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Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument.
Abstract
PURPOSE: This is the first published report on the validation of the Functional Assessment of Cancer Therapy-Breast (FACT-B), a 44-item self-report instrument designed to measure multidimensional quality of life (QL) in patients with breast cancer. The FACT-B consists of the FACT-General (FACT-G) plus the Breast Cancer Subscale (BCS), which complements the general scale with items specific to QL in breast cancer. The FACT-B was developed with an emphasis on patients' values and brevity and is available in nine languages. METHODS AND RESULTS: Two validation samples were used for this report. The first (n = 47) was tested twice over a 2-month period to assess sensitivity to change. Significant sensitivity to change in performance status rating (PSR) was demonstrated for the FACT-B total score, the Physical Well-Being (PWB) subscale, the Functional Well-Being (FWB) subscale, and the BCS. Sensitivity to change in QL as measured by the Functional Living Index-Cancer (FLIC) was documented in the FACT-B total score, PWB, FWB, and Emotional Well-Being (EWB). Additional validity and reliability data were obtained from a larger sample (n = 295). The alpha coefficient (internal consistency) for the FACT-B total score was high (alpha = .90), with subscale alpha coefficients ranging from .63 to .86. Evidence supported test-retest reliability, as well as convergent, divergent, and known groups validity. CONCLUSION: The FACT-B is appropriate for use in oncology clinical trials, as well as in clinical practice. It demonstrates ease of administration, brevity, reliability, validity, and sensitivity to change.
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Self-citationTransitions of Male Partners of Women With Breast Cancer: Hope, Guilt, and Quality of Life
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“01) measure of quality of life in women with breast cancer (Brady et al., 1997).”
Hesketh, P. J., Chansky, K., Lau, D. H., Doroshow, J. H., Moinpour, C. M., Chapman, R., Goodwin, J. W., Gross, H. M., Crowley, J. J., & Gandara, D. R. (2006) · Journal of Thoracic Oncology · doi:10.1016/s1556-0864(15)30356-7 · Cited by 27
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“Medical experiences Quality of life FACT-B (32) B, FU1, FU2, HT Satisfaction with treatment decisions (chemotherapy) Satisfaction with Decision Scale (33,34) FU1, FU2, HT”
MethodQuality of Life and the Effect on Social Status among Slovenian Women after Breast Cancer Treatment
Gorišek, B., Krajnc, P., & Krajnc, I. (2009) · Journal of International Medical Research · doi:10.1177/147323000903700233 · Cited by 26
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Patient-Reported Outcomes and Long-Term Nonadherence to Aromatase Inhibitors
Hershman, D. L., Neugut, A. I., Moseley, A. B., Arnold, K. B., Gralow, J. R., Henry, N. L., Hillyer, G. C., Ramsey, S. D., & Unger, J. M. (2021) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djab022 · Cited by 26
“The Functional Assessment of Cancer Therapy—Endocrine Symptoms (FACT-ES) measures physical, social, family, emotional, and functional well-being; a subscale reflecting the total of these domains (the FACT-general [G]); and endocrine symptoms (17).”
BackgroundTripathy, D., Rugo, H. S., Kaufman, P. A., Swain, S. M., O’Shaughnessy, J., Jahanzeb, M., Mason, G., Beattie, M. S., Yoo, B., Lai, C., et al. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-307 · Cited by 26
“Data from the following PRO assessments (Table 2) are collected in self-completed questionnaires at 90-day intervals (approximately) during clinic visits: Overall Health Related Quality-of-Life Question [Genentech, data on file], Functional Assessment of Cancer Therapy-Breast [29], alopecia patient assessment for pati…”
MethodThomson, H. J., Winters, Z., Brandberg, Y., Didier, F., Blazeby, J. M., & Mills, J. (2012) · European Journal of Cancer · doi:10.1016/j.ejca.2012.09.021 · Cited by 26
Maïo, M. D., Leighl, N. B., Gallo, C., Feld, R. D., Ciardiello, F., Butts, C. A., Maione, P., Gebbia, V., Morgillo, F., Wierzbicki, R. F., et al. (2012) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e318275b327 · Cited by 26
Kirsh, K. L., McGrew, J. H., Dugan, M. J., & Passik, S. D. (2004) · Palliative & Supportive Care · doi:10.1017/s1478951504040040 · Cited by 26
“The measure has been shown to yield adequate to high internal consistency, exhibiting coefficient alphas ranging from 0.63 to 0.86 for the subscales and 0.90 to 0.95 for the total scale ~Cella et al., 1995; Brady et al., 1997!.”
