Mitophagy: mechanisms, pathophysiological roles, and analysis

Autophagy: Renovation of Cells and Tissues

Mizushima, N., & Komatsu, M. (2011) · Cell · doi:10.1016/j.cell.2011.10.026 · Cited by 6,615

A role for mitochondria in nlrp3 inflammasome activation

Zhou, R., Yazdi, A. S., Menu, P., & Tschopp, J. (2011) · Nature · doi:10.1038/nature09663 · Cited by 5,602

Autophagy: process and functionPreprint

Mizushima, N. (2007) · Genes & Development · doi:10.1101/gad.1599207 · Cited by 4,104

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Lagouge, M., Argmann, C., Gerhart-Hines, Z., Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.11.013 · Cited by 4,057

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Narendra, D., Tanaka, A., Suen, D.-F., & Youle, R. J. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200809125 · Cited by 4,026

Autophagy regulates lipid metabolism

Singh, R., Kaushik, S., Wang, Y., Xiang, Y., Novak, I., Komatsu, M., Tanaka, K., Cuervo, A. M., & Czaja, M. J. (2009) · Nature · doi:10.1038/nature07976 · Cited by 3,975

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J.-I., Tanida, I., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., et al. (2006) · Nature · doi:10.1038/nature04723 · Cited by 3,500

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Nakahira, K., Haspel, J. A., Rathinam, V. A. K., Lee, S.-J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., et al. (2011) · Nature Immunology · doi:10.1038/ni.1980 · Cited by 3,049

Autophagy in adult stem cell homeostasis, aging, and disease therapy

Zhao, K., Chan, I. T. C., Tse, E. H. Y., Xie, Z., Cheung, T. H., & Zeng, Y. A. (2025) · Cell Regeneration · doi:10.1186/s13619-025-00224-2 · Cited by 25

miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury

Yang, J., Do-Umehara, H. C., Zhang, Q., Wang, H., Hou, C., Dong, H., Perez, E. A., Sala, M. A., Anekalla, K. R., Walter, J. M., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.700933 · Cited by 22

IGFBP‐3 functions as a molecular switch that mediates mitochondrial and metabolic homeostasis

Stuard, W. L., Titone, R., & Robertson, D. M. (2021) · The FASEB Journal · doi:10.1096/fj.202100710rr · Cited by 22

Mitophagy Induction and Aryl Hydrocarbon Receptor-Mediated Redox Signaling Contribute to the Suppression of Breast Cancer Cell Growth by Taloxifene via Regulation of Inflammasomes Activation

Tran, V. T.-H., Pham, D., Choi, D., & Park, P. (2022) · Antioxidants and Redox Signaling · doi:10.1089/ars.2021.0192 · Cited by 22

Potential of Microalgae as Functional Foods Applied to Mitochondria Protection and Healthy Aging Promotion

Zanella, L., & Vianello, F. (2023) · Nutraceuticals · doi:10.3390/nutraceuticals3010010 · Cited by 24

Exercise and vascular function in sedentary lifestyles in humans

Fasipe, B., Li, S., & Laher, I. (2023) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-023-02828-6 · Cited by 22

Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection

Adamóski, D., Dias, M. M., Quesñay, J. E. N., Yang, Z., Zagoriy, I., Steyer, A. M., Rodrigues, C. T., Bastos, A. C. S., da Silva, B. N., Costa, R. K. E., et al. (2023) · Nature Structural & Molecular Biology · doi:10.1038/s41594-023-01118-0 · Cited by 22

Favourable metabolic profile sustains mitophagy and prevents metabolic abnormalities in metabolically healthy obese individuals

Bhansali, S., Bhansali, A., & Dhawan, V. (2017) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-017-0298-x · Cited by 22

