Cited by 1,752Cancer survivorship and careHealth Education and ValidationHealth Systems, Economic Evaluations, Quality of Life

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument.

Brady, M J, Cella, D F, Mo, F, Bonomi, A E, Tulsky, D S, Lloyd, S R, Deasy, S, Cobleigh, M, Shiomoto, G·1997·Journal of Clinical Oncology

DOI 10.1200/jco.1997.15.3.974

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Abstract

PURPOSE: This is the first published report on the validation of the Functional Assessment of Cancer Therapy-Breast (FACT-B), a 44-item self-report instrument designed to measure multidimensional quality of life (QL) in patients with breast cancer. The FACT-B consists of the FACT-General (FACT-G) plus the Breast Cancer Subscale (BCS), which complements the general scale with items specific to QL in breast cancer. The FACT-B was developed with an emphasis on patients' values and brevity and is available in nine languages. METHODS AND RESULTS: Two validation samples were used for this report. The first (n = 47) was tested twice over a 2-month period to assess sensitivity to change. Significant sensitivity to change in performance status rating (PSR) was demonstrated for the FACT-B total score, the Physical Well-Being (PWB) subscale, the Functional Well-Being (FWB) subscale, and the BCS. Sensitivity to change in QL as measured by the Functional Living Index-Cancer (FLIC) was documented in the FACT-B total score, PWB, FWB, and Emotional Well-Being (EWB). Additional validity and reliability data were obtained from a larger sample (n = 295). The alpha coefficient (internal consistency) for the FACT-B total score was high (alpha = .90), with subscale alpha coefficients ranging from .63 to .86. Evidence supported test-retest reliability, as well as convergent, divergent, and known groups validity. CONCLUSION: The FACT-B is appropriate for use in oncology clinical trials, as well as in clinical practice. It demonstrates ease of administration, brevity, reliability, validity, and sensitivity to change.

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The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology
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The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and Clinical Tests of Validity in Measuring Physical and Mental Health Constructs
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The functional assessment of cancer therapy scale: development and validation of the general measure
Cella, D. F., Tulsky, D. S., Gray, G., Sarafian, B., Linn, E., Bonomi, A., Silberman, M., Yellen, S. B., Winicour, P., & Brannon, J. (1993) · Journal of Clinical Oncology · doi:10.1200/jco.1993.11.3.570 · Cited by 6,020
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“[14] ranged from 0.”
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Comparison of the measurement properties between a short and generic instrument, the 5-level EuroQoL Group’s 5-dimension (EQ-5D-5L) questionnaire, and a longer and disease-specific instrument, the Functional Assessment of Cancer Therapy—Breast (FACT-B), in Asian breast cancer patients
Lee, C. F., Luo, N., Ng, R. C. H., Wong, N. S., Yap, Y. S., Lo, S. K., Chia, W. K., Yee, A., Krishna, L. K. R., Wong, C., et al. (2012) · Quality of Life Research · doi:10.1007/s11136-012-0291-7 · Cited by 41
“Figure 2 plots the EQ-5D-5L and FACT-B scores at follow-up against baseline.”
MethodInfluential
The impact of literacy on health-related quality of life measurement and outcomes in cancer outpatients
Hahn, E. A., Cella, D. F., Dobrez, D. G., Weiss, B. D., Du, H., Lai, J., Victorson, D. E., & Garcia, S. F. (2006) · Quality of Life Research · doi:10.1007/s11136-006-9128-6 · Cited by 41
“It has established reliability and validity, including sensitivity to change [28-32].”
BackgroundSelf-citation
Use of an electronic patient-reported outcome measurement system to improve distress management in oncology
Smith, S. K., Rowe, K., & Abernethy, A. P. (2013) · Palliative & Supportive Care · doi:10.1017/s1478951513000345 · Cited by 41
“…the ePRO system was supplemented with additional survey instruments such as the Functional Assessment of Cancer Therapy General-Breast scale (FACT-B; Brady et al., 1997) in order to add the quality of life (QOL), psychological, and other PRO information needed to support programmatic evaluation.”
