Cited by 134Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major DepressionMental Health Research Topics

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Does emotion predict the course of major depressive disorder? A review of prospective studies

Morris, Bethany H., Bylsma, Lauren M., Rottenberg, Jonathan·2009·British Journal of Clinical Psychology

DOI 10.1348/014466508x396549

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Abstract

Purpose. Emotional dysfunction is a hallmark of major depressive disorder (MDD). There has been wide interest in identifying the nature and significance of emotional deficits in MDD. Given the paramount goal of identifying etiological markers of MDD that can sharpen prevention and treatment efforts, researchers have pursued emotion as a functionally significant factor and predictor of clinical course in MDD. This review is the first to summarize the literature examining emotion as a predictor of the clinical course of MDD. Method. We conducted a systematic review of all published studies reporting on the prospective relationship between positive and negative emotionality (PE and NE) – measured at the state or trait level – and the longitudinal course of MDD in diagnosed adults. Physiological, behavioural, and subjective indices of emotion were considered. The primary analyses encompassed 28 research reports that included data from 3,798 participants and tested a total of 60 hypotheses. Results. Lower levels of PE predicted poorer MDD course with some consistency. Paradoxically, both lower levels of state NE and higher levels of trait NE predicted poorer MDD course. The relationships between emotionality and MDD course generally held even after initial depression symptom severity was taken into account. Conclusion. Emotion shows promise as a predictor of MDD course. Implications of these data for current theories of emotion and MDD, the apparently divergent relation between state and trait NE and course, and future directions to further clarify the functional significance of emotion in the context of MDD are discussed.

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Savor the Memory: A Reminiscence Exercise to Increase Positive Emotions and Reduce Depression Risk in Anxious Individuals
Morris, B. H. (2014) · Digital Commons - University of South Florida (University of South Florida)
Self-citation
Emotion-modulated startle and the course of major and minor depression
Taylor-Clift, A. (2012) · Digital Commons - University of South Florida (University of South Florida)
The Effect of Stress on Hedonic Capacity in Generalized Anxiety Disorder: A Prospective Experimental Study of One Potential Pathway to Depression
Morris, B. H. (2009) · Digital Commons - University of South Florida (University of South Florida)
Self-citation
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Authors: Morris, B. H., Bylsma, L. M., & Rottenberg, J.
Affiliations: University of South Florida (US)
Corresponding author: Rottenberg, Jonathan
ORCID: Bylsma, Lauren M.
Rottenberg, Jonathan
Venue: British Journal of Clinical Psychology
Publisher: Wiley
Published: 2009-09
Volume: 48
Issue: 3
Pages: 255-273
ISSN: 0144-6657 (ISSN-L)
2044-8260
DOI: 10.1348/014466508x396549
OpenAlex: W1980099020
Cited by: 134
References: 105
Citations by year: 2026: 9 · 2025: 9 · 2024: 6 · 2023: 14 · 2022: 23 · 2021: 9 · 2020: 7 · 2019: 6 · 2018: 7 · 2017: 5 · 2016: 5 · 2015: 11 · 2014: 2 · 2013: 4 · 2012: 9
FWCI: 0.84
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 577 d)
Locations: British Journal of Clinical Psychology (publishedVersion)
PubMed (publishedVersion)
Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Keywords: major depressive disorder, clinical course, positive affectivity, negative affectivity, emotional dysfunction
MeSH terms: Adult, Affective Symptoms, Depression, Major Depressive Disorder, Emotions, Humans, Longitudinal Studies, Patient Acceptance of Health Care, Personality Assessment, Prognosis, Prospective Studies

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Does emotion predict the course of major depressive disorder? A review of prospective studies

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