Evidence-based guidelines for mental, neurological, and substance use disorders in low- and middle-income countries: Summary of WHO recommendations
Open accessAbstract
Why Evidence-Based Guidelines Are Urgently NeededMental, neurological, and substance use (MNS) disorders are highly prevalent and are responsible for 14% of the global burden of disease expressed in disabilityadjusted life years (DALYs) [1].The resources that have been provided in countries to tackle the huge burden are insufficient, inequitably distributed, and inefficiently used, which results in a large majority of people with these disorders receiving no care at all [2-7].Even when available, treatment and care often is neither evidence-based nor of high quality.The result is a large treatment gap, with more than 75% in many low-and middleincome countries (LAMIC).In order to reduce the gap, the World Health Organization (WHO) launched the Mental Health Gap Action ProgrammeThe Policy Forum allows health policy makers around the world to discuss challenges and opportunities for improving health care in their societies.
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The WHO mhGAP Guidelines recommend using Screening, Brief Intervention, and Referral to Treatment (SBIRT) to reduce unhealthy alcohol use.
“The WHO Mental Health Gap Action Programme Guidelines (mhGAP)(Dua et al., 2011; WHO, 2008a) recommend using Screening, Brief Intervention, and Referral to Treatment (SBIRT) (Babor & Higgins-Biddle, 2001) to reduce UAU.”
From Mobile technology and task shifting to improve access to alcohol treatment services in Mozambique (2022) · cites this paper as Dua et al., 2011
Resources and infrastructure to treat unhealthy alcohol use in Mozambique are limited, with 75-90% of people with behavioral health issues receiving no care due to provider scarcity and geographic distribution.
“However, resources and infrastructure to treat UAU in Mozambique are limited; 75–90% of people with behavioral health issues receive no care because of provider scarcity and geographic distribution (Demyttenaere et al., 2004; dos Santos et al., 2016; Dua et al., 2011).”
From Mobile technology and task shifting to improve access to alcohol treatment services in Mozambique (2022) · cites this paper as Dua et al., 2011
The mhGAP-IG has been found to be effective in offering basic mental health services through primary health care systems.
“The mhGAP-IG has been found to be effective in offering basic mental health services through primary health care systems [15, 16].”
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- Authors
- Dua, T., Barbui, C., Clark, N., Fleischmann, A., Poznyak, V., van Ommeren, M., Yasamy, M. T., Ayuso-Mateos, J. L., Birbeck, G. L., Drummond, C., Freeman, M., Giannakopoulos, P., Levav, I., Obot, I. S., Omigbodun, O., Patel, V., Phillips, M., Prince, M., Rahimi-Movaghar, A., Rahman, A., Sander, J. W., Saunders, J. B., Servili, C., Rangaswamy, T., Unützer, J., Ventevogel, P., Vijayakumar, L., Thornicroft, G., & Saxena, S.
- Affiliations
- World Health Organization (CH)
- University of Verona (IT)
- Michigan State University (US)
- King's College London (GB)
- Department of Health (ZA)
- Israel Ministry of Health (IL)
- University of Uyo (NG)
- University of Ibadan (NG)
- London School of Hygiene & Tropical Medicine (GB)
- Emory University (US)
- National Hospital for Neurology and Neurosurgery (GB)
- The University of Sydney (AU)
- University of Washington Medical Center (US)
- HealthNet TPO (NL)
- Voluntary Health Services Hospital (IN)
- Corresponding author
- Saxena, Shekhar
- ORCID
- Dua, Tarun
- Barbui, Corrado
- Clark, Nicolas
- Fleischmann, Alexandra
- Poznyak, Vladimir
- Yasamy, M. Taghi
- Birbeck, Gretchen L.
- Drummond, Colin
- Freeman, Melvyn
- Obot, Isidore S.
- Omigbodun, Olayinka
- Patel, Vikram
- Phillips, Michael
- Prince, Martin
- Sander, Josemir W.
- Saunders, John B.
- Servili, Chiara
- Unützer, Jürgen
- Ventevogel, Peter
- Thornicroft, Graham
- Saxena, Shekhar
- Venue
- PLoS Medicine
- Publisher
- Public Library of Science (PLoS)
- Published
- 2011-11-15
- Volume
- 8
- Issue
- 11
- Pages
- e1001122
- ISSN
- 1549-1277 (ISSN-L)
- 1549-1676
- PMC
- PMC3217030
- OpenAlex
- W2051919615
- Cited by
- 384
- References
- 30
- Citations by year
- 2026: 9 · 2025: 16 · 2024: 15 · 2023: 26 · 2022: 35 · 2021: 30 · 2020: 27 · 2019: 21 · 2018: 24 · 2017: 34 · 2016: 32 · 2015: 36 · 2014: 32 · 2013: 27 · 2012: 20
- FWCI
- 34.37
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS Medicine (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (publishedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- UCL Discovery (University College London) (submittedVersion)
- Hispana (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Biblos-e Archivo (Universidad Autónoma de Madrid) (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya) (submittedVersion, cc-by)
- Funders
- American Psychiatric Foundation
- United Nations Population Fund
- Wellcome Trust (091834, 080002)
- National Institute for Health and Care Research (RP-PG-0609-10162)
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Surgery
- Keywords
- mental, neurological and substance use disorders, WHO Mental Health Gap Action Programme, evidence-based clinical guidelines, low- and middle-income countries, treatment gap, access to mental health care, global burden of disease, health policy
- MeSH terms
- Mental Disorders, Developing Countries, Health Planning Guidelines, Humans, Income, Mental Health Services, Nervous System Diseases, Patient Care Management, World Health Organization, Evidence-Based Medicine, Substance-Related Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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