BackgroundInfluentialHealth outcome and economic measurement in breast cancer surgery: challenges and opportunities
Cano, S., Klassen, A. F., Scott, A., Thoma, A., Feeny, D. H., & Pusic, A. L. (2010) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1586/erp.10.61 · Cited by 26
Niu, H., Niu, C., Wang, J., Zhang, Y., & He, P. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.8.3533 · Cited by 26
“…fatigue, and impact on the family, which are common to a wide range of cancer diagnoses, but also the breast cancer-specific factors such as an hot flashes, an altered sense of femininity, feelings of decreased attractiveness, and problems with treatmentrelated arm swelling (Brady et al., 1997).”
BackgroundKemp, E., Prior, K. N., Beatty, L., Lambert, S., Brown, C. S. B., & Koczwara, B. (2018) · European Journal of Cancer Care · doi:10.1111/ecc.12875 · Cited by 29
Welch, W. A., Ehlers, D. K., Gavin, K. L., Aguiñaga, S., Cottrell, A., Nielsen, A. M., Solk, P., McAuley, E., & Phillips, S. M. (2019) · Psycho-Oncology · doi:10.1002/pon.5091 · Cited by 26
“87).(20) Internal consistency for the FACT‐B was α = 0.”
BackgroundHan, J. Y., Kim, E., Lee, Y.-I., Shah, D. V., & Gustafson, D. H. (2019) · Journal of Health Communication · doi:10.1080/10810730.2019.1644401 · Cited by 26
“We also used the breast cancer-related concerns subscale of the Functional Assessment of Cancer Therapy-Breast (Brady et al., 1997) as another outcome measure.”
MethodSantoyo‐Olsson, J., Stewart, A. L., Samayoa, C., Palomino, H., Urias, A., Gonzalez, N., Torres‐Nguyen, A., Coleman, L., Escalera, C., Totten, V. Y., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0224068 · Cited by 26
“Primary outcomes were the Functional Assessment of Cancer Therapy—Breast (FACT-B) [ 39] subscales and total score.”
BackgroundInfluentialCross-Cultural Evaluation of Health Status Using Item Response Theory
Hahn, E. A., Holzner, B., Kemmler, G., Sperner‐Unterweger, B., Hudgens, S. A., & Cella, D. F. (2005) · Evaluation & the Health Professions · doi:10.1177/0163278705275343 · Cited by 26
“A study to describe the HRQOL of U.S. African American women with breast cancer reported that mean scores on the Functional Assessment of Cancer Therapy–Breast (FACT-B; Brady et al., 1997) were similar or slightly higher than those reported for the U.S. questionnaire validation sample, and the total score was able to…”
BackgroundMethodResultInfluentialSelf-citationTolaney, S. M., DeMichele, A. M., Takano, T., Rugo, H. S., Perou, C. M., Lynce, F. C., Parsons, H. A., Santa-Maria, C. A., Rocque, G. B., Yao, W., et al. (2024) · Future Oncology · doi:10.1080/14796694.2024.2357534 · Cited by 27
Ischemic compression and kinesiotherapy on chronic myofascial pain in breast cancer survivors
Rangon, F. B., Ferreira, V. T. K., Rezende, M. S., Apolinário, A., Ferro, A. P., & Guirro, E. C. D. O. (2017) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2017.04.005 · Cited by 25
Baik, S. H., Oswald, L. B., Buscemi, J., Buitrago, D., Iacobelli, F., Perez-Tamayo, A. M., Guitelman, J., Penedo, F. J., & Yanez, B. R. (2020) · JMIR Cancer · doi:10.2196/17538 · Cited by 26
“Established minimally important differences for the FACT-B subscales (ie, a minimum of 2 points) [49-51] were used to characterize changes in the HRQoL subdomains across time.”