Mitoimmunity—when mitochondria dictates macrophage function

Corrêa‐da‐Silva, F., Pereira, J. A. D. S., de Aguiar, C. F., & Moraes‐Vieira, P. M. (2017) · Cell Biology International · doi:10.1002/cbin.10921 · Cited by 22

Whole-Transcriptome Analysis of Mouse Models with MPTP-Induced Early Stages of Parkinson’s Disease Reveals Stage-Specific Response of Transcriptome and a Possible Role of Myelin-Linked Genes in Neurodegeneration

Alieva, A. K., Zyrin, V. S., Rudenok, M. M., Kolacheva, A. A., Shulskaya, M. V., Ugryumov, M. V., Slominsky, P. A., & Shadrina, M. I. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-0907-1 · Cited by 22

UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation

Dhar, S. K., Batinic̈‐Haberle, I., & Clair, D. K. S. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.006595 · Cited by 22

Babao Dan attenuates acute ethanol-induced liver injury via Nrf2 activation and autophagy

Yu, Y., Tian, Z., Liang, L., Yang, X. F., Sheng, D., Zeng, J., Li, X., Shi, R., Han, Z., & Wei, L.-X. (2019) · Cell & Bioscience · doi:10.1186/s13578-019-0343-6 · Cited by 22

The mitochondrial metabolic checkpoint in stem cell aging and rejuvenation

Mu, W., Ohkubo, R., Widjaja, A., & Chen, D. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111254 · Cited by 24

A red-emission fluorescent probe for visual monitoring of lysosomal pH changes during mitophagy and cell apoptosis

Wang, X., Fan, L., Zhang, X., Zan, Q., Dong, W., Shuang, S., & Dong, C. (2020) · The Analyst · doi:10.1039/d0an01141j · Cited by 22

Interplay between reactive oxygen species and autophagy in the course of age-related macular degeneration

Nita, M., & Grzybowski, A. E. (2020) · EXCLI journal · doi:10.17179/excli2020-2915 · Cited by 22

A PINK1-mediated mitophagy pathway decides the fate of tumors—to be benign or malignant?

Qian, H., Chao, X., & Ding, W. (2018) · Autophagy · doi:10.1080/15548627.2018.1425057 · Cited by 22

Autophagy and mitochondrial remodelling in mouse mesenchymal stromal cells challenged with Staphylococcus epidermidis

Gorbunov, N. V., McDaniel, D. P., Zhai, M., Liao, P., Garrison, B. R., & Kiang, J. G. (2015) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12518 · Cited by 21

Mitochondrially-Targeted Therapeutic Strategies for Alzheimer’s Disease

Onyango, I. G., Bennett, J. P., & Stokin, G. B. (2021) · Current Alzheimer Research · doi:10.2174/1567205018666211208125855 · Cited by 22

Protection of Quiescence and Longevity of IgG Memory B Cells by Mitochondrial Autophagy

Kodali, S., Li, M., Budai, M. M., Chen, M., & Wang, J. (2022) · The Journal of Immunology · doi:10.4049/jimmunol.2100969 · Cited by 21

Physiological responses to acute hypoxia in the liver of largemouth bass by alteration of mitochondrial function and Ca2+ exchange

Zhao, L., Liao, L., Yan, H., Tang, X. H., He, K., Liu, Q., Luo, J., Du, Z. J., Chen, S. Y., Zhang, X., et al. (2023) · Aquatic Toxicology · doi:10.1016/j.aquatox.2023.106436 · Cited by 21

Tanshinone IIA targeting cell signaling pathways: a plausible paradigm for cancer therapy

Alam, S. S. M., Samanta, A., Uddin, F., Ali, S., & Hoque, M. (2023) · Pharmacological Reports · doi:10.1007/s43440-023-00507-y · Cited by 21

Chlorinated biphenyls effect on estrogen-related receptor expression, steroid secretion, mitochondria ultrastructure but not on mitochondrial membrane potential in Leydig cells

