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Intermittent Fasting Promotes Fat Loss With Lean Mass Retention, Increased Hypothalamic Norepinephrine Content, and Increased Neuropeptide Y Gene Expression in Diet-Induced Obese Male Mice

Gotthardt, J. D., Verpeut, J. L., Yeomans, B. L., Yang, J., Yasrebi, A., Roepke, T. A., & Bello, N. T. (2015) · Endocrinology · doi:10.1210/en.2015-1622 · Cited by 123 · see citing works

Cinnamaldehyde supplementation prevents fasting‐induced hyperphagia, lipid accumulation, and inflammation in high‐fat diet‐fed mice

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Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat

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Ghrelin and food reward: The story of potential underlying substrates

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Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation

Naznin, F., Toshinai, K., Waise, T. M. Z., NamKoong, C., Moin, A. S. M., Sakoda, H., & Nakazato, M. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0139 · Cited by 102 · see citing works

The modulatory role of high fat feeding on gastrointestinal signals in obesity

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AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis

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Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity

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Ghrelin’s Relationship to Blood Glucose

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Calorie-Restricted Weight Loss Reverses High-Fat Diet-Induced Ghrelin Resistance, Which Contributes to Rebound Weight Gain in a Ghrelin-Dependent Manner

Briggs, D. I., Lockie, S. H., Wu, Q., Lemus, M. B., Stark, R., & Andrews, Z. B. (2013) · Endocrinology · doi:10.1210/en.2012-1421 · Cited by 95 · see citing works

Functional Implications of Limited Leptin Receptor and Ghrelin Receptor Coexpression in the Brain

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Impact of hypothalamic reactive oxygen species in the regulation of energy metabolism and food intake

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Long-chain polyunsaturated fatty acids may mutually benefit both obesity and osteoporosis

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Glucocorticoids, stress and eating: The mediating role of appetite‐regulating hormones

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Alcohol Reward Is Increased after Roux-en-Y Gastric Bypass in Dietary Obese Rats with Differential Effects following Ghrelin Antagonism

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A Stereological Analysis of NPY, POMC, Orexin, GFAP Astrocyte, and Iba1 Microglia Cell Number and Volume in Diet-Induced Obese Male Mice

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Interrelationships between ghrelin, insulin and glucose homeostasis: Physiological relevance

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Hormonal regulation of the hypothalamic melanocortin system

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Ghrelin is neuroprotective in Parkinson’s disease: molecular mechanisms of metabolic neuroprotection

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LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue

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Linking Stress and Infertility: A Novel Role for Ghrelin

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Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice.

Briggs, D. I., Lockie, S., Benzler, J., Wu, Q., Stark, R., Reichenbach, A., Hoy, A., Lemus, M., Coleman, H., Parkington, H., et al. (2014) · Endocrinology · doi:10.1210/en.2013-1861 · Cited by 72 · see citing works

Towards a comprehensive theory of obesity and a healthy diet: The causal role of oxidative stress in food addiction and obesity

Tobore, T. O. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112560 · Cited by 73 · see citing works

Associations of ghrelin with eating behaviors, stress, metabolic factors, and telomere length among overweight and obese women: Preliminary evidence of attenuated ghrelin effects in obesity?

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Ghrelin in obesity and endocrine diseases

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Ghrelin in Obesity, Physiological and Pharmacological Considerations

Álvarez-Castro, P., Pena, L., & Cordido, F. (2013) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557511313040007 · Cited by 70 · see citing works

Physiological roles of ghrelin on obesity

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Enteroendocrine hormones – central effects on behavior

Skibicka, K. P., & Dickson, S. L. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.09.004 · Cited by 69 · see citing works

The Role of Ghrelin in Regulating Synaptic Function and Plasticity of Feeding-Associated Circuits

Serrenho, D., Santos, S. D., & Carvalho, A. L. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00205 · Cited by 61 · see citing works

Neural Responses to Macronutrients: Hedonic and Homeostatic Mechanisms

Tulloch, A. J., Murray, S. M., Vaicekonyte, R., & Avena, N. M. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.12.058 · Cited by 67 · see citing works

Cognitive and neuronal systems underlying obesity

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Ghrelin-Derived Peptides: A Link between Appetite/Reward, GH Axis, and Psychiatric Disorders?