MethodInfluentialHealth-Related Quality of Life Among Patients With HR+/HER2– Early Breast Cancer
Criscitiello, C., Spurden, D., Piercy, J., Rider, A., Williams, R., Mitra, D., Wild, R., Corsaro, M., Kurosky, S. K., & Law, E. H. (2021) · Clinical Therapeutics · doi:10.1016/j.clinthera.2021.04.020 · Cited by 25
Noguchi, N., Maruyama, I., & Yamada, A. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/704619 · Cited by 25
Zhou, Q., Shen, J., Liu, Y., Lin, G., Dong, H., & Li, K. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.14.5639 · Cited by 25
“The FACT-B is a 36- item self-report questionnaire designed to measure the multidimensional quality of life in patients with breast Asian Pacific Journal of Cancer Prevention, Vol 15, 2014 5641 cancer, including the FACT-General (FACT-G) (including physical well-being (PWB), social/family well-being (SWB), emotional w…”
BackgroundInfluentialNekhlyudov, L., Kroenke, C. H., Jung, I., Holmes, M. D., & Colditz, G. A. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.04.6219 · Cited by 25
Jeitler, M., Jaspers, J., von Scheidt, C., Koch, B., Michalsen, A., Steckhan, N., & Keßler, C. S. (2017) · Psycho-Oncology · doi:10.1002/pon.4433 · Cited by 26
“The study population was comparable overall to those in other cancer trials regarding sociodemographic characteristics.(21,22,26) The minimally important difference for the FACT‐G is defined as a value of 5 and for the FACT‐B, 7 points; in our study, the increase was greater than 5 respectively 7 points resulting in a…”
MethodResultMindfulness-based cognitive therapy for Japanese breast cancer patients—a feasibility study
Park, S., Sado, M., Fujisawa, D., Sato, Y., Takeuchi, M., Ninomiya, A., Takahashi, M., Yoshimura, K., Jinno, H., & Takeda, Y. (2017) · Japanese Journal of Clinical Oncology · doi:10.1093/jjco/hyx156 · Cited by 25
“Significant improvement in anxiety (Hospital Anxiety and Depression Scale (HADS) – anxiety subscale; effect size Cohen’s d = 0.88, P < 0.05), trauma-related psychological symptoms (Impact of Event Scale-revised; d = 0.64, P < 0.01) and quality of life (Functional Assessment of Cancer Therapy-Breast Cancer: FACT-B; d =…”
MethodInfluentialFeasibility Study of an Online Intervention to Support Male Spouses of Women With Breast Cancer
Duggleby, W., Ghosh, S., Montford, K. S., Nekolaichuk, C., Cumming, C. E., Thomas, R. L., Tonkin, K. S., & Swindle, J. (2017) · Oncology nursing forum · doi:10.1188/17.onf.765-775 · Cited by 25
“Functional Assessment of Cancer–Breast: QOL of the women with breast cancer was measured using the Functional Assessment of Cancer–Breast (FACT-B) questionnaire (Brady et al., 1997).”
MethodPanda, N., Solsky, I. B., Hawrusik, B., Liu, G., Reeder, H. T., Lipsitz, S. R., Desai, E. V., Lowery, K. W., Miller, K., Gadd, M. A., et al. (2020) · Annals of Surgical Oncology · doi:10.1245/s10434-020-09004-5 · Cited by 25
Temple‐Oberle, C. F., Cook, E. F., Bettger‐Hahn, M., Mychailyshyn, N., Naeem, H., & MacDermid, J. C. (2012) · Journal of Surgical Oncology · doi:10.1002/jso.23114 · Cited by 25
“We elected to use classical measurement theory (CMT) to develop the BRECON-31, consistent with the developers of the BIBCQ, FACT-B, and EORTC-QLQ-BR23.”
