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Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

Sompol, Pradoldej, Furman, Jennifer L., Pleiss, Melanie M., Kraner, Susan D., Artiushin, Irina A., Batten, Seth R., Quintero, Jorge E., Simmerman, Linda A., Beckett, Tina L., Lovell, Mark A., Murphy, M. Paul, Gerhardt, Greg A., Norris, Christopher M.·2017·The Journal of Neuroscience

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Crossref · 10.1523/jneurosci.0877-17.2017

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  1. Abdul HM, Sama MA, Furman JL, Mathis DM, Beckett TL, Weidner AM, Patel ES, Baig I, Murphy MP, LeVine H 3rd, Kraner SD, Norris CM (2009) Cognitive decline in Alzheimer's disease is associated with selec- tive changes in calcineurin/NFAT signaling. J Neurosci 29:12957-12969. CrossRef Medline · DOI
  2. Aida T, Ito Y, Takahashi YK, Tanaka K (2012) Overstimulation of NMDA receptors impairs early brain development in vivo. PLoS One 7:e36853. CrossRef Medline · DOI
  3. Andreasson KI, Bachstetter AD, Colonna M, Ginhoux F, Holmes C, Lamb B, Landreth G, Lee DC, Low D, Lynch MA, Monsonego A, O'Banion MK, Pekny M, Puschmann T, Russek-Blum N, Sandusky LA, Selenica ML, Takata K, Teeling J, Town T, et al (2016) Targeting innate immunity for neurodegenerative disorders of the central nervous system. J Neurochem 138:653-693. CrossRef Medline · DOI · Paper page
  4. Audrain M, Fol R, Dutar P, Potier B, Billard JM, Flament J, Alves S, Burlot MA, Dufayet-Chaffaud G, Bemelmans AP, Valette J, Hantraye P, De ´glon N, Cartier N, Braudeau J (2016) Alzheimer's disease-like APP process- ing in wild-type mice identifies synaptic defects as initial steps of disease progression. Mol Neurodegener 11:5. CrossRef Medline · DOI
  5. Bachstetter AD, Norris CM, Sompol P, Wilcock DM, Goulding D, Neltner JH, St Clair D, Watterson DM, Van Eldik LJ (2012) Early stage drug treatment that normalizes proinflammatory cytokine production attenu- ates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology. J Neurosci 32: 10201-10210. CrossRef Medline · DOI
  6. Bakker A, Krauss GL, Albert MS, Speck CL, Jones LR, Stark CE, Yassa MA, Bassett SS, Shelton AL, Gallagher M (2012) Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron 74:467-474. CrossRef Medline · DOI
  7. Bomben V, Holth J, Reed J, Cramer P, Landreth G, Noebels J (2014) Bex- arotene reduces network excitability in models of Alzheimer's disease and epilepsy. Neurobiol Aging 35:2091-2095. CrossRef Medline · DOI
  8. Bouvier DS, Murai KK (2015) Synergistic actions of microglia and astro- cytes in the progression of Alzheimer's disease. J Alzheimers Dis 45:1001- 1014. CrossRef Medline · DOI
  9. Busche MA, Eichhoff G, Adelsberger H, Abramowski D, Wiederhold KH, Haass C, Staufenbiel M, Konnerth A, Garaschuk O (2008) Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzhei- mer's disease. Science 321:1686 -1689. CrossRef Medline · DOI · Paper page
  10. Busche MA, Konnerth A (2015) Neuronal hyperactivity-a key defect in Alzheimer's disease? Bioessays 37:624 -632. CrossRef Medline · DOI · Paper page
  11. Dallas M, Boycott HE, Atkinson L, Miller A, Boyle JP, Pearson HA, Peers C (2007) Hypoxia suppresses glutamate transport in astrocytes. J Neurosci 27:3946 -3955. CrossRef Medline · DOI
  12. Fernandez AM, Fernandez S, Carrero P, Garcia-Garcia M, Torres-Aleman I (2007) Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals. J Neurosci 27: 8745-8756. CrossRef Medline · DOI · Paper page
  13. Fontana R, Agostini M, Murana E, Mahmud M, Scremin E, Rubega M, Spara- cino G, Vassanelli S, Fasolato C (2017) Early hippocampal hyperexcit- ability in PS2APP mice: role of mutant PS2 and APP. Neurobiol Aging 50:64 -76. CrossRef Medline · DOI
  14. Furman JL, Norris CM (2014) Calcineurin and glial signaling: neuroinflam- mation and beyond. J Neuroinflammation 11:158. CrossRef Medline · DOI
  15. Furman JL, Sama DM, Gant JC, Beckett TL, Murphy MP, Bachstetter AD, Van Eldik LJ, Norris CM (2012) Targeting astrocytes ameliorates neu- rologic changes in a mouse model of Alzheimer's disease. J Neurosci 32:16129 -16140. CrossRef Medline · DOI · Paper page
  16. Furman JL, Sompol P, Kraner SD, Pleiss MM, Putman EJ, Dunkerson J, Mohmmad Abdul H, Roberts KN, Scheff SW, Norris CM (2016) Block- ade of astrocytic calcineurin/NFAT signaling helps to normalize hip- pocampal synaptic function and plasticity in a rat model of traumatic brain injury. J Neurosci 36:1502-1515. CrossRef Medline · DOI
  17. Gong HY, Zheng F, Zhang C, Chen XY, Liu JJ, Yue XQ (2016) Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway. Int J Mol Med 38:943-950. CrossRef Medline · DOI
