Obesity effects on depression: systematic review of epidemiological studies
Abstract
Background Obesity is a well-known cause of cardiovascular disease burden and premature death, but effects on psychological morbidity remain uncertain. This article reports findings following a systematic review of epidemiological studies to determine whether obesity causes depression.Methods Multiple databases were searched for English-language studies of etiology of obesity (exposure variable, analyzed as an ordered category) on depression outcomes (dependent variables, continuous or categorical). Studies in children and in women during pregnancy or postpartum were excluded, as were nonrepresentative cross-sectional studies. Searches and identification of studies for inclusion were performed by EA, whereas a descriptive synthesis of important study characteristics was undertaken independently by us.Results We reviewed 24 out of approximately 4500 potentially relevant studies; 4 were prospective cohort studies and 20 were cross-sectional studies (10 from the United States). Effect measures reported in all prospective cohort studies were consistent and suggested that obesity may increase the odds of future depression outcomes (symptoms or nonclinical diagnosis of depression). Effect measures reported in most cross-sectional studies from the United States supported the hypothesized association between obesity and prevalence of depression outcomes for women but not men, in contrast most cross-sectional studies from populations other than the United States consistently failed to find such associations.Conclusions Overall, there is a weak level of evidence supporting the hypothesis that obesity increases the incidence of depression outcomes. Few high-quality prospective cohort studies exist, and cross-sectional studies account for the vast body of published evidence, and therefore firm conclusions for causality cannot yet be drawn. Our finding warrants additional high-quality etiological research on this topic.
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Overweight/obesity and depression/anxiety very often overlap.
“Very often these conditions overlap”
From Mobile Apps for the Management of Comorbid Overweight/Obesity and Depression/Anxiety: A Systematic Review (2020) · cites this paper as [23]
Evidence supports a significant association between anxiety/depression and increased overweight/obesity.
“Evidence, mainly from cross-sectional studies, supports a significant association between anxiety/depression and increased overweight/obesity”
From Mobile Apps for the Management of Comorbid Overweight/Obesity and Depression/Anxiety: A Systematic Review (2020) · cites this paper as [23]
No causal relationship can be inferred between anxiety/depression and overweight/obesity in either direction.
“although no causal relationship can be inferred in either direction [19, 23]”
From Mobile Apps for the Management of Comorbid Overweight/Obesity and Depression/Anxiety: A Systematic Review (2020) · cites this paper as [23]
Cites
Depression and Pain Comorbidity: A Literature Review
Bair, M. J., Robinson, R. L., Katon, W., & Kroenke, K. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.20.2433 · Cited by 3,463 · see citing works
Smoking and Mental Illness: A Population-Based Prevalence Study
Lasser, K., Boyd, J. W., Woolhandler, S., Himmelstein, D. U., McCormick, D., & Bor, D. H. (2000) · JAMA · doi:10.1001/jama.284.20.2606 · Cited by 2,508 · see citing works
Groesz, L. M., Levine, M. P., & Murnen, S. K. (2002) · International Journal of Eating Disorders · doi:10.1002/eat.10005 · Cited by 1,772 · see citing works
Hasin, D. S., Goodwin, R. D., Stinson, F. S., & Grant, B. F. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.10.1097 · Cited by 1,645 · see citing works
Association between obesity and psychiatric disorders in the US adult population
Simon, G. E., Von Korff, M., Saunders, K., Miglioretti, D. L., Crane, P. K., van Belle, G., & Kessler, R. C. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.7.824 · Cited by 1,338 · see citing works
Carpenter, K. M., Hasin, D. S., Allison, D. B., & Faith, M. S. (2000) · American Journal of Public Health · doi:10.2105/ajph.90.2.251 · Cited by 1,018 · see citing works
Depression and cardiac mortality: results from a community-based longitudinal study.
Penninx, B., Beekman, A., Honig, A., Deeg, D., Schoevers, R., van Eijk, J., & van Tilburg, W. V. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.3.221 · Cited by 983 · see citing works
Onyike, C. U. (2003) · American Journal of Epidemiology · doi:10.1093/aje/kwg275 · Cited by 827 · see citing works
Stunkard, A. J., Faith, M. S., & Allison, K. C. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00608-5 · Cited by 820 · see citing works
Physical Activity Reduces the Risk of Subsequent Depression for Older Adults
Strawbridge, W. J. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf047 · Cited by 818 · see citing works
Prospective association between obesity and depression: evidence from the Alameda County Study
Roberts, R. E., Deleger, S., Strawbridge, W. J., & Kaplan, G. A. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802204 · Cited by 674 · see citing works
Are Mood Disorders and Obesity Related? A Review for the Mental Health Professional
McElroy, S. L., Kotwal, R., Malhotra, S., Nelson, E. B., Keck, P. E., & Nemeroff, C. B. (2004) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v65n0507 · Cited by 654 · see citing works
The vital link between chronic disease and depressive disorders.
