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Inhibition of NF-κB signaling in IKKβF/F;LysM Cre mice causes motor deficits but does not alter pathogenesis of Spinocerebellar ataxia type 1

Ferro, Austin, Qu, Wenhui, Lukowicz, Abigail, Svedberg, Daniel, Johnson, Andrea, Cvetanovic, Marija·2018·PLOS ONE

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  1. HT Orr, 2007, Trinucleotide Repeat Disorders, Annu. Rev. Neurosci, 30, 575, 10.1146/annurev.neuro.29.051605.113042 · DOI
  2. S Banfi, 1996, Cloning and developmental expression analysis of the murine homolog of the spinocerebellar ataxia type 1 gene (Sca1), Hum. Mol. Genet, 5, 33, 10.1093/hmg/5.1.33 · DOI
  3. HL Paulson, 2017, Polyglutamine spinocerebellar ataxias—from genes to potential treatments, Nat. Rev. Neurosci, 18, 613, 10.1038/nrn.2017.92 · DOI
  4. K Seidel, 2012, Brain pathology of spinocerebellar ataxias, Acta Neuropathol, 124, 1, 10.1007/s00401-012-1000-x · DOI
  5. A Matilla-Dueñas, 2008, Clinical, genetic, molecular, and pathophysiological insights into spinocerebellar ataxia type 1, Cerebellum, 7, 106, 10.1007/s12311-008-0009-0 · DOI
  6. G Oz, 2010, Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status, Mov. Disord, 25, 1253, 10.1002/mds.23067 · DOI
  7. G Oz, 2010, Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1, J. Neurosci, 30, 3831, 10.1523/JNEUROSCI.5612-09.2010 · DOI
  8. HY Zoghbi, 2009, Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, Spinocerebellar ataxia type 1, J. Biol. Chem, 284, 7425, 10.1074/jbc.R800041200 · DOI
  9. HE Nino, 1980, A family with hereditary ataxia: HLA typing 39, Neurology, 30, 12, 10.1212/WNL.30.1.12 · DOI
  10. M Cvetanovic, 2015, Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1, Neuroscience, 289, 289, 10.1016/j.neuroscience.2015.01.003 · DOI
  11. S Thameem Dheen, 2007, Microglial Activation and its Implications in the Brain Diseases, Curr. Med. Chem, 14, 1189, 10.2174/092986707780597961 · DOI
  12. M Prinz, 2011, Microglia in the CNS: Immigrants from another world, Glia, 59, 177, 10.1002/glia.21104 · DOI
  13. F Ginhoux, 2010, Science, Science, 330, 841
  14. P Squarzoni, 2014, Microglia Modulate Wiring of the Embryonic Forebrain, Cell Rep, 8, 1271, 10.1016/j.celrep.2014.07.042 · DOI
  15. AH Stephan, 2012, The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease, Annu. Rev. Neurosci, 35, 369, 10.1146/annurev-neuro-061010-113810 · DOI · Paper page
  16. M Perez-Pouchoulen, 2015, Morphological and Phagocytic Profile of Microglia in the Developing Rat Cerebellum, eNeuro, 2, 1, 10.1523/ENEURO.0036-15.2015 · DOI
  17. EM York, 2018, Microglial modulation of neuronal activity in the healthy brain, Dev. Neurobiol, 78, 593, 10.1002/dneu.22571 · DOI · Paper page
  18. SA Wolf, 2017, Microglia in Physiology and Disease, Annu. Rev. Physiol, 79, 619, 10.1146/annurev-physiol-022516-034406 · DOI · Paper page
  19. GJ Harry, 2013, Microglia during development and aging, Pharmacol. Ther, 139, 313, 10.1016/j.pharmthera.2013.04.013 · DOI · Paper page
  20. CN Parkhurst, 2013, Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor, Cell, 155, 1596, 10.1016/j.cell.2013.11.030 · DOI · Paper page
  21. P Yuan, 2016, TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy, Neuron, 90, 724, 10.1016/j.neuron.2016.05.003 · DOI · Paper page
  22. L Ren, 1999, Differential expression of inflammatory mediators in rat microglia cultured from different brain regions, Mol. Brain Res, 65, 198, 10.1016/S0169-328X(99)00016-9 · DOI
  23. A Crotti, 2014, Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors, Nat. Neurosci, 17, 513, 10.1038/nn.3668 · DOI · Paper page
  24. PE Batchelor, 1999, Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor, J. Neurosci, 19, 1708, 10.1523/JNEUROSCI.19-05-01708.1999 · DOI
  25. T Wyss-Coray, 2001, TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice, Nat. Med, 7, 612, 10.1038/87945 · DOI · Paper page
  26. H Lian, 2016, Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer’s Disease, J. Neurosci, 36, 577, 10.1523/JNEUROSCI.2117-15.2016 · DOI · Paper page