Milon, A., Opydo‐Chanek, M., Tworzydlo, W., Galas, J. F., Pardyak, L., Kamińska, A., Ptak, A., & Kotula‐Balak, M. (2017) · Cell and Tissue Research · doi:10.1007/s00441-017-2596-x · Cited by 21

Constitutive Activation of NAD-Dependent Sirtuin 3 Plays an Important Role in Tumorigenesis of Chromium(VI)-Transformed Cells

Clementino, M., Kim, D., & Zhang, Z. (2019) · Toxicological Sciences · doi:10.1093/toxsci/kfz032 · Cited by 21

Coexisting renal artery stenosis and metabolic syndrome magnifies mitochondrial damage, aggravating poststenotic kidney injury in pigs

Nargesi, A. A., Zhang, L., Tang, H. J., Jordan, K. L., Saadiq, I. M., Textor, S. C., Lerman, L. O., & Eirin, A. (2019) · Journal of Hypertension · doi:10.1097/hjh.0000000000002129 · Cited by 21

Macrophage migration inhibitory factor enhances influenza-associated mortality in mice

Smith, C. A., Tyrrell, D. J., Kulkarni, U., Wood, S. C., Leng, L., Zemans, R. L., Bucala, R., & Goldstein, D. R. (2019) · JCI Insight · doi:10.1172/jci.insight.128034 · Cited by 21

Targeting the PINK1/Parkin pathway: A new perspective in the prevention and therapy of diabetic retinopathy

D’Amico, A. G., Maugeri, G., Magrì, B., Bucolo, C., & D’Agata, V. (2024) · Experimental Eye Research · doi:10.1016/j.exer.2024.110024 · Cited by 22

Understanding the autophagic functions in cancer stem cell maintenance and therapy resistance

Niharika, N., & Garg, M. (2024) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2024.23 · Cited by 23

Pre-Implantation Mouse Embryos Cultured In Vitro under Different Oxygen Concentrations Show Altered Ultrastructures

Belli, M., Rinaudo, P. F., Palmerini, M. G., Ruggeri, E., Antonouli, S., Nottola, S. A., & Macchiarelli, G. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17103384 · Cited by 20

Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy

Lu, Y., Li, L., Chen, H., Jing, X., Wang, M., Ge, L., Yang, J., Zhang, M., & Tang, X. (2021) · OncoTargets and Therapy · doi:10.2147/ott.s284182 · Cited by 20

Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney

Wu, Y., Yang, F., Zhou, G., Wang, Q., Xing, C., Bai, H., Yi, X., Xiong, Z., Yang, S., & Cao, H. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.842259 · Cited by 20

Assessment of Mitochondrial Function and Oxygen Consumption Measured During Ex Vivo Normothermic Machine Perfusion of Injured Pig Kidneys Helps to Monitor Organ Viability

Hunter, J. P., Faro, M. L. L., Rozenberg, K. M., Dengu, F., Ogbemudia, A. E., Weißenbacher, A., Mulvey, J. F., Knijff, L. W. D., Gopalakrishnan, K., & Ploeg, R. J. (2022) · Transplant International · doi:10.3389/ti.2022.10420 · Cited by 20

Mitochondria and Endoplasmic Reticulum Stress in Retinal Organoids from Patients with Vision Loss

Lee, E.-J., Diaz‐Aguilar, M. S., Min, H., Choi, J., Duran, D. A. V., Grandjean, J. M. D., Wiseman, R. L., Kroeger, H., & Lin, J. H. (2022) · American Journal Of Pathology · doi:10.1016/j.ajpath.2022.12.002 · Cited by 21

Impaired Mitochondrial Function in T-Lymphocytes as a Result of Exposure to HIV and ART

Blagov, A. V., Sukhorukov, V. N., Guo, S., Zhang, D., Popov, M. A., & Orekhov, A. N. (2023) · Cells · doi:10.3390/cells12071072 · Cited by 20

Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntington’s Disease Striatal Cells