Chapman, D. P., Perry, G. S., & Strine, T. W. (2005) · Europe PMC (PubMed Central) · Cited by 537 · see citing works
Yanovski, S. Z., Nelson, J. E., Dubbert, B. K., & Spitzer, R. L. (1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.10.1472 · Cited by 497 · see citing works
Obesity and mental disorders in the general population: results from the world mental health surveys
Scott, K. M., Bruffaerts, R., Simon, G. E., Alonso, J., Angermeyer, M. C., de Girolamo, G., Demyttenaere, K., Gasquet, I., Haro, J. M., Karam, E. G., et al. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803701 · Cited by 483 · see citing works
Obesity as Compared With Physical Activity in Predicting Risk of Coronary Heart Disease in Women
Li, T. Y., Rana, J. S., Manson, J. E., Willett, W. C., Stampfer, M. J., Colditz, G. A., Rexrode, K. M., & Hu, F. B. (2006) · Circulation · doi:10.1161/circulationaha.105.574087 · Cited by 472 · see citing works
Are the Obese at Greater Risk for Depression?
Roberts, R. E., Kaplan, G. A., Shema, S. J., & Strawbridge, W. J. (2000) · American Journal of Epidemiology · doi:10.1093/aje/152.2.163 · Cited by 423 · see citing works
Internalization of Weight Bias: Implications for Binge Eating and Emotional Well‐being
Puhl, R., Moss-Racusin, C., & Schwartz, M. (2007) · Obesity · doi:10.1038/oby.2007.521 · Cited by 397 · see citing works
Depression and Cardiovascular Sequelae in Postmenopausal Women
Wassertheil-Smoller, S. W., Shumaker, S. A., Ockene, J. K., Talavera, G. A., Greenland, P., Cochrane, B. B., Robbins, J. A., Aragaki, A. K., & Dunbar‐Jacob, J. M. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.3.289 · Cited by 395 · see citing works
Jolly fat: relation between obesity and psychoneurosis in general population.
Crisp, A. H., & McGuiness, B. (1976) · BMJ · doi:10.1136/bmj.1.6000.7 · Cited by 379 · see citing works
Prevalence and correlates of binge eating disorder in a community sample
Grucza, R. A., Przybeck, T. R., & Cloninger, C. R. (2006) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2006.08.002 · Cited by 379 · see citing works
Body Weight and Mortality Among Men and Women in China
Gu, D. (2006) · JAMA · doi:10.1001/jama.295.7.776 · Cited by 371 · see citing works
Portrayals of Overweight and Obese Individuals on Commercial Television
Greenberg, B. S., Eastin, M. S., Hofschire, L., Lachlan, K. A., & Brownell, K. D. (2003) · American Journal of Public Health · doi:10.2105/ajph.93.8.1342 · Cited by 371 · see citing works
Gupta, A., Silman, A. J., Ray, D. W., Morriss, R. K., Dickens, C. M., Macfarlane, G. J., Chiu, Y. H., Nicholl, B. I., & McBeth, J. (2006) · Lara D. Veeken · doi:10.1093/rheumatology/kel363 · Cited by 361 · see citing works
Depressive Symptoms and Increased Risk of Stroke Mortality Over a 29-Year Period
Everson‐Rose, S. A., ROBERTS, R. E., Goldberg, D. E., & Kaplan, G. A. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.10.1133 · Cited by 355 · see citing works
Depressive mood and obesity in US adults: comparison and moderation by sex, age, and race
Heo, M., Pietrobelli, A., Fontaine, K. R., Sirey, J. A., & Faith, M. S. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803122 · Cited by 331 · see citing works
Obesity and depression: results from the longitudinal Northern Finland 1966 Birth Cohort Study
Herva, A., Laitinen, J. H., Miettunen, J., Veijola, J. M., Karvonen, J. T., Läksy, K., & Joukamaa, M. I. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803174 · Cited by 324 · see citing works
Body Image Partially Mediates the Relationship between Obesity and Psychological Distress
Friedman, K. E., Reichmann, S. K., Costanzo, P. R., & Musante, G. J. (2002) · Obesity Research · doi:10.1038/oby.2002.5 · Cited by 323 · see citing works
Issues in the reporting of epidemiological studies: a survey of recent practice.
Pocock, S. J., Collier, T. J., Dandreo, K. J., de Stavola, B. L., Goldman, M. B., Kalish, L. A., Kasten, L. E., & McCormack, V. A. (2004) · BMJ · doi:10.1136/bmj.38250.571088.55 · Cited by 313 · see citing works
Hu, G., Tuomilehto, J., Silventoinen, K., Barengo, N. C., Peltonen, M., & Jousilahti, P. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0802870 · Cited by 294 · see citing works
Ross, C. E. (1994) · Journal of Health and Social Behavior · doi:10.2307/2137335 · Cited by 278 · see citing works
Medical and psychiatric morbidity in obese women with and without binge eating
Bulik, C. M., Sullivan, P. F., & Kendler, K. S. (2002) · International Journal of Eating Disorders · doi:10.1002/eat.10072 · Cited by 277 · see citing works
Peltonen, M., Lindroos, A. K., & Torgerson, J. (2003) · Pain · doi:10.1016/s0304-3959(03)00091-5 · Cited by 276 · see citing works
Association of obesity with anxiety, depression and emotional well‐being: a community survey
Jorm, A. F., Korten, A. E., Christensen, H., Jacomb, P. A., Rodgers, B., & Parslow, R. A. (2003) · Australian and New Zealand Journal of Public Health · doi:10.1111/j.1467-842x.2003.tb00423.x · Cited by 271 · see citing works
Hc, H., McMillen, R. C., Neaves, T. T., Koch, K., & Cosby, A. G. (2007) · Journal of Pain · doi:10.1016/j.jpain.2006.12.003 · Cited by 268 · see citing works
Bornstein, S. R., Schuppenies, A., Wong, M., & Licinio, J. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001873 · Cited by 267 · see citing works
Obesity, Social Class, and Mental Illness
Moore, M. E. (1962) · JAMA · doi:10.1001/jama.1962.03050370030007 · Cited by 265 · see citing works
Binge eating disorder, weight control self-efficacy, and depression in overweight men and women
Linde, J. A., Jeffery, R. W., Levy, R. L., Sherwood, N. E., Utter, J., Pronk, N. P., & Boyle, R. G. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802570 · Cited by 263 · see citing works
Depressive symptoms in overweight and obese older adults: A test of the “jolly fat” hypothesis
Palinkas, L. A., Wingard, D. L., & Barrett-Connor, E. L. (1996) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(95)00542-0 · Cited by 259 · see citing works
Body weight and psychological distress in NHANES I.
