAHA.107.159079 · DOI
  177. Mineo, 2003, High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases, J. Biol. Chem., 278, 9142, 10.1074/jbc.M211394200 · DOI
  178. Saddar, 2013, Scavenger receptor class B type I is a plasma membrane cholesterol sensor, Circ. Res., 112, 140, 10.1161/CIRCRESAHA.112.280081 · DOI
  179. Morel, 2018, Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells, Biochim. Biophys. Acta., 1863, 199, 10.1016/j.bbalip.2017.11.009 · DOI
  180. Baranova, 2005, Serum amyloid A binding to CLA-1 (CD36 and LIMPII analogous-1) mediates serum amyloid A protein-induced activation of ERK1/2 and p38 mitogen-activated protein kinases, J. Biol. Chem., 280, 8031, 10.1074/jbc.M405009200 · DOI
  181. van der Westhuyzen, 2005, Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I, J. Biol. Chem., 280, 35890, 10.1074/jbc.M505685200 · DOI
  182. Lee, 2017, S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization, J. Lipid Res., 58, 325, 10.1194/jlr.M070706 · DOI
  183. Liu, 2016, ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner, J. Physiol. Biochem., 72, 657, 10.1007/s13105-016-0504-6 · DOI
  184. Song, 2015, Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase, Cell. Signal., 27, 1873, 10.1016/j.cellsig.2015.05.003 · DOI
  185. Zhu, 2009, Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells, J. Biol. Chem., 284, 22878, 10.1074/jbc.M109.018580 · DOI
  186. Trigatti, 2003, Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis, Arterioscler. Thromb. Vasc. Biol., 23, 1732, 10.1161/01.ATV.0000091363.28501.84 · DOI
  187. Leiva, 2011, Mechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism, Atherosclerosis., 217, 299, 10.1016/j.atherosclerosis.2011.05.036 · DOI
  188. Donowitz, 2005, NHERF family and NHE3 regulation, J. Physiol., 567, 3, 10.1113/jphysiol.2005.090399 · DOI
  189. Ikemoto, 2000, Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I, Proc. Natl. Acad. Sci. USA., 97, 6538, 10.1073/pnas.100114397 · DOI
  190. Silver, 2002, A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver, J. Biol. Chem., 277, 34042, 10.1074/jbc.M206584200 · DOI
  191. Kocher, 2003, Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism, J. Biol. Chem., 278, 52820, 10.1074/jbc.M310482200 · DOI
  192. Kocher, 2010, In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1, J. Biol. Chem., 285, 34999, 10.1074/jbc.M110.164418 · DOI
  193. Fenske, 2009, Normal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1, J. Biol. Chem., 284, 5797, 10.1074/jbc.M808211200 · DOI
  194. Kocher, 2011, Identification of the PDZ3 domain of the adaptor protein PDZK1 as a second, physiologically functional binding site for the C terminus of the high density lipoprotein receptor scavenger receptor class B type I, J. Biol. Chem., 286, 25171, 10.1074/jbc.M111.242362 · DOI
  195. Tsukamoto, 2013, Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI), J. Biol. Chem., 288, 19845, 10.1074/jbc.M113.460170 · DOI
  196. Hu, 2013, Regulation of expression and function of scavenger receptor class B, type I (SR-BI) by Na+/H+ exchanger regulatory factors (NHERFs), J. Biol. Chem., 288, 11416, 10.1074/jbc.M112.437368 · DOI
  197. Kocher, 1995, Identification of a novel gene, selectively up-regulated in human carcinomas, using the differential display technique, Clin. Cancer Res., 1, 1209
  198. Silver, 2003, Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels, J. Biol. Chem., 278, 28528, 10.1074/jbc.M304109200 · DOI
  199. Green, 1991, Selective uptake of cholesteryl esters from low density lipoproteins in vitro and in vivo, J. Lipid Res., 32, 667, 10.1016/S0022-2275(20)42054-1 · DOI
  200. Leitersdorf, 1984, Uptake of rat plasma HDL subfractions labeled with [3H]cholesteryl linoleyl ether or with 125I by cultured rat hepatocytes and adrenal cells, Biochim. Biophys. Acta., 796, 72, 10.1016/0005-2760(84)90240-6 · DOI

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Metadata

Authors
Shen, W.-J., Asthana, S., Kraemer, F. B., & Azhar, S.
ORCID
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
2018
Volume
59
Issue
7
Pages
1114-1131
ISSN
0022-2275
DOI
10.1194/jlr.r083121
Cited by
148
References
8
Language
en
Licence
Funders
  • National Heart, Lung, and Blood Institute (R56HL122773)
  • VA Biomedical Laboratory Research and Development (2I01BX001923, IK6BX004200, 10BX000398)

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