Kamitsuka, P. J., Ghanem, M. M., Ziar, R., McDonald, S. E., Thomas, M. G., & Kwakye, G. F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087178 · Cited by 20

Yi Mai granule improve energy supply of endothelial cells in atherosclerosis via miRNA-125a-5p regulating mitochondrial autophagy through Pink1-Mfn2-Parkin pathway

Kong, D. Z., Sun, P., Lu, Y., Yang, Y., Min, D. Y., Zheng, S. C., Yang, G. L., Zhang, Z., Yang, G. L., & Jiang, J. W. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.117114 · Cited by 20

Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics

Gumeni, S., Evangelakou, Z., Tsakiri, E. N., Scorrano, L., & Trougakos, I. P. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101219 · Cited by 21

Effects of Plant and Animal Natural Products on Mitophagy

Shakeri, F., Bianconi, V., Pirro, M., & Sahebkar, A. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/6969402 · Cited by 20

A Glimmer of Hope: Maintain Mitochondrial Homeostasis to Mitigate Alzheimer’s Disease

Li, W., Kui, L., Tsirukis, D. I., Gong, X., & Tang, M. (2020) · Aging and Disease · doi:10.14336/ad.2020.0105 · Cited by 21

Pivotal role of endothelial cell autophagy in sepsis

Li, Y., Suo, L., Fu, Z., Li, G., & Zhang, J. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119413 · Cited by 20

Active autophagy in cancer‐associated fibroblasts: Recent advances in understanding the novel mechanism of tumor progression and therapeutic response

Jena, B. C., Rout, L., Dey, A., & Mandal, M. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30419 · Cited by 20

Effects of exercise in a cold environment on gene expression for mitochondrial biogenesis and mitophagy

Opichka, M. A., Shute, R. J., Marshall, K., & Slivka, D. R. (2019) · Cryobiology · doi:10.1016/j.cryobiol.2019.08.007 · Cited by 19

The “Self-eating” of cancer-associated fibroblast: A potential target for cancer

Chen, Y., Zhang, X., Yang, H., Liang, T., & Bai, X. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114762 · Cited by 20

The mediating role of inflammaging between mitochondrial dysfunction and sarcopenia in aging: a review.

Xu, X., & Wen, Z. (2023) · PubMed Central · Cited by 21

Dysfunctional mitochondria elicit bioenergetic decline in the aged heart

Mone, P., Agyapong, E. D., Morciano, G., Jankauskas, S. S., Luca, A. D., Varzideh, F., Pinton, P., & Santulli, G. (2024) · The Journal of Cardiovascular Aging · doi:10.20517/jca.2023.50 · Cited by 19

Hepatitis C virus, mitochondria and auto/mitophagy: Exploiting a host defense mechanism

Ruggieri, V. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i10.2624 · Cited by 20

A Bird’s-Eye View of the Multiple Biochemical Mechanisms that Propel Pathology of Alzheimer’s Disease: Recent Advances and Mechanistic Perspectives on How to Halt the Disease Progression Targeting Multiple Pathways

Vegh, C., Stokes, K., Ma, D., Wear, D., Cohen, J. S., Ray, S. D., & Pandey, S. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-181230 · Cited by 19

Insulin receptor preserves mitochondrial function by binding VDAC1 in insulin insensitive mucosal epithelial cells

Titone, R., & Robertson, D. M. (2019) · The FASEB Journal · doi:10.1096/fj.201901316rr · Cited by 19

Cells deficient for Krüppel-like factor 4 exhibit mitochondrial dysfunction and impaired mitophagy

Rosencrans, W. M., Walsh, Z. H., Houerbi, N., Blum, A., Belew, M. D., Liu, C., Chernak, B. J., Brauer, P. R., Trazo, T. A. A., Olson, A., et al. (2019) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2019.151061 · Cited by 19