Istvan, J. A., Zavela, K. J., & Weidner, G. (1992) · PubMed · Cited by 251 · see citing works
Karlsson, J., Taft, C., Sjöström, L., Torgerson, J., & Sullivan, M. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802272 · Cited by 238 · see citing works
Fat Stigmatization in Television Shows and Movies: A Content Analysis
Himes, S. M., & Thompson, J. K. (2007) · Obesity · doi:10.1038/oby.2007.635 · Cited by 218 · see citing works
Gluck, M. E., Geliebter, A., Hung, J., & Yahav, E. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000143637.63508.47 · Cited by 202 · see citing works
Association between weight perception and psychological distress
Atlantis, E. E., & Ball, K. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803762 · Cited by 193 · see citing works
Self-citationRoberts Robert, E., Strawbridge, W. J., Stephane, D., & Kaplan, G. A. (2002) · Annals of Behavioral Medicine · doi:10.1207/s15324796abm2403_02 · Cited by 181 · see citing works
Major depression and all-cause mortality among white adults in the United States
Zheng, D., Macera, C. A., Croft, J. B., Giles, W. H., Davis, D. R., & Scott, W. K. (1997) · Annals of Epidemiology · doi:10.1016/s1047-2797(97)00014-8 · Cited by 169 · see citing works
The Relation of Body Mass Index to Depressive Symptoms
Johnston, E., Johnson, S., McLeod, P., & Johnston, M. (2004) · Canadian Journal of Public Health · doi:10.1007/bf03403643 · Cited by 152 · see citing works
Epidemiology of depression and its treatment in the general population
Ohayon, M. M. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.10.006 · Cited by 143 · see citing works
Prevalence of major depressive disorder in the general population of South Korea
Ohayon, M. M., & Hong, S.-C. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2005.02.003 · Cited by 135 · see citing works
Binge Eating, Body Image, Depression, and Self‐Efficacy in an Obese Clinical Population
Cargill, B. R., Clark, M. M., Pera, V., NIAURA, R. S., & Abrams, D. B. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00421.x · Cited by 134 · see citing works
Ljung, T., Holm, G., Friberg, P., Andersson, B., Bengtsson, B., Svensson, J., Dallman, M. F., McEwen, B. S., & Björntorp, P. A. (2000) · Obesity Research · doi:10.1038/oby.2000.61 · Cited by 122 · see citing works
Association of Major Depression and Binge Eating Disorder with Weight Loss in a Clinical Setting
Pagoto, S., Bodenlos, J. S., Kantor, L., Gitkind, M., Curtin, C., & Ma, Y. (2007) · Obesity · doi:10.1038/oby.2007.307 · Cited by 119 · see citing works
Obesity in women in relation to mental illness, social factors and personality traits
Hällström, T., & Noppa, H. (1981) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(81)90093-3 · Cited by 114 · see citing works
Influence of depressive mood on the association of CRP and obesity in 3205 middle aged healthy men
Ladwig, K., Marten‐Mittag, B., Löwel, H., Döring, A., & Köenig, W. (2003) · Brain Behavior and Immunity · doi:10.1016/s0889-1591(03)00056-4 · Cited by 114 · see citing works
Depression and anxiety symptoms in relation to anthropometry and metabolism in men
Ahlberg, A.-C., Ljung, T., Rosmond, R., McEwen, B. S., Holm, G., Åkesson, H. O., & Björntorp, P. A. (2002) · Psychiatry Research · doi:10.1016/s0165-1781(02)00192-0 · Cited by 112 · see citing works
Rohrer, J. E., Pierce, J. R., & Blackburn, C. (2004) · Preventive Medicine · doi:10.1016/j.ypmed.2004.07.003 · Cited by 106 · see citing works
Disabling knee pain – another consequence of obesity: Results from a prospective cohort study
Jinks, C., Jordan, K. P., & Croft, P. R. (2006) · BMC Public Health · doi:10.1186/1471-2458-6-258 · Cited by 104 · see citing works
Crisp, A. H., Queenan, M., Sittampaln, Y., & Harris, G. (1980) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(80)90013-6 · Cited by 87 · see citing works
Depression and pain: an overview
Williams, L. J., Jacka, F. N., Pasco, J. A., Dodd, S., & Berk, M. (2006) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2006.00130.x · Cited by 81 · see citing works
Psychiatric co-morbidities in patients attending specialist obesity services in the UK
Tuthill, A. (2006) · QJM · doi:10.1093/qjmed/hcl041 · Cited by 78 · see citing works
Obesity and depressive symptoms in elderly Japanese: The Tsurugaya Project
Kuriyama, S., Koizumi, Y., Matsuda‐Ohmori, K., Seki, T., Shimazu, T., Hozawa, A., Awata, S., & Tsuji, I. (2006) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2005.07.010 · Cited by 69 · see citing works
How to assess epidemiological studies
ZACCAI, J. H. (2004) · Postgraduate Medical Journal · doi:10.1136/pgmj.2003.012633 · Cited by 66 · see citing works