  27. X Wang, 2005, Involvement of proinflammatory factors, apoptosis, caspase-3 activation and Ca2+ disturbance in microglia activation-mediated dopaminergic cell degeneration, Mech. Ageing Dev, 126, 1241, 10.1016/j.mad.2005.06.012 · DOI
  28. E. Burda Joshua, 2014, Reactive gliosis and the multicellular response to CNS damage and disease, Neuron, 81, 229, 10.1016/j.neuron.2013.12.034 · DOI
  29. CK Glass, 2010, Mechanisms Underlying Inflammation in Neurodegeneration, Cell, 140, 918, 10.1016/j.cell.2010.02.016 · DOI · Paper page
  30. A Aguzzi, 2013, Microglia: scapegoat, saboteur, or something else?, Science, 339, 156, 10.1126/science.1227901 · DOI · Paper page
  31. RM Ransohoff, 2016, A polarizing question: do M1 and M2 microglia exist?, Nat. Neurosci, 19, 987, 10.1038/nn.4338 · DOI · Paper page
  32. R Brambilla, 2011, Inhibition of soluble tumour necrosis factor encephalomyelitis and promotes axon preservation and remyelination, Brain, 34, 2736, 10.1093/brain/awr199 · DOI
  33. R Li, 2004, Tumor Necrosis Factor Death Receptor Signaling Cascade Is Required for Amyloid- Protein-Induced Neuron Death, J Neurosci, 24, 1760, 10.1523/JNEUROSCI.4580-03.2004 · DOI · Paper page
  34. K Sriram, 2006, Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha, FASEB J, 20, 670, 10.1096/fj.05-5106com · DOI
  35. E Zandi, 1997, The IkB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKa and IKKb, Necessary for IkB Phosphorylation and NF-kB Activation, Cell, 91, 243, 10.1016/S0092-8674(00)80406-7 · DOI
  36. MS Hayden, 2008, Shared Principles in NF-kB Signaling, Cell, 132, 344, 10.1016/j.cell.2008.01.020 · DOI
  37. H Zhong, 2002, The phosphorylation status of nuclear NF-kB determines its association with CBP/p300 or HDAC-1, Mol. Cell, 9, 625, 10.1016/S1097-2765(02)00477-X · DOI
  38. K Grabert, 2016, Microglial brain region − dependent diversity and selective regional sensitivities to aging, Nat Neurosci, 19, 504, 10.1038/nn.4222 · DOI · Paper page
  39. IH Cho, 2008, Role of microglial IKKB in kainic acid-induced hippocampal neuronal cell death, Brain, 131, 3019, 10.1093/brain/awn230 · DOI
  40. BE Clausen, 1999, Conditional gene targeting in macrophages and granulocytes using LysMcre mice, Transgenic Res, 8, 265, 10.1023/A:1008942828960 · DOI · Paper page
  41. EN Burright, 1995, SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat, Cell, 82, 937, 10.1016/0092-8674(95)90273-2 · DOI
  42. S-H Cho, 2015, Neurobiology of Disease SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1b, J Neurosci, 35, 807, 10.1523/JNEUROSCI.2939-14.2015 · DOI · Paper page
  43. A Khoshnan, 2004, Activation of the I B Kinase Complex and Nuclear Factor- B Contributes to Mutant Huntingtin Neurotoxicity, J. Neurosci, 24, 7999, 10.1523/JNEUROSCI.2675-04.2004 · DOI
  44. W Qu, 2017, Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice, J. Neuroinflammation, 14, 1
  45. M Ingram, 2016, Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways, Neuron, 89, 1194, 10.1016/j.neuron.2016.02.011 · DOI
  46. L Duvick, 2010, SCA1-like disease in mice expressing wild-type Ataxin-1 with a serine to aspartic acid replacement at residue 776, Neuron, 67, 929, 10.1016/j.neuron.2010.08.022 · DOI · Paper page
  47. V a. Gennarino, 2015, Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels, Cell, 160, 1087, 10.1016/j.cell.2015.02.012 · DOI
  48. M Cvetanovic, 2011, Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1, Nat. Med, 17, 1445, 10.1038/nm.2494 · DOI
  49. JE Burda, 2014, Reactive gliosis and the multicellular response to CNS damage and disease, Neuron, 81, 229, 10.1016/j.neuron.2013.12.034 · DOI
  50. SA Liddelow, 2017, Neurotoxic reactive astrocytes are induced by activated microglia, Nature, 541, 481, 10.1038/nature21029 · DOI · Paper page
  51. K Hashimoto, 2005, Postnatal development and synapse elimination of climbing fiber to Purkinje cell projection in the cerebellum, Neurosci. Res, 53, 221, 10.1016/j.neures.2005.07.007 · DOI