Method
Feasibility of a psychosocial and patient navigation intervention to improve access to treatment among underserved breast cancer patients
Madore, S., Kilbourn, K. M., Valverde, P., Borrayo, E. A., & Raich, P. C. (2014) · Supportive Care in Cancer · doi:10.1007/s00520-014-2176-5 · Cited by 41
“Quality of life was measured using The Functional Assessment of Cancer Therapy for Breast Cancer (FACT-B), which is a validated 44-item selfreport measure designed to measure multidimensional quality of life in patients with breast cancer [34, 35].”
Method
Breast Cancer Among Asian Americans: Is Acculturation Related to Health-Related Quality of Life?
Kim, J., Ashing‐Giwa, K. T., Singer, M. K., & Tejero, J. S. (2006) · Oncology nursing forum · doi:10.1188/06.onf.e90-e99 · Cited by 41
“High reliability of the FACT-G subscales (part of FACT-B) has been reported for the English, Spanish, Chinese, and Korean versions (Brady et al., 1997; Dapueto et al., 2003; Lee, Chun, Kang, & Lee, 2004; Yoo et al., 2005; Yu et al., 2000).”
BackgroundMethodResultInfluential
Assessment of the measurement properties of quality of life questionnaires in Brazilian women with breast cancer
Oliveira, I. S., Costa, L. C. M., Manzoni, A. C. T., & Cabral, C. M. N. (2014) · Brazilian Journal of Physical Therapy · doi:10.1590/bjpt-rbf.2014.0045 · Cited by 41
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Gall, T. L., & Bilodeau, C. (2017) · Psychology and Health · doi:10.1080/08870446.2017.1293270 · Cited by 43
“The functional assessment of cancer therapy – breast (FACT-B) is a measure of health-related quality of life specific to breast cancer (Brady et al., 1997).”
Background
Quality of life of elderly patients with solid tumours undergoing adjuvant cancer therapy: a systematic review
Cheng, K. K. F., Lim, E. Y.-T., & Kanesvaran, R. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-018101 · Cited by 42
Nuevo Amanecer‐II : Results of a randomized controlled trial of a community‐based participatory, peer‐delivered stress management intervention for rural Latina breast cancer survivors
Nápoles, A. M., Santoyo‐Olsson, J., Stewart, A. L., Ortíz, C., Samayoa, C., Torres‐Nguyen, A., Palomino, H., Coleman, L., Urias, A., Gonzalez, N., et al. (2020) · Psycho-Oncology · doi:10.1002/pon.5481 · Cited by 40
“Breast cancer-specific quality of life scales = FACT-B scales.(23) Depressive symptoms = PHQ-8.”
Background
Cost-effectiveness of MR-mammography vs. conventional mammography in screening patients at intermediate risk of breast cancer - A model-based economic evaluation
Kaiser, C. G., Dietzel, M., Vág, T., & Froelich, M. F. (2020) · European Journal of Radiology · doi:10.1016/j.ejrad.2020.109355 · Cited by 41
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“This tool is a sensitive measure for evaluating physical, functional, social and emotional well-being and comprises the FACT-G ‘general’ QoL tool for cancer patients plus the Breast Cancer Subscale (Cella et al, 1993; Brady et al, 1997).”
Method
Holistic Healing for Women with Breast Cancer through a Mind, Body, and Spirit Self-Empowerment Program
Kinney, C. K., Rodgers, D., Nash, K. A., & Bray, C. O. (2003) · Journal of Holistic Nursing · doi:10.1177/0898010103254919 · Cited by 42
“Brady et al. (1997) reported internal consistency reliability estimates with coefficient α = .”
Subjective and Objective Assessment of Edema during Adjuvant Chemotherapy for Breast Cancer Using Taxane-Containing Regimens in a Randomized Controlled Trial: The National Surgical Adjuvant Study of Breast Cancer 02
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“LACE used the Functional Assessment of Cancer Therapy—Breast (FACTB) [40] to asses QOL at the baseline and follow-up surveys.”