Larsen, J. K., Geenen, R., van Ramshorst, B., Brand, N., de Wit, P., Stroebe, W., & van Doornen, L. J. P. (2003) · Obesity Surgery · doi:10.1381/096089203322190871 · Cited by 60 · see citing works
Associations between waist circumference and depressive disorders
Hach, I., Ruhl, U. E., Klotsche, J., Klose, M., & Jacobi, F. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.01.023 · Cited by 50 · see citing works
Turley, M. L., Tobias, M. I., & Paul, S. (2006) · Australian and New Zealand Journal of Public Health · doi:10.1111/j.1467-842x.2006.tb00863.x · Cited by 30 · see citing works
Rowston, W., Mccluskey, S., Gazet, J. C., Lacey, J. H., Franks, G. M., & Lynch, D. (1992) · Obesity Surgery · doi:10.1381/096089292765559954 · Cited by 26 · see citing works
Våge, V., Solhaug, J. H., Viste, A., Bergsholm, P., & Wahl, A. K. (2003) · Obesity Surgery · doi:10.1381/096089203322509264 · Cited by 19 · see citing works
John, U., Meyer, C., Rumpf, H., & Hapke, U. (2005) · Psychiatry Research · doi:10.1016/j.psychres.2005.07.011 · Cited by 17 · see citing works
Depression in Association With Severe Obesity
Dixon, J. B., Dixon, M. E., & O'Brien, P. E. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.17.2058 · Cited by 5 · see citing works
Expression of host defense scavenger receptors in spondylarthropathy
McBeth (2001) · Pure Amsterdam UMC · doi:10.1002/1529-0131(200104)44:4 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Child abuse: Adolescent records vs. adult recall
Femina, D. D., Yeager, C. A., & Lewis, D. O. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90033-p · Cited by 8,820 · see citing works
Overweight, Obesity, and Depression: A Systematic Review and Meta-analysis of Longitudinal Studies
Luppino, F. S., de Wit, L. M., Bouvy, P. F., Stijnen, T., Cuijpers, P., Penninx, B. W. J. H., & Zitman, F. G. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.2 · Cited by 4,322 · see citing works
Boehm, J. K., & Kubzansky, L. D. (2012) · Psychological Bulletin · doi:10.1037/a0027448 · Cited by 909 · see citing works
Depression as a disease of modernity: explanations for increasing prevalence
Hidaka, B. H. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.12.036 · Cited by 769 · see citing works
Gariepy, G., Nitka, D., & Schmitz, N. (2010) · International Journal of Obesity · doi:10.1038/ijo.2009.252 · Cited by 753 · see citing works
Depression and anxiety in patients with Inflammatory Bowel Disease: a systematic review
Neuendorf, R., Harding, A., Stello, N., Hanes, D., & Wahbeh, H. (2016) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2016.06.001 · Cited by 561 · see citing works
Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity
Bruce-Keller, A. J., Salbaum, J. M., Luo, M., Blanchard, E., Taylor, C. M., Welsh, D. A., & Berthoud, H.-R. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.07.012 · Cited by 563 · see citing works
Sex differences in the physiology of eating
Asarian, L., & Geary, N. (2013) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00446.2012 · Cited by 513 · see citing works
Compulsive exercise and eating disorders
Meyer, C., Taranis, L., Goodwin, H., & Haycraft, E. (2011) · European Eating Disorders Review · doi:10.1002/erv.1122 · Cited by 433 · see citing works
Oxidative & nitrosative stress in depression: Why so much stress?
Moylan, S., Berk, M., Dean, O. M., Samuni, Y., Williams, L. J., O'Neil, A. E., Hayley, A. C., Pasco, J. A., Anderson, G., Jacka, F. N., et al. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.05.007 · Cited by 401 · see citing works
Cairns, K. E., Yap, M. B. H., Pilkington, P. D., & Jorm, A. F. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.08.006 · Cited by 363 · see citing works
Psychiatric disorders and obesity: A review of association studies
Rajan, T., & Menon, V (2017) · Journal of Postgraduate Medicine · doi:10.4103/jpgm.jpgm_712_16 · Cited by 346 · see citing works
Evidence for prospective associations among depression and obesity in population‐based studies
Faith, M. S., Butryn, M., Wadden, T. A., Fabricatore, A., Nguyen, A. M., & Heymsfield, S. B. (2011) · Obesity Reviews · doi:10.1111/j.1467-789x.2010.00843.x · Cited by 340 · see citing works
Pereira-Miranda, E., Costa, P. R. F., Queiroz, V. A. O., Pereira-Santos, M., & Santana, M. L. P. (2017) · Journal of the American College of Nutrition · doi:10.1080/07315724.2016.1261053 · Cited by 335 · see citing works
Diet-Induced Obesity Causes Ghrelin Resistance in Arcuate NPY/AgRP Neurons
Briggs, D. I., Enriori, P. J., Lemus, M. B., Cowley, M. A., & Andrews, Z. B. (2010) · Endocrinology · doi:10.1210/en.2010-0556 · Cited by 320 · see citing works
A systematic review of variables associated with the relationship between obesity and depression.
