Androgen Receptor (AR) Coregulators: A Diversity of Functions Converging on and Regulating the AR Transcriptional Complex

The Role of Chromatin during Transcription

Li, B., Carey, M., & Workman, J. L. (2007) · Cell · doi:10.1016/j.cell.2007.01.015 · Cited by 3,503 · see citing works

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

Tsai, M., & O’Malley, B. W. (1994) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.63.070194.002315 · Cited by 2,887 · see citing works

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

Spada, A. L., Wilson, E. M., Lubahn, D. B., Harding, A., & Fischbeck, K. (1991) · Nature · doi:10.1038/352077a0 · Cited by 2,801 · see citing works

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

Oñate, S., Tsai, S., Tsai, M.-J., & O'Malley, B. (1995) · Science · doi:10.1126/science.270.5240.1354 · Cited by 2,507 · see citing works

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

Heery, D. M., Kalkhoven, E., Hoare, S., & Parker, M. G. (1997) · Nature · doi:10.1038/42750 · Cited by 2,128 · see citing works

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

Metzger, E., Wissmann, M., Yin, N., Müller, J. M., Schneider, R., Peters, A. H. F. M., Günther, T., Buettner, R., & Schüle, R. (2005) · Nature · doi:10.1038/nature04020 · Cited by 1,741 · see citing works

Androgen Receptor Defects: Historical, Clinical, and Molecular Perspectives*

Quigley, C. A., Bellis, A. D., Marschke, K. B., Awady, M. K. E., Wilson, E. M., & French, F. S. (1995) · Endocrine Reviews · doi:10.1210/edrv-16-3-271 · Cited by 1,436 · see citing works

Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling

Mukhopadhyay, D., & Riezman, H. (2007) · Science · doi:10.1126/science.1127085 · Cited by 1,221 · see citing works

Regulation of Transcription by a Protein Methyltransferase

Chen, D., Ma, H., Hong, H., Koh, S. S., Huang, S., Schurter, B. T., Aswad, D. W., & Stallcup, M. R. (1999) · Science · doi:10.1126/science.284.5423.2174 · Cited by 1,214 · see citing works

Steroid 5α-reductase: two genes/two enzymes

Russell, D. W., & Wilson, J. D. (1994) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.63.070194.000325 · Cited by 1,105 · see citing works

The role of general initiation factors in transcription by RNA polymerase II

ROEDER, R. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10050-5 · Cited by 1,009 · see citing works

Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

Rosenfeld, M. G., Lunyak, V. V., & Glass, C. K. (2006) · Genes & Development · doi:10.1101/gad.1424806 · Cited by 952 · see citing works

Androgen Receptor (AR) Coregulators: An Overview

Heinlein, C. A., & Chang, C. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.2.0460 · Cited by 943 · see citing works

Coregulator Function: A Key to Understanding Tissue Specificity of Selective Receptor Modulators

Smith, C. L., & O’Malley, B. W. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0023 · Cited by 931 · see citing works

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

Giovannucci, E. L., Stampfer, M. J., Krithivas, K., Brown, M. A., Brufsky, A., Talcott, J. A., Hennekens, C. H., & Kantoff, P. W. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.3320 · Cited by 872 · see citing works

JHDM2A, a JmjC-Containing H3K9 Demethylase, Facilitates Transcription Activation by Androgen Receptor

Yamane, K., Toumazou, C., Tsukada, Y.-I., Erdjument‐Bromage, H., Tempst, P., Wong, J., & Zhang, Y. (2006) · Cell · doi:10.1016/j.cell.2006.03.027 · Cited by 840 · see citing works

The nuclear receptor ligand-binding domain: structure and function

Moras, D., & Gronemeyer, H. (1998) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(98)80015-x · Cited by 838 · see citing works

Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor

Wang, H., Huang, Z., Li, X., Feng, Q. F., Erdjument‐Bromage, H., Strahl, B. D., Briggs, S. D., Allis, C. D., Wong, J., Tempst, P., et al. (2001) · Science · doi:10.1126/science.1060781 · Cited by 806 · see citing works

A Steroid Receptor Coactivator, SRA, Functions as an RNA and Is Present in an SRC-1 Complex

Lanz, R. B., McKenna, N. J., Oñate, S. A., Albrecht, U., Wong, J., Tsai, S. Y., Tsai, M., & O’Malley, B. W. (1999) · Cell · doi:10.1016/s0092-8674(00)80711-4 · Cited by 794 · see citing works

Androgen production in women

Burger, H. G. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)02985-0 · Cited by 771 · see citing works

GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

Hong, H., Kohli, K. K., Trivedi, A. A., Johnson, D. L., & Stallcup, M. R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.10.4948 · Cited by 694 · see citing works

A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth

Wang, Q., Li, W., Liu, X. S., Carroll, J. S., Jänne, O. A., Keeton, E. K., Chinnaiyan, A. M., Pienta, K. J., & Brown, M. A. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.05.041 · Cited by 689 · see citing works

Partial Hormone Resistance in Mice with Disruption of the Steroid Receptor Coactivator-1 (SRC-1) Gene

Xu, J., Qiu, Y., DeMayo, F. J., Tsai, S. Y., Tsai, M., & O’Malley, B. W. (1998) · Science · doi:10.1126/science.279.5358.1922 · Cited by 680 · see citing works

Formation of the Androgen Receptor Transcription Complex

Shang, Y., Myers, M., & Brown, M. A. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00471-9 · Cited by 673 · see citing works

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

Yeh, S., & Chang, C. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5517 · Cited by 632 · see citing works

Structural Evidence for Ligand Specificity in the Binding Domain of the Human Androgen Receptor

Matias, P. M., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004571200 · Cited by 608 · see citing works

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

Wissmann, M., Yin, N., Müller, J. M., Greschik, H., Fodor, B. D., Jenuwein, T., Vogler, C., Schneider, R., Günther, T., Buettner, R., et al. (2007) · Nature Cell Biology · doi:10.1038/ncb1546 · Cited by 602 · see citing works

Mechanisms of Androgen-Refractory Prostate Cancer

Debes, J. D., & Tindall, D. J. (2004) · New England Journal of Medicine · doi:10.1056/nejmp048178 · Cited by 558 · see citing works

GRIP1, a Transcriptional Coactivator for the AF-2 Transactivation Domain of Steroid, Thyroid, Retinoid, and Vitamin D Receptors

Hong, H., Kohli, K. K., Garabedian, M. J., & Stallcup, M. R. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.5.2735 · Cited by 553 · see citing works

Androgen Receptor Signaling in Androgen-Refractory Prostate Cancer

Grossmann, M. E., Huang, H., & Tindall, D. J. (2001) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/93.22.1687 · Cited by 548 · see citing works

Review of the in Vivo Functions of the p160 Steroid Receptor Coactivator Family

Xu, J., & Li, Q. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0116 · Cited by 493 · see citing works

Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone

Sack, J. S., Kish, K. F., Wang, C., Attar, R. M., Kiefer, S. E., An, Y., Wu, G. Y., Scheffler, J. E., Salvati, M. E., Krystek, S. R., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081565498 · Cited by 491 · see citing works

Testosterone and Dihydrotestosterone Tissue Levels in Recurrent Prostate Cancer

Titus, M. A., Schell, M. J., Lih, F. B., Tomer, K. B., & Mohler, J. L. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-05-0525 · Cited by 488 · see citing works

Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1)

Poukka, H., Karvonen, U., Jänne, O. A., & Palvimo, J. J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.26.14145 · Cited by 459 · see citing works

Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking

Wang, Q., Carroll, J. S., & Brown, M. A. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.07.018 · Cited by 450 · see citing works

Phosphorylation‐dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

Lin, H.-K., Wang, L., Hu, Y., Altuwaijri, S., & Chang, C. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf406 · Cited by 450 · see citing works

FXXLF and WXXLF Sequences Mediate the NH2-terminal Interaction with the Ligand Binding Domain of the Androgen Receptor

He, B., Kemppainen, J., & Wilson, E. M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002807200 · Cited by 441 · see citing works

Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities

Ding, X. F., Anderson, C. M., Ma, H., Hong, H., Uht, R. M., Kushner, P. J., & Stallcup, M. R. (1998) · Molecular Endocrinology · doi:10.1210/mend.12.2.0065 · Cited by 434 · see citing works

Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)

Reyes, J. C., Barra, J., Muchardt, C., Camus, A., Babinet, C., & Yaniv, M. (1998) · The EMBO Journal · doi:10.1093/emboj/17.23.6979 · Cited by 433 · see citing works

PIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases

Kotaja, N., Karvonen, U., Jänne, O. A., & Palvimo, J. J. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.14.5222-5234.2002 · Cited by 426 · see citing works

The AF1 and AF2 Domains of the Androgen Receptor Interact with Distinct Regions of SRC1

Bevan, C. L., Hoare, S., Claessens, F., Heery, D. M., & Parker, M. G. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.12.8383 · Cited by 424 · see citing works

Identification of two transcription activation units in the N-terminal domain of the human androgen receptor

Jenster, G., van der Korput, H. A. G. M., Trapman, J., & Brinkmann, A. O. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.13.7341 · Cited by 419 · see citing works

Role of Endocytosis in Cellular Uptake of Sex Steroids

Hammes, A., Andreassen, T. K., Spoelgen, R., Raila, J., Hubner, N., Schulz, H., Metzger, J., Schweigert, F. J., Luppa, P. B., Nykjaer, A., et al. (2005) · Cell · doi:10.1016/j.cell.2005.06.032 · Cited by 413 · see citing works

p300 and p300/cAMP-response Element-binding Protein-associated Factor Acetylate the Androgen Receptor at Sites Governing Hormone-dependent Transactivation

