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Randomized Study on the Efficacy of Cognitive-Behavioral Therapy for Insomnia Secondary to Breast Cancer, Part I: Sleep and Psychological Effects
Abstract
Purpose: Chronic insomnia is highly prevalent in cancer patients. Cognitive-behavioral therapy (CBT) is considered the treatment of choice for chronic primary insomnia. However, no randomized controlled study has been conducted on its efficacy for insomnia secondary to cancer. Using a randomized controlled design, this study conducted among breast cancer survivors evaluated the effect of CBT on sleep, assessed both subjectively and objectively, and on hypnotic medication use, psychological distress, and quality of life. Patients and Methods: Fifty-seven women with insomnia caused or aggravated by breast cancer were randomly assigned to CBT (n = 27) or a waiting-list control condition (n = 30). The treatment consisted of eight weekly sessions administered in a group and combined the use of stimulus control, sleep restriction, cognitive therapy, sleep hygiene, and fatigue management. Follow-up evaluations were carried out 3, 6, and 12 months after the treatment. Results: Participants who received the insomnia treatment had significantly better subjective sleep indices (daily sleep diary, Insomnia Severity Index), a lower frequency of medicated nights, lower levels of depression and anxiety, and greater global quality of life at post-treatment compared with participants of the control group after their waiting period. Results were more equivocal on polysomnographic indices. Therapeutic effects were well maintained up to 12 months after the intervention and generally were clinically significant. Conclusion: This study supports the efficacy of CBT for insomnia secondary to breast cancer.
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Citations
Cites
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., Filiberti, A., Flechtner, H., Fleishman, S. B., Haes, J. C. J. M. D., et al. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.5.365 · Cited by 16,005
Validation of the Insomnia Severity Index as an outcome measure for insomnia research
Bastien, C. (2001) · Sleep Medicine · doi:10.1016/s1389-9457(00)00065-4 · Cited by 8,067
Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy
(1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.8.1172 · Cited by 1,098
Self-citationBehavioral and Pharmacological Therapies for Late-Life Insomnia: A Randomized Controlled Trial
Morin, C. M., Colecchi, C., Stone, J., Sood, R., & Brink, D. (1999) · JAMA · doi:10.1001/jama.281.11.991 · Cited by 1,095
Self-citationPrevalence, burden, and treatment of insomnia in primary care
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.10.1417 · Cited by 694
Savard, M.-H., Savard, J., Simard, S., & Ivers, H. (2005) · Psycho-Oncology · doi:10.1002/pon.860 · Cited by 449
Self-citationPrevalence, Clinical Characteristics, and Risk Factors for Insomnia in the Context of Breast Cancer
Savard, J., Simard, S., Blanchet, J., Ivers, H., & Morin, C. M. (2001) · SLEEP · doi:10.1093/sleep/24.5.583 · Cited by 414
The analysis of repeated measures designs: A review
Keselman, H. J., Algina, J., & Kowalchuk, R. K. (2001) · British Journal of Mathematical and Statistical Psychology · doi:10.1348/000711001159357 · Cited by 306
Psychological treatment of secondary insomnia
Lichstein, K. L., Wilson, N. M., & Johnson, C. T. (2000) · Psychology and Aging · doi:10.1037/0882-7974.15.2.232 · Cited by 184
Cited by
Psychological and behavioral treatment of insomnia: update of the recent evidence (1998-2004)
Morin, C. M., Bootzin, R. R., Buysse, D. J., Edinger, J. D., Espie, C. A., & Lichstein, K. L. (2006) · Sleep · doi:10.1093/sleep/29.11.1398 · Cited by 1,345