Preiss, K., Brennan, L., & Clarke, D. (2013) · Obesity Reviews · doi:10.1111/obr.12052 · Cited by 285 · see citing works
Mannan, M., Mamun, A., Doi, S., & Clavarino, A. (2016) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2015.12.008 · Cited by 280 · see citing works
Arcelus, J., Haslam, M., Farrow, C., & Meyer, C. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.10.009 · Cited by 276 · see citing works
Bidirectional association between depression and obesity in middle–aged and older women
Pan, A., Sun, Q., Czernichow, S., Kivimaki, M., Okereke, O. I., Lucas, M., Manson, J. E., Ascherio, A., & Hu, F. B. (2012) · International Journal of Obesity · doi:10.1038/ijo.2011.111 · Cited by 264 · see citing works
Shelton, R. C., & Miller, A. H. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.04.004 · Cited by 257 · see citing works
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES
Baru, P. C. R. (2014) · ADVANCED SCIENCES INDEX · Cited by 236 · see citing works
Rao, W., Zong, Q.-Q., Zhang, J.-W., An, F., Jackson, T., Ungvari, G. S., Xiang, Y., Su, Y.-Y., D’Arcy, C., & Xiang, Y. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.01.154 · Cited by 211 · see citing works
Konttinen, H., Silventoinen, K., Sarlio-Lähteenkorva, S., Männistö, S., & Haukkala, A. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29732 · Cited by 189 · see citing works
Wang, S., Sun, Q., Zhai, L., Bai, Y., Wei, W., & Jia, L. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16030340 · Cited by 164 · see citing works
Oksanen, T., Kouvonen, A. M., Vahtera, J., Virtanen, M., & Mika Kivimaki, B. (2009) · Journal of Epidemiology & Community Health · doi:10.1136/jech.2008.086074 · Cited by 164 · see citing works
Obesity Is Associated With Inferior Results After Surgery for Lumbar Spinal Stenosis
Knutsson, B., Michaëlsson, K., & Sandén, B. (2012) · Spine · doi:10.1097/brs.0b013e318270b243 · Cited by 163 · see citing works
Ma, J., & Xiao, L. (2009) · Obesity · doi:10.1038/oby.2009.213 · Cited by 157 · see citing works
Vogelzangs, N., Kritchevsky, S. B., Beekman, A. T. F., Brenes, G. A., Newman, A. B., Satterfield, S., Yaffe, K., Harris, T. B., Penninx, B. W. J. H., & Study, H. A. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04743blu · Cited by 155 · see citing works
Ferreira, A. P. D. S., Szwarcwald, C. L., & Damacena, G. N. (2019) · Revista Brasileira de Epidemiologia · doi:10.1590/1980-549720190024 · Cited by 153 · see citing works
Inflammation in depression: is adiposity a cause?
Shelton, R. C., & Miller, A. H. (2011) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2011.13.1/rshelton · Cited by 143 · see citing works
Xu, Q., Anderson, D., & Lurie-Beck, J. (2011) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2011.04.007 · Cited by 136 · see citing works
Mika Kivimaki, B., Lawlor, D. A., Singh‐Manoux, A., Batty, G. D., Ferrie, J. E., Shipley, M. J., Nabi, H., Sabia, S., Marmot, M. G., & Jokela, M. M. (2009) · BMJ · doi:10.1136/bmj.b3765 · Cited by 133 · see citing works
The Second Brain: Is the Gut Microbiota a Link Between Obesity and Central Nervous System Disorders?
Ochoa‐Repáraz, J., & Kasper, L. H. (2016) · Current Obesity Reports · doi:10.1007/s13679-016-0191-1 · Cited by 134 · see citing works
Clinical problems caused by obesity
Kyrou, I., Randeva, H. S., Barber, T., Tsigos, C., Kaltsas, G. A., & Weickert, M. O. (2022) · Warwick Research Archive Portal (University of Warwick) · doi:10.82444/warw.33841351 · Cited by 127 · see citing works
Associations Between Serum Lipids and Major Depressive Disorder
Dortland, A. K. B. V. R., Giltay, E. J., van Veen, T., PELT, J. V., Zitman, F. G., & Penninx, B. W. J. H. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04865blu · Cited by 127 · see citing works
Obesity and Internalized Weight Stigma: A Formulation Model for an Emerging Psychological Problem
Ratcliffe, D., & Ellison, N. (2013) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465813000763 · Cited by 122 · see citing works
Obesity – A neuropsychological disease? Systematic review and neuropsychological model
Jauch‐Chara, K., & Oltmanns, K. M. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.12.001 · Cited by 121 · see citing works
Depression and Insulin Resistance
Pearson, S., Schmidt, M., Patton, G. C., Dwyer, T., Blizzard, L., Otáhal, P., & Venn, A. (2010) · Diabetes Care · doi:10.2337/dc09-1940 · Cited by 122 · see citing works
Lewis, S. C., Thomas, S. L., Hyde, J., Castle, D. J., Blood, R. W., & Komesaroff, P. A. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-309 · Cited by 119 · see citing works
Obesity and depression in adolescence and beyond: Reciprocal risks
Marmorstein, N. R., Iacono, W., & Legrand, L. N. (2014) · International Journal of Obesity · doi:10.1038/ijo.2014.19 · Cited by 121 · see citing works
Perceived weight, not obesity, increases risk for major depression among adolescents
ROBERTS, R. E., & Duong, H. T. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.03.019 · Cited by 112 · see citing works
Overweight and Obesity in Childhood and Risk of Mental Disorder: a 20-Year Cohort Study
Sanderson, K. A., Patton, G. C., McKercher, C., Dwyer, T., & Venn, A. (2011) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048674.2011.570309 · Cited by 104 · see citing works
Trajectories of Change in Obesity and Symptoms of Depression: The CARDIA Study
Needham, B. L., Epel, E. S., Adler, N. E., & Kiefe, C. I. (2010) · American Journal of Public Health · doi:10.2105/ajph.2009.172809 · Cited by 103 · see citing works
McCrea, R. L., Berger, Y. G., & King, M. B. (2012) · International Journal of Obesity · doi:10.1038/ijo.2011.65 · Cited by 101 · see citing works
Obesity might not be a risk factor for female sexual dysfunction
Kadıoğlu, P., Yetkin, D. Ö., Şanlı, Ö., Yalin, A. S., Önem, K., & Kadıoğlu, A. (2010) · British Journal of Urology · doi:10.1111/j.1464-410x.2010.09348.x · Cited by 99 · see citing works
Is depression associated with health risk-related behaviour clusters in adults?