  52. K Hashimoto, 2009, Translocation of a “‘ Winner ‘” Climbing Fiber to the Purkinje Cell Dendrite and Subsequent Elimination of “‘ Losers ‘” from the Soma in Developing Cerebellum, Neuron, 63, 106, 10.1016/j.neuron.2009.06.008 · DOI
  53. K Hashimoto, 2003, Functional differentiation of multiple climbing fiber inputs during synapse elimination in the developing cerebellum, Neuron, 38, 785, 10.1016/S0896-6273(03)00298-8 · DOI
  54. M Letellier, 2008, Normal adult climbing fiber monoinnervation of cerebellar Purkinje cells in mice lacking MHC class I molecules, Dev. Neurobiol, 68, 997, 10.1002/dneu.20639 · DOI
  55. C Chen, 1995, Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC mutant mice, Cell, 83, 1233, 10.1016/0092-8674(95)90148-5 · DOI
  56. M Paukert, 2014, Norepinephrine controls astroglial responsiveness to local circuit activity, Neuron, 82, 1263, 10.1016/j.neuron.2014.04.038 · DOI · Paper page
  57. B Sensitization, 2016, Microglial TNF- a Suppresses Cocaine-Induced Plasticity and Behavioral Sensitization, Neuron, 90, 1
  58. LM Sedger, 2014, TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants—past, present and future, Cytokine Growth Factor Rev, 25, 453, 10.1016/j.cytogfr.2014.07.016 · DOI
  59. MJ Lee, 2016, IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier, Mol. Neurodegener, 11, 1
  60. MC Arkan, 2005, IKK-beta links inflammation to obesity-induced insulin resistance, Nat. Med, 11, 191, 10.1038/nm1185 · DOI · Paper page
  61. SH Kwon, 2017, Dysfunction of microglial STAT3 alleviates depressive behavior via neuron-microglia interactions, Neuropsychopharmacology, 42, 2072, 10.1038/npp.2017.93 · DOI · Paper page
  62. MJ Lee, 2016, IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier, Mol. Neurodegener, 11, 1
  63. SS Minami, 2014, Progranulin protects against amyloid β deposition and toxicity in Alzheimer’s disease mouse models, Nat. Med, 20, 1157, 10.1038/nm.3672 · DOI · Paper page
  64. B Liao, 2012, Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS, Exp. Neurol, 237, 147, 10.1016/j.expneurol.2012.06.011 · DOI
  65. RD Stowell, 2018, Cerebellar microglia are dynamically unique and survey Purkinje neurons in vivo, Dev. Neurobiol, 1
  66. M Pekny, 2016, Astrocytes: a central element in neurological diseases, Acta Neuropathol, 131, 323, 10.1007/s00401-015-1513-1 · DOI
  67. M V Sofroniew, 2010, Vinters H V. Astrocytes: Biology and pathology, Acta Neuropathol, 119, 7, 10.1007/s00401-009-0619-8 · DOI · Paper page
  68. FR Greten, 2004, IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer, Cell, 118, 285, 10.1016/j.cell.2004.07.013 · DOI · Paper page
  69. Z-W Li, 2003, IKK Is Required for Peripheral B Cell Survival and Proliferation, J. Immunol, 170, 4630, 10.4049/jimmunol.170.9.4630 · DOI
  70. S Mincheva-Tasheva, 2013, NF- B Signaling Pathways: Role in Nervous System Physiology and Pathology, Neuroscientist, 19, 175, 10.1177/1073858412444007 · DOI
  71. J Orthgiess, 2016, Neurons exhibit Lyz2 promoter activity in vivo: Implications for using LysM-Cre mice in myeloid cell research, Eur. J. Immunol, 46, 1529, 10.1002/eji.201546108 · DOI
  72. CL Abram, 2015, Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice, J Immunol Methods, 408, 89, 10.1016/j.jim.2014.05.009 · DOI
  73. M Ye, 2003, Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential, Immunity, 19, 689, 10.1016/S1074-7613(03)00299-1 · DOI
  74. M Cvetanovic, 2011, Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1, Nat Med, 17, 1445, 10.1038/nm.2494 · DOI
  75. M Cvetanovic, 2015, Decreased Expression of Glutamate Transporter GLAST in Bergmann Glia Is Associated with the Loss of Purkinje Neurons in the Spinocerebellar Ataxia Type 1, Cerebellum, 14, 8, 10.1007/s12311-014-0605-0 · DOI

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Metadata

Authors
Ferro, A., Qu, W., Lukowicz, A., Svedberg, D., Johnson, A., & Cvetanovic, M.
Venue
PLOS ONE
Published
2018-07-05
Volume
13
Issue
7
Pages
e0200013
ISSN
1932-6203
Cited by
26
References
10
Language
en

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