The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Fetal, Infant, and Childhood Growth Are Predictors of Coronary Heart Disease, Diabetes, and Hypertension in Adult Men and Women
Abstract
Many human fetuses have to adapt to a limited supply of nutrients. In doing so they permanently change their structure and metabolism. These programmed changes may be the origins of a number of diseases in later life, including coronary heart disease, hypertension, and noninsulin- dependent diabetes. We review epidemiologic studies in which the incidence of these diseases has been related to the recorded, early growth of individuals, while considering factors in the adult lifestyle, such as obesity and socioeconomic status. We discuss possible mechanisms. For hypertension these mechanisms include placentation, maternal blood pressure, fetal undernutrition; childhood growth, activation of the renin-angiotensin system, renal structure, programming of the hypothalamic-pituitary-adrenal axis, vascular structure, and sympathetic nervous activity. For noninsulin-dependent diabetes we discuss mechanisms concerning both insulin resistance and insulin deficiency. We include a review of evidence for the programming of serum cholesterol and clotting factor concentrations. We address the timing of critical windows for coronary heart disease, reviewing studies that allow assessment of the relative importance of fetal, infant, and childhood growth. We argue for a research strategy that combines clinical, animal, and epidemiological studies.
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“Moreover, it is well documented that, in comparison with children born at term, those born prematurely are more likely to present cerebral palsy, sensory deficits, learning disabilities, and respiratory illnesses [5,6,7,8,9,10,11,12,13].”
From A Comprehensive Review on Social Inequalities and Pregnancy Outcome—Identification of Relevant Pathways and Mechanisms (2022) · cites this paper as [10]
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Fetal origins of coronary heart disease
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Self-citationFetal nutrition and cardiovascular disease in adult life
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Self-citationGlucose tolerance in adults after prenatal exposure to famine
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Gluckman, P. D., Cutfield, W., Hofman, P., & Hanson, M. A. (2005) · Early Human Development · doi:10.1016/j.earlhumdev.2004.10.003 · Cited by 326
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Maggi, S., Irwin, L. J., Siddiqi, A., & Hertzman, C. (2010) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2010.01817.x · Cited by 322
Dubé, E., Gravel, A., Martin, C., Desparois, G., Moussa, I., Ethier-Chiasson, M., Forest, J.-C., Giguère, Y., Masse, A., & Lafond, J. (2012) · Biology of Reproduction · doi:10.1095/biolreprod.111.098095 · Cited by 180
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Witt, W. P., Cheng, E. R., Wisk, L. E., Litzelman, K., Chatterjee, D., Mandell, K., & Wakeel, F. (2014) · American Journal of Public Health · doi:10.2105/ajph.2013.301688 · Cited by 71
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Atrash, H., Jack, B. W., & Johnson, K. (2008) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e328317a27c · Cited by 58
Impact of Chronodisruption during Primate Pregnancy on the Maternal and Newborn Temperature Rhythms
Serón-Ferré, M., Forcelledo, M. L., Torres-Farfan, C., Valenzuela, F. J., Rojas, A., Vergara, M., Rojas-Garcia, P. P., Recabarren, M. P., & Valenzuela, G. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057710 · Cited by 55
Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy
Chico, R. M., & Chandramohan, D. (2011) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2011.02765.x · Cited by 38
Spichiger, C., Torres-Farfan, C., Galdames, H. A., Mendez, N., Alonso-Vazquez, P., & Richter, H. G. (2015) · Physiological Genomics · doi:10.1152/physiolgenomics.00023.2015 · Cited by 34
Metadata
- Authors
- Osmond, C., & Barker, D. J.
- Affiliations
- MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, United Kingdom. co@mrc.soton.ac.uk
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2000-06-01
- Volume
- 108
- Issue
- suppl 3
- Pages
- 545-553
- ISSN
- 0091-6765
- 1552-9924
- Cited by
- 307
- References
- 12
- Language
- en
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