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Cited by 188Physical Activity and HealthCardiovascular and exercise physiologyObesity, Physical Activity, Diet

Daily total physical activity level and premature death in men and women: results from a large-scale population-based cohort study in Japan (JPHC study)

Inoue, Manami, Iso, Hiroyasu, Yamamoto, Seiichiro, Kurahashi, Norie, Iwasaki, Motoki, Sasazuki, Shizuka, Tsugane, Shoichiro·2008·Annals of Epidemiology
DOI 10.1016/j.annepidem.2008.03.008
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Abstract

Purpose The impact of daily total physical activity level on premature deaths has not been fully clarified in non-Western, relatively lean populations. We prospectively examined the association between daily total physical activity level (METs/day) and subsequent risk of all-cause mortality and mortalities from cancer, heart disease, and cerebrovascular disease.Methods A total of 83,034 general Japanese citizens ages 45-74 years who responded to the questionnaire in 1995-1999 were followed for any cause of death through December 2005. Mutlivariate-adjusted hazard ratios were calculated with a Cox proportional hazards model controlling for potential confounding factors.Results During follow-up, a total of 4564 deaths were recorded. Compared with subjects in the lowest quartile, increased daily total physical activity was associated with a significantly decreased risk of all-cause mortality in both sexes (hazard ratios for the second, third, and highest quartiles were: men, 0.79, 0.82, 0.73 and women, 0.75, 0.64, 0.61, respectively). The decreased risk was observed regardless of age, frequency of leisure-time sports or physical exercise, or obesity status, albeit with a degree of risk attenuation among those with a high body mass index. A significantly decreased risk was similarly observed for death from cancer and heart disease in both sexes, and from cerebrovascular disease in women.Conclusion Greater daily total physical activity level, either from occupation, daily life, or leisure time, may be of benefit in preventing premature death.

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  • Five studies assessed daily total sitting time by self-report, and one study used objective measurement of daily sedentary time.

    “Five studies assessed daily total sitting time by self-report[10,11,32-34]. One study used objective measurement of daily sedentary time[30].”

    From Daily Sitting Time and All-Cause Mortality: A Meta-Analysis (2013) · cites this paper as [34]

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Authors
Inoue, M., Iso, H., Yamamoto, S., Kurahashi, N., Iwasaki, M., Sasazuki, S., & Tsugane, S.
Affiliations
  • National Cancer Centre Japan (JP)
  • The University of Osaka (JP)
Corresponding author
Inoue, Manami
ORCID
Venue
Annals of Epidemiology
Publisher
Elsevier BV
Published
2008-07
Volume
18
Issue
7
Pages
522-530
ISSN
1047-2797 (ISSN-L)
DOI
10.1016/j.annepidem.2008.03.008
OpenAlex
W2102472373
Cited by
188
References
37
Citations by year
2025: 7 · 2024: 5 · 2023: 25 · 2022: 14 · 2021: 12 · 2020: 6 · 2019: 16 · 2018: 10 · 2017: 10 · 2016: 6 · 2015: 16 · 2014: 8 · 2013: 16 · 2012: 11
FWCI
5.64
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Annals of Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
physical activity, all-cause mortality, premature mortality, cancer mortality, cardiovascular mortality, cerebrovascular disease mortality, sex differences, body mass index, occupational physical activity, leisure-time physical activity, Japanese adults
MeSH terms
Aged, Cause of Death, Female, Humans, Japan, Life Expectancy, Male, Middle Aged, Mortality, Motor Activity, Surveys and Questionnaires, Risk Factors, Cohort Studies, Confounding Factors, Epidemiologic, Multivariate Analysis, Proportional Hazards Models

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