Labarthe, A., Fiquet, O., Hassouna, R., Zizzari, P., Lanfumey, L., Ramoz, N., Grouselle, D., Epelbaum, J., & Tolle, V. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00163 · Cited by 62 · see citing works

Ghrelin, Reward and Motivation

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The role of gastrointestinal vagal afferent fibres in obesity

Kentish, S. J., & Page, A. J. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.278226 · Cited by 63 · see citing works

Hunger and satiety responses to high‐fat meals of varying fatty acid composition in women with obesity

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Gastric Bypass Increases Ethanol and Water Consumption in Diet-Induced Obese Rats

Thanos, P. K., Subrize, M., Delis, F., Cooney, R., Culnan, D. M., Sun, M.-J., Wang, G.-J., Volkow, N., & Hajnal, A. (2012) · Obesity Surgery · doi:10.1007/s11695-012-0749-2 · Cited by 63 · see citing works

The role of leptin and ghrelin in the regulation of appetite in obesity

Skoracka, K., Hryhorowicz, S., Schulz, P., Zawada, A. E., Ratajczak, A. E., Rychter, A. M., Słomski, R., Dobrowolska, A., & Krela‐Kaźmierczak, I. (2025) · Peptides · doi:10.1016/j.peptides.2025.171367 · Cited by 74 · see citing works

Ghrelin Requires p53 to Stimulate Lipid Storage in Fat and Liver

Porteiro, B., Díaz‐Ruiz, A., Martínez, G., Senra, A., Vidal, A., Serrano, M., Gualillo, O., López, M., Malagón, M. M., Diéguez, C., et al. (2013) · Endocrinology · doi:10.1210/en.2013-1176 · Cited by 60 · see citing works

Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis

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Diet-induced obesity causes ghrelin resistance in reward processing tasks

Lockie, S. H., Dinan, T., Lawrence, A. J., Spencer, S. J., & Andrews, Z. B. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.08.004 · Cited by 58 · see citing works

Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task

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Effects of liraglutide in hypothalamic arcuate nucleus of obese mice

Vianna, A. R. D. C. B., Águila, M. B., & Mandarim‐de‐Lacerda, C. A. (2016) · Obesity · doi:10.1002/oby.21387 · Cited by 60 · see citing works

Ghrelin function in human obesity and type 2 diabetes: a concise review

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The brain-adipocyte-gut network: Linking obesity and depression subtypes

Patist, C., Stapelberg, N. J. C., Toit, E. F. D., & Headrick, J. P. (2018) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-018-0626-0 · Cited by 55 · see citing works

Regulation of Memory Function by Feeding-Relevant Biological Systems: Following the Breadcrumbs to the Hippocampus

Suarez, A. N., Noble, E. E., & Kanoski, S. E. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00101 · Cited by 52 · see citing works

The role of ghrelin in weight-regulation disorders: Implications in clinical practice

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Intermittent fasting, adipokines, insulin sensitivity, and hypothalamic neuropeptides in a dietary overload with high-fat or high-fructose diet in mice

Spezani, R., da Silva, R. R., Martins, F. F., Marinho, T. D. S., Águila, M. B., & Mandarim‐de‐Lacerda, C. A. (2020) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2020.108419 · Cited by 51 · see citing works

“A LEAP 2 conclusions? Targeting the ghrelin system to treat obesity and diabetes”

Gupta, D., Ogden, S. B., Shankar, K., Varshney, S., & Zigman, J. M. (2020) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101128 · Cited by 53 · see citing works

Roux-en-Y Gastric Bypass Increases Intravenous Ethanol Self-Administration in Dietary Obese Rats

Polston, J. E., Pritchett, C. E., Tomasko, J. M., Rogers, A. M., Leggio, L., Thanos, P. K., Volkow, N. D., & Hajnal, A. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083741 · Cited by 50 · see citing works

Ghrelin Influences Novelty Seeking Behavior in Rodents and Men

Hansson, C., Shirazi, R. H., Näslund, J., Vogel, H., Neuber, C., Holm, G., Anckarsäter, H. S., Dickson, S. L., Eriksson, E., & Skibicka, K. P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050409 · Cited by 50 · see citing works

Ghrelin, Appetite Regulation, and Food Reward: Interaction with Chronic Stress

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Hypothalamic Dysfunction in Obesity and Metabolic Disorders