Verger, P., Lions, C., & Ventelou, B. (2009) · European Journal of Public Health · doi:10.1093/eurpub/ckp057 · Cited by 98 · see citing works
Body Image, Food Addiction, Depression, and Body Mass Index in University Students
Şanlıer, N., Ağagündüz, D., & Toka, O. (2016) · Ecology of Food and Nutrition · doi:10.1080/03670244.2016.1219951 · Cited by 96 · see citing works
Soft drink consumption and mental health problems among adults in Australia
Shi, Z., Taylor, A. W., Wittert, G., Goldney, R. D., & Gill, T. K. (2010) · Public Health Nutrition · doi:10.1017/s1368980009993132 · Cited by 95 · see citing works
Night eating syndrome: implications for severe obesity
Cleator, J., Abbott, J., Judd, P. A., Sutton, C., & Wilding, J. P. H. (2012) · Nutrition and Diabetes · doi:10.1038/nutd.2012.16 · Cited by 94 · see citing works
Association between common mental disorder and obesity over the adult life course.
Kivimäki, M., Batty, G. D., Singh-Manoux, A., Nabi, H., Sabia, S., Tabak, A. G., Akbaraly, T. N., Vahtera, J., Marmot, M. G., & Jokela, M. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.108.057299 · Cited by 90 · see citing works
The complex spectrum of forensic issues arising from obesity
Byard, R. W. (2012) · Forensic Science Medicine and Pathology · doi:10.1007/s12024-012-9322-5 · Cited by 86 · see citing works
Lang, C. J., Appleton, S., Vakulin, A., McEvoy, R. D., Vincent, A. D., Wittert, G., Martin, S., Grant, J. F., Taylor, A. W., Antic, N. A., et al. (2017) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.6546 · Cited by 87 · see citing works
Depression and obesity: do shared genes explain the relationship?
Afari, N., Noonan, C., Goldberg, J. H., Roy‐Byrne, P., Schur, E. A., Golnari, G., & Buchwald, D. (2010) · Depression and Anxiety · doi:10.1002/da.20704 · Cited by 83 · see citing works
Bloem, B., Xu, L., Morava, É., Faludi, G., Palkovits, M., Roubos, E. W., & Kozicz, T. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.07.023 · Cited by 80 · see citing works
Garip, G., & Yardley, L. (2011) · Clinical Obesity · doi:10.1111/j.1758-8111.2011.00021.x · Cited by 80 · see citing works
Diabesity and mood disorders: Multiple links through the microbiota-gut-brain axis
Farzi, A., Hassan, A. M., Zenz, G., & Holzer, P. D. (2018) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2018.11.003 · Cited by 77 · see citing works
Mika Kivimaki, B., Jokela, M. M., Hamer, M., Geddes, J. R., Ebmeier, K. P., Meena Kumari, B., Singh‐Manoux, A., Hingorani, A. D., & Batty, G. D. (2011) · American Journal of Epidemiology · doi:10.1093/aje/kwq444 · Cited by 78 · see citing works
Marx, P., Antal, P., Bolgár, B., Bagdy, G., Deakin, J. F. W., & Juhász, G. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005487 · Cited by 77 · see citing works
Geoffroy, M., Li, L., & Power, C. (2014) · Psychological Medicine · doi:10.1017/s0033291714000142 · Cited by 74 · see citing works
Zhang, L., Liu, K., Li, H., Li, D., Chen, Z., Zhang, L.-L., & Guo, L. (2016) · BMC Public Health · doi:10.1186/s12889-016-3864-5 · Cited by 74 · see citing works
Antenatal and postnatal depression in women with obesity: a systematic review
Steinig, J., Nagl, M., Linde, K., Zietlow, G., & Kersting, A. (2017) · Archives of Women s Mental Health · doi:10.1007/s00737-017-0739-4 · Cited by 75 · see citing works
Robinson, E., Roberts, C. A., Vainik, U., & Jones, A. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.10.009 · Cited by 77 · see citing works
A Prospective Study of Psychological Distress and Weight Status in Adolescents/Young Adults
Kubzansky, L. D., Gilthorpe, M. S., & Goodman, E. (2011) · Annals of Behavioral Medicine · doi:10.1007/s12160-011-9323-8 · Cited by 73 · see citing works
Meegan, A. P., Perry, I. J., & Phillips, C. M. (2017) · Nutrients · doi:10.3390/nu9030238 · Cited by 73 · see citing works
Hidese, S., Asano, S., Saito, K., Sasayama, D., & Kunugi, H. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.02.009 · Cited by 71 · see citing works
Gariepy, G., Wang, J., Lesage, A. D., & Schmitz, N. (2010) · Obesity · doi:10.1038/oby.2009.333 · Cited by 70 · see citing works
Lawlor, D. A., Harbord, R. M., Tybjærg‐Hansen, A., Palmer, T., Zacho, J., Benn, M., Timpson, N. J., Smith, G. D., & Nordestgaard, B. G. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2011.02343.x · Cited by 69 · see citing works