Fundc1 is necessary for proper body axis formation during embryogenesis in zebrafish

Xu, G., Shen, H., Nibona, E., Wu, K., Ke, X., Hafiz, M. A. A., Liang, X., Zhong, X., Zhou, Q., Qi, C., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-55415-0 · Cited by 19

Pathophysiology of Conversion to Symptomatic Leber Hereditary Optic Neuropathy and Therapeutic Implications: a Review

Mejia-Vergara, A. J., Seleme, N., Sadun, A. A., & Karanjia, R. (2020) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-020-01032-8 · Cited by 19

Fucoidan Oligosaccharide Supplementation Relieved Kidney Injury and Modulated Intestinal Homeostasis in D-Galactose-Exposed Rats

Shi, J., Xu, Y., Zhang, K., Liu, Y., Zhang, N., Zhang, Y., Zhang, H., Liang, X., & Xue, M. (2025) · Nutrients · doi:10.3390/nu17020325 · Cited by 18

Serum DJ-1 Is a Biomarker of Colorectal Cancer and DJ-1 Activates Mitophagy to Promote Colorectal Cancer Progression

Chen, W. T., Yang, H.-B., Ke, T., Liao, W., & Hung, S. (2021) · Cancers · doi:10.3390/cancers13164151 · Cited by 18

Serotonin regulation of mitochondria in kidney diseases

Hurtado, K. A., Scholpa, N. E., Schnellmann, J. G., & Schnellmann, R. G. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107154 · Cited by 18

Targeting apoptosis in clear cell renal cell carcinoma

Kowalewski, A., Borowczak, J., Maniewski, M., Gostomczyk, K., Grzanka, D., & Szylberg, Ł. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116805 · Cited by 18

Cytarabine prevents neuronal damage by enhancing AMPK to stimulate PINK1 / Parkin-involved mitophagy in Parkinson's disease model

Li, L., Zhang, Y., Chen, Z., Xu, C., Xu, Z., Pei, H., Wang, W., Yao, R., & Hao, C. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176743 · Cited by 18

Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting BNIP3, autophagy, and mitochondria with low doses of valproic acid and vincristine

Cavaliere, V., Lombardo, T., Costantino, S. N., Kornblihtt, L. I., Álvarez, É., & Blanco, G. A. C. (2014) · European Journal of Cancer · doi:10.1016/j.ejca.2014.09.012 · Cited by 18

Interactions between mitochondrial and nuclear DNA in mammalian cells are non-random

Doynova, M., Berretta, A., Jones, M. B., Jasoni, C. L., Vickers, M. H., & O'Sullivan, J. M. (2016) · Mitochondrion · doi:10.1016/j.mito.2016.08.003 · Cited by 18

Effect of a trans fatty acid-enriched diet on mitochondrial, inflammatory, and oxidative stress parameters in the cortex and hippocampus of Wistar rats

Longhi, R., Almeida, R. F., Pettenuzzo, L. F., de Souza, D. G., Machado, L. D. S., Quincozes‐Santos, A., & Souza, D. O. (2017) · European Journal of Nutrition · doi:10.1007/s00394-017-1474-3 · Cited by 18

Impact of intravenous iron on cardiac and skeletal oxidative stress and cardiac mitochondrial function in experimental uraemia chronic kidney disease

Bhandari, S. (2021) · Frontiers in Bioscience-Landmark · doi:10.52586/4958 · Cited by 18

Cdk8 Kinase Module: A Mediator of Life and Death Decisions in Times of Stress

Friedson, B., & Cooper, K. F. (2021) · Microorganisms · doi:10.3390/microorganisms9102152 · Cited by 19

Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of view

Raee, P., Tan, S. C., Najafi, S., Zandsalimi, F., Low, T. Y., Aghamiri, S., Fazeli, E., Aghapour, M., Mofarahe, Z. S., Heidari, M. H., et al. (2023) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-023-01134-1 · Cited by 18

