Cited by 15,011Multiple Sclerosis Research StudiesHealth Systems, Economic Evaluations, Quality of LifeVoice and Speech Disorders

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Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

Kurtzke, John F.·1983·Neurology

DOI 10.1212/wnl.33.11.1444

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Abstract

One method of evaluating the degree of neurologic impairment in MS has been the combination of grades (0 = normal to 5 or 6 = maximal impairment) within 8 Functional Systems (FS) and an overall Disability Status Scale (DSS) that had steps from 0 (normal) to 10 (death due to MS). A new Expanded Disability Status Scale (EDSS) is presented, with each of the former steps (1,2,3 . . . 9) now divided into two (1.0, 1.5, 2.0 . . . 9.5). The lower portion is obligatorily defined by Functional System grades. The FS are Pyramidal, Cerebellar, Brain Stem, Sensory, Bowel & Bladder, Visual, Cerebral, and Other; the Sensory and Bowel & Bladder Systems have been revised. Patterns of FS and relations of FS by type and grade to the DSS are demonstrated.

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On the evaluation of disability in multiple sclerosis
Kurtzke, J. F. (1961) · Neurology · doi:10.1212/wnl.11.8.686 · Cited by 330
Further notes on disability evaluation in multiple sclerosis, with scale modifications
Kurtzke, J. F. (1965) · Neurology · doi:10.1212/wnl.15.7.654 · Cited by 309
A New Scale for Evaluating Disability in Multiple Sclerosis
Kurtzke, J. F. (1955) · Neurology · doi:10.1212/wnl.5.8.580 · Cited by 305
Appreciating the consequences of disease: the international classification of impairments, disabilities, and handicaps.
Wood, P. (1980) · PubMed · Cited by 247
NEUROLOGIC IMPAIRMENT IN MULTIPLE SCLEROSIS AND THE DISABILITY STATUS SCALE
Kurtzke, J. F. (1970) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1970.tb05808.x · Cited by 156
A PROPOSAL FOR A UNIFORM MINIMAL RECORD OF DISABILITY IN MULTIPLE SCLEROSIS
Kurtzke, J. F. (1981) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1981.tb05548.x · Cited by 127
STUDIES ON THE NATURAL HISTORY OF MULTIPLE SCLEROSIS 6. Clinical and Laboratory Findings at First Diagnosis
Kurtzke, J. F., Beebe, G. W., Nagler, B., Auth, T. L., Kurland, L. T., & Nefzger, M. D. (1972) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1972.tb07525.x · Cited by 68
THE SOCIO-ECONOMIC SCALE
Mellerup, E., Fog, T., Raun, N. E., Colville, P., de Rham, B., Hannah, B., & Kurtzke, J. F. (1981) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1981.tb05549.x · Cited by 53
The effects of isoniazid on patients with multiple sclerosis; preliminary report.
Kurtzke, J. F., & Berlin, L. (1954) · PubMed · doi:10.1164/art.1954.70.4.577 · Cited by 23
ACUTE RESPIRATORY FAILURE IN MULTIPLE SCLEROSIS AND ITS MANAGEMENT
Guthrie, T. C., Kurtzke, J. F., & BERLIN, L. (1952) · Annals of Internal Medicine · doi:10.7326/0003-4819-37-6-1197 · Cited by 20

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Gény, C., Nguyen, J. P., Pollin, B., Fève, A., Ricolfi, F., Césaro, P., & Degos, J. D. (1996) · Movement Disorders · doi:10.1002/mds.870110503 · Cited by 143
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Portaccio, E., Ghezzi, A., Hakiki, B., Martinelli, V., Moiola, L., Patti, F., Mantia, L. L., Mancardi, G., Solaro, C. M., Tola, M. R., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e318224afc9 · Cited by 142
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Lukas, C., Knol, D. L., Sombekke, M. H., Bellenberg, B., Hahn, H. K., Popescu, V., Weier, K., Radue, E. W., Gass, A., Kappos, L., et al. (2014) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2014-308021 · Cited by 142
The multiple sclerosis impact scale (MSIS-29) is a reliable and sensitive measure.
McGuigan, C., & Hutchinson, M. (2004) · PubMed Central · Cited by 141
Development and Validation of the Short Form of a Urinary Quality of Life Questionnaire: SF-Qualiveen
Bonniaud, V., Bryant, D., Parratte, B., & Guyatt, G. H. (2008) · The Journal of Urology · doi:10.1016/j.juro.2008.08.016 · Cited by 145
Demographic and clinical factors associated with changes in employment in multiple sclerosis
Moore, P., Harding, K. E., Clarkson, H., Pickersgill, T. P., Wardle, M., & Robertson, N. P. (2013) · Multiple Sclerosis Journal · doi:10.1177/1352458513481396 · Cited by 142
Cognitive impairment at diagnosis predicts 10-year multiple sclerosis progression
Moccia, M., Lanzillo, R., Palladino, R., Chang, K., Costabile, T., Russo, C. V., Rosa, A. D., Carotenuto, A., Saccà, F., Maniscalco, G. T., et al. (2015) · Multiple Sclerosis Journal · doi:10.1177/1352458515599075 · Cited by 141
The EDSS-Plus, an improved endpoint for disability progression in secondary progressive multiple sclerosis
Cadavid, D., Cohen, J. A., Freedman, M. S., Goldman, M. D., Hartung, H.-P., Havrdová, E., Jeffery, D., Kapoor, R., Miller, A., Sellebjerg, F. T., et al. (2016) · Multiple Sclerosis Journal · doi:10.1177/1352458516638941 · Cited by 145
Resilience Mediates the Longitudinal Relationships Between Social Support and Mental Health Outcomes in Multiple Sclerosis
Koelmel, E., Hughes, A. J., Alschuler, K. N., & Ehde, D. M. (2016) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2016.09.127 · Cited by 144
Comparison of Multiple Sclerosis Lesions at 1.5 and 3.0 Tesla
Sicotte, N. L., Voskuhl, R. R., Bouvier, S. E., Klutch, R., Cohen, M. S., & Mazziotta, J. C. (2003) · Investigative Radiology · doi:10.1097/01.rli.0000065426.07178.f1 · Cited by 141
Comparison of multiple sclerosis clinical subgroups using navigated spin echo diffusion-weighted imaging
Droogan, A. G., Clark, C., Werring, D. J., Barker, G. J., McDonald, W. I., & Miller, D. H. (1999) · Magnetic Resonance Imaging · doi:10.1016/s0730-725x(99)00011-9 · Cited by 142
Multiple Memory Deficits in Patients With Multiple Sclerosis
Litvan, I. (1988) · Archives of Neurology · doi:10.1001/archneur.1988.00520300025012 · Cited by 142
Posterior Fossa Reconstruction
Sahuquillo, J., Rubio, E., Poca, M. A., Rovira, À., Rodríguez‐Baeza, A., & Cervera, C. (1994) · Neurosurgery · doi:10.1227/00006123-199411000-00011 · Cited by 142
HTLV-1 proviral load in peripheral blood mononuclear cells quantified in 100 HAM/TSP patients: A marker of disease progression
Olindo, S., Lézin, A., Cabre, P., Merle, H., Saint-Vil, M., Edimonana-Kaptue, M., Signaté, A., Césaire, R., & Smadja, D. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2005.05.010 · Cited by 142
Final analysis of the European multicenter trial on IFNβ-1b in secondary-progressive MS
Kappos, L., Polman, C. H., Pozzilli, C., Thompson, A. J., Beckmann, K., Dahlke, F., & the European Study Group in Interferon β-1b in Secondary-Progressive MS (2001) · Neurology · doi:10.1212/wnl.57.11.1969 · Cited by 142
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Koldewijn, E. L., Hommes, O. R., Lemmens, W. A. J. G., Debruyne, F. M. J., & Kerrebroeck, P. V. (1995) · The Journal of Urology · doi:10.1016/s0022-5347(01)67258-6 · Cited by 142
A double-blind, randomized trial of IV immunoglobulin treatment in acute optic neuritis
Roed, H., Langkilde, A. R., Sellebjerg, F. T., Lauritzen, M., Bang, P. F., Mørup, A. M., & Frederiksen, J. L. (2005) · Neurology · doi:10.1212/01.wnl.0000152873.82631.b3 · Cited by 142
Modelling the cost effectiveness of interferon beta and glatiramer acetate in the management of multiple sclerosisCommentary: Evaluating disease modifying treatments in multiple sclerosis
Chilcott, J. B., Miller, D. H., McCabe, C., Tappenden, P., O’Hagan, A., Cooper, N. J., Abrams, K., & Claxton, K. (2003) · BMJ · doi:10.1136/bmj.326.7388.522 · Cited by 141
Cerebrotendinous xanthomatosis in Spain: clinical, prognostic, and genetic survey
Pilo‐de‐la‐Fuente, B., Jiménez‐Escrig, A., Lorenzo, J. R., Pardo, J., Arias, M., Arés-Luque, A., Duarte, J., Muñiz‐Pérez, S., & Sobrido, M. J. (2011) · European Journal of Neurology · doi:10.1111/j.1468-1331.2011.03439.x · Cited by 141
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Callosal Contributions to Simultaneous Bimanual Finger Movements
Bonzano, L., Tacchino, A., Roccatagliata, L., Abbruzzese, G., Mancardi, G. L., & Bove, M. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4076-07.2008 · Cited by 136
Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis
Neema, M., Arora, A., Healy, B. C., Guss, Z. D., Brass, S. D., Duan, Y., Buckle, G. J., Glanz, B. I., Stazzone, L., Khoury, S. J., et al. (2009) · Journal of Neuroimaging · doi:10.1111/j.1552-6569.2008.00296.x · Cited by 128
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The association between cognitive impairment and quality of life in patients with early multiple sclerosis
Glanz, B. I., Healy, B. C., Rintell, D. J., Jaffin, S. K., Bakshi, R., & Weiner, H. L. (2010) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2009.11.004 · Cited by 124
BG-12 (dimethyl fumarate): a review of mechanism of action, efficacy, and safety
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Authors: Kurtzke, J. F.
Affiliations: Georgetown University (US)
Corresponding author: Kurtzke, John F.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1983-11
Volume: 33
Issue: 11
Pages: 1444-1444
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.33.11.1444
OpenAlex: W2112165124
Cited by: 15,011
References: 13
Citations by year: 2026: 474 · 2025: 622 · 2024: 692 · 2023: 648 · 2022: 722 · 2021: 781 · 2020: 764 · 2019: 648 · 2018: 603 · 2017: 592 · 2016: 657 · 2015: 634 · 2014: 632 · 2013: 586 · 2012: 581
FWCI: 9.57
Type: journal article
Language: en
Open access: closed
Locations: Neurology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Health Sciences › Health Professions › Speech and Hearing › Voice and Speech Disorders
Keywords: multiple sclerosis, Expanded Disability Status Scale, disability assessment, neurological deficit, functional systems, pyramidal system, cerebellar function, brainstem, sensory impairment, bowel and bladder dysfunction, visual impairment
MeSH terms: Humans, Multiple Sclerosis, Nervous System Diseases, Neurologic Examination

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Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

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