Method
Examining health-related quality of life patterns in women with breast cancer
Pinheiro, L. C., Tan, X. M., Olshan, A. F., Wheeler, S. B., Reeder-Hayes, K. E., Samuel, C. A., & Reeve, B. B. (2017) · Quality of Life Research · doi:10.1007/s11136-017-1533-5 · Cited by 40
“The FACT-B has been psychometrically validated and shown to be sensitive to changes over time in women with BC [26].”
BackgroundMethod
Changes in sexual problems over time in women with and without early-stage breast cancer
Pérez, M., Liu, Y., Schootman, M., Aft, R., Schechtman, K. B., Gillanders, W. E., & Jeffe, D. B. (2010) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3181d5dd26 · Cited by 40
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Breast volume replacement using the latissimus dorsi miniflap
Nano, M. T., Gill, P. G., Kollias, J., & Bochner, M. A. (2004) · ANZ Journal of Surgery · doi:10.1046/j.1445-2197.2003.02917.x · Cited by 40
A Randomized Phase II Trial of Two Schedules of Docetaxel in Elderly or Poor Performance Status Patients with Advanced Non-small Cell Lung Cancer
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Stress Reactivity, Health Behaviors, and Compliance to Medical Care in Breast Cancer Survivors
Karvinen, K. H., Murray, N. P., Arastu, H. H., & Allison, R. R. (2013) · Oncology nursing forum · doi:10.1188/13.onf.149-156 · Cited by 39
“Quality of life: The Functional Assessment of Cancer Therapy–Breast (FACT-B) scale (Brady et al., 1997; Cella et al., 1993) was used to measure QOL.”
BackgroundMethodInfluential
Effects of Resilience, Post-traumatic Stress Disorder on the Quality of Life in Patients with Breast Cancer
Ha, B. Y., Jung, E., & Choi, S. Y. (2014) · Korean journal of women health nursing/Yeoseong geon'gang ganho hag'hoeji/Yeoseong geon-gang ganho hakoeji · doi:10.4069/kjwhn.2014.20.1.83 · Cited by 39
“삶의 질 측정도구는 Brady 등[18]이 개발한 Functional Assessment of Cancer Therapy-Breast Cancer Version 4 (FACT-B)의 한국어판 번역본을 승인받아 사용하였다.”
Effects of yoga on arm volume among women with breast cancer related lymphedema: A pilot study
Fisher, M. I., Donahoe-Fillmore, B., Leach, L. M., O’Malley, C., Paeplow, C., Prescott, T., & Merriman, H. L. (2014) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2014.02.006 · Cited by 43
“The FACT-B is a 36 item QOL questionnaire for BCS with good construct validity (r = .90) and test-retest reliability (ICC = .88) (Brady et al 1997).”
Method
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Maratia, S., Cedillo, S., & Rejas, J. (2016) · Quality of Life Research · doi:10.1007/s11136-016-1284-8 · Cited by 39
“As a first step, some of the disease-specific breast cancer HRQoL instruments were found by reviewing the online library of existing PRO instruments Patient-Reported Outcomes and Quality of Life Database (PROQOLID) [14], the websites of three cancer research groups: European Organisation for Research and Treatment of…”
Background
Development of a Japanese version of the BREAST-Q and the traditional psychometric test of the mastectomy module for the assessment of HRQOL and patient satisfaction following breast surgery
Saiga, M., Taira, N., Kimata, Y., Watanabe, S., Mukai, Y., Shimozuma, K., Mizoo, T., Nogami, T., Iwamoto, T., Motoki, T., et al. (2016) · Breast Cancer · doi:10.1007/s12282-016-0703-6 · Cited by 39
The Functional Impact of Breast Reconstruction: An Overview and Update
Nelson, J. A., Lee, I. T., & Disa, J. J. (2018) · Plastic & Reconstructive Surgery Global Open · doi:10.1097/gox.0000000000001640 · Cited by 39
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Longo, D. R., Ge, B., Radina, M. E., Greiner, A. K., Williams, C. D., Longo, G. S., Mouzon, D. M., Natale‐Pereira, A., & Salas‐Lopez, D. (2009) · Journal of Communications In Healthcare · doi:10.1179/cih.2009.2.2.184 · Cited by 39
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“The psychometric properties of the FACT scales are well documented [32,33] and have been found appropriate for use in cancer clinical trials.”
