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RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes
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EHBP1 as a key endosomal protein plays essential roles in endosomal sorting and trafficking.
“EHBP1 as a key endosomal protein plays essential roles in endosomal sorting and trafficking.28,72–74”
From EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis (2025) · cites this paper as [72]
The study extended the known Retromer regulators to include DENND4A and DENND4C, TBC1D13, and a TBC1D1/TBC1D4 heterodimer, establishing mechanistic links between Retromer and the switching of RAB10 and RAB35.
“We have now extended these regulators to include DENND4A and DENND4C, TBC1D13, and a TBC1D1/TBC1D4 heterodimer, and in so doing, established mechanistic links between Retromer and the switching of RAB10 and RAB35; two RAB GTPases previously linked to the regulation of endosomal cargo recycling85,88–90,92,96,101,121,122.”
From Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation (2025) · cites this paper as [88]
Activation of RAB10 is heavily implicated in general endosomal cargo recycling.
“Activation of RAB10 is heavily implicated in general endosomal cargo recycling85–93”
From Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation (2025) · cites this paper as [88]
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Self-citationEHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis
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Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation
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Metadata
- Authors
- Wang, P., Liu, H., Wang, Y., Liu, O., Zhang, J., Gleason, A., Yang, Z., Wang, H., Shi, A., & Grant, B. D.
- Venue
- PLOS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2016-06-06
- Volume
- 12
- Issue
- 6
- Pages
- e1006093
- ISSN
- 1553-7404
- PMC
- PMC4894640
- Cited by
- 71
- References
- 0
- Language
- en
- Funders
- National Institute of General Medical Sciences (GM067237)
- National Institutes of Health (R01 GM103995)
- National Natural Science Foundation of China (81371418)
- Natural Science Foundation of Hubei Province (2013CFA063)
- Specialized Research Fund for the Doctoral Program of Higher Education (20130142110071)
- Program for New Century Excellent Talents in University (NCET-13-0234)
- Junior Thousand Talents Program of China
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