Fu, M., Wang, C., Reutens, A. T., Wang, J., Angeletti, R. H., Siconolfi-Baez, L., Ogryzko, V. V., Avantaggiati, M. L., & Pestell, R. G. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m000660200 · Cited by 409 · see citing works

Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter

Cleutjens, K. B. J. M., Eekelen, C. C. E.-V., van der Korput, H. A. G. M., Brinkmann, A. O., & Trapman, J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.11.6379 · Cited by 408 · see citing works

Structural basis of androgen receptor binding to selective androgen response elements

Shaffer, P. L., Jivan, A., Dollins, D. E., Claessens, F., & Gewirth, D. T. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401123101 · Cited by 400 · see citing works

Sexual hormones in human skin

Zouboulis, C., Chen, W.-C., Thornton, M., Qin, K., & Rosenfield, R. (2007) · Hormone and Metabolic Research · doi:10.1055/s-2007-961807 · Cited by 379 · see citing works

An Androgen Response Element in a Far Upstream Enhancer Region Is Essential for High, Androgen-Regulated Activity of the Prostate-Specific Antigen Promoter

Cleutjens, K. B. J. M., van der Korput, H. A. G. M., Eekelen, C. C. E.-V., van Rooij, H. C. J., Faber, P. W., & Trapman, J. (1997) · Molecular Endocrinology · doi:10.1210/mend.11.2.9883 · Cited by 375 · see citing works

Regulation of androgen receptor activity by tyrosine phosphorylation.

Guo, Z., Dai, B., Jiang, T., Xu, K., Xie, Y., Kim, O., Nesheiwat, I., Kong, X., Melamed, J., Handratta, V. D., et al. (2006) · Cancer Cell · doi:10.1016/j.ccr.2006.08.021 · Cited by 364 · see citing works

Beta-catenin affects androgen receptor transcriptional activity and ligand specificity.

Truica, C. I., Byers, S. W., & Gelmann, E. P. (2000) · PubMed · Cited by 349 · see citing works

Cell- and gene-specific regulation of primary target genes by the androgen receptorPreprint

Bolton, E. C., So, A. Y., Chaivorapol, C., Haqq, C. M., Li, H., & Yamamoto, K. R. (2007) · Genes & Development · doi:10.1101/gad.1564207 · Cited by 348 · see citing works

Molecular basis of androgen insensitivity

Brinkmann, A. O. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00466-x · Cited by 345 · see citing works

NSD1 is essential for early post‐implantation development and has a catalytically active SET domain

Rayasam, G. V., Wendling, O., Angrand, P., Mark, M. P., Niederreither, K., Song, L., Lerouge, T., Hager, G. L., Chambon, P., & Losson, R. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg288 · Cited by 343 · see citing works

Linking β-Catenin to Androgen-signaling Pathway

Yang, F., Li, X., Sharma, M., Sasaki, C. Y., Longo, D. L., Lim, B., & Sun, Z. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111962200 · Cited by 342 · see citing works

Determinants of caregiving experiences and mental health of partners of cancer patients

Nijboer, C., Triemstra, M., Tempelaar, R., Sanderman, R., & van den Bos, G. A. M. (1999) · Cancer · doi:10.1002/(sici)1097-0142(19990815)86:4 · Cited by 334 · see citing works

FHL2, a novel tissue‐specific coactivator of the androgen receptor

Müller, J. M., Isele, U., Metzger, E., Rempel, A., Moser, M., Pscherer, A., Breyer, T., Holubarsch, C., Buettner, R., & Schüle, R. (2000) · The EMBO Journal · doi:10.1093/emboj/19.3.359 · Cited by 326 · see citing works

Androgen deprivation therapy for prostate cancer: Current status and future prospects

Miyamoto, H., Messing, E. M., & Chang, C. (2004) · The Prostate · doi:10.1002/pros.20115 · Cited by 318 · see citing works

DJ-1 Positively Regulates the Androgen Receptor by Impairing the Binding of PIASxα to the Receptor

Takahashi, K., Taira, T., Niki, T., Seino, C., Iguchi‐Ariga, S. M. M., & Ariga, H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101730200 · Cited by 313 · see citing works

A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences.

Zhou, Z. X., Sar, M., Simental, J. A., Lane, M. V., & Wilson, E. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36806-0 · Cited by 312 · see citing works

Binding properties of androgen receptors. Evidence for identical receptors in rat testis, epididymis, and prostate.

Wilson, E. M., & French, F. S. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33103-4 · Cited by 312 · see citing works

Tip60 and Histone Deacetylase 1 Regulate Androgen Receptor Activity through Changes to the Acetylation Status of the Receptor

Gaughan, L., Logan, I. R., Cook, S., Neal, D. E., & Robson, C. N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203423200 · Cited by 310 · see citing works

Selective Phosphorylations of the SRC-3/AIB1 Coactivator Integrate Genomic Reponses to Multiple Cellular Signaling Pathways

Wu, R., Qin, J., Yi, P., Wong, J., Tsai, S. Y., Tsai, M., & O’Malley, B. W. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.08.019 · Cited by 297 · see citing works

Cloning and Characterization of Androgen Receptor Coactivator, ARA55, in Human Prostate

Fujimoto, N., Yeh, S., Kang, H., Inui, S., Chang, H., Mizokami, A., & Chang, C. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.12.8316 · Cited by 294 · see citing works

Caveolin-1 Maintains Activated Akt in Prostate CancerCells through Scaffolding Domain Binding Site Interactions with andInhibition of Serine/Threonine Protein Phosphatases PP1 andPP2A

Li, L., Ren, C. H., Tahir, S. A., Ren, C., & Thompson, T. C. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.24.9389-9404.2003 · Cited by 291 · see citing works

The Role of Hepatocyte Nuclear Factor-3α (Forkhead Box A1) and Androgen Receptor in Transcriptional Regulation of Prostatic Genes

Gao, N., Zhang, J., Rao, M. A., Case, T. C., Mirosevich, J., Wang, Y., Jin, R., Gupta, A., Rennie, P. S., & Matusik, R. J. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0020 · Cited by 279 · see citing works

Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation.

Mahajan, N. P., Liu, Y., Majumder, S., Warren, M. R., Parker, C. E., Mohler, J. L., Earp, H. S., & Whang, Y. E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700420104 · Cited by 274 · see citing works

Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth

Fu, M., Rao, M., Wang, C., Sakamaki, T., Wang, J., Vizio, D. D., Zhang, X., Albanese, C., Balk, S. P., Chang, C., et al. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.23.8563-8575.2003 · Cited by 274 · see citing works

Nuclear import of the human androgen receptor

Jenster, G. W., Trapman, J., & Brinkmann, A. O. (1993) · Biochemical Journal · doi:10.1042/bj2930761 · Cited by 273 · see citing works

Dissecting human adrenal androgen production

Rainey, W. E., Carr, B. R., Sasano, H., Suzuki, T., & Mason, J. I. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(02)00609-4 · Cited by 270 · see citing works

Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway.

Zhu, P., Baek, S. H., Bourk, E., Ohgi, K., Garcia-Bassets, I., Sanjo, H., Akira, S., Kotol, P., Glass, C., Rosenfeld, M., et al. (2006) · Cell · doi:10.1016/j.cell.2005.12.032 · Cited by 268 · see citing works

PDEF, a Novel Prostate Epithelium-specific Ets Transcription Factor, Interacts with the Androgen Receptor and Activates Prostate-specific Antigen Gene Expression

Oettgen, P., Finger, E., Sun, Z., Akbarali, Y., Thamrongsak, U., Boltax, J., Grall, F., Dube, A., Weiss, A., Brown, L., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.2.1216 · Cited by 268 · see citing works

The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription

Alen, P., Claessens, F., Verhoeven, G., Rombauts, W., & Peeters, B. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6085 · Cited by 268 · see citing works

From estrogen to androgen receptor: A new pathway for sex hormones in prostate

Yeh, S., Miyamoto, H., Shima, H., & Chang, C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.10.5527 · Cited by 267 · see citing works

The Function of TIF2/GRIP1 in Mouse Reproduction Is Distinct from Those of SRC-1 and p/CIP

Géhin, M., Mark, M. P., Dennefeld, C., Dierich, A., Gronemeyer, H., & Chambon, P. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.16.5923-5937.2002 · Cited by 262 · see citing works

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor

Massie, C. E., Adryan, B., Barbosa‐Morais, N. L., Lynch, A. G., Tran, M. G., Neal, D. E., & Mills, I. G. (2007) · The EMBO Reports · doi:10.1038/sj.embor.7401046 · Cited by 259 · see citing works

Interleukin 6 activates androgen receptor-mediated gene expression through a signal transducer and activator of transcription 3-dependent pathway in LNCaP prostate cancer cells.