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Conner-Spady, B. L., Cumming, C. E., Nabholtz, J., Jacobs, P., & Stewart, D. A. (2001) · Quality of Life Research · doi:10.1023/a:1013018218360 · Cited by 39
Qualitative Development and Content Validity of the Non–small Cell Lung Cancer Symptom Assessment Questionnaire (NSCLC-SAQ), A Patient-reported Outcome Instrument
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Efficacy and safety of rechallenge treatment with gefitinib in patients with advanced non-small cell lung cancer
Cappuzzo, F., Morabito, A., Normanno, N., Bidoli, P., Conte, A. D., Giannetta, L. G., Montanino, A., Mazzoni, F., Buosi, R., Burgio, M. A., et al. (2016) · Lung Cancer · doi:10.1016/j.lungcan.2016.06.008 · Cited by 39
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“Finally, fear of death is also part of patients’ stress (Brady et al., 1997).”
Background
The reliability and validity of Lymphedema Quality of Life Questionnaire-Arm in Turkish patients with upper limb lymphedema related with breast cancer
Borman, P. (2018) · Turkish Journal of Physical Medicine and Rehabilitation · doi:10.5606/tftrd.2018.2843 · Cited by 38
“In conclusion, the Turkish translated version of LYMQOL-Arm is a valid and reliable tool for the assessment of the QoL in patients with BCRL.”
Influential
Can Counseling Add Value to an Exercise Intervention for Improving Quality of Life in Breast Cancer Survivors? A Feasibility Study
Naumann, F., Martin, E., Philpott, M., Smith, C., Groff, D. G., & Battaglini, C. L. (2011) · The Journal of Supportive Oncology · doi:10.1016/j.suponc.2011.09.004 · Cited by 38
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Grimison, P., & Stockler, M. R. (2007) · Expert Review of Anticancer Therapy · doi:10.1586/14737140.7.8.1123 · Cited by 38
¡Cocinar Para Su Salud! Development of a Culturally Based Nutrition Education Curriculum for Hispanic Breast Cancer Survivors Using a Theory-Driven Procedural Model
Aycinena, A. C., Jennings, K.-A., Gaffney, A. O., Koch, P. A., Contento, I. R., Gonzalez, M., Guidon, E., Karmally, W., Hershman, D. L., & Greenlee, H. (2016) · Health Education & Behavior · doi:10.1177/1090198116642236 · Cited by 38
“Questions were based on previously validated questionnaires (Brady et al., 1997; Contento, 2015; Gotay et al., 2007; Wallston, Stein, & Smith, 1994; Weiss et al., 2005; Zigmond & Snaith, 1983).”
Method
Effect of a Nurse Navigation Intervention on Mental Symptoms in Patients With Psychological Vulnerability and Breast Cancer
Bidstrup, P., Johansen, C., Kroman, N., Belmonte, F., Duriaud, H., Dalton, S., Andersen, K., & Mertz, B. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.19591 · Cited by 38
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Pinto, B. M., Stein, K., & DUNSIGER, S. I. (2015) · Psycho-Oncology · doi:10.1002/pon.3884 · Cited by 38
“Functional Assessment of Cancer Therapy Scale for Breast Cancer (FACT-B) is a 55-item scale that assesses QOL and is reliable and valid [26].”
