Multi-wavelength photoplethysmography method for skin arterial pulse extraction
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In this work, we present a multi-wavelength (MW) PPG method exploiting the wavelength dependence of light penetration in skin tissue to provide depth resolution of skin blood pulsation. The MW PPG system requires two to three light sources in different wavelengths and extracts the arterial blood pulsation through a multi-wavelength multi-layer light-skin interaction model, which removes the capillary pulsation (determined from the short-wavelength PPG signal) from the long-wavelength PPG signal using absorption weighting factors that are quasi-analytically calibrated. The extracted pulsations are used to calculate blood pressure (BP) through pulse transit time (PTT), and the results are compared with those obtained from the single wavelength PPG method. The comparative study is clinically performed on 20 subjects including 10 patients diagnosed with cardiovascular diseases and 10 healthy subjects. The result demonstrates that the MW PPG method significantly improves the measurement accuracy of systolic BP (SBP), reducing the mean absolute difference between the reference and the estimated SBP values from 5.7 mmHg (for single-wavelength PPG) to 2.9 mmHg (for three-wavelength PPG).
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In a study by Liu et al., using three wavelengths instead of single-wavelength PPG increased accuracy about two times.
“For example, in a study by Liu et al., where instead of using a single wavelength PPG, three wavelengths were used, the accuracy was increased about two times [114].”
From The Current State of Optical Sensors in Medical Wearables (2022) · cites this paper as [114]
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- Authors
- Liu, J., Yan, B. P.-Y., Dai, W.-X., Ding, X.-R., Zhang, Y.-T., & Zhao, N.
- Affiliations
- Chinese University of Hong Kong (HK)
- Venue
- Biomedical Optics Express
- Publisher
- Optica Publishing Group
- Published
- 2016-09-27
- Volume
- 7
- Issue
- 10
- Pages
- 4313
- ISSN
- 2156-7085 (ISSN-L)
- PMC
- PMC5102532
- OpenAlex
- W2526662839
- Cited by
- 107
- References
- 18
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 12 · 2023: 17 · 2022: 17 · 2021: 10 · 2020: 12 · 2019: 10 · 2018: 9 · 2017: 1
- FWCI
- 3.21
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Biomedical Optics Express (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Chow Yuk Ho Technology Centre for Innovative Medicine (TIM Seed Grant)
- Innovation and Technology Commmission of Hong Kong (ITS/275/15FP)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Keywords
- light penetration depth, pulse transit time, systolic blood pressure estimation, cardiovascular disease
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