Chen, T., Wang, L. H., & Farrar, W. L. (2000) · PubMed · Cited by 258 · see citing works

Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins

Ma, H., Hong, H., Huang, S.-M., Irvine, R. A., Webb, P., Kushner, P. J., Coetzee, G. A., & Stallcup, M. R. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6164 · Cited by 256 · see citing works

CREB-binding protein in androgen receptor-mediated signaling

Aarnisalo, P., Palvimo, J. J., & Jänne, O. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.5.2122 · Cited by 255 · see citing works

Tip60 Is a Nuclear Hormone Receptor Coactivator

Brady, M. E., Ozanne, D. M., Gaughan, L., Waite, I. S., Cook, S., Neal, D. E., & Robson, C. N. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17599 · Cited by 254 · see citing works

The multifunctional roles of the four-and-a-half-LIM only protein FHL2

Johannessen, M., Møller, S., Hansen, T. V. O., Moens, U. L., & Ghelue, M. V. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5438-z · Cited by 252 · see citing works

Caveolin-1 Interacts with Androgen Receptor

Lu, M. L., Schneider, M. C., Zheng, Y., Zhang, X., & Richie, J. P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006598200 · Cited by 239 · see citing works

Hormonal Control of Androgen Receptor Function through SIRT1

Fu, M., Liu, M., Sauve, A. A., Jiao, X., Zhang, X., Wu, X., Powell, M. J., Yang, T., Gu, W. J., Avantaggiati, M. L., et al. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00289-06 · Cited by 234 · see citing works

Testosterone and 5α-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene

Deslypère, J. P., Young, M., Wilson, J. D., & McPhaul, M. J. (1992) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(92)90004-p · Cited by 232 · see citing works

Cloning and Characterization of Human Prostate Coactivator ARA54, a Novel Protein That Associates with the Androgen Receptor

Kang, H., Yeh, S., Fujimoto, N., & Chang, C. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.13.8570 · Cited by 230 · see citing works

The Linkage of Kennedy's Neuron Disease to ARA24, the First Identified Androgen Receptor Polyglutamine Region-associated Coactivator

Hsiao, P., Lin, D., Nakao, R., & Chang, C. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.29.20229 · Cited by 221 · see citing works

PIAS1 and PIASxα Function as SUMO-E3 Ligases toward Androgen Receptor and Repress Androgen Receptor-dependent Transcription

Nishida, T., & Yasuda, H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206741200 · Cited by 217 · see citing works

Is the Achilles’ Heel for Prostate Cancer Therapy a Gain of Function in Androgen Receptor Signaling?

Litvinov, I. V., Marzo, A. M. D., & Isaacs, J. T. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-022038 · Cited by 215 · see citing works

Mutual Transcriptional Interference between RelA and Androgen Receptor

Palvimo, J. J., Reinikainen, P., Ikonen, T., Kallio, P. J., Moilanen, A., & Jänne, O. A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.39.24151 · Cited by 212 · see citing works

Physiological role for the cochaperone FKBP52 in androgen receptor signaling

Cheung-Flynn, J., Prapapanich, V., Cox, M. B., Riggs, D. L., Suarez-Quian, C., & Smith, D. F. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0071 · Cited by 212 · see citing works

Functional Interactions of the AF-2 Activation Domain Core Region of the Human Androgen Receptor with the Amino-Terminal Domain and with the Transcriptional Coactivator TIF2 (Transcriptional Intermediary Factor 2)

Berrevoets, C., Doesburg, P., Steketee, K., Trapman, J., & Brinkmann, A. O. (1998) · Molecular Endocrinology · doi:10.1210/mend.12.8.0153 · Cited by 212 · see citing works

Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription

Moilanen, A., Poukka, H., Karvonen, U., Häkli, M., Jänne, O. A., & Palvimo, J. J. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.9.5128 · Cited by 209 · see citing works

Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex*

Kang, Z., Pirskanen, A., Jänne, O., & Palvimo, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209074200 · Cited by 204 · see citing works

A role for cofactor–cofactor and cofactor–histone interactions in targeting p300, SWI/SNF and Mediator for transcription

Huang, Z.-Q., Li, J., Sachs, L. M., Cole, P. A., & Wong, J. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg219 · Cited by 203 · see citing works

Interactions between androgen and estrogen receptors and the effects on their transactivational properties

Panet-Raymond, V., Gottlieb, B., Beitel, L. K., Pinsky, L., & Trifiro, M. A. (2000) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00279-3 · Cited by 203 · see citing works

Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions

Loy, C. J., Sim, K. S., & Yong, E. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0736237100 · Cited by 202 · see citing works

Androgenic Induction of Prostate-specific Antigen Gene Is Repressed by Protein-Protein Interaction between the Androgen Receptor and AP-1/c-Jun in the Human Prostate Cancer Cell Line LNCaP

Sato, N., Sadar, M. D., Bruchovsky, N., Saatcioglu, F., Rennie, P. S., Sato, S., Lange, P. H., & Gleave, M. E. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.28.17485 · Cited by 202 · see citing works

The Androgen Receptor Represses Transforming Growth Factor-β Signaling through Interaction with Smad3

Chipuk, J. E., Cornelius, S. C., Pultz, N. J., Jorgensen, J. S., Bonham, M. J., Kim, S., & Danielpour, D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108855200 · Cited by 200 · see citing works

Androgen and Glucocorticoid Receptor Heterodimer Formation

Chen, S.-Y., Wang, J., Yu, G.-Q., Liu, W., & Pearce, D. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.22.14087 · Cited by 200 · see citing works

The Serine/Threonine Protein Kinase, p90 Ribosomal S6 Kinase, Is an Important Regulator of Prostate Cancer Cell Proliferation

Clark, D. E., Errington, T. M., Smith, J. A., Frierson, H. F., Weber, M. J., & Lannigan, D. A. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3151 · Cited by 200 · see citing works

DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex.

Niki, T., Takahashi-Niki, K., Taira, T., Iguchi‐Ariga, S. M. M., & Ariga, H. (2003) · PubMed · Cited by 197 · see citing works

BAG-1L Protein Enhances Androgen Receptor Function

Froesch, B. A., Takayama, S.-I. J., & Reed, J. C. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.19.11660 · Cited by 197 · see citing works

SMAD3 represses androgen receptor-mediated transcription.

Hayes, S. A., Zarnegar, M. A., Sharma, M., Yang, F., Peehl, D. M., ten Dijke, P., & Sun, Z. (2001) · PubMed · Cited by 192 · see citing works

Coregulator Recruitment and Histone Modifications in Transcriptional Regulation by the Androgen Receptor

Kang, Z., Jänne, O. A., & Palvimo, J. J. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0245 · Cited by 192 · see citing works

Androgen-Insensitivity Syndrome as a Possible Coactivator Disease

Adachi, M., Takayanagi, R., Tomura, A., Imasaki, K., Kato, S., Goto, K., Yanase, T., Ikuyama, S., & Nawata, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200009213431205 · Cited by 192 · see citing works

Cyclin D1 Binds the Androgen Receptor and Regulates Hormone-Dependent Signaling in a p300/CBP-Associated Factor (P/CAF)-Dependent Manner

Reutens, A. T., Fu, M., Wang, C., Albanese, C., McPhaul, M. J., Sun, Z., Balk, S. P., Jänne, O. A., Palvimo, J. J., & Pestell, R. G. (2001) · Molecular Endocrinology · doi:10.1210/mend.15.5.0641 · Cited by 189 · see citing works

The FXXLF Motif Mediates Androgen Receptor-specific Interactions with Coregulators

He, B., Minges, J. T., Lee, L. W., & Wilson, E. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111975200 · Cited by 188 · see citing works

Histone H3 Lysine 9 Methyltransferase G9a Is a Transcriptional Coactivator for Nuclear Receptors

Lee, D. Y., Northrop, J. P., Kuo, M., & Stallcup, M. R. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511093200 · Cited by 188 · see citing works

Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF.

McEwan, I., & Gustafsson, J.-Å. (1997) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.94.16.8485 · Cited by 186 · see citing works

D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability.

Knudsen, K. E., Cavenee, W. K., & Arden, K. C. (1999) · PubMed · Cited by 185 · see citing works

Sex hormones and liver cancer

Maria, N. D., Manno, M., & Villa, E. (2002) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(02)00096-5 · Cited by 179 · see citing works

ARIP3 (Androgen Receptor-Interacting Protein 3) and Other PIAS (Protein Inhibitor of Activated STAT) Proteins Differ in Their Ability to Modulate Steroid Receptor-Dependent Transcriptional Activation

Kotaja, N., Aittomäki, S., Silvennoinen, O., Palvimo, J. J., & Jänne, O. A. (2000) · Molecular Endocrinology · doi:10.1210/mend.14.12.0569 · Cited by 175 · see citing works

Ubc9 Interacts with the Androgen Receptor and Activates Receptor-dependent Transcription

Poukka, H., Aarnisalo, P., Karvonen, U., Palvimo, J. J., & Jänne, O. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.27.19441 · Cited by 174 · see citing works

Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation

Gaughan, L. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki141 · Cited by 174 · see citing works

The Androgen Receptor Can Promote β-Catenin Nuclear Translocation Independently of Adenomatous Polyposis Coli

Mulholland, D. J., Cheng, H., Reid, K. J., Rennie, P. S., & Nelson, C. C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200135200 · Cited by 173 · see citing works

SENP1 Enhances Androgen Receptor-Dependent Transcription through Desumoylation of Histone Deacetylase 1

Cheng, J., Wang, D., Wang, Z., & Yeh, E. T. H. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.13.6021-6028.2004 · Cited by 173 · see citing works

Compartmentalization of androgen receptor protein–protein interactions in living cells

van Royen, M. E., Cunha, S. M. P. R. M., Brink, M. C., Mattern, K. A., Nigg, A. L., Dubbink, H. J., Verschure, P. J., Trapman, J., & Houtsmuller, A. B. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200609178 · Cited by 170 · see citing works

Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells.