Background
Quality of life and symptoms in male breast cancer survivors
Ruddy, K. J., Giobbie‐Hurder, A., Giordano, S. H., Goldfarb, S. B., Kereakoglow, S., Winer, E. P., & Partridge, A. H. (2013) · The Breast · doi:10.1016/j.breast.2012.12.014 · Cited by 37
A Brief Symptom Index for Advanced Lung Cancer
Yount, S., Beaumont, J. L., Rosenbloom, S. K., Cella, D. F., Patel, J. D., Hensing, T. A., Jacobsen, P. B., Syrjala, K. L., & Abernethy, A. P. (2011) · Clinical Lung Cancer · doi:10.1016/j.cllc.2011.03.033 · Cited by 37
Self-citation
Supportive Care in Lung Cancer: Milestones Over the Past 40 Years
Molassiotis, A., Uyterlinde, W., Hollen, P. J., Sarna, L. P., Palmer, P. N., & Krishnasamy, M. (2014) · Journal of Thoracic Oncology · doi:10.1097/jto.0000000000000407 · Cited by 36
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Carolan, C. M., Smith, A., & Forbat, L. (2015) · Palliative Medicine · doi:10.1177/0269216315575680 · Cited by 38
A phase 3 tRial comparing capecitabinE in combination with SorafenIb or pLacebo for treatment of locally advanced or metastatIc HER2-Negative breast CancEr (the RESILIENCE study): study protocol for a randomized controlled trial
Baselga, J. M., Costa, F. P., Gómez, H., Hudis, C. A., Rapoport, B. L., Roche, H. H., Schwartzberg, L. S., Petrenciuc, O., Shan, M., & Gradishar, W. J. (2013) · Trials · doi:10.1186/1745-6215-14-228 · Cited by 37
“Patient-reported outcomes (PROs) include an evaluation of breast cancer symptoms using the Functional Assessment of Cancer Therapy-Breast Symptom Index (8 items) (FBSI-8 questionnaire) [38,39] and health-related quality of life (HRQoL) using the EuroQoL 5-Dimension Questionnaire (EQ-5D) [40].”
Method
Mapping the FACT-B Instrument to EQ-5D-3L in Patients with Breast Cancer Using Adjusted Limited Dependent Variable Mixture Models versus Response Mapping
Gray, L. A., Wailoo, A., & Alava, M. H. (2018) · Value in Health · doi:10.1016/j.jval.2018.06.006 · Cited by 37
An Electronic Patient-Reported Outcome Tool for the FACT-B (Functional Assessment of Cancer Therapy-Breast) Questionnaire for Measuring the Health-Related Quality of Life in Patients With Breast Cancer: Reliability Study
Matthies, L. M., Taran, F., Keilmann, L., Schneeweiß, A., Simoes, E., Hartkopf, A. D., Sokolov, A. N., Walter, C. B., Sickenberger, N., Wallwiener, S., et al. (2018) · Journal of Medical Internet Research · doi:10.2196/10004 · Cited by 37
Assessing the effect of patient navigator assistance for psychosocial support services on health‐related quality of life in a randomized clinical trial in Latino breast, prostate, and colorectal cancer survivors
Ramírez, A. G., Choi, B. Y., Muñoz, E., Perez, A., Gallion, K. J., Moreno, P. I., & Penedo, F. J. (2019) · Cancer · doi:10.1002/cncr.32626 · Cited by 37
The Women’s Circle of Health Follow-Up Study: a population-based longitudinal study of Black breast cancer survivors in New Jersey
Bandera, E. V., Demissie, K., Qin, B., Llanos, A. A. M., Lin, Y., Xu, B., Pawlish, K. S., Plascak, J. J., Tsui, J., Omilian, A. R., et al. (2020) · Journal of Cancer Survivorship · doi:10.1007/s11764-019-00849-8 · Cited by 37
Full population results from the core phase of CompLEEment-1, a phase 3b study of ribociclib plus letrozole as first-line therapy for advanced breast cancer in an expanded population
Laurentiis, M. D., Borštnar, S., Campone, M., Warner, E., Bofill, J. S., Jacot, W., Dent, S. F., Martín, M., Ring, A. E., Cottu, P. H., et al. (2021) · Breast Cancer Research and Treatment · doi:10.1007/s10549-021-06334-0 · Cited by 39
Quality of Life and Patient-reported Outcomes in the Older Breast Cancer Patient
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“18% was distributed in 10 factors, with the items well interrelated as the English version.(27)”
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Background
Rapid improvement of depression and quality of life with escitalopram treatment in outpatients with breast cancer: A 12-week, open-label prospective trial
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Background
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“This study utilized a flush diary, the Hot Flushes and Night Sweats Questionnaire (HFNSQ), Functional Assessment of Cancer Therapy with Endocrine Subscale (FACT-ES) and Spielberger State/Trait Anxiety Index (STAI) as the main outcome measures.”