Self-citationScott, A. J., Webb, T. L., Martyn-St James, M., Rowse, G., & Weich, S. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101556 · Cited by 1,094
Morin, C. M., & Benca, R. (2012) · The Lancet · doi:10.1016/s0140-6736(11)60750-2 · Cited by 976
Self-citationFaller, H., Schuler, M., Richard, M., Heckl, U., Weis, J., & Küffner, R. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2011.40.8922 · Cited by 912
Morin, C. M., Drake, C. L., Harvey, A. G., Krystal, A. D., Manber, R., Riemann, D., & Spiegelhalder, K. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.26 · Cited by 746
Self-citationCognitive and behavioral therapies in the treatment of insomnia: A meta-analysis
van Straten, A., van der Zweerde, T., Kleiboer, A., Cuijpers, P., Morin, C. M., & Lancee, J. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.02.001 · Cited by 676
Self-citationMajor depression after breast cancer: a review of epidemiology and treatment
Fann, J. R., Thomas-Rich, A. M., Katon, W. J., Cowley, D., Pepping, M., McGregor, B. A., & Gralow, J. (2008) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2007.10.008 · Cited by 586
Wu, J. Q., Appleman, E. R., Salazar, R. D., & Ong, J. C. (2015) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2015.3006 · Cited by 527
Lengacher, C. A., Johnson‐Mallard, V., Post‐White, J., Moscoso, M. S., Jacobsen, P. B., Klein, T. W., Widen, R. H., Fitzgerald, S. G., Shelton, M. M., Barta, M., et al. (2009) · Psycho-Oncology · doi:10.1002/pon.1529 · Cited by 518
Insomnia and health-related quality of life
Kyle, S. D., Morgan, K., & Espie, C. A. (2010) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2009.07.004 · Cited by 520
Duijts, S. F. A., Faber, M. M., Oldenburg, H. S. A., van Beurden, M., & Aaronson, N. K. (2011) · Psycho-Oncology · doi:10.1002/pon.1728 · Cited by 452
Savard, M.-H., Savard, J., Simard, S., & Ivers, H. (2005) · Psycho-Oncology · doi:10.1002/pon.860 · Cited by 449
Self-citationEspie, C. A. (2009) · SLEEP · doi:10.1093/sleep/32.12.1549 · Cited by 422
Johnson, J. A., Rash, J. A., Campbell, T. S., Savard, J., Gehrman, P. R., Perlis, M., Carlson, L. E., & Garland, S. N. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.07.001 · Cited by 371
Self-citationEspie, C. A., Fleming, L., Cassidy, J., Samuel, L., Taylor, L. M., White, C. A., Douglas, N. J., Engleman, H. M., Kelly, H.-L., & Paul, J. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.13.9006 · Cited by 383
Garland, S. N., Carlson, L. E., Stephens, A. J., Antle, M. C., Samuels, C., & Campbell, T. S. (2014) · Journal of Clinical Oncology · doi:10.1200/jco.2012.47.7265 · Cited by 329
Cognitive Behavioral Therapy in Persons with Comorbid Insomnia: A Meta-Analysis
Geiger-Brown, J. M., Rogers, V. E., Liu, W., Ludeman, E. M., Downton, K. D., & Diaz-Abad, M. (2015) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2014.11.007 · Cited by 331
Edinger, J. D., Arnedt, J. T., Bertisch, S. M., Carney, C. E., Harrington, J. J., Lichstein, K. L., Sateia, M. J., Troxel, W. M., Zhou, E. S., Kazmi, U., et al. (2021) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.8988 · Cited by 309
Ritterband, L. M., Bailey, E. T., Thorndike, F. P., Lord, H. R., Farrell‐Carnahan, L., & Baum, L. D. (2012) · Psycho-Oncology · doi:10.1002/pon.1969 · Cited by 296
Campbell, T., Garland, S., Johnson, J., Savard, J., Gehrman, P., Perlis, M., & Carlson, L. (2014) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s47790 · Cited by 250
Self-citationMind-Body Treatments for the Pain-Fatigue-Sleep Disturbance Symptom Cluster in Persons with Cancer
Kwekkeboom, K. L., Cherwin, C. H., Lee, J. W., & Wanta, B. (2010) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2009.05.022 · Cited by 228
“Savard et al.(63) and Epstein and Dirksen reported greater improvement in sleep, but no change in fatigue when four to eight weeks of CBT was compared to treatment as usual or sleep education.”