Yeh, S., Hu, Y.-C., Rahman, M., Lin, H.-K., Hsu, C.-L., Ting, H., Kang, H.-Y., & Chang, C. (2000) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.190353897 · Cited by 169 · see citing works

β-Catenin Binds to the Activation Function 2 Region of the Androgen Receptor and Modulates the Effects of the N-Terminal Domain and TIF2 on Ligand-Dependent Transcription

Song, L.-N., Herrell, R., Byers, S., Shah, S., Wilson, E. M., & Gelmann, E. P. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.5.1674-1687.2003 · Cited by 169 · see citing works

Dependence of Selective Gene Activation on the Androgen Receptor NH2- and COOH-terminal Interaction

He, B., Lee, L. W., Minges, J. T., & Wilson, E. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202809200 · Cited by 168 · see citing works

Dynamic nucleosomes and gene transcription

Mellor, J. (2006) · Trends in Genetics · doi:10.1016/j.tig.2006.03.008 · Cited by 168 · see citing works

Androgens Modulate Expression of Transcription Intermediary Factor 2, an Androgen Receptor Coactivator whose Expression Level Correlates with Early Biochemical Recurrence in Prostate Cancer

Agoulnik, I. U., Vaid, A., Nakka, M., Alvarado, M., Bingman, W. E., Erdem, H., Frolov, A., Smith, C. S., Ayala, G. E., Ittmann, M., et al. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-1023 · Cited by 168 · see citing works

Breast cancer susceptibility gene 1 (BRCAI) is a coactivator of the androgen receptor.

Park, J. M., Irvine, R. A., Buchanan, G., Koh, S. S., Park, J. M., Tilley, W. D., Stallcup, M. R., Press, M. F., & Coetzee, G. A. (2000) · PubMed · Cited by 166 · see citing works

Liganded Androgen Receptor Interaction with β-Catenin

Pawlowski, J. E., Ertel, J. R., Allen, M. P., Xu, M., Butler, C., Wilson, E. M., & Wierman, M. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200545200 · Cited by 166 · see citing works

Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells

Gross, M. E., Liu, B., Tan, J.-A., French, F. S., Carey, M., & Shuai, K. (2001) · Oncogene · doi:10.1038/sj.onc.1204489 · Cited by 165 · see citing works

Androgen Receptor Nuclear Translocation Is Facilitated by the f-Actin Cross-Linking Protein Filamin

Ozanne, D. M., Brady, M. E., Cook, S., Gaughan, L., Neal, D. E., & Robson, C. N. (2000) · Molecular Endocrinology · doi:10.1210/mend.14.10.0541 · Cited by 162 · see citing works

Proteasome Activity Is Required for Androgen Receptor Transcriptional Activity via Regulation of Androgen Receptor Nuclear Translocation and Interaction with Coregulators in Prostate Cancer Cells*

Lin, H.-K., Altuwaijri, S., Lin, W.-J., Kan, P.-Y., Collins, L., & Chang, C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204751200 · Cited by 160 · see citing works

AKT-Independent Protection of Prostate Cancer Cells from Apoptosis Mediated through Complex Formation between the Androgen Receptor and FKHR

Li, P., Lee, H., Guo, S., Unterman, T. G., Jenster, G. W., & Bai, W. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.23.1.104-118.2003 · Cited by 160 · see citing works

Androgens in women

Davison, S. L., & Davis, S. R. (2003) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(03)00204-8 · Cited by 159 · see citing works

Androgen Receptor Specifically Interacts with a Novel p21-activated Kinase, PAK6

Yang, F., Li, X., Sharma, M., Zarnegar, M. A., Lim, B., & Sun, Z. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010311200 · Cited by 157 · see citing works

Androgen-induced recruitment of RNA polymerase II to a nuclear receptor–p160 coactivator complex

Louie, M. C., Yang, H. Q., Ma, A., Xu, W., Zou, J. X., Kung, H.-J., & Chen, H.-W. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0437824100 · Cited by 157 · see citing works

Essential role for co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology

Yong, W., Yang, Z., Periyasamy, S., Chen, H., Yucel, S., Li, W., Lin, L. Y., Wolf, I. M., Cohn, M. J., Baskin, L. S., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m609360200 · Cited by 156 · see citing works

The hinge region regulates DNA binding, nuclear translocation, and transactivation of the androgen receptor

Haelens, A., Tanner, T., Denayer, S., Callewaert, L., & Claessens, F. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-1701 · Cited by 153 · see citing works

From transforming growth factor-β signaling to androgen action: Identification of Smad3 as an androgen receptor coregulator in prostate cancer cells

Kang, H., Lin, H., Hu, Y., Yeh, S., Huang, K., & Chang, C. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061305498 · Cited by 152 · see citing works

Mouse Zac1, a Transcriptional Coactivator and Repressor for Nuclear Receptors

Huang, S., & Stallcup, M. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.5.1855-1867.2000 · Cited by 148 · see citing works

HOXB13 Induces Growth Suppression of Prostate Cancer Cells as a Repressor of Hormone-Activated Androgen Receptor Signaling

Jung, C., Kim, R.-S., Zhang, H., Lee, S.-J., & Jeng, M. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-1330 · Cited by 147 · see citing works

SUMO: regulating the regulator.

Bossis, G., & Melchior, F. (2006) · Cell Division · doi:10.1186/1747-1028-1-13 · Cited by 147 · see citing works

Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability

Majumder, S., Liu, Y., Ford, O. H., Mohler, J. L., & Whang, Y. E. (2006) · The Prostate · doi:10.1002/pros.20438 · Cited by 146 · see citing works

Actin in transcription and transcription regulation

Miralles, F., & Visa, N. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.04.009 · Cited by 145 · see citing works

Inhibition of Androgen Receptor (AR) Function by the Reproductive Orphan Nuclear Receptor DAX-1

Holter, E., Kotaja, N., Mäkelä, S., Strauss, L., Kietz, S., Jänne, O. A., Gustafsson, J.-Α., Palvimo, J. J., & Treuter, E. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.3.0804 · Cited by 144 · see citing works

Cyclin D1: Mechanism and Consequence of Androgen Receptor Co-repressor Activity

Petre, C. E., Wetherill, Y. B., Danielsen, M., & Knudsen, K. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106399200 · Cited by 144 · see citing works

Isolation and Characterization of ARA160 as the First Androgen Receptor N-terminal-associated Coactivator in Human Prostate Cells

Hsiao, P., & Chang, C. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.32.22373 · Cited by 142 · see citing works

Endocytic adaptors: recruiters, coordinators and regulators.

Maldonado-Báez, L., & Wendland, B. (2006) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.08.001 · Cited by 141 · see citing works

Repressors of Androgen and Progesterone Receptor Action

Agoulnik, I. U., Krause, W. C., Bingman, W. E., Rahman, H., Amrikachi, M., Ayala, G. E., & Weigel, N. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305153200 · Cited by 141 · see citing works

SOX9 Is Expressed in Normal Prostate Basal Cells and Regulates Androgen Receptor Expression in Prostate Cancer Cells

Wang, H., McKnight, N. C., Zhang, T., Lu, M. L., Balk, S. P., & Yuan, X. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-1672 · Cited by 141 · see citing works

FOXO1A Is a Candidate for the 13q14 Tumor Suppressor Gene Inhibiting Androgen Receptor Signaling in Prostate Cancer

Dong, X.-Y., Chen, C., Sun, X., Guo, P., Vessella, R. L., Wang, R.-X., Chung, L. W. K., Zhou, W., & Dong, J. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0411 · Cited by 138 · see citing works

An Androgen Receptor NH2-terminal Conserved Motif Interacts with the COOH Terminus of the Hsp70-interacting Protein (CHIP)

He, B., Bai, S., Hnat, A. T., Kalman, R. I., Minges, J. T., Patterson, C., & Wilson, E. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403117200 · Cited by 137 · see citing works

Androgen Receptor Interacts with a Novel MYST Protein, HBO1

Sharma, M., Zarnegar, M. A., Li, X., Lim, B., & Sun, Z. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004838200 · Cited by 137 · see citing works

Hey1, a Mediator of Notch Signaling, Is an Androgen Receptor Corepressor

Belandia, B., Powell, S. M., Garcia-Pedrero, J. M., Walker, M. M., Bevan, C. L., & Parker, M. G. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.4.1425-1436.2005 · Cited by 137 · see citing works

Molecular mechanisms of steroid hormone action

White, R., & Parker, M. G. (1998) · Endocrine Related Cancer · doi:10.1677/erc.0.0050001 · Cited by 137 · see citing works

Androgen Receptor Interacts with the Positive Elongation Factor P-TEFb and Enhances the Efficiency of Transcriptional Elongation

Lee, D. K., Duan, H. O., & Chang, C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m002285200 · Cited by 136 · see citing works

Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level

Chiu, C.-M., Yeh, S., Chen, P., Kuo, T.-J., Chang, C.-J., Chen, P., Yang, W., & Chen, D. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609498104 · Cited by 135 · see citing works

Retinoblastoma, a Tumor Suppressor, Is a Coactivator for the Androgen Receptor in Human Prostate Cancer DU145 Cells

Yeh, S., Miyamoto, H., Nishimura, K., Kang, H., Ludlow, J. W., Hsiao, P., Wang, C., Su, C.-Y., & Chang, C. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8974 · Cited by 135 · see citing works

AR and ER Interaction with a p21-Activated Kinase (PAK6)

Lee, S. R., Ramos, S. M., Ko, A. H., Masiello, D., Swanson, K. D., Lu, M. L., & Balk, S. P. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.1.0753 · Cited by 134 · see citing works

Melanoma Antigen Gene Protein MAGE-11 Regulates Androgen Receptor Function by Modulating the Interdomain Interaction

Bai, S., He, B., & Wilson, E. M. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.4.1238-1257.2005 · Cited by 133 · see citing works

Expression and role of Foxa proteins in prostate cancer

Mirosevich, J., Gao, N., Gupta, A., Shappell, S. B., Jove, R., & Matusik, R. J. (2005) · The Prostate · doi:10.1002/pros.20299 · Cited by 132 · see citing works

BAF57 Governs Androgen Receptor Action and Androgen-Dependent Proliferation through SWI/SNF