MethodInfluentialPatoo, M., Allahyari, A. A., Moradi, A., & Payandeh, M. (2015) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2015.16.9.3799 · Cited by 25
“They were asked to fill in the Persian versions of the FACT-B scale, Hospital Anxiety and Depression Scale, the European Organization for Research and Treatment of Cancer quality of life EORTC QLQ30.”
BackgroundInfluentialOh, Y. K., & Hwang, S. Y. (2018) · Journal of Korean Academy of Nursing · doi:10.4040/jkan.2018.48.1.50 · Cited by 24
Engagement with a Social Networking Intervention for Cancer-Related Distress
Owen, J. E., Bantum, E. O., Gorlick, A., & Stanton, A. L. (2014) · Annals of Behavioral Medicine · doi:10.1007/s12160-014-9643-6 · Cited by 24
Variations in COMT and NTRK2 Influence Symptom Burden in Women Undergoing Breast Cancer Treatment
Young, E. E., Kelly, D. L., Shim, I., Baumbauer, K. M., Starkweather, A. R., & Lyon, D. (2017) · Biological Research For Nursing · doi:10.1177/1099800417692877 · Cited by 23
“The functional assessment of cancer therapy for breast cancer (FACT-B; Brady et al., 1997) is a 44-item selfreport instrument designed to measure multidimensional QOL in patients with breast cancer.”
MethodProspective Multicentered Safety and Feasibility Pilot for Endobronchial Intratumoral Chemotherapy
Yarmus, L. B., Mallow, C. M., Akulian, J., Lin, C. T., Ettinger, D. S., Hales, R. K., Voong, K. R., Lee, H. C., Feller-Kopman, D. J., Semaan, R. W., et al. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.02.006 · Cited by 24
Kovačević, P., Miljković, S., Visnjic, A. M., Kozarski, J., & Jankovic, R. J. (2020) · Medicina · doi:10.3390/medicina56080402 · Cited by 24
“The FACT-B is a breast cancer-specific HRQoL instrument of the FACIT system [27].”
BackgroundMethodInfluentialA scoping review of measures used to assess body image in women with breast cancer
Brunet, J., & Price, J. (2021) · Psycho-Oncology · doi:10.1002/pon.5619 · Cited by 24
Çorum, M., Başoğlu, C., Korkmaz, M. D., Yildirim, M., & Öneş, K. (2021) · Lymphatic Research and Biology · doi:10.1089/lrb.2020.0099 · Cited by 24
Yusof, K. M., Avery‐Kiejda, K. A., Suhaimi, S. A., Zamri, N. A., Rusli, M. E. F., Mahmud, R., Saini, S. M., Ibraheem, S. A. W., Abdullah, M., & Rosli, R. (2021) · Diagnostics · doi:10.3390/diagnostics11081303 · Cited by 24
“A bilingual (Malay and English) and selfadministered questionnaire was provided to collect demographic, medical, and breast cancer information.”
MethodGrujic, D., Giurgi-Oncu, C., Oprean, C. M., Crăiniceanu, Z. P., Secoșan, I., Rivis, I. A., Papavă, I., Vernic, C., & Bredicean, C. A. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18179320 · Cited by 24
“For the purposes of this study, we chose to highlight two specific items included in the Additional concerns/Breast Cancer Subscale, namely B4 (“I feel sexually attractive”) and B9 (“I am able to feel like a woman”), as they directly relate to the concept of feminine aesthetics and sexuality, representing some of the…”
MethodLoubani, K., Schreuer, N., & Kizony, R. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11041022 · Cited by 24
“The FACT-B has good reliability, validity, and internal consistencies [41].”