Gee, B., Orchard, F., Clarke, E., Joy, A., Clarke, T., & Reynolds, S. (2019) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2018.09.004 · Cited by 212
Meta-analytic review of the impact of cognitive-behavior therapy for insomnia on concomitant anxiety
Belleville, G., Cousineau, H., Levrier, K., & St-Pierre-Delorme, M.-È. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2011.02.004 · Cited by 207
Prevalence, Natural Course, and Risk Factors of Insomnia Comorbid With Cancer Over a 2-Month Period
Savard, J., Villa, J., Ivers, H., Simard, S., & Morin, C. M. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.21.6333 · Cited by 197
Self-citationEfficacy of an insomnia intervention on fatigue, mood and quality of life in breast cancer survivors
Dirksen, S. R., & Epstein, D. R. (2008) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2007.04560.x · Cited by 185
Tang, N. K. Y., Lereya, S. T., Boulton, H., Miller, M. A., Wolke, D., & Cappuccio, F. P. (2015) · Sleep · doi:10.5665/sleep.5158 · Cited by 176
Ballesio, A., Aquino, M. R. J. V., Feige, B., Johann, A. F., Kyle, S. D., Spiegelhalder, K., Lombardo, C., Rücker, G., Riemann, D., & Baglioni, C. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.01.006 · Cited by 172
Lengacher, C. A., Reich, R. R., Post-White, J., Moscoso, M., Shelton, M. M., Barta, M., Le, N., & Budhrani, P. (2012) · Journal of Behavioral Medicine · doi:10.1007/s10865-011-9346-4 · Cited by 170
Schneider, S., Moyer, A., Knapp-Oliver, S., Sohl, S., Cannella, D., & Targhetta, V. (2010) · Journal of Behavioral Medicine · doi:10.1007/s10865-009-9227-2 · Cited by 169
Behavioral therapy intervention trial to improve sleep quality and cancer-related fatigue
Berger, A. M., Kuhn, B. R., Farr, L. A., Lynch, J. C., Agrawal, S., Chamberlain, J., & Von Essen, S. G. (2009) · Psycho-Oncology · doi:10.1002/pon.1438 · Cited by 161
Efficacy of cognitive behavioral therapy for insomnia in breast cancer: A meta-analysis
Ma, Y., Hall, D. L., Ngo, L. H., Liu, Q., Bain, P. A., & Yeh, G. Y. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2020.101376 · Cited by 151
Randomized trial of a cognitive-behavioral intervention for insomnia in breast cancer survivors
Epstein, D. R., & Dirksen, S. R. (2007) · Oncology nursing forum · doi:10.1188/07.onf.e51-e59 · Cited by 152
Schwartz, D. R., & Carney, C. E. (2012) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.06.006 · Cited by 137
Savard, J., Ivers, H., Savard, M.-H., & Morin, C. M. (2014) · Sleep · doi:10.5665/sleep.3918 · Cited by 136
Self-citationAntoni, M. H., Moreno, P. I., & Penedo, F. J. (2023) · Annual Review of Psychology · doi:10.1146/annurev-psych-030122-124119 · Cited by 132
Clevenger, L., Schrepf, A., DeGeest, K., Bender, D., Goodheart, M., Ahmed, A., Dahmoush, L., Penedo, F., Lucci, J., Thaker, P. H., et al. (2013) · Cancer · doi:10.1002/cncr.28188 · Cited by 127
“For example, behavioral interventions such as cognitive behavioral therapy and mindfulness-based stress reduction have known effectiveness for insomnia(46,47) and have shown positive benefits in oncology patients.(48,49)”
Sleep problems in breast cancer survivors 1–10 years posttreatment
Lowery-Allison, A. E., Passik, S. D., Cribbet, M. R., Reinsel, R. A., O'Sullivan, B., Norton, L., Kirsh, K. L., & Kavey, N. B. (2018) · Palliative and Supportive Care · doi:10.1017/s1478951517000311 · Cited by 125
Cognitive behavioral treatment of insomnia
Williams, J., Roth, A., Vatthauer, K., & McCrae, C. S. (2013) · Chest · doi:10.1378/chest.12-0731 · Cited by 123
Matthews, H., Grunfeld, E. A., & Turner, A. (2017) · Psycho-Oncology · doi:10.1002/pon.4199 · Cited by 117
Home-based multidimensional survivorship programmes for breast cancer survivors
Cheng, K. K. F., Lim, Y. T. E., Koh, Z. M., & Tam, W. W. S. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011152.pub2 · Cited by 114
Chen, H.-Y., Chiang, C.-K., Wang, H.-H., Hung, K.-Y., Lee, Y.-J., Peng, Y.-S., Wu, K.-D., & Tsai, T.-J. (2008) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2008.03.012 · Cited by 111
Exercise interventions to improve sleep in cancer patients: a systematic review and meta-analysis
Mercier, J., Savard, J., & Bernard, P. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.11.001 · Cited by 103