  18. Gray BC, Skipp P, O'Connor VM, Perry VH (2006) Increased expression of glial fibrillary acidic protein fragments and mu-calpain activation within the hippocampus of prion-infected mice. Biochem Soc Trans 34:51-54. CrossRef Medline · DOI
  19. Grienberger C, Rochefort NL, Adelsberger H, Henning HA, Hill DN, Reich- wald J, Staufenbiel M, Konnerth A (2012) Staged decline of neuronal function in vivo in an animal model of Alzheimer's disease. Nat Commun 3:774. CrossRef Medline · DOI
  20. Harvey BK, Airavaara M, Hinzman J, Wires EM, Chiocco MJ, Howard DB, Shen H, Gerhardt G, Hoffer BJ, Wang Y (2011) Targeted over-expression of glu- tamate transporter 1 (GLT-1) reduces ischemic brain injury in a rat model of stroke. PLoS One 6:e22135. CrossRef Medline · DOI
  21. Hasbani MJ, Hyrc KL, Faddis BT, Romano C, Goldberg MP (1998) Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery. Exp Neurol 154:241-258. CrossRef Medline · DOI
  22. Hascup KN, Hascup ER, Stephens ML, Glaser PE, Yoshitake T, Mathe ´AA, Gerhardt GA, Kehr J (2011) Resting glutamate levels and rapid gluta- mate transients in the prefrontal cortex of the Flinders Sensitive Line rat: a genetic rodent model of depression. Neuropsychopharmacology 36: 1769 -1777. CrossRef Medline · DOI
  23. Hefendehl JK, LeDue J, Ko RW, Mahler J, Murphy TH, MacVicar BA (2016) Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Abeta plaques by iGluSnFR two-photon imaging. Nat Com- mun 7:13441. CrossRef Medline · DOI
  24. Hinzman JM, Thomas TC, Quintero JE, Gerhardt GA, Lifshitz J (2012) Dis- ruptions in the regulation of extracellular glutamate by neurons and glia in the rat striatum two days after diffuse brain injury. J Neurotrauma 29:1197-1208. CrossRef Medline · DOI
  25. Huang W, Fileta JB, Dobberfuhl A, Filippopolous T, Guo Y, Kwon G, Grosskreutz CL (2005) Calcineurin cleavage is triggered by elevated in- traocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma. Proc Natl Acad Sci U S A 102:12242- 12247. CrossRef Medline · DOI
  26. Huang YH, Bergles DE (2004) Glutamate transporters bring competition to the synapse. Curr Opin Neurobiol 14:346 -352. CrossRef Medline · DOI
  27. Hudry E, Wu HY, Arbel-Ornath M, Hashimoto T, Matsouaka R, Fan Z, Spires-Jones TL, Betensky RA, Bacskai BJ, Hyman BT (2012) Inhibition of the NFAT pathway alleviates amyloid ␤ neurotoxicity in a mouse model of Alzheimer's disease. J Neurosci 32:3176 -3192. CrossRef Medline · DOI
  28. Hunsberger HC, Rudy CC, Batten SR, Gerhardt GA, Reed MN (2015) P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway. J Neurochem 132:169 -182. CrossRef Medline · DOI
  29. Isaac JT, Nicoll RA, Malenka RC (1995) Evidence for silent synapses: impli- cations for the expression of LTP. Neuron 15:427-434. CrossRef Medline · DOI · Paper page
  30. Karklin Fontana AC, Fox DP, Zoubroulis A, Valente Mortensen O, Raghu- pathi R (2016) Neuroprotective effects of the glutamate transporter ac- tivator (R)-(-)-5-methyl-1-nicotinoyl-2-pyrazoline (MS-153) following traumatic brain injury in the adult rat. J Neurotrauma 33:1073-1083. CrossRef Medline · DOI
  31. Kellner V, Menkes-Caspi N, Beker S, Stern EA (2014) Amyloid-beta alters ongoing neuronal activity and excitability in the frontal cortex. Neurobiol Aging 35:1982-1991. CrossRef Medline · DOI
  32. Kim JH, Kwon SJ, Stankewich MC, Huh GY, Glantz SB, Morrow JS (2016) Reactive protoplasmic and fibrous astrocytes contain high levels of calpain-cleaved alpha 2 spectrin. Exp Mol Pathol 100:1-7. CrossRef Medline · DOI
  33. Kim SY, Chao W, Choi SY, Volsky DJ (2003) Cloning and characterization of the 3Ј-untranslated region of the human excitatory amino acid trans- porter 2 transcript. J Neurochem 86:1458 -1467. CrossRef Medline · DOI
  34. Kuchibhotla KV, Lattarulo CR, Hyman BT, Bacskai BJ (2009) Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 323:1211-1215. CrossRef Medline · DOI · Paper page
  35. Lacey CJ, Bryant A, Brill J, Huguenard JR (2012) Enhanced NMDA receptor-dependent thalamic excitation and network oscillations in star- gazer mice. J Neurosci 32:11067-11081. CrossRef Medline · DOI
  36. Liu F, Grundke-Iqbal I, Iqbal K, Oda Y, Tomizawa K, Gong CX (2005) Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J Biol Chem 280:37755-37762. CrossRef Medline · DOI
  37. Mallolas J, Hurtado O, Castellanos M, Blanco M, Sobrino T, Serena J, Vivan- cos J, Castillo J, Lizasoain I, Moro MA, Da ´valos A (2006) A polymor- phism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke. J Exp Med 203:711-717. CrossRef Medline · DOI
  38. Malm TM, Jay TR, Landreth GE (2015) The evolving biology of microglia in Alzheimer's disease. Neurotherapeutics 12:81-93. CrossRef Medline · DOI · Paper page
  39. Maragakis NJ, Rothstein JD (2006) Mechanisms of disease: astrocytes in neurodegenerative disease. Nat Clin Pract Neurol 2:679 -689. CrossRef