BackgroundCoronado, P., Sánchez‐Borrego, R., Ruiz, M. Á., Baquedano, L., Sánchez, S., Argudo, C., Fernández-Abellán, M., Rodríguez, S. P. G., Iglesias, E., Calleja, J., et al. (2015) · Maturitas · doi:10.1016/j.maturitas.2015.10.013 · Cited by 24
Corey‐Lisle, P. K., Peck, R., Mukhopadhyay, P., Orsini, L. S., Safikhani, S., Bell, J. A., Hortobágyi, G. N., Roche, H. H., Conte, P., & Revicki, D. A. (2011) · Cancer · doi:10.1002/cncr.26213 · Cited by 24
“QOL endpoints have become as important as other traditional endpoints such as progression-free survival (PFS) or tumor response in oncology clinical trials.(8,10) Given the benefits in delayed disease progression and the risks associated with increased toxicity, it is important to compare subjective treatment risks an…”
BackgroundMiller, C. L., Specht, M. C., Skolny, M. N., Jammallo, L. S., Horick, N., O’Toole, J. A., Coopey, S. B., Hughes, K. S., Gadd, M. A., Smith, B. L., et al. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-2231-1 · Cited by 24
“Lymphedema symptom data was collected via patient self-report using the LEFT-BC Questionnaire which contained sections from multiple validated surveys utilized for lymphedema assessment [27, 35-37].”
MethodAnastrozole and letrozole: an investigation and comparison of quality of life and tolerability
Dixon, J. M., Renshaw, L., Langridge, C., Young, O., McHugh, M., Williams, L. J., Murray, J., Macaskill, E. J., McCaig, F., Dixon, O. M., et al. (2010) · Breast Cancer Research and Treatment · doi:10.1007/s10549-010-1091-9 · Cited by 24
“The ES assesses endocrine side effects and comprises 18 items designed for use with the FACT-B [14, 15].”
MethodSentinel node biopsy and quality of life measures in a Chinese population
Chen, J.-J., Huang, X., Liu, Z.-B., Chen, T.-W., Cheng, J., Yang, W. T., Xu, W.-P., Shao, Z., Shen, Z., & Wu, J. (2009) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2009.01.009 · Cited by 24
“The FACT-B scale was used to assess QoL of patients with breast cancer, which contains 36-items, cancer sitespecific instrument including questions regarding breast, emotional, functional, physical, and social well-being.(20) Comparing the postoperative QoL assessed with help of FACT-B in simplified Chinese version be…”
MethodJiang, Y., Sereika, S. M., Bender, C. M., Brufsky, A., & Rosenzweig, M. Q. (2016) · Oncology nursing forum · doi:10.1188/16.onf.180-189 · Cited by 24
Does a peer‐led exercise intervention affect sedentary behavior among breast cancer survivors?
Pinto, B. M., DUNSIGER, S. I., & Stein, K. (2016) · Psycho-Oncology · doi:10.1002/pon.4255 · Cited by 24
“(d) Functional Assessment of Cancer Therapy Scale for Breast Cancer is a 55‐item scale that assesses QOL and is reliable and valid.(27) The range of scores is 0 to 144, with higher scores indicating a better QOL.”
BackgroundNiklasson, A., Paty, J. A., & Rydén, A. (2017) · Patient · doi:10.1007/s40271-017-0242-z · Cited by 24
Wan, C., Tang, X., Tu, X. M., Feng, C., Messing, S. P., Meng, Q., & Zhang, X. (2007) · Breast Cancer Research and Treatment · doi:10.1007/s10549-006-9443-1 · Cited by 24
Assessment of quality of life and symptom improvement in lung cancer clinical trials
Sarna, L. P., & Riedinger, M. S. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.04.007 · Cited by 24
Dieli-Conwright, C. M., Fox, F., Tripathy, D., Sami, N., Fleet, J. V., Buchanan, T. A., SPICER, D. V., Lee, K., Mortimer, J. E., Bernstein, L., et al. (2020) · Journal of Cancer Survivorship · doi:10.1007/s11764-020-00918-3 · Cited by 21
Sheppard, V. B., Sutton, A. L., Hurtado‐de‐Mendoza, A., He, J., Dahman, B. A., Edmonds, M. C., Hackney, M. H., & Tadesse, M. G. (2021) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-20-0604 · Cited by 25
Chatterjee, S., Chakrabarty, S., Santosham, R. J. M., Saha, A., Mallick, I., Arunsingh, M. A., Bhattacharya, T., Achari, R. B., Agrawal, S. K., Ahmed, R., et al. (2023) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2023.02.008 · Cited by 23
Assessment of Patient-Reported Outcomes in Patients with Melanoma