Link, K. A., Burd, C. J., Williams, E., Marshall, T. W., Rosson, G. B., Henry, E. C., Weissman, B. E., & Knudsen, K. E. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2200-2215.2005 · Cited by 131 · see citing works

hZimp10 is an androgen receptor co‐activator and forms a complex with SUMO‐1 at replication foci

Sharma, M., Li, X., Wang, Y., Zarnegar, M. A., Huang, C., Palvimo, J. J., Lim, B., & Sun, Z. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg585 · Cited by 129 · see citing works

Regulation of Androgen Receptor Signaling by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10) Tumor Suppressor through Distinct Mechanisms in Prostate Cancer Cells

Lin, H., Hu, Y., Lee, D., & Chang, C. (2004) · Molecular Endocrinology · doi:10.1210/me.2004-0117 · Cited by 129 · see citing works

Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation

Burd, C. J., Petre, C. E., Morey, L. M., Wang, Y., Revelo, M. P., Haiman, C. A., Lu, S., Fenoglio‐Preiser, C. M., Li, J., Knudsen, E. S., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506281103 · Cited by 125 · see citing works

Largest Subunits of the Human SWI/SNF Chromatin-remodeling Complex Promote Transcriptional Activation by Steroid Hormone Receptors

Inoue, H., Furukawa, T., Giannakopoulos, S., Zhou, S., King, D., & Tanese, N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205961200 · Cited by 122 · see citing works

Differential Requirement of SWI/SNF for Androgen Receptor Activity

Marshall, T. W., Link, K. A., Petre, C. E., & Knudsen, K. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304582200 · Cited by 121 · see citing works

Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids (Review)

Cheng, Z.-J. J., Singh, R. D., Marks, D. L., & Pagano, R. E. (2006) · Molecular Membrane Biology · doi:10.1080/09687860500460041 · Cited by 121 · see citing works

Interaction of the Putative Androgen Receptor-Specific Coactivator ARA70/ELE1 with Multiple Steroid Receptors and Identification of an Internally Deleted ELE1 Isoform

Alen, P., Claessens, F., Schoenmakers, E., Swinnen, J. V., Verhoeven, G., Rombauts, W., & Peeters, B. (1999) · Molecular Endocrinology · doi:10.1210/mend.13.1.0214 · Cited by 120 · see citing works

Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor.

Kraus, S., Gioeli, D., Vomastek, T., Gordon, V., & Weber, M. J. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0596 · Cited by 118 · see citing works

Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer

Ngan, E., Hashimoto, Y., Ma, Z.-Q., Tsai, M., & Tsai, S. Y. (2003) · Oncogene · doi:10.1038/sj.onc.1206121 · Cited by 118 · see citing works

From Androgen Receptor to the General Transcription Factor TFIIH

Lee, D. K., Duan, H. O., & Chang, C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9308 · Cited by 117 · see citing works

p23, a simple protein with complex activities

Felts, S. J., & Toft, D. O. (2003) · Cell Stress and Chaperones · doi:10.1379/1466-1268(2003)008 · Cited by 116 · see citing works

Androgen receptor corepressors: An overview

Wang, L., Hsu, C., & Chang, C. (2004) · The Prostate · doi:10.1002/pros.20170 · Cited by 115 · see citing works

The RING finger protein SNURF modulates nuclear trafficking of the androgen receptor

Poukka, H., Karvonen, U., Yoshikawa, N., Tanaka, H., Palvimo, J. J., & Jänne, O. A. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.17.2991 · Cited by 115 · see citing works

Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.

Nishimura, K., Ting, H., Harada, Y., Tokizane, T., Nonomura, N., Kang, H., Chang, H., Yeh, S., Miyamoto, H., Shin, M., et al. (2003) · PubMed · Cited by 115 · see citing works

Keeping transcriptional activators under control.

Kodadek, T., Sikder, D., & Nalley, K. (2006) · Cell · doi:10.1016/j.cell.2006.10.002 · Cited by 114 · see citing works

A role for GATA transcription factors in the androgen regulation of the prostate-specific antigen gene enhancer

Perez‐Stable, C., Pozas, A. D. L., & Roos, B. A. (2000) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00300-2 · Cited by 112 · see citing works

Activation of Androgen Receptor Function by a Novel Nuclear Protein Kinase

Moilanen, A., Karvonen, U., Poukka, H., Jänne, O. A., & Palvimo, J. J. (1998) · Molecular Biology of the Cell · doi:10.1091/mbc.9.9.2527 · Cited by 111 · see citing works

Ligand-independent Androgen Receptor Activity Is Activation Function-2-independent and Resistant to Antiandrogens in Androgen Refractory Prostate Cancer Cells

Dehm, S. M., & Tindall, D. J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m605002200 · Cited by 111 · see citing works

Antagonism between PTEN/MMAC1/TEP-1 and Androgen Receptor in Growth and Apoptosis of Prostatic Cancer Cells

Li, P., Nicosia, S. V., & Bai, W. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010226200 · Cited by 110 · see citing works

A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer

Metzger, E., Müller, J. M., Ferrari, S., Buettner, R., & Schüle, R. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg023 · Cited by 110 · see citing works

c-Jun Can Mediate Androgen Receptor-induced Transactivation

Bubulya, A., Wise, S., Shen, X.-Q., Burmeister, L. A., & Shemshedini, L. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.40.24583 · Cited by 110 · see citing works

The androgen receptor co‐activator CBP is up‐regulated following androgen withdrawal and is highly expressed in advanced prostate cancer

Comuzzi, B., Nemes, C., Schmidt, S. U., Jasarevic, Z., Lodde, M., Pycha, A., Bartsch, G. H., Offner, F. A., Čulig, Z., & Hobisch, A. (2004) · The Journal of Pathology · doi:10.1002/path.1609 · Cited by 109 · see citing works

Differential Modulation of Androgen Receptor-mediated Transactivation by Smad3 and Tumor Suppressor Smad4

Kang, H., Huang, K., Chang, S., Ma, W., Lin, W., & Chang, C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205603200 · Cited by 109 · see citing works

Cyclin E as a Coactivator of the Androgen Receptor

Yamamoto, A., Hashimoto, Y., Kohri, K., Ogata, E., Kato, S., Ikeda, K., & Nakanishi, M. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.4.873 · Cited by 108 · see citing works

SRY Interacts with and Negatively Regulates Androgen Receptor Transcriptional Activity

Yuan, X., Lu, M. L., Li, T., & Balk, S. P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m108404200 · Cited by 108 · see citing works

Induced α-Helix Structure in AF1 of the Androgen Receptor upon Binding Transcription Factor TFIIF

Kumar, R., Betney, R., Li, J., Thompson, E. B., & McEwan, I. J. (2004) · Biochemistry · doi:10.1021/bi035934p · Cited by 107 · see citing works

Androgen Deprivation Increases p300 Expression in Prostate Cancer Cells

Heemers, H. V., Sebo, T. J., Debes, J. D., Regan, K. M., Raclaw, K. A., Murphy, L. M., Hobisch, A., Čulig, Z., & Tindall, D. J. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-2836 · Cited by 107 · see citing works

C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation

Cardozo, C. P., Michaud, C., Ost, M. C., Fliss, A., Yang, E., Patterson, C., Hall, S. J., & Caplan, A. J. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(02)00680-x · Cited by 106 · see citing works

A Coregulatory Role for the TRAP-Mediator Complex in Androgen Receptor-mediated Gene Expression

Wang, Q., Sharma, D., Ren, Y., & Fondell, J. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206061200 · Cited by 104 · see citing works

Inhibition of Androgen Receptor-Mediated Transcription by Amino-Terminal Enhancer of split

Yu, X., Li, P., Roeder, R. G., & Wang, Z. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.14.4614-4625.2001 · Cited by 104 · see citing works

p53 Represses Androgen-induced Transactivation of Prostate-specific Antigen by Disrupting hAR Amino- to Carboxyl-terminal Interaction

Shenk, J. L., Fisher, C. J., Chen, S., Zhou, X., Tillman, K. C., & Shemshedini, L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103652200 · Cited by 103 · see citing works

Molecular chaperones throughout the life cycle of the androgen receptor

Prescott, J., & Coetzee, G. A. (2005) · Cancer Letters · doi:10.1016/j.canlet.2004.12.037 · Cited by 103 · see citing works

Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells

Lim, J. T. E., MANSUKHANI, M. M., & Weinstein, I. B. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501203102 · Cited by 102 · see citing works

Involvement of transcription factor Sp1 in quercetin-mediated inhibitory effect on the androgen receptor in human prostate cancer cells

Yuan, H. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi021 · Cited by 102 · see citing works

RanBPM, a Nuclear Protein That Interacts with and Regulates Transcriptional Activity of Androgen Receptor and Glucocorticoid Receptor

Rao, M. A., Cheng, H., Quayle, A. N., Nishitani, H., Nelson, C. C., & Rennie, P. S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209741200 · Cited by 102 · see citing works

Supervillin associates with androgen receptor and modulates its transcriptional activity

Ting, H., Yeh, S., Nishimura, K., & Chang, C. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022469899 · Cited by 100 · see citing works

Androgen mediated regulation and functional implications of FKBP51 expression in prostate cancer

FEBBO, P. G., LOWENBERG, M., THORNER, A. R., BROWN, M., LODA, M., & GOLUB, T. R. (2005) · Journal of Urology · doi:10.1097/01.ju.0000155845.44729.ba · Cited by 99 · see citing works

Tip60 Is a Co-activator Specific for Class I Nuclear Hormone Receptors

Gaughan, L., Brady, M. E., Cook, S., Neal, D. E., & Robson, C. N. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103710200 · Cited by 98 · see citing works

Functional Domain and Motif Analyses of Androgen Receptor Coregulator ARA70 and Its Differential Expression in Prostate Cancer