MethodInfluential
Mental adjustment to cancer and quality of life among women living with breast cancer in Ghana
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“90.(36) Some studies conducted in Africa have found the scale to be reliable with domain-specific values ranging between .”
Background
Initial validation of a scale to measure purposelessness, understimulation, and boredom in cancer patients: toward a redefinition of depression in advanced disease
PASSIK, S. D., INMAN, A., KIRSH, K., THEOBALD, D., & DICKERSON, P. (2003) · Palliative and Supportive Care · doi:10.1017/s1478951503030062 · Cited by 35
“The measure has been shown to yield adequate to high internal consistency, exhibiting coefficient alphas ranging from 0.63 to 0.86 on the subscales and 0.90 to 0.95 for the total scale ~Cella et al., 1995; Brady et al., 1997!.”
BackgroundInfluential
Longitudinal assessment of distress and quality of life in the early stages of breast cancer treatment
Costa‐Requena, G., Rodríguez, A., & Fernández‐Ortega, P. (2013) · Scandinavian Journal of Caring Sciences · doi:10.1111/j.1471-6712.2012.01003.x · Cited by 48
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Integration of patient-reported outcome measures with key clinical outcomes after immediate latissimus dorsi breast reconstruction and adjuvant treatment
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“Participant characteristics and treatment-related data were collected at baseline by interview and via medical records.”
Method
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“reported a clinically important increase of ≥8 points [25] on the FACT-B+4 score (score range: 0-160) between baseline to 12 months post-surgery.”
Background
Patterns of occurrence and implications of neratinib-associated diarrhea in patients with HER2-positive breast cancer: analyses from the randomized phase III ExteNET trial
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“6 points) reported in the US data [26].”
BackgroundInfluential
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“The FACT-B has a total of 37 questions, which are split among physical (PWB), social/family (SWB), emotional (EWB), functional well-being (FWB), and breast cancer-specific (BCS) subscales [30].”
Background
Effects of decisional conflict, decision regret and self‐stigma on quality of life for breast cancer survivors: A cross‐sectional, multisite study in China
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“…UBM/Lymphoedema questionnaire ( n = 5), The Breast Cancer and Lymphedema Symptom Experience Index (BCLE-SEI) [45] ( n = 1), Functional Assessment of Cancer Therapy, Breast-Arm Symptom Subscale [46] ( n = 1), or the “breast swelling” item on the EORTC QLQ-BR23 questionnaire [47] ( n = 1).”