Self-citationMatthews, E. E., Berger, A. M., Schmiege, S. J., Cook, P. F., McCarthy, M. S., Moore, C. M., & Aloia, M. S. (2014) · Oncology Nursing Forum · doi:10.1188/14.onf.41-03ap · Cited by 103
Insomnia in adult patients with cancer: ESMO Clinical Practice Guideline
Grassi, L., Zachariae, R., Caruso, R., Palagini, L., Campos-Ródenas, R., Riba, M. B., Lloyd-Williams, M., Kissane, D., Rodin, G., McFarland, D., et al. (2023) · ESMO Open · doi:10.1016/j.esmoop.2023.102047 · Cited by 96
Squires, L. R., Rash, J. A., Fawcett, J., & Garland, S. N. (2022) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2022.101615 · Cited by 85
Sleeping for Two: An Open-Pilot Study of Cognitive Behavioral Therapy for Insomnia in Pregnancy
Tomfohr-Madsen, L. M., Clayborne, Z. M., Rouleau, C. R., & Campbell, T. S. (2017) · Behavioral Sleep Medicine · doi:10.1080/15402002.2016.1141769 · Cited by 86
Sanjida, S., McPhail, S. M., Shaw, J., Couper, J., Kissane, D., Price, M. A., & Janda, M. (2018) · Psycho-Oncology · doi:10.1002/pon.4794 · Cited by 74
Vargas, S., Antoni, M. H., Carver, C. S., Lechner, S. C., Wohlgemuth, W., Llabre, M., Blomberg, B. B., Glück, S., & DerHagopian, R. P. (2014) · International Journal of Behavioral Medicine · doi:10.1007/s12529-013-9374-2 · Cited by 64
Walking improves sleep in individuals with cancer: a meta-analysis of randomized, controlled trials
Chiu, H.-Y., Huang, H.-C., Chen, P.-Y., Hou, W.-H., & Tsai, P.-S. (2015) · Oncology Nursing Forum · doi:10.1188/15.onf.e54-e62 · Cited by 63
Ho, F. Y.-Y., Chan, C. S., Lo, W.-Y., & Leung, J. C.-Y. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.01.062 · Cited by 58
Ham, K., Chin, S., Suh, Y. J., Rhee, M., Yu, E.-S., Lee, H. J., Kim, J.-H., Kim, S. W., Koh, S.-J., & Chung, K.-M. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.01592 · Cited by 61
Prevalence and predictors of insomnia in women with invasive ovarian cancer: anxiety a major factor
Price, M. A., Zachariae, R., Butow, P. N., deFazio, A., Chauhan, D., Espie, C. A., Friedlander, M., & Webb, P. M. (2009) · European Journal of Cancer · doi:10.1016/j.ejca.2009.05.030 · Cited by 56
Living with persistent insomnia after cancer: A qualitative analysis of impact and management
Reynolds‐Cowie, P., & Fleming, L. (2021) · British Journal of Health Psychology · doi:10.1111/bjhp.12446 · Cited by 53
Pilot randomized controlled trial of a symptom cluster intervention in advanced cancer.
Wells‐Di Gregorio, S. M., Marks, D. R., DeCola, J., Peng, J., Probst, D., Zaleta, A., Benson, D., Cohn, D. E., Lustberg, M., Carson, W. E., et al. (2019) · Psycho-Oncology · doi:10.1002/pon.4912 · Cited by 52
Nissen, E. R., Neumann, H., Knutzen, S. M., Henriksen, E. N., Amidi, A., Johansen, C., von Heymann, A., Christiansen, P., & Zachariae, R. (2024) · JNCI Cancer Spectrum · doi:10.1093/jncics/pkae041 · Cited by 46
Zeichner, S. B., Zeichner, R. L., Gogineni, K., Shatil, S., & Ioachimescu, O. (2017) · Breast Cancer Basic and Clinical Research · doi:10.1177/1178223417745564 · Cited by 43
Do non-pharmacological sleep interventions affect anxiety symptoms? A meta-analysis
Staines, A. C., Broomfield, N., Pass, L., Orchard, F., & Bridges, J. (2022) · Journal of Sleep Research · doi:10.1111/jsr.13451 · Cited by 43
Management of Cancer-Related Fatigue
Barsevick, A. M., Newhall, T., & Brown, S. (2008) · Clinical Journal of Oncology Nursing · doi:10.1188/08.cjon.s2.21-25 · Cited by 39
Psychological Symptoms in Advanced Cancer
Bail, J. R., Traeger, L., Pirl, W. F., & Bakitas, M. A. (2018) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2018.06.005 · Cited by 34
Cognitive‐Behavioural Therapies in Cancer Care
Horne, D., & Watson, M. (2011) · Handbook of Psychotherapy in Cancer Care · doi:10.1002/9780470975176.ch2 · Cited by 15
Metadata
- Authors
- Savard, J., Simard, S., Ivers, H., & Morin, C. M.
- Venue
- Journal of Clinical Oncology
- Published
- 2005-09-01
- Volume
- 23
- Issue
- 25
- Pages
- 6083-6096
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2107434300
- Cited by
- 505
- References
- 12
- FWCI
- 21.24
- Type
- journal article
- Language
- en
- Open access
- closed
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