Cormier, J. N., & Askew, R. L. (2010) · Surgical Oncology Clinics of North America · doi:10.1016/j.soc.2010.09.002 · Cited by 23
Quality‐of‐life outcomes in patients with advanced melanoma: A review of the literature
Malkhasyan, K. A., Zakharia, Y., & Milhem, M. M. (2017) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12647 · Cited by 24
Robertson, J. F. R., Cheung, K., Noguchi, S., Shao, Z., Degboe, A., Lichfield, J., Thirlwell, J., Fazal, M., & Ellis, M. J. (2018) · European Journal of Cancer · doi:10.1016/j.ejca.2018.02.026 · Cited by 23
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Health-Related Quality of Life in Patients with Melanoma: Overview of Instruments and Outcomes
Cormier, J. N., Cromwell, K. D., & Ross, M. I. (2011) · Dermatologic Clinics · doi:10.1016/j.det.2011.11.011 · Cited by 23
Natale, R. B. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.04.010 · Cited by 23
Quality of life considerations in patients with advanced lung cancer
Cella, D. F. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.10.004 · Cited by 23
Self-citationFear of Cancer Recurrence and Sleep in Couples Coping With Early-Stage Breast Cancer
Perndorfer, C., Soriano, E. C., Siegel, S. D., Spencer, R. M. C., Otto, A. K., & Laurenceau, J.-P. (2022) · Annals of Behavioral Medicine · doi:10.1093/abm/kaac018 · Cited by 21
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Chen, Z., Wang, Q., Sun, Y., Cai, H., & Lü, X. (2024) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2024.104651 · Cited by 24
Weng, J. K., Lei, X. J., Schlembach, P. J., Bloom, E. S., Shaitelman, S. F., Arzu, I., Chronowski, G. M., Dvořák, T., Grade, E., Hoffman, K. E., et al. (2021) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2021.05.004 · Cited by 22
Tollens, F., Baltzer, P., Dietzel, M., Schnitzer, M. L., Schwarze, V., Kunz, W. G., Rink, J. S., Rübenthaler, J., Froelich, M. F., Schönberg, S. O., et al. (2022) · European Radiology · doi:10.1007/s00330-022-08777-5 · Cited by 22
Modi, N. D., Danell, N. O., Perry, R. N. A., Abuhelwa, A. Y., Rathod, A., Badaoui, S., McKinnon, R. A., Haseloff, M., Shahnam, A., Swain, S. M., et al. (2022) · ESMO Open · doi:10.1016/j.esmoop.2022.100475 · Cited by 23
“0 questionnaire in all three studies.(30) FACT-B is a self-reported 37-item questionnaire that measures multidimensional health-related quality of life in patients with BC.”
BackgroundMavropalias, G., Cormie, P., Peddle‐McIntyre, C. J., Galvao, D. A., Taaffe, D. R., Schofield, C., Ray, S., Zissiadis, Y., & Newton, R. U. (2022) · Breast Cancer · doi:10.1007/s12282-022-01408-3 · Cited by 25
“HRQoL was assessed using the Functional Assessment of Cancer Therapy for patients with BCa (FACT-B + 4) [20], to assess a variety of domains including physical wellbeing,”
MethodComparison of early quality of life outcomes in autologous and allogeneic transplant patients
Garcia, C. M., Mumby, P. B., Thilges, S., & Stiff, P. J. (2012) · Bone Marrow Transplantation · doi:10.1038/bmt.2012.77 · Cited by 22
Floyd, A. R., Dedert, E. A., Ghate, S. R., Salmon, P. M., Weissbecker, I., Studts, J. L., Stetson, B. A., & Sephton, S. E. (2010) · Journal of Health Psychology · doi:10.1177/1359105310371856 · Cited by 22
Trial of Essiac to Ascertain Its Effect in Women with Breast Cancer (TEA-BC)
Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., & Boon, H. S. (2006) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2006.12.971 · Cited by 22
“Each woman received a packet that contained 5 surveys including (1) the FACT-B, 21 which is a 44-item self-administered, 5-point Likert scale for evaluating functional impairment and the perceived effect of that impairment on quality of life; (2) POMS, 22 which is a measure of patient distress; (3) Yale Social Support…”
InfluentialWan, C., Yang, Z., Tang, X., Zou, T., Chen, D., Zhang, D., & Meng, Q. (2008) · Supportive Care in Cancer · doi:10.1007/s00520-008-0478-1 · Cited by 22
“The QLQs from EORTC and the FACTs from Center on Outcomes, Research and Education (CORE) have been developed based on this modular principle [1, 3, 4, 11].”
MethodMercieca‐Bebber, R., King, M. T., Boxer, M. M., Spillane, A. J., Winters, Z., Butow, P. N., McPherson, J., & Rutherford, C. (2017) · Breast Cancer · doi:10.1007/s12282-017-0765-0 · Cited by 22
Fisher, H. M., Jacobs, J. M., Taub, C. J., Lechner, S. C., Lewis, J. E., Carver, C. S., Blomberg, B. B., & Antoni, M. H. (2017) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2017.05.007 · Cited by 24
“Functional QoL The 7-item Functional Well-Being subscale of The Functional Assessment of Cancer Therapy for Breast Cancer (FACT-B) [31,32] was used to assess functional QoL.”
Brunelle, C. L., Roberts, S. A., Shui, A. M., Gillespie, T. C., Daniell, K. M., Naoum, G. E., & Taghian, A. G. (2020) · Journal of Surgical Oncology · doi:10.1002/jso.25944 · Cited by 22
Mapping the cancer-specific FACT-B onto the generic SF-6Dv2
Nahvijou, A., Safari, H., Yousefi, M., Rajabi, M., Arab‐Zozani, M., & Ameri, H. (2020) · Breast Cancer · doi:10.1007/s12282-020-01141-9 · Cited by 22
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Psychospiritual well-being and symptom distress in women with breast cancer.
Manning-Walsh, J. (2005) · PubMed · doi:10.1188/04.onf.e56-e65 · Cited by 23
Gefitinib (‘Iressa’): a new therapy for advanced non-small-cell lung cancer
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Md Yusof, K., Mahmud, R., Abdullah, M., Avery-Kiejda, K. A., & Rosli, R. (2021) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2021.22.4.1055 · Cited by 20
“Unlike the other general domains which have homogenous construct, BCS is uniquely designed to include important items identified in breast cancer, but not covered in the main domains, FACT-G (Brady et al., 1997).”
BackgroundMethodInfluentialMortimer, J. E., & Behrendt, C. E. (2013) · Journal of Palliative Medicine · doi:10.1089/jpm.2012.0585 · Cited by 21
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Charalampopoulou, M., Bacopoulou, F., Syrigos, K. N., Fillopoulos, E., Chrousos, G. P., & Darviri, C. (2019) · The Breast · doi:10.1016/j.breast.2019.12.012 · Cited by 24
Skandarajah, A. R., Lisy, K., Ward, A. C., Bishop, J., Lacey, K., Mann, G. B., & Jefford, M. (2020) · Quality of Life Research · doi:10.1007/s11136-020-02652-w · Cited by 21
Benson, J. A., Bhandari, P., Lui, N. S., Berry, M. F., Liou, D. Z., Shrager, J. B., Ayers, K., & Backhus, L. M. (2021) · Seminars in Thoracic and Cardiovascular Surgery · doi:10.1053/j.semtcvs.2021.03.003 · Cited by 21
Samami, E., Shahhosseini, Z., Hamzehgardeshi, Z., & Elyasi, F. (2022) · PubMed Central · doi:10.30476/ijms.2020.86657.1660 · Cited by 21
Loubani, K., Kizony, R., Milman, U., & Schreuer, N. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18115966 · Cited by 21
“The Functional Assessment of Cancer Therapy-Breast (FACT-B) assesses health-related QOL after BC diagnosis [48].”
BackgroundJoly, F., Pasquier, D., Lévy, C., Mousseau, M., D’Almeida, M., Noal, S., Tinier, F. L., Geffrelot, J., Ciais, C., Szymczak, V., et al. (2022) · Psycho-Oncology · doi:10.1002/pon.5940 · Cited by 21
Yamamoto, Y., Iwata, H., Taira, N., Masuda, N., Takahashi, M., Yoshinami, T., Ueno, T., Toyama, T., Yamanaka, T., Takano, T., et al. (2022) · Cancer Science · doi:10.1111/cas.15474 · Cited by 20
Wang, T.-C., Chen, P.-L., Liao, W.-C., & Tsai, I. (2023) · Cancers · doi:10.3390/cancers15133380 · Cited by 21
“If the study utilized a breast-cancer-specific quality-of-life scale, such as the Functional Assessment of Cancer Therapy-Breast [30,31] or the International Breast Cancer Study Group Quality of Life [32], data extraction was prioritized from these scales.”
MethodFocusing and Expressive Arts Therapy as a Complementary Treatment for Women with Breast Cancer
Klagsbrun, J., Rappaport, L., Speiser, V. M., Post, P., Byers, J. G., Stepakoff, S., & Karman, S. (2005) · Journal of Creativity in Mental Health · doi:10.1300/j456v01n01_08 · Cited by 21
“The Functional Assessment of Cancer Therapy for breast cancer, or FACT-B Scale (Brady et al., 1997), is a self-administered reporting instrument that measures the quality of life for a patient with breast cancer.”
BackgroundMiura, K., Ando, S., & Imai, T. (2014) · Breast Cancer · doi:10.1007/s12282-014-0578-3 · Cited by 21
“During the same period, Japanese medical care has focused only on monitoring patients for cancer recurrence after their initial treatment.”
BackgroundInfluentialLieberman, M. A., & Winzelberg, A. J. (2009) · Computers in Human Behavior · doi:10.1016/j.chb.2008.11.003 · Cited by 21
“Internal reliability (r = .88) (Brady et al., 1997).”
Sheppard, V. B., Hurtado‐de‐Mendoza, A., Zheng, Y., Wang, Y., Graves, K. D., Lobo, T., Xu, H., Jennings, Y., Tolsma, D., Trout, M., et al. (2017) · Journal of Cancer Survivorship · doi:10.1007/s11764-017-0646-8 · Cited by 21
Metadata
- Authors
- Brady, M. J., Cella, D. F., Mo, F., Bonomi, A. E., Tulsky, D. S., Lloyd, S. R., Deasy, S., Cobleigh, M., & Shiomoto, G.
- Affiliations
- Rush University Medical Center (US)
- Rush University (US)
- Venue
- Journal of Clinical Oncology
- Published
- 1997-03
- Volume
- 15
- Issue
- 3
- Pages
- 974-986
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W1857624176
- Cited by
- 1,752
- References
- 39
- Citations by year
- 2026: 47 · 2025: 76 · 2024: 77 · 2023: 71 · 2022: 97 · 2021: 88 · 2020: 78 · 2019: 87 · 2018: 83 · 2017: 85 · 2016: 83 · 2015: 73 · 2014: 83 · 2013: 70 · 2012: 86
- FWCI
- 5.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Oncology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1r29ca051926-01a1)
- National Cancer Institute (R29CA51926)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Nursing › Research and Theory › Health Education and Validation
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- FACT-B, breast cancer, quality of life, FACT-G, instrument validation, sensitivity to change, test-retest reliability, internal consistency, known-groups validity, convergent validity, discriminant validity, physical well-being, functional well-being, emotional well-being, Functional Living Index-Cancer, self-report questionnaire
- MeSH terms
- Adult, Aged, Aged, 80 and over, Breast Neoplasms, Female, Humans, Middle Aged, Quality of Life, Self Concept, Sensitivity and Specificity, Severity of Illness Index, Translations, Reproducibility of Results
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