Sobolewska-Nowak, J., Wachowska, K., Nowak, A., Orzechowska, A., Szulc, A., Płaza, O., & Gałecki, P. (2023) · Biomedicines · doi:10.3390/biomedicines11071903 · Cited by 72 · see citing works
Merikangas, A. K., Mendola, P., Pastor, P. N., Reuben, C. A., & Cleary, S. D. (2011) · Journal of Behavioral Medicine · doi:10.1007/s10865-011-9340-x · Cited by 67 · see citing works
The Association between Adiposity, Mental Well-Being, and Quality of Life in Extreme Obesity
Jagielski, A. C., Brown, A. C., Araghi, M., Thomas, G. N., & Taheri, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092859 · Cited by 65 · see citing works
Haynes, A., Kersbergen, I., Sutin, A. R., Daly, M., & Robinson, E. (2019) · Clinical Psychology Review · doi:10.1016/j.cpr.2019.101753 · Cited by 64 · see citing works
A Prospective Study of Fitness, Fatness, and Depressive Symptoms
Becofsky, K. M., Sui, X., Lee, D.-C., Wilcox, S., Zhang, J., & Blair, S. N. (2015) · American Journal of Epidemiology · doi:10.1093/aje/kwu330 · Cited by 64 · see citing works
Childhood and Young Adult Overweight/Obesity and Incidence of Depression in the SUN Project
Sánchez‐Villegas, A., Pimenta, A. M., Beunza, J. J., Guillén‐Grima, F., Toledo, E., & Martínez‐González, M. Á. (2009) · Obesity · doi:10.1038/oby.2009.375 · Cited by 63 · see citing works
The impact of sleep, stress, and depression on postpartum weight retention: A systematic review
Xiao, R. S., Kroll-Desrosiers, A. R., Goldberg, R. J., Pagoto, S. L., Person, S. D., & Waring, M. E. (2014) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2014.09.016 · Cited by 62 · see citing works
Obesity and onset of depression among U.S. middle-aged and older adults
Xiang, X., & An, R. (2014) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2014.12.008 · Cited by 64 · see citing works
Depressive symptoms are associated with weight gain among women
Sutin, A. R., & Zonderman, A. B. (2012) · Psychological Medicine · doi:10.1017/s0033291712000566 · Cited by 62 · see citing works
Suglia, S. F., Demmer, R. T., Wahi, R., Keyes, K. M., & Koenen, K. C. (2016) · American Journal of Epidemiology · doi:10.1093/aje/kwv149 · Cited by 63 · see citing works
Adherence to the obesity-related lifestyle intervention targets in the IDEFICS study
on behalf of the IDEFICS consortium, Kovács, E., Siani, A., Konstabel, K., Hadjigeorgiou, C., de Bourdeaudhuij, I., Eiben, G., Lissner, L., Gwozdz, W., Reisch, L., et al. (2014) · International Journal of Obesity · doi:10.1038/ijo.2014.145 · Cited by 59 · see citing works
Yu, N., Chen, C.-Y., Liu, C.-Y., Chau, Y., & Chang, C. (2011) · PubMed · Cited by 59 · see citing works
Shi, Z., Grande, E. D., Taylor, A. W., Gill, T. K., Adams, R., & Wittert, G. (2011) · Respirology · doi:10.1111/j.1440-1843.2011.02115.x · Cited by 57 · see citing works
Mindfulness and eating behaviour styles in morbidly obese males and females
Ouwens, M. A., Schiffer, A. A., Visser, L. I., Raeijmaekers, N. J. C., & Nyklíček, I. (2015) · Appetite · doi:10.1016/j.appet.2014.11.030 · Cited by 56 · see citing works
Chaiton, M., Sabiston, C. M., O’Loughlin, J. L., McGrath, J. J., Maximova, K., & Lambert, M. A. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.43 · Cited by 56 · see citing works
Childhood traumatic stress and obesity in women: The intervening effects of PTSD and MDD
Dedert, E. A., Becker, M. E., Fuemmeler, B. F., Braxton, L. E., Calhoun, P. S., & Beckham, J. C. (2010) · Journal of Traumatic Stress · doi:10.1002/jts.20584 · Cited by 55 · see citing works
Racial and Ethnic Differences in the Association Between Obesity and Depression in Women
Hicken, M. T., Lee, H. E., Mezuk, B. R., Kershaw, K. N., Rafferty, J. A., & Jackson, J. S. (2013) · Journal of Women s Health · doi:10.1089/jwh.2012.4111 · Cited by 54 · see citing works
The relationship between depressive symptoms among female workers and job stress and sleep quality
Cho, H.-S., Kim, Y.-W., Park, H.-W., Lee, K.-H., Jeong, B., Kang, Y.-S., & Park, K. (2013) · Annals of Occupational and Environmental Medicine · doi:10.1186/2052-4374-25-12 · Cited by 55 · see citing works
Adolescent Obesity and Future College Degree Attainment
Fowler‐Brown, A. G., Ngo, L. H., Phillips, R. S., & Wee, C. C. (2009) · Obesity · doi:10.1038/oby.2009.463 · Cited by 53 · see citing works