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Acylated Ghrelin as a Multi-Targeted Therapy for Alzheimer's and Parkinson's Disease

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Ghrelin Receptor Expression and Colocalization with Anterior Pituitary Hormones Using a GHSR-GFP Mouse Line

Reichenbach, A., Steyn, F. J., Sleeman, M. W., & Andrews, Z. B. (2012) · Endocrinology · doi:10.1210/en.2012-1622 · Cited by 47 · see citing works

A Natural Variant of Obestatin, Q90L, Inhibits Ghrelin's Action on Food Intake and GH Secretion and Targets NPY and GHRH Neurons in Mice

Hassouna, R., Zizzari, P., Viltart, O., Yang, S., Gardette, R., Videau, C., Badoer, E., Epelbaum, J., & Tolle, V. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051135 · Cited by 46 · see citing works

Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals

Freire‐Regatillo, A., Argente-Arizón, P., Argente, J., García‐Segura, L. M., & Chowen, J. A. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00051 · Cited by 45 · see citing works

Experimental Models of Maternal Obesity and Neuroendocrine Programming of Metabolic Disorders in Offspring

Reynolds, C. M., Segovia, S. A., & Vickers, M. H. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00245 · Cited by 46 · see citing works

Olfaction in the context of obesity and diabetes: Insights from animal models to humans

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Diet-Induced Obesity Attenuates Fasting-Induced Hyperphagia

Briggs, D. I., Lemus, M. B., Kua, E. H., & Andrews, Z. B. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02148.x · Cited by 46 · see citing works

A talk between fat tissue, gut, pancreas and brain to control body weight

Wilson, J. L., & Enriori, P. J. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.08.022 · Cited by 45 · see citing works

Effects of Cigarette Smoking on Plasma Concentration of the Appetite-Regulating Peptide Ghrelin

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The role of pancreatic polypeptide in the regulation of energy homeostasis

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Prader–Willi syndrome: From genetics to behaviour, with special focus on appetite treatments

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Leptin reduces food intake via a dopamine D2 receptor-dependent mechanism

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The regulation of gastric ghrelin secretion

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The Good, the Bad and the Unknown Aspects of Ghrelin in Stress Coping and Stress-Related Psychiatric Disorders

Fritz, E. M., Singewald, N., & Bundel, D. D. (2020) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2020.594484 · Cited by 42 · see citing works

The receptive function of hypothalamic and brainstem centres to hormonal and nutrient signals affecting energy balance

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Ablation of ghrelin receptor in leptin-deficient ob/ob mice has paradoxical effects on glucose homeostasis when compared with ablation of ghrelin in ob/ob mice

Ma, X., Lin, Y., Lin, L., Qin, G., Pereira, F. A., Haymond, M. W., Butte, N. F., & Sun, Y. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00576.2011 · Cited by 40 · see citing works

The Role of Ghrelin in Neuroprotection after Ischemic Brain Injury

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Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice.

Briggs, D. I., Lockie, S., Benzler, J., Wu, Q., Stark, R., Reichenbach, A., Hoy, A., Lemus, M., Coleman, H., Parkington, H., et al. (2014) · Endocrinology · doi:10.1210/en.2013-1861 · Cited by 72 · see citing works

Diet-induced obesity causes ghrelin resistance in reward processing tasks

Lockie, S. H., Dinan, T., Lawrence, A. J., Spencer, S. J., & Andrews, Z. B. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.08.004 · Cited by 58 · see citing works

Calorie-Restricted Weight Loss Reverses High-Fat Diet-Induced Ghrelin Resistance, Which Contributes to Rebound Weight Gain in a Ghrelin-Dependent Manner

Briggs, D. I., Lockie, S. H., Wu, Q., Lemus, M. B., Stark, R., & Andrews, Z. B. (2013) · Endocrinology · doi:10.1210/en.2012-1421 · Cited by 95 · see citing works

Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation

Naznin, F., Toshinai, K., Waise, T. M. Z., NamKoong, C., Moin, A. S. M., Sakoda, H., & Nakazato, M. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0139 · Cited by 102 · see citing works

Diet-Induced Obesity Attenuates Fasting-Induced Hyperphagia

Briggs, D. I., Lemus, M. B., Kua, E. H., & Andrews, Z. B. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02148.x · Cited by 46 · see citing works