A meta-analysis of emotional reactivity in major depressive disorder
Abstract
Three alternative views regarding how Major Depressive Disorder (MDD) alters emotional reactivity have been featured in the literature: positive attenuation (reduced positive reactivity), negative potentiation (increased negative reactivity), and emotion context insensitivity (ECI; reduced positive and negative reactivity). Although empirical studies have accumulated on emotional reactivity in MDD, this report is to our knowledge the first systematic quantitative review of this topic area. In omnibus analyses of 19 laboratory studies comparing the emotional reactivity of healthy individuals to that of individuals with MDD, MDD was characterized by reduced emotional reactivity to both positively and negatively valenced stimuli, with the reduction larger for positive stimuli (d=-.53) than for negative stimuli (d=-.25). Results were similar when 3 major emotion response systems (self-reported experience, expressive behavior, and peripheral physiology) were analyzed individually. The ECI view of emotional reactivity in MDD is well supported by laboratory data. Implications for the understanding of emotions in MDD are discussed.
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A meta-analysis found that depressed individuals show less context-appropriate emotional reactivity to both positive and negative stimuli.
“a recent meta-analysis of the experimental literature found that depressed individuals exhibit less context appropriate emotional reactivity to both positive and to negative stimuli (Bylsma, Morris, & Rottenberg, 2008).”
From Psychological flexibility as a fundamental aspect of health (2010) · cites this paper as Bylsma, Morris, & Rottenberg, 2008
Depression is associated with reduced physiological reactivity to positive stimuli.
“Depression, associated with less intense emotions, has also consistently been associated with reduced physiological reactivity to positive stimuli (Bylsma et al., 2008; Sloan and Sandt, 2010)”
From Atypical interoception as a common risk factor for psychopathology: A review (2021) · cites this paper as Bylsma et al., 2008
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Emotion context insensitivity in depression: Toward an integrated and contextualized approach
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Hoorelbeke, K., Marchetti, I., Schryver, M. D., & Koster, E. H. W. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.02.001 · Cited by 101 · see citing works
Shim, M., Im, C., Kim, Y.-W., & Lee, S.-H. (2018) · NeuroImage: Clinical · doi:10.1016/j.nicl.2018.06.012 · Cited by 86 · see citing works
Enhanced Anger Reactivity and Reduced Distress Tolerance in Major Depressive Disorder
Ellis, A. J., Vanderlind, W. M., & Beevers, C. G. (2013) · Cognitive Therapy and Research · doi:10.1007/s10608-012-9494-z · Cited by 99 · see citing works
Gruber, J., Kogan, A., Mennin, D. S., & Murray, G. (2013) · Journal of Abnormal Psychology · doi:10.1037/a0034425 · Cited by 98 · see citing works
Emotional information processing in depression and burnout: an eye-tracking study
Bianchi, R., & Laurent, É. (2015) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-014-0549-x · Cited by 79 · see citing works
The influence of depression symptoms on exploratory decision-making
Blanco, N. J., Otto, A. R., Maddox, W. T., Beevers, C. G., & Love, B. C. (2013) · Cognition · doi:10.1016/j.cognition.2013.08.018 · Cited by 93 · see citing works
- Authors
- Bylsma, L. M., Morris, B. H., & Rottenberg, J.
- Affiliations
- University of South Florida (US)
- Corresponding author
- Rottenberg, Jonathan
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2008-04
- Volume
- 28
- Issue
- 4
- Pages
- 676-691
- ISSN
- 0272-7358 (ISSN-L)
- OpenAlex
- W2035505019
- Cited by
- 933
- References
- 133
- Citations by year
- 2026: 45 · 2025: 60 · 2024: 62 · 2023: 64 · 2022: 43 · 2021: 77 · 2020: 73 · 2019: 68 · 2018: 63 · 2017: 59 · 2016: 59 · 2015: 63 · 2014: 45 · 2013: 48 · 2012: 30
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- major depressive disorder, emotional reactivity, expressive behavior
- MeSH terms
- Affect, Major Depressive Disorder, Humans
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