Hu, Y., Yeh, S., Yeh, S.-D., Sampson, E. R., Huang, J., Li, P., Hsu, C.-L., Ting, H., Lin, H., Wang, L., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401781200 · Cited by 98 · see citing works

N‐Terminally extended human ubiquitin‐conjugating enzymes (E2s) mediate the ubiquitination of RING‐finger proteins, ARA54 and RNF8

Ito, K., Adachi, S., Iwakami, R., Yasuda, H., Muto, Y., Seki, N., & Okano, Y. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2001.02169.x · Cited by 97 · see citing works

TSG101 Interacts with Apoptosis-antagonizing Transcription Factor and Enhances Androgen Receptor-mediated Transcription by Promoting Its Monoubiquitination

Burgdorf, S., Leister, P., & Scheidtmann, K. H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313703200 · Cited by 97 · see citing works

The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells

Zhang, Y., Wang, X. W., Jelovac, D., Nakanishi, T., Yu, M.-H., Akinmade, D., Goloubeva, O. G., Ross, D. D., Brodie, A. M. H., & Hamburger, A. W. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503829102 · Cited by 97 · see citing works

Protein Inhibitor of Activated STAT-1 (Signal Transducer and Activator of Transcription-1) Is a Nuclear Receptor Coregulator Expressed in Human Testis

Tan, J.-A., Hall, S. H., Hamil, K. G., Grossman, G., Petrusz, P., Liao, J., Shuai, K., & French, F. S. (2000) · Molecular Endocrinology · doi:10.1210/mend.14.1.0408 · Cited by 96 · see citing works

DJ-1 Binds Androgen Receptor Directly and Mediates Its Activity in Hormonally Treated Prostate Cancer Cells

Tillman, J., Yuan, J., Gu, G., Fazli, L., Ghosh, R., Flynt, A. S., Gleave, M. E., Rennie, P. S., & Kasper, S. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-4556 · Cited by 95 · see citing works

The Molecular Taxonomy of Primary Prostate Cancer

Abeshouse, A. A., Ahn, J., Akbani, R., Ally, A., Amin, S. B., Andry, C., Annala, M., Aprikian, A. G., Armenia, J., Arora, A., et al. (2015) · Cell · doi:10.1016/j.cell.2015.10.025 · Cited by 3,082 · see citing works

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

Yu, J., Yu, J., Mani, R.-S., Cao, Q., Brenner, C. J., Cao, X., Wang, X., Wu, L., Li, J., Hu, M., et al. (2010) · Cancer Cell · doi:10.1016/j.ccr.2010.03.018 · Cited by 850 · see citing works

Estrogens and androgens in skeletal physiology and pathophysiology

Almeida, M., Laurent, M. R., Dubois, V., Claessens, F., O'Brien, C. A., Bouillon, R., Vanderschueren, D., & Manolagas, S. C. (2017) · Physiological Reviews · doi:10.1152/physrev.00033.2015 · Cited by 860 · see citing works

Androgen Receptor Structure, Function and Biology: From Bench to Bedside.

(2016) · Europe PMC (PubMed Central) · Cited by 623 · see citing works

A Clinically Relevant Androgen Receptor Mutation Confers Resistance to Second-Generation Antiandrogens Enzalutamide and ARN-509

Joseph, J. D., Lu, N., Qian, J., Sensintaffar, J., Shao, G., Brigham, D., Moon, M., Maneval, E. C., Chen, I., Darimont, B. D., et al. (2013) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-0226 · Cited by 578 · see citing works

Androgen insensitivity syndrome

Hughes, I. A., Davies, J. D., Bunch, T., Pasterski, V., Mastroyannopoulou, K., & MacDougall, J. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60071-3 · Cited by 556 · see citing works

Androgen receptor signaling in prostate cancer development and progression

Tindall, D. J., & Lonergan, P. E. (2011) · Journal of Carcinogenesis · doi:10.4103/1477-3163.83937 · Cited by 544 · see citing works

Mechanisms of resistance in castration-resistant prostate cancer (CRPC).

Chandrasekar, T., Yang, J. C., Gao, A. C., & Evans, C. P. (2015) · PubMed Central · doi:10.3978/j.issn.2223-4683.2015.05.02 · Cited by 531 · see citing works

Androgen receptors in hormone-dependent and castration-resistant prostate cancer

Shafi, A. A., Yen, A. E., & Weigel, N. L. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.07.003 · Cited by 422 · see citing works

Androgen Signaling in Prostate CancerPreprint

Dai, C. S., Heemers, H. V., & Sharifi, N. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a030452 · Cited by 412 · see citing works

Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

Sahu, B., Laakso, M., Ovaska, K., Mirtti, T. K., Lundin, J. E., Rannikko, A. S., Sankila, A., Turunen, J.-P., Lundin, M., Konsti, J., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.328 · Cited by 386 · see citing works

Alternatively spliced androgen receptor variants

Dehm, S. M., & Tindall, D. J. (2011) · Endocrine Related Cancer · doi:10.1530/erc-11-0141 · Cited by 380 · see citing works

An androgen receptor N-terminal domain antagonist for treating prostate cancer

Myung, J., Banuelos, C. A., Fernandez, J. G., Mawji, N. R., Wang, J., Tien, A. H., Yang, Y. C., Tavakoli, I., Haile, S., Watt, K., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci66398 · Cited by 307 · see citing works

Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications

Ostrovidov, S., Hosseini, V., Ahadian, S., Fujie, T., Parthiban, S. P., Ramalingam, M., Bae, H., Kaji, H., & Khademhosseini, A. (2014) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2013.0534 · Cited by 302 · see citing works

Molecular cell biology of androgen receptor signalling

Bennett, N. C., Gardiner, R. A., Hooper, J. D., Johnson, D. W., & Gobe, G. C. (2010) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2009.11.013 · Cited by 292 · see citing works

Association of a novel long non‐coding RNA in 8q24 with prostate cancer susceptibility

Chung, S., Nakagawa, H., Uemura, M., Piao, L., Ashikawa, K., Hosono, N., Takata, R., Akamatsu, S., Kawaguchi, T., Morizono, T., et al. (2010) · Cancer Science · doi:10.1111/j.1349-7006.2010.01737.x · Cited by 286 · see citing works

Nuclear Receptors and Their Selective Pharmacologic Modulators

Burris, T. P., Solt, L. A., Wang, Y., Crumbley, C., Banerjee, S., Griffett, K., Lundåsen, T., Hughes, T., & Kojetin, D. J. (2013) · Pharmacological Reviews · doi:10.1124/pr.112.006833 · Cited by 285 · see citing works

The Androgen Receptor in Health and Disease

Μatsumoto, T., Sakari, M., Okada, M., Yokoyama, A., Takahashi, S., Kouzmenko, A., & Kato, S. (2012) · Annual Review of Physiology · doi:10.1146/annurev-physiol-030212-183656 · Cited by 268 · see citing works

Kallikreins on Steroids: Structure, Function, and Hormonal Regulation of Prostate-Specific Antigen and the Extended Kallikrein Locus

Lawrence, M. G., Lai, J., & Clements, J. A. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0034 · Cited by 266 · see citing works

Peptidomimetic targeting of critical androgen receptor–coregulator interactions in prostate cancer

Ravindranathan, P., Lee, T.-K., Yang, L., Centenera, M. M., Butler, L. M., Tilley, W. D., Hsieh, J., Ahn, J., & Raj, G. V. (2013) · Nature Communications · doi:10.1038/ncomms2912 · Cited by 255 · see citing works

ETV1, 4 and 5: An oncogenic subfamily of ETS transcription factors

Oh, S., Shin, S., & Janknecht, R. (2012) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2012.02.002 · Cited by 248 · see citing works

Androgen receptor and androgen-dependent gene expression in lung

Mikkonen, L., Pihlajamaa, P., Sahu, B., Zhang, F., & Jänne, O. A. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.12.022 · Cited by 243 · see citing works

Molecular Mechanisms and Signaling Pathways Involved in Sertoli Cell Proliferation

Meroni, S. B., Galardo, M. N., Rindone, G. M., Gorga, A., Riera, M. F., & Cigorraga, S. B. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00224 · Cited by 229 · see citing works

MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma

Boll, K., Reiche, K., Kasack, K., Mörbt, N., Kretzschmar, A. K., Tomm, J. M., Verhaegh, G. W. C. T., Schalken, J. A., von Bergen�, M., Horn, F., et al. (2012) · Oncogene · doi:10.1038/onc.2012.55 · Cited by 214 · see citing works

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

Chang, C., Lee, S. O., Yeh, S., & Chang, T. M. (2013) · Oncogene · doi:10.1038/onc.2013.274 · Cited by 214 · see citing works

Role of androgen receptor and associated lysine‐demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer

KAUFFMAN, E. C., Robinson, B. D., Downes, M., Powell, L. G., Lee, M. M., Scherr, D. S., Gudas, L. J., & Mongan, N. P. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20758 · Cited by 211 · see citing works

The role of androgen and androgen receptor in skin-related disorders

Lai, J.-J., Chang, P., Lai, K.-P., Chen, L., & Chang, C. (2012) · Archives of Dermatological Research · doi:10.1007/s00403-012-1265-x · Cited by 207 · see citing works

Androgen insensitivity syndrome

Mongan, N. P., Tadokoro‐Cuccaro, R., Bunch, T., & Hughes, I. A. (2015) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2015.04.005 · Cited by 205 · see citing works

AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression

Li, Y., Hwang, T. H., Oseth, L., Hauge, A., Vessella, R. L., Schmechel, S. C., Hirsch, B. A., Beckman, K. B., Silverstein, K. A. T., & Dehm, S. M. (2012) · Oncogene · doi:10.1038/onc.2011.637 · Cited by 197 · see citing works

