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Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes
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Impaired fusion between Rab4-positive and Rab11-positive endosomes leads to increased overlap between Rab4 and Rab11 compartments, thereby disrupting AMPAR trafficking.
“Previous work proposed a model that impaired fusion between Rab4-positive and Rab11-positive endosomes leads to increased overlap between Rab4 and Rab11 compartments, thereby disrupting AMPAR trafficking (Hoogenraad et al., 2010).”
From Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling (2025) · cites this paper as Hoogenraad et al., 2010
Impaired fusion between Rab4- and Rab11-positive endosomal compartments reduces surface expression of GluA1- and GluA2-containing AMPARs.
“Impaired fusion between Rab4- and Rab11-positive endosomal compartments has been shown to reduce the surface expression of GluA1-and GluA2-containing AMPARs (Hoogenraad et al., 2010; Chiu et al., 2017).”
From Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling (2025) · cites this paper as Hoogenraad et al., 2010
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Citations
Cites
Rab GTPases as coordinators of vesicle traffic
Stenmark, H. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2728 · Cited by 3,413
AMPA Receptor Trafficking and Synaptic Plasticity
Malinow, R., & Malenka, R. C. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142758 · Cited by 2,588
The Postsynaptic Architecture of Excitatory Synapses: A More Quantitative View
Sheng, M., & Hoogenraad, C. C. (2007) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.060805.160029 · Cited by 1,003
Self-citationRecycling Endosomes Supply AMPA Receptors for LTP
Park, M., Penick, E. C., Edwards, J. G., Kauer, J. A., & Ehlers, M. D. (2004) · Science · doi:10.1126/science.1102026 · Cited by 730
McBride, H. M., Rybin, V., Murphy, C., Giner, A., Teasdale, R., & Zerial, M. (1999) · Cell · doi:10.1016/s0092-8674(00)81966-2 · Cited by 520
ORGANELLES AND TRAFFICKING MACHINERY FOR POSTSYNAPTIC PLASTICITY
Kennedy, M. J., & Ehlers, M. D. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112808 · Cited by 346
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Metadata
- Authors
- Hoogenraad, C. C., Popa, I., Futai, K., Sanchez-Martinez, E., Wulf, P. S., van Vlijmen, T., Dortland, B. R., Oorschot, V., Govers, R., Monti, M., Heck, A. J. R., Sheng, M., Klumperman, J., Rehmann, H., Jaarsma, D., Kapitein, L. C., & van der Sluijs, P.
- Venue
- PLoS Biology
- Publisher
- Public Library of Science (PLoS)
- Published
- 2010-01-19
- Volume
- 8
- Issue
- 1
- Pages
- e1000283
- ISSN
- 1545-7885
- PMC
- PMC2808209
- Cited by
- 101
- References
- 6
- Language
- en
- Update notices
- correction (2010-09-02)
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