Protein half‐life determines expression of proteostatic networks in podocyte differentiation

Schroeter, C. B., Koehler, S., Kann, M., Schermer, B., Benzing, T. R., Brinkkoetter, P. T., & Rinschen, M. M. (2018) · The FASEB Journal · doi:10.1096/fj.201701307r · Cited by 18

Drp-1 as Potential Therapeutic Target for Lipopolysaccharide-Induced Vascular Hyperpermeability

Luo, X., Cai, S., Li, Y., Li, G., Cao, Y., Ai, C., Gao, Y., & Li, T. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/5820245 · Cited by 18

HIVAN associated tubular pathology with reference to ER stress, mitochondrial changes, and autophagy

Katuri, A., Bryant, J., Patel, D. A., Patel, V. P., Andhavarapu, S., Asemu, G., Davis, H., & Makar, T. K. (2018) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2018.12.009 · Cited by 17

Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice

Sakai, T., Takagaki, H., Yamagiwa, N., Ui, M., Hatta, S., & Imai, J. (2021) · Antioxidants · doi:10.3390/antiox10091398 · Cited by 17

Sirtuins and Sepsis: Cross Talk between Redox and Epigenetic Pathways

Anugraha, G., Roychowdhury, S., & Vachharajani, V. (2021) · Antioxidants · doi:10.3390/antiox11010003 · Cited by 17

Sestrin 2 Deficiency Exacerbates Noise-Induced Cochlear Injury Through Inhibiting ULK1/Parkin-Mediated Mitophagy

Li, Y., Li, S., Wu, L., Wu, T., Li, M., Du, D., Chen, Y., Wang, C., Li, X., Zhang, S., et al. (2022) · Antioxidants and Redox Signaling · doi:10.1089/ars.2021.0283 · Cited by 17

Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats

Hao, J., Xi, Y., Jiao, L., Wen, X., Wu, R., Chang, G., Sun, F., Wei, C., & Li, H. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110465 · Cited by 17

MORN4 protects cardiomyocytes against ischemic injury via MFN2-mediated mitochondrial dynamics and mitophagy

Zhou, J., Liu, H., Zhang, T., Wang, Z., Zhang, J., Lu, Y., Li, Z., Kong, W., & Zhao, J. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.01.016 · Cited by 17

Fish Models for Exploring Mitochondrial Dysfunction Affecting Neurodegenerative Disorders

Otsuka, T., & Matsui, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087079 · Cited by 17

Antioxidative Role of Heterophagy, Autophagy, and Mitophagy in the Retina and Their Association with the Age-Related Macular Degeneration (AMD) Etiopathogenesis

Nita, M., & Grzybowski, A. E. (2023) · Antioxidants · doi:10.3390/antiox12071368 · Cited by 19

Icariin prevents depression-like behaviors in chronic unpredictable mild stress-induced rats through Bax/cytoplasm C/caspase-3 axis to alleviate neuronal apoptosis

Wu, X., Zhang, X., Sun, L., Lu, X., & Shen, C. (2023) · Cellular and Molecular Biology · doi:10.14715/cmb/2023.69.7.32 · Cited by 17

The movement of mitochondria in breast cancer: internal motility and intercellular transfer of mitochondria

Libring, S., Berestesky, E. D., & Reinhart‐King, C. A. (2024) · Clinical & Experimental Metastasis · doi:10.1007/s10585-024-10269-3 · Cited by 17

Placental mitochondrial impairment and its association with maternal metabolic dysfunction

Grismaldo, A., Luévano‐Martínez, L. A., Reyes, M., García-Márquez, G. G., García‐Rivas, G., & Sobrevía, L. (2024) · The Journal of Physiology · doi:10.1113/jp285935 · Cited by 19

Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling

Ye, G., Sun, X., Li, J., Pu, M., & Zhang, J. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2024.12.045 · Cited by 17