The RNA Helicase p68 Is a Novel Androgen Receptor Coactivator Involved in Splicing and Is Overexpressed in Prostate Cancer

Clark, E. L., Coulson, A., Dalgliesh, C., Rajan, P., Nicol, S. M., Fleming, S., Heer, R., Gaughan, L., Leung, H. Y., Elliott, D. J., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-0932 · Cited by 201 · see citing works

Basics of androgen synthesis and action

Elzenaty, R. N., du Toit, T., & Flück, C. E. (2022) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2022.101665 · Cited by 204 · see citing works

Intragenic Rearrangement and Altered RNA Splicing of the Androgen Receptor in a Cell-Based Model of Prostate Cancer Progression

Li, Y., Alsagabi, M., Fan, D., Bova, G. S., Tewfik, A. H., & Dehm, S. M. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-1998 · Cited by 200 · see citing works

Understanding and overcoming the mechanisms of primary and acquired resistance to abiraterone and enzalutamide in castration resistant prostate cancer

Buttigliero, C., Tucci, M., Bertaglia, V., Vignani, F., Bironzo, P., Maïo, M. D., & Scagliotti, G. V. (2015) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2015.08.002 · Cited by 197 · see citing works

Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions

Dubois, V., Laurent, M., Boonen, S., Vanderschueren, D., & Claessens, F. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0883-3 · Cited by 197 · see citing works

Benzimidazole Scaffold as Anticancer Agent: Synthetic Approaches and Structure–Activity Relationship

Shrivastava, N., Naim, M. J., Alam, M. J., Nawaz, F., Ahmed, S., & Alam, O. (2017) · Archiv der Pharmazie · doi:10.1002/ardp.201700040 · Cited by 192 · see citing works

The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor

Cui, Z., Ren, S., Lu, J., Wang, F., Xu, W., Sun, Y., Wei, M., Chen, J., Gao, X., Xu, C., et al. (2012) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2011.11.030 · Cited by 187 · see citing works

Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program

Jin, H., Zhao, J. C., Wu, L., Kim, J., & Yu, J. (2014) · Nature Communications · doi:10.1038/ncomms4972 · Cited by 185 · see citing works

Integration of Regulatory Networks by NKX3-1 Promotes Androgen-Dependent Prostate Cancer Survival

Tan, P. Y., Chang, C. W., Chng, K. R., Wansa, K. D. S. A., Sung, W.-K. K., & Cheung, E. C. W. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05958-11 · Cited by 180 · see citing works

Genetic evidence of gender difference in autism spectrum disorder supports the female-protective effect

Zhang, Y., Li, N., Li, C., Zhang, Z., Teng, H., Wang, Y., Zhao, T., Shi, L., Zhang, K., Xia, K., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0699-8 · Cited by 177 · see citing works

The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination

Hussain, R., Ghoumari, A. M., Bielecki, B., Steibel, J., Boehm, N., Lière, P., Macklin, W. B., Kumar, N., Habert, R., Mhaouty‐Kodja, S., et al. (2013) · Brain · doi:10.1093/brain/aws284 · Cited by 176 · see citing works

Epigenetic Repression of miR-31 Disrupts Androgen Receptor Homeostasis and Contributes to Prostate Cancer Progression

Lin, P., Chiu, Y., Banerjee, S., Park, K., Mosquera, J. M., Γιαννοπούλου, Ε., Alves, P., Tewari, A. K., Gerstein, M., Beltran, H., et al. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-2968 · Cited by 168 · see citing works

Androgen receptor signaling and mutations in prostate cancer

Koochekpour, S. (2010) · Asian Journal of Andrology · doi:10.1038/aja.2010.89 · Cited by 167 · see citing works

Ontogeny of the androgen receptor expression in the fetal and postnatal testis: Its relevance on Sertoli cell maturation and the onset of adult spermatogenesis

Rey, R. A., Musse, M. P., Venara, M. C., & Chemes, H. (2009) · Microscopy Research and Technique · doi:10.1002/jemt.20754 · Cited by 167 · see citing works

Targeting the Androgen Signaling Axis in Prostate Cancer

Dai, C. S., Dehm, S. M., & Sharifi, N. (2023) · Journal of Clinical Oncology · doi:10.1200/jco.23.00433 · Cited by 172 · see citing works

Beyond acne: Current aspects of sebaceous gland biology and function

Zouboulis, C. C., Picardo, M., Ju, Q., Kurokawa, I., Törőcsik, D., Bíró, T., & Schneider, M. R. (2016) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-016-9389-5 · Cited by 174 · see citing works

Androgen Receptor (AR) Physiological Roles in Male and Female Reproductive Systems: Lessons Learned from AR-Knockout Mice Lacking AR in Selective Cells1

Chang, C., Lee, S. O., Wang, R.-S., Yeh, S., & Chang, T. (2013) · Biology of Reproduction · doi:10.1095/biolreprod.113.109132 · Cited by 163 · see citing works

Potential role of F ox O 1 and m TORC 1 in the pathogenesis of W estern diet‐induced acne

Melnik, B. C., & Zouboulis, C. C. (2013) · Experimental Dermatology · doi:10.1111/exd.12142 · Cited by 163 · see citing works

Mechanisms of crosstalk between endocrine systems: Regulation of sex steroid hormone synthesis and action by thyroid hormones

Duarte‐Guterman, P., Navarro‐Martín, L., & Trudeau, V. L. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.03.015 · Cited by 163 · see citing works

Androgen-Induced Coactivator ANCCA Mediates Specific Androgen Receptor Signaling in Prostate Cancer

Zou, J. X., Guo, L., Revenko, A. S., Tepper, C. G., Gemo, A. T., Kung, H.-J., & Chen, H.-W. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3440 · Cited by 161 · see citing works

Mechanisms of Therapeutic Resistance in Prostate Cancer

Nakazawa, M., Paller, C. J., & Kyprianou, N. (2017) · Current Oncology Reports · doi:10.1007/s11912-017-0568-7 · Cited by 152 · see citing works

Nuclear actin and actin‐binding proteins in the regulation of transcription and gene expression

Zheng, B., Han, M., Bernier, M., & Wen, J. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.06986.x · Cited by 152 · see citing works

Molecular pharmacology of the mineralocorticoid receptor: Prospects for novel therapeutics

Kolkhof, P., & Borden, S. A. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.06.025 · Cited by 152 · see citing works

Influence of Androgens on Immunity to Self and Foreign: Effects on Immunity and Cancer

Ben-Batalla, I., Vargas-Delgado, M. E., von Amsberg, G., Janning, M., & Loges, S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01184 · Cited by 149 · see citing works

Minireview: Alternative Activation Pathways for the Androgen Receptor in Prostate Cancer

Lamont, K. R., & Tindall, D. J. (2011) · Molecular Endocrinology · doi:10.1210/me.2010-0469 · Cited by 150 · see citing works

Looking at nuclear receptors from a new angle

Helsen, C., & Claessens, F. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.09.009 · Cited by 148 · see citing works

Androgens and spermatogenesis: lessons from transgenic mouse models

Verhoeven, G., Willems, A., Denolet, E., Swinnen, J. V., & Gendt, K. D. (2010) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2009.0117 · Cited by 143 · see citing works

Determinants of Receptor- and Tissue-Specific Actions in Androgen Signaling

Pihlajamaa, P., Sahu, B., & Jänne, O. A. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1034 · Cited by 141 · see citing works

Development and prevalence of castration-resistant prostate cancer subtypes

Vellky, J. E., & Ricke, W. A. (2020) · Neoplasia · doi:10.1016/j.neo.2020.09.002 · Cited by 143 · see citing works

Androgen receptor phosphorylation: biological context and functional consequences

Koryakina, Y. A., Ta, H. Q., & Gioeli, D. G. (2014) · Endocrine Related Cancer · doi:10.1530/erc-13-0472 · Cited by 136 · see citing works

Androgen Receptor-Dependent and -Independent Mechanisms Involved in Prostate Cancer Therapy Resistance

Crona, D. J., & Whang, Y. E. (2017) · Cancers · doi:10.3390/cancers9060067 · Cited by 139 · see citing works

Intracellular Signaling Pathways in Rheumatoid Arthritis

Malemud, C. J. (2013) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000160 · Cited by 134 · see citing works

Sex hormone activity in alcohol addiction: Integrating organizational and activational effects

Lenz, B., Müller, C. P., Stoessel, C., Sperling, W., Biermann, T., Hillemacher, T., Bleich, S., & Kornhuber, J. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.11.001 · Cited by 136 · see citing works

Adaptation or selection—mechanisms of castration-resistant prostate cancer

Zong, Y., & Goldstein, A. S. (2012) · Nature Reviews Urology · doi:10.1038/nrurol.2012.237 · Cited by 133 · see citing works

Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting

Luo, J., Attard, G., Balk, S. P., Bevan, C. L., Burnstein, K. L., Cato, L., Cherkasov, A. R., Bono, J. S. D., Dong, Y., Gao, A. C., et al. (2017) · European Urology · doi:10.1016/j.eururo.2017.11.038 · Cited by 134 · see citing works

Androgen receptor (AR) heterogeneity in prostate cancer and therapy resistance

Jamroze, A., Chatta, G. S., & Tang, D. G. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.06.006 · Cited by 136 · see citing works

Posttranslational Modification of the Androgen Receptor in Prostate Cancer

der Steen, T. V., Tindall, D. J., & Huang, H. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140714833 · Cited by 133 · see citing works

Homosexuality as a Consequence of Epigenetically Canalized Sexual Development

Rice, W. R., Friberg, U., & Sergey Gavrilets, B. (2012) · The Quarterly Review of Biology · doi:10.1086/668167 · Cited by 131 · see citing works

Molecular and cellular mechanisms of castration resistant prostate cancer (Review)

Huang, Y., Jiang, X., Liang, X., & Jiang, G. (2018) · Oncology Letters · doi:10.3892/ol.2018.8123 · Cited by 130 · see citing works

USP10 deubiquitylates the histone variant H2A.Z and both are required for androgen receptor-mediated gene activation

Draker, R., Sarcinella, E., & Cheung, P. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkq1352 · Cited by 129 · see citing works

Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer

Friedlander, T. W., Roy, R., Tomlins, S. A., Ngo, V., Kobayashi, Y., Azameera, A., Rubin, M. A., Pienta, K. J., Chinnaiyan, A. M., Ittmann, M., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-2079 · Cited by 129 · see citing works

Androgen receptor splice variants and prostate cancer: From bench to bedside

Wadosky, K. M., & Koochekpour, S. (2017) · Oncotarget · doi:10.18632/oncotarget.14537 · Cited by 128 · see citing works

Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions

Acaz‐Fonseca, E., Ávila-Rodriguez, M., García‐Segura, L. M., & Barreto, G. E. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.06.002 · Cited by 126 · see citing works

Are androgen receptor variants a substitute for the full-length receptor?

