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Structure of Two in Tandem Human 17β-Hydroxysteroid Dehydrogenase Genes
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Two human 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) genes (h17 beta-HSDI and h17 beta-HSDII) included in tandem within an approximately 13 kilobase pair fragment were isolated from a genomic lambda EMBL3 DNA library using cDNA encoding human 17 beta-HSD (hpE2DH216) as probe. We have determined the complete exon and intron sequences of the two genes as well as their 5' and 3'-flanking regions. Human 17 beta-HSDII contains six exons and five short introns for a total length of 3250 base pairs. The exon sequence of h17 beta-HSDII is identical to the previously reported hpE2DH216 cDNA while the overlapping nucleotide sequences of the corresponding exons and introns of h17 beta-HSDI and h17 beta-HSDII show 89% homology. In addition, we have used the hpE2DH216 cDNA to demonstrate the widespread expression of 17 beta-HSD mRNAs in steroidogenic and peripheral target tissues. These new findings provide the basis for a better understanding of the molecular mechanisms involved in 17 beta-HSD deficiency and peripheral sex steroid metabolism.
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“In the late 1980s, three independent groups reported the cloning of its cDNA, the first of any human HSD (503-505).”
From The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders (2011) · cites this paper as [505]
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Cites
DNA sequencing with chain-terminating inhibitors
Sanger, F., Nicklen, S., & Coulson, A. R. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5463 · Cited by 68,572
Detection of specific sequences among DNA fragments separated by gel electrophoresis
Southern, E. M. (1975) · Journal of Molecular Biology · doi:10.1016/s0022-2836(75)80083-0 · Cited by 32,245
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Feinberg, A. P., & Vogelstein, B. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90418-9 · Cited by 24,512
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,460
Aviv, H., & Leder, P. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1408 · Cited by 6,636
Organization and Expression of Eucaryotic Split Genes Coding for Proteins
Breathnach, R., & Chambon, P. (1981) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.50.070181.002025 · Cited by 4,481
DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.
Tabor, S., & Richardson, C. C. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.14.4767 · Cited by 2,224
Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins
Dynan, W. S., & Tjian, R. (1985) · Nature · doi:10.1038/316774a0 · Cited by 1,147
In vivo sequence requirements of the SV40 early promoter region
Benoist, C., & Chambon, P. (1981) · Nature · doi:10.1038/290304a0 · Cited by 1,074
A multiplicity of CCAAT box-binding proteins
Dorn, A., Bollekens, J. A., Staub, A., Benoist, C. O., & Mathis, D. J. (1987) · Cell · doi:10.1016/0092-8674(87)90513-7 · Cited by 688
Research works printed but not linked: 2
- Lacoste D, Belanger A, Labrie F 1989 Biosynthesis and degradation of androgens in human prostatic cancer cell lines. In: Bradlow H, Castagnetta L, d'Aquino S, Labrie F (eds) Steroid Formation, Degradation and Action in Pe- ripheral Normal and Neoplastic Tissues. Ann New York Acad Sci, NY, in press
- Greene JM 1987 Analysis of RNA structure and synthesis. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seid- man TG, Smith TA, Struhl K (eds) Current Protocols in Molecular Biology. Wiley and Sons, New York, pp 4.6.1- 4.6.5
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Pelletier, G., Luu-The, V., & Labrie, F. (1995) · Brain Research · doi:10.1016/0006-8993(95)01119-6 · Cited by 41
Self-citationBeaudoin, C., Blomquist, C. H., & Tremblay, Y. (1995) · Endocrinology · doi:10.1210/endo.136.9.7649088 · Cited by 39
The search for the familial breast/ovarian cancer gene
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7 Testicular steroidogenesis and androgen use and abuse
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Regulation of Estrogen Action: Role of 17β-Hydroxysteroid Dehydrogenases
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Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line
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Metadata
- Authors
- Luu-The, V., Labrie, C., Simard, J., Lachance, Y., Zhao, H.-F., Couët, J., Leblanc, G., & Labrie, F.
- Affiliations
- Université Laval (CA)
- Venue
- Molecular Endocrinology
- Publisher
- The Endocrine Society
- Published
- 1990-02
- Volume
- 4
- Issue
- 2
- Pages
- 268-275
- ISSN
- 0888-8809 (ISSN-L)
- 1944-9917
- OpenAlex
- W2074285202
- Cited by
- 173
- References
- 27
- Citations by year
- 2024: 1 · 2018: 1 · 2017: 2 · 2015: 5 · 2014: 1
- FWCI
- 5.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Molecular Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Keywords
- 17β-hydroxysteroid dehydrogenase, tandem gene duplication, gene structure, exon-intron organization, 5' and 3' flanking regions, steroidogenic tissues, mRNA expression
- MeSH terms
- Amino Acid Sequence, Base Sequence, Chromosome Mapping, Genes, Humans, Molecular Sequence Data, RNA, Messenger, 17-Hydroxysteroid Dehydrogenases, Restriction Mapping, DNA Probes, Genomic Library
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