Common Traits Spark the Mitophagy/Xenophagy Interplay

Singh, A., Kendall, S. L., & Campanella, M. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01172 · Cited by 17

Effects of Mitophagy on Regulatory T Cell Function in Patients With Myasthenia Gravis

Wang, N., Jiang, Y., Karim, M. R., Zhong, P., Sun, Y.-P., Zhang, H.-Y., & Wang, Y.-F. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00238 · Cited by 17

Melatonin ameliorates murine fetal oocyte meiotic dysfunction in F1 and F2 offspring caused by nicotine exposure during pregnancy

Liu, W., Tan, S., Wang, Y., Li, L., Sun, X.-F., Liu, J., Klinger, F. G., Felici, M. D., Shen, W., & Cheng, S. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114519 · Cited by 17

Protein homeostasis in LGMDR9 (LGMD2I) – The role of ubiquitin–proteasome and autophagy–lysosomal system

Franekova, V., Storjord, H. I., Leivseth, G., & Nilssen, Ø. (2020) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12684 · Cited by 18

Polygoni Multiflori Radix Preparat Delays Skin Aging by Inducing Mitophagy

Liu, X., Yang, C., Deng, Y., Liu, P., Yang, H., Du, X., & Du, Y. (2021) · BioMed Research International · doi:10.1155/2021/5847153 · Cited by 17

Monitoring Mitophagy in Mammalian Cells

Chen, L., Ma, K., Han, J., Chen, Q., & Zhu, Y. (2016) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2016.10.038 · Cited by 17

Effect of environmental stresses during fermentation on brewing yeast and exploration on the novel flocculation-associated function of RIM15 gene

Hou, D., Xu, X., Wang, J., Liu, C., Niu, C., Zheng, F., & Li, Q. (2023) · Bioresource Technology · doi:10.1016/j.biortech.2023.129004 · Cited by 17

Ultrafast labeling and high-fidelity imaging of mitochondria in cancer cells using an aggregation-enhanced emission fluorescent probe

Liu, L., Zou, Q., Leung, J., Wang, J., Kam, C., Chen, S., Feng, S., & Wu, M. (2019) · Chemical Communications · doi:10.1039/c9cc07775h · Cited by 17

Perspectives of mitochondria-lysosome-related organelle in hepatocyte dedifferentiation and implications in chronic liver disease

Ma, X., Ni, H., & Ding, W. (2024) · eGastroenterology · doi:10.1136/egastro-2023-100046 · Cited by 17

Spermidine Supplementation Protects the Liver Endothelium from Liver Damage in Mice

Campreciós, G., Ruart, M., Anton, A., Suárez-Herrera, N., Montironi, C., Martínez–Sánchez, C., Jiménez, N., Lafoz, E., García‐Calderó, H., Vilaseca, M., et al. (2021) · Nutrients · doi:10.3390/nu13113700 · Cited by 16

Double-Edged Sword: Exploring the Mitochondria–Complement Bidirectional Connection in Cellular Response and Disease

Lin, J., Hwang, S., Luo, H., & Mohamud, Y. (2024) · Biology · doi:10.3390/biology13060431 · Cited by 16

Role of mitochondrial homeostasis in D-galactose-induced cardiovascular ageing from bench to bedside

Sahu, Y., Jamadade, P., Maharana, K. C., & Singh, S. (2024) · Mitochondrion · doi:10.1016/j.mito.2024.101923 · Cited by 16

Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation

Isei, M. O., Crockett, M., Chen, E., Rodwell‐Bullock, J., Carroll, T., Girardi, P., Nehrke, K. W., & Johnson, G. V. W. (2025) · PLoS ONE · doi:10.1371/journal.pone.0307358 · Cited by 16

Anesthesia with Disuse Leads to Autophagy Up-regulation in the Skeletal Muscle

Kashiwagi, A., Hosokawa, S., Maeyama, Y., Ueki, R., Kaneki, M., Martyn, J. A. J., & Yasuhara, S. (2014) · Anesthesiology · doi:10.1097/aln.0000000000000561 · Cited by 16