Longitudinal associations between depressive symptoms and body mass index in a 20-year follow-up
Konttinen, H. M., Kiviruusu, O. H., Huurre, T. M., Haukkala, A., Aro, H., & MARTTUNEN, M. J. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.151 · Cited by 55 · see citing works
The brain-adipocyte-gut network: Linking obesity and depression subtypes
Patist, C., Stapelberg, N. J. C., Toit, E. F. D., & Headrick, J. P. (2018) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-018-0626-0 · Cited by 55 · see citing works
Obesity, mental health, and sexual dysfunction: A critical review
Esfahani, S. B., & Pal, S. (2018) · Health Psychology Open · doi:10.1177/2055102918786867 · Cited by 56 · see citing works
Claesson, I., Josefsson, A., & Sydsjö, G. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-766 · Cited by 52 · see citing works
Simon, G. E., Rohde, P., Ludman, E. J., Jeffery, R. W., Linde, J. A., Operskalski, B. H., & Arterburn, D. E. (2010) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2010.09.010 · Cited by 51 · see citing works
Weight, gender, and depressive symptoms in S outh K orea
Brewis, A., Han, S., & SturtzSreetharan, C. (2017) · American Journal of Human Biology · doi:10.1002/ajhb.22972 · Cited by 51 · see citing works
Brugha, T. S., Matthews, R. J., Morgan, Z., Hill, T., Alonso, J., & Jones, D. R. H. (2012) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.111.098103 · Cited by 50 · see citing works
WNK Kinases, Renal Ion Transport and Hypertension
San‐Cristobal, P., Heros, P. D. L., Ponce‐Coria, J., Moreno, E., & Gamba, G. (2008) · American Journal of Nephrology · doi:10.1159/000139639 · Cited by 47 · see citing works
Effects of thyroid hormone and depression on common components of central obesity
Du, F.-M., Kuang, H., Duan, B., Liu, D., & Yu, X. (2019) · Journal of International Medical Research · doi:10.1177/0300060519851624 · Cited by 49 · see citing works
Outcomes of bariatric surgery in patients with depression disorders
Susmallian, S., Nikiforova, I., Azoulai, S., & Barnea, R. (2019) · PLoS ONE · doi:10.1371/journal.pone.0221576 · Cited by 47 · see citing works
Geldsetzer, P., Vaikath, M., Wagner, R. G., Rohr, J. K., Montana, L. S., Gómez-Olivé, F. X., Rosenberg, M. S., Manne‐Goehler, J., Mateen, F. J., Payne, C., et al. (2018) · The Journals of Gerontology Series A · doi:10.1093/gerona/gly145 · Cited by 52 · see citing works
Obesity and depression or anxiety
Atlantis, E. E., Goldney, R. D., & Wittert, G. (2009) · BMJ · doi:10.1136/bmj.b3868 · Cited by 49 · see citing works
Self-citationDepressive symptoms, anxiety and well-being among metabolic health obese subtypes
Phillips, C. M., & Perry, I. J. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.07.168 · Cited by 48 · see citing works
Body mass index and depressive symptoms: instrumental‐variables regression with genetic risk score
Jokela, M. M., Elovainio, M. J., Keltikangas‐Järvinen, L., Batty, G. D., Hintsanen, M., Seppälä, I., Kähönen, M. A. P., Viikari, J. S. A., Raitakari, O. T., Lehtimäki, T. J., et al. (2012) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2012.00846.x · Cited by 48 · see citing works
- Authors
- Atlantis, E., & Baker, M.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Atlantis, E
- ORCID
- Venue
- International Journal of Obesity
- Published
- 2008-04-15
- Volume
- 32
- Issue
- 6
- Pages
- 881-891
- ISSN
- 0307-0565 (ISSN-L)
- 1476-5497
- OpenAlex
- W2056014734
- Cited by
- 399
- References
- 70
- Citations by year
- 2026: 11 · 2025: 10 · 2024: 13 · 2023: 7 · 2022: 12 · 2021: 13 · 2020: 20 · 2019: 15 · 2018: 25 · 2017: 29 · 2016: 39 · 2015: 26 · 2014: 32 · 2013: 25 · 2012: 26
- FWCI
- 4.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- International Journal of Obesity (publishedVersion)
- PubMed (publishedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Health Professions › Pharmacy › Obesity and Health Practices
- Keywords
- obesity, depression, psychological morbidity, depression incidence, sex differences, etiology of depression, cross-sectional study, prospective cohort
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Depressive Disorder, Female, Humans, Male, Middle Aged, Obesity, Self Concept, Severity of Illness Index, Sex Factors, Stress, Psychological, Prevalence, Epidemiologic Studies, Databases, Bibliographic
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