Background
Psychoneuroimmunology-Based Stress Management during Adjuvant Chemotherapy for Early Breast Cancer
Robins, J., McCain, N., Elswick, R. K., Walter, J. M., Gray, D. P., & Tuck, I. (2013) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2013/372908 · Cited by 35
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Stinchcombe, T. E., & Socinski, M. A. (2010) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e318200f9c5 · Cited by 34
Impact of preservation of the intercostobrachial nerve during axillary dissection on sensory change and health-related quality of life 2 years after breast cancer surgery
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Menopausal symptoms in relationship to breast cancer-specific quality of life after adjuvant cytotoxic treatment in young breast cancer survivors
Yeo, W., Pang, E., Liem, G. S., Suen, J. J. S., Ng, R. Y. W., Yip, C. C. H., Li, L. V., Yip, C. H. W., & Mo, F. K. F. (2020) · Health and Quality of Life Outcomes · doi:10.1186/s12955-020-1283-x · Cited by 34
Self-citation
Pilot Study of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer
Greer, J. A., MacDonald, J. J., Vaughn, J., Viscosi, E., Traeger, L. N., McDonnell, T. M., Pirl, W. F., & Temel, J. S. (2015) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2015.06.010 · Cited by 34
Measuring Quality of Life in Cancer Survivors
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Self-citation
Randomized controlled trial of Nuevo Amanecer: A peer-delivered stress management intervention for Spanish-speaking Latinas with breast cancer
Nápoles, A. M., Santoyo‐Olsson, J., Ortíz, C., Gregorich, S. E., Lee, H. E., Durón, Y., Graves, K. D., Luce, J. A., McGuire, P., Díaz-Méndez, M., et al. (2014) · Clinical Trials · doi:10.1177/1740774514521906 · Cited by 34
“Primary outcomes are the total score from the Functional Assessment of Cancer Therapy– Breast Quality of Life Instrument and its five subscale scores [42].”
Background
Giving patients a choice improves quality of life: a multi-centre, investigator-blind, randomised, crossover study comparing letrozole with anastrozole
Thomas, R., Godward, S., Makris, A., Bloomfield, D. J., Moody, A. M., & Williams, M. (2004) · Clinical Oncology · doi:10.1016/j.clon.2004.06.023 · Cited by 35
Measuring Quality of Life of Long-Term Breast Cancer Survivors: The Long Term Quality of Life–Breast Cancer (LTQOL-BC) Scale
Gordon, N. H., & Siminoff, L. A. (2010) · Journal of Psychosocial Oncology · doi:10.1080/07347332.2010.516806 · Cited by 34
“Several cancerspecific measures exist that are designed to measure QOL in patients during or shortly after treatment, such as the Cancer Rehabilitation Evaluation System (CARES; Ganz, Schag, & Cheng, 1990) and the Functional Assessment for Cancer Therapy-Breast (FACT-B; Brady et al., 1997).”
Background
Cancer Patient and Survivor Research From the Cancer Information Service Research Consortium: A Preview of Three Large Randomized Trials and Initial Lessons Learned
Marcus, A. C., Diefenbach, M. A., Stanton, A. L., Miller, S. M., Fleisher, L. G., Raich, P. C., Morra, M. E., Perocchia, R. S., Tran, Z. V., & Bright, M. A. (2013) · Journal of Health Communication · doi:10.1080/10810730.2012.743629 · Cited by 33
“, 1993; Schag, Heinrich, Aadland, & Ganz, 1990) and various project-specific assessments of functional health status, fatigue, vitality, and quality of life (Brady et al., 1997; Broadbent, Petrie, Main, & Weinman, 2006; Esper et al., 1997; Ganz, Day, Ware, Redmond, & Fisher, 1995; Ware, Kosinski, & Keller, 1996; Yelle…”
Fatigue-Based Subgroups of Breast Cancer Survivors With Insomnia
Dirksen, S. R., Belyea, M. J., & Epstein, D. R. (2009) · Cancer Nursing · doi:10.1097/ncc.0b013e3181a5d05e · Cited by 33
“90 with convergent, divergent, and known groups validity.(30) At baseline, Cronbach ! for the FACT-B was .”