Approaches to Investigating the Protein Interactome of PTEN

Smith, S. L., Pitt, A. R., & Spickett, C. M. (2020) · Journal of Proteome Research · doi:10.1021/acs.jproteome.0c00570 · Cited by 16

A matrix targeted fluorescent probe to monitor mitochondrial dynamics

Ramesh, M., Rajasekhar, K., Gupta, K., Babagond, V., Saini, D. K., & Govindaraju, T. (2020) · Organic & Biomolecular Chemistry · doi:10.1039/d0ob02128h · Cited by 16

Pathophysiological Aspects of the Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations

Summerhill, V. I., Sukhorukov, V. N., Eid, A. H., Недосугова, Л. В., Sobenin, I. A., & Orekhov, A. N. (2021) · BioMolecular Concepts · doi:10.1515/bmc-2021-0007 · Cited by 17

A multimodal fluorescent probe for portable colorimetric detection of pH and it’s application in mitochondrial bioimaging

Luo, W., Shuan, Z., Ye, J., Jiang, B., Meng, Q., Zhang, G., Li, J., & Tang, Y. (2021) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2021.120554 · Cited by 16

pH-responsive aldehyde-bearing cyclometalated iridium(III) complex for tracking intracellular pH fluctuations under external stimulation

Qian, M., Zhang, D., Qi, H., Yang, X., Yin, G., Zhang, C., Guo, J., & Qi, H. (2022) · Chinese Chemical Letters · doi:10.1016/j.cclet.2022.03.059 · Cited by 16

Age-related Mitochondrial Dysfunction in Parkinson's Disease: New Insights Into the Disease Pathology

Rani, L., Sahu, M. R., & Mondal, A. C. (2022) · Neuroscience · doi:10.1016/j.neuroscience.2022.07.007 · Cited by 16

Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers

Li, C., White-Springer, S. H., Warren, L. K., & Wohlgemuth, S. E. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.11.022 · Cited by 16

p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation

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Genetic Ablation of Calcium-independent Phospholipase A2γ Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice

Elimam, H., Papillon, J., Guillemette, J., Navarro‐Betancourt, J. R., & Cybulsky, A. V. (2019) · Scientific Reports · doi:10.1038/s41598-019-52834-x · Cited by 16

Mitochondrial Oxidative Stress and Vascular Remodeling in Uric Acid Nephropathy: Mechanistic Insights and Therapeutic Implications

Liang, J., Qiu, Y., Fu, T., Li, J., Xiao, F., Xing, G., Cai, H., & Tong, Y. (2025) · International Journal of Nephrology and Renovascular Disease · doi:10.2147/ijnrd.s549209 · Cited by 15

Emendation of autophagic dysfuction in neurological disorders: a potential therapeutic target

Sainani, S. R., Pansare, P. A., Rode, K., Bhalchim, V. M., Doke, R. R., & Desai, S. M. (2020) · International Journal of Neuroscience · doi:10.1080/00207454.2020.1822356 · Cited by 16

Mitophagy: A Complex Mechanism of Mitochondrial Removal

Novak, I. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4407 · Cited by 213

Induction and Detection of Mitophagy

Yapryntseva, M. A., Zhivotovsky, B., & Gogvadze, V. G. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2071-7_14 · Cited by 5

Mitophagy

Mijaljica, D., Prescott, M., & Devenish, R. J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405528-5.00005-5 · Cited by 3

Mitochondria removal by autophagy

Wang, K., & Klionsky, D. J. (2011) · Autophagy · doi:10.4161/auto.7.3.14502 · Cited by 380

Editorial: Mitophagy in health and disease, volume II

Fang, E. F., Tavernarakis, N., & Palikaras, K. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1242664