Ji, L., der Steen, T. V., & Tindall, D. J. (2015) · Nature Reviews Urology · doi:10.1038/nrurol.2015.13 · Cited by 124 · see citing works

Castration-resistant prostate cancer: Adaptive responses in the androgen axis

Egan, A., Dong, Y., Zhang, H., Qi, Y., Balk, S. P., & Sartor, O. A. (2013) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2013.09.011 · Cited by 125 · see citing works

Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer

Shiota, M., Yokomizo, A., & Naito, S. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.07.011 · Cited by 124 · see citing works

GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

He, B., Lanz, R. B., Fiskus, W. C., Geng, C., Yi, P., Hartig, S. M., Rajapakshe, K., Shou, J., Wei, L., Shah, S. S., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1421415111 · Cited by 124 · see citing works

Androgen receptor coregulators: recruitment via the coactivator binding groove

van de Wijngaart, D. J., Dubbink, H. J., van Royen, M. E., Trapman, J., & Jenster, G. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.08.007 · Cited by 122 · see citing works

Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer

Moses, M. A., Kim, Y. S., Rivera-Márquez, G. M., Oshima, N., Watson, M. J., Beebe, K. E., Wells, C., Lee, S., Zuehlke, A. D., Shao, H., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-3728 · Cited by 118 · see citing works

Endogenous androgen receptor proteomic profiling reveals genomic subcomplex involved in prostate tumorigenesis

Stelloo, S., Nevedomskaya, E., Kim, Y., Hoekman, L., Bleijerveld, O. B., Mirza, T., Wessels, L. F. A., van Weerden, W. M., Altelaar, A. F. M., Bergman, A. M., et al. (2018) · Oncogene · doi:10.1038/onc.2017.330 · Cited by 118 · see citing works

Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation

Assimon, V. A., Southworth, D. R., & Gestwicki, J. E. (2015) · Biochemistry · doi:10.1021/acs.biochem.5b00801 · Cited by 112 · see citing works

Androgen regulation of gene expression.

(2010) · Advances in cancer research · doi:10.1016/s0065-230x(10)07005-3 · Cited by 117 · see citing works

Molecular Alterations during Progression of Prostate Cancer to Androgen Independence

Saraon, P., Jarvi, K. A., & Diamandis, E. P. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2011.165977 · Cited by 115 · see citing works

SUMO-Specific Protease 1 (SENP1) Reverses the Hormone-Augmented SUMOylation of Androgen Receptor and Modulates Gene Responses in Prostate Cancer Cells

Kaikkonen, S., Jääskeläinen, T. J., Karvonen, U., Rytinki, M. M., Makkonen, H., Gioeli, D. G., Paschal, B. M., & Palvimo, J. J. (2008) · Molecular Endocrinology · doi:10.1210/me.2008-0219 · Cited by 114 · see citing works

Increased Expression of Androgen Receptor Coregulator MAGE-11 in Prostate Cancer by DNA Hypomethylation and Cyclic AMP

Karpf, A. R., Bai, S., James, S. R., Mohler, J. L., & Wilson, E. M. (2009) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-08-0400 · Cited by 115 · see citing works

Anti-androgenic mechanisms of Bisphenol A involve androgen receptor signaling pathway

Wang, H., Ding, Z., Shi, Q.-M., Ge, X., Wang, H.-X., Li, M.-X., Chen, G., Wang, Q., Ju, Q., Zhang, J., et al. (2017) · Toxicology · doi:10.1016/j.tox.2017.06.007 · Cited by 113 · see citing works

CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers

Waddell, A. R., Huang, H., & Liao, D. (2021) · Cancers · doi:10.3390/cancers13122872 · Cited by 110 · see citing works

A Combination of H2A.Z and H4 Acetylation Recruits Brd2 to Chromatin during Transcriptional Activation

Draker, R., Ng, M. K., Sarcinella, E., Ignatchenko, V., Kislinger, T., & Cheung, P. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1003047 · Cited by 108 · see citing works

The mineralocorticoid receptor and its coregulators

Yang, J., & Young, M. J. (2009) · Journal of Molecular Endocrinology · doi:10.1677/jme-09-0031 · Cited by 107 · see citing works

Association of Androgen Receptor CAG Repeat Polymorphism and Polycystic Ovary Syndrome

Shah, N. A., Antoine, H. J., Pall, M., Taylor, K. D., Azziz, R., & Goodarzi, M. O. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0038 · Cited by 108 · see citing works

The hallmarks of castration-resistant prostate cancers

Katsogiannou, M., Ziouziou, H., Karaki, S., Andrieu, C., de Villeneuve, M. H., & Rocchi, P. (2015) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2015.05.003 · Cited by 107 · see citing works

Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor

Zhou, X., Suino-Powell, K. M., Li, J., He, Y., MacKeigan, J. P., Melcher, K., Yong, E., & Xu, H. E. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.085779 · Cited by 105 · see citing works

Progression of prostate cancer: Multiple pathways to androgen independence

Devlin, H.-L., & Mudryj, M. M. (2008) · Cancer Letters · doi:10.1016/j.canlet.2008.06.007 · Cited by 102 · see citing works

Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis

Aleskandarany, M. A., Abduljabbar, R. F., Ashankyty, I., Elmouna, A., Jerjees, D. A., Ali, S., Buluwela, L., Diez, M., Caldas, C., Green, A. R., et al. (2016) · Breast Cancer Research and Treatment · doi:10.1007/s10549-016-3934-5 · Cited by 101 · see citing works

Hormonal regulation of CYP1A expression

Monostory, K., Pascussi, J., Kob́ori, L., & Dvořák, Z. (2009) · Drug Metabolism Reviews · doi:10.1080/03602530903112284 · Cited by 100 · see citing works

Androgen receptor genomic regulation.

Jin, H., Kim, J., & Yu, J. (2013) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2223-4683.2013.09.01 · Cited by 96 · see citing works

The Androgen Receptor and VEGF: Mechanisms of Androgen-Regulated Angiogenesis in Prostate Cancer

Eisermann, K., & Fraizer, G. C. (2017) · Cancers · doi:10.3390/cancers9040032 · Cited by 96 · see citing works

Abiraterone acetate in the treatment of prostate cancer

Thakur, A., Roy, A., Ghosh, A., Chhabra, M., & Banerjee, S. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.02.067 · Cited by 97 · see citing works

Androgen Receptor (AR) Pathophysiological Roles in Androgen Related Diseases in Skin, Metabolism Syndrome, Bone/Muscle and Neuron/Immune Systems: Lessons Learned from Mice Lacking AR in Specific Cells

Chang, C., Yeh, S., Lee, S. O., & Chang, T. (2013) · Nuclear Receptor Signaling · doi:10.1621/nrs.11001 · Cited by 91 · see citing works

Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer

Valdés‐Mora, F., Gould, C. M., Colino‐Sanguino, Y., Qu, W., Song, J. Z., Taylor, K. M., Buske, F. A., Statham, A. L., Nair, S. S., Armstrong, N. J., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01393-8 · Cited by 89 · see citing works

Dysregulation of miR-212 Promotes Castration Resistance through hnRNPH1-Mediated Regulation of AR and AR-V7: Implications for Racial Disparity of Prostate Cancer

Yang, Y., Jia, D., Kim, H., Elmageed, Z. Y. A., Datta, A., Davis, R., Srivastav, S., Moroz, K., Crawford, B. E., Moparty, K., et al. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-1606 · Cited by 89 · see citing works

Androgen Receptor (AR) Coregulators: An Overview

Heinlein, C. A., & Chang, C. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.2.0460 · Cited by 943 · see citing works

0163-769X/02/$20.00/0 Endocrine Reviews 23(2):175–200 Printed in U.S.A. Copyright © 2002 by The Endocrine Society

Heinlein, C. A., & Chang, C. (2013)

Androgen receptor corepressors: An overview

Wang, L., Hsu, C., & Chang, C. (2004) · The Prostate · doi:10.1002/pros.20170 · Cited by 115 · see citing works

Androgen Receptor Coregulators in Prostate Cancer

Rahman, M. M., Miyamoto, H., & Chang, C. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-0746-3 · Cited by 103 · see citing works

Review Androgen Receptor Coregulators in Prostate Cancer: Mechanisms and Clinical Implications

Rahman, M., Miyamoto, H., & Chang, C. (2015)