Background
A self‐directed home yoga programme for women with breast cancer during chemotherapy: A feasibility study
Komatsu, H., Yagasaki, K., Yamauchi, H., Yamauchi, T., & Takebayashi, T. (2015) · International Journal of Nursing Practice · doi:10.1111/ijn.12419 · Cited by 33
Translation and Adaptation of the Genetic Counselling Outcome Scale (GCOS‐24) for Use in Denmark
Diness, B. R., Overbeck, G., Hjortshøj, T. D., Hammer, T. B., Timshel, S., Sørensen, E., & McAllister, M. (2017) · Journal of Genetic Counseling · doi:10.1007/s10897-017-0086-7 · Cited by 33
“Empowerment”
Sharing in care: engaging care partners in the care and communication of breast cancer patients
Wolff, J. L., Aufill, J., Echavarria, D. M., Heughan, J.-A., Lee, K. T., Connolly, R. M., Fetting, J. H., Jelovac, D., Papathakis, K., Riley, C. D., et al. (2019) · Breast Cancer Research and Treatment · doi:10.1007/s10549-019-05306-9 · Cited by 33
Effects of the ACTIVity And TEchnology (ACTIVATE) intervention on health‐related quality of life and fatigue outcomes in breast cancer survivors
Vallance, J. K., Nguyen, N. H., Moore, M. M., Reeves, M. M., Rosenberg, D. E., Boyle, T., Milton, S., Friedenreich, C. M., English, D. R., & Lynch, B. M. (2019) · Psycho-Oncology · doi:10.1002/pon.5298 · Cited by 31
“The FACT-B and FACIT-Fatigue are widely used measurement tools that have established evidence of internal consistency, test-retest reliability, and convergent and discriminant validity.(14)”
Method
Lipid/Hyaluronic Acid–Coated Doxorubicin-Fe3O4 as a Dual-Targeting Nanoparticle for Enhanced Cancer Therapy
Liang, J., Yang, X., Liu, D., Cong, M., Song, Y., & Bai, S. (2020) · AAPS PharmSciTech · doi:10.1208/s12249-020-01764-3 · Cited by 33
Every Day Counts: a randomized pilot lifestyle intervention for women with metastatic breast cancer
Sheean, P., Matthews, L., Visotcky, A. M., Banerjee, A., Moosreiner, A., Kelley, K., Chitambar, C. R., Papanek, P. E., & Stolley, M. R. (2021) · Breast Cancer Research and Treatment · doi:10.1007/s10549-021-06163-1 · Cited by 33
“In doing so, we discovered our participants’ baseline scores for physical, social, emotional and functional well-being were higher compared to a larger, more heterogeneous sample of women with MBC [49], but below those for physical, social and functional well-being when compared to a normative sample compromised large…”
Result

Authors: Brady, M. J., Cella, D. F., Mo, F., Bonomi, A. E., Tulsky, D. S., Lloyd, S. R., Deasy, S., Cobleigh, M., & Shiomoto, G.
Affiliations: Rush University Medical Center (US)
Rush University (US)
ORCID: Cella, D F
Bonomi, A E
Tulsky, D S
Lloyd, S R
Cobleigh, M
Venue: Journal of Clinical Oncology
Publisher: American Society of Clinical Oncology (ASCO)
Published: 1997-03
Volume: 15
Issue: 3
Pages: 974-986
ISSN: 0732-183X (ISSN-L)
1527-7755
DOI: 10.1200/jco.1997.15.3.974
OpenAlex: W1857624176
Cited by: 1,752
References: 39
Citations by year: 2026: 47 · 2025: 76 · 2024: 77 · 2023: 71 · 2022: 97 · 2021: 88 · 2020: 78 · 2019: 87 · 2018: 83 · 2017: 85 · 2016: 83 · 2015: 73 · 2014: 83 · 2013: 70 · 2012: 86
FWCI: 5.28
Type: journal article
Language: en
Open access: closed
Locations: Journal of Clinical Oncology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (1r29ca051926-01a1)
National Cancer Institute (R29CA51926)
Topics: Health Sciences › Medicine › Oncology › Cancer survivorship and care
Health Sciences › Nursing › Research and Theory › Health Education and Validation
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Keywords: FACT-B, breast cancer, quality of life, FACT-G, instrument validation, sensitivity to change, test-retest reliability, internal consistency, known-groups validity, convergent validity, discriminant validity, physical well-being, functional well-being, emotional well-being, Functional Living Index-Cancer, self-report questionnaire
MeSH terms: Adult, Aged, Aged, 80 and over, Breast Neoplasms, Female, Humans, Middle Aged, Quality of Life, Self Concept, Sensitivity and Specificity, Severity of Illness Index, Translations, Reproducibility of Results

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Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument.

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