The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Expression of the tyrosine kinase receptor gene trk B is confined to the murine embryonic and adult nervous system
Abstract
We have examined the expression of the trkB gene, which encodes a member of the family of protein tyrosine kinase (TK) transmembrane receptors, during mouse embryogenesis using in situ hybridization and Northern analysis. Transcripts were first detected in the neuroepithelium and in the neural crest of 9.5 day embryos with regions of high expression in the neural folds and at the lateral neuroepithelium. However, during the process of cephalization and development of the peripheral nervous system, transcripts were detected in most neural tissues, including the brain, spinal cord, cranial and spinal ganglia, and along the pathways of axonal tracts extending peripherally. In the adult brain, expression continues in a complex pattern that is confined to specific regions or neuron types. The expression of trkB, a TK receptor, in early embryogenesis, and specifically in neural tissues, is consistent with the notion that this gene plays a role in the events that regulate the development of the nervous system.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene
Geissler, E. N., Ryan, M. A., & Housman, D. E. (1988) · Cell · doi:10.1016/0092-8674(88)90020-7 · Cited by 1,287
Cited by
The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor
Kaplan, D. R., Hempstead, B. L., Martin-Zanca, D., Chao, M. V., & Parada, L. F. (1991) · Science · doi:10.1126/science.1850549 · Cited by 1,379
Self-citationNEUROTROPHINS AND SYNAPTIC PLASTICITY
McAllister, A. K., Katz, L. C., & Lo, D. C. (1999) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.22.1.295 · Cited by 1,337
Klein, R., Nanduri, V., Jing, S., Lamballe, F., Tapley, P., Bryant, S., Cordon-Cardo, C., Jones, K. R., Reichardt, L. F., & Barbacid, M. (1991) · Cell · doi:10.1016/0092-8674(91)90628-c · Cited by 958
Self-citationMurer, M. G., Yan, Q., & Raisman-Vozari, R. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00014-9 · Cited by 874
Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB
Berkemeier, L. R., Winslow, J. W., Kaplan, D. R., Nikolics, K., Goeddel, D. V., & Rosenthal, A. (1991) · Neuron · doi:10.1016/0896-6273(91)90287-a · Cited by 836
Soppet, D., Escandon, E., Maragos, J., Middlemas, D. S., Raid, S. W., Blair, J., Burton, L. E., Stanton, B. R., Kaplan, D. R., Hunter, T., et al. (1991) · Cell · doi:10.1016/0092-8674(91)90396-g · Cited by 820
Klein, R., Smeyne, R. J., Wurst, W., Long, L. K., Auerbach, B. A., Joyner, A. L., & Barbacid, M. (1993) · Cell · doi:10.1016/0092-8674(93)90683-h · Cited by 699
Self-citationTrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment
Li, Y., Luikart, B. W., Birnbaum, S., Chen, J., Kwon, C.-H., Kernie, S. G., Bassel-Duby, R., & Parada, L. F. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.023 · Cited by 634
Self-citationLevine, E. S., Dreyfus, C. F., Black, I. B., & Plummer, M. R. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.17.8074 · Cited by 611
Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex.
Castrén, E., Zafra, F., Thoenen, H., & Lindholm, D. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.20.9444 · Cited by 513
Eide, F. F., Vining, E. R., Eide, B. L., Zang, K., Wang, X.-Y., & Reichardt, L. F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-10-03123.1996 · Cited by 474
Differentiation of mouse embryonic stem cells into a defined neuronal lineage
Bibel, M., Richter, J., Schrenk, K., Tucker, K. L., Staiger, V., Korte, M., Goetz, M., & Barde, Y.-A. (2004) · Nature Neuroscience · doi:10.1038/nn1301 · Cited by 450
Lai, C., & Lemke, G. (1991) · Neuron · doi:10.1016/0896-6273(91)90167-x · Cited by 443
Eisch, A. J., Bolaños, C. A., de Wit, J., Simonak, R. D., Pudiak, C. M., Barrot, M., Verhaagen, J., & Nestler, E. J. (2003) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.08.003 · Cited by 420
Vaynman, S., & Gomez-Pinilla, F. (2005) · Neurorehabilitation and Neural Repair · doi:10.1177/1545968305280753 · Cited by 420
S ELECTIVITY IN N EUROTROPHIN S IGNALING : Theme and Variations
Segal, R. A. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131421 · Cited by 383
The trk B tyrosine protein kinase is a receptor for neurotrophin-4
Klein, R., Lamballe, F., Bryant, S., & Barbacid, M. (1992) · Neuron · doi:10.1016/0896-6273(92)90209-v · Cited by 326
Self-citationContiguous patterns of c-kit and steel expression: analysis of mutations at the W and Sl loci
Motro, B., Kooy, D. V. D., Rossant, J., Reith, A., & Bernstein, A. (1991) · Development · doi:10.1242/dev.113.4.1207 · Cited by 296
Keeping track of neurotrophin receptors
Bothwell, M. (1991) · Cell · doi:10.1016/0092-8674(91)90540-f · Cited by 294
Widenfalk, J., Lundströmer, K., Jubran, M., Brené, S., & Olson, L. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-10-03457.2001 · Cited by 289
Knusel, B., Beck, K., Winslow, J., Rosenthal, A., Burton, L., Widmer, H., Nikolics, K., & Hefti, F. (1992) · The Journal of Neuroscience · doi:10.1523/jneurosci.12-11-04391.1992 · Cited by 276
Koponen, E., Võikar, V., Riekki, R., Saarelainen, T., Rauramaa, T., Rauvala, H., Taira, T., & Castrén, E. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.01.006 · Cited by 170
Henneberger, C., Jüttner, R., Rothe, T., & Grantyn, R. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.2.595 · Cited by 87
Li, Y., Yui, D., Luikart, B. W., McKay, R. M., Li, Y., Rubenstein, J. L., & Parada, L. F. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1212899109 · Cited by 81
Self-citationCheng, Q., & Yeh, H. H. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2002.037846 · Cited by 73
Metadata
- Authors
- Klein, R., Martin-Zanca, D., Acid, M. B., & Parada, L. F.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 1990-08-01
- Volume
- 109
- Issue
- 4
- Pages
- 845-850
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2343983395
- Cited by
- 376
- References
- 1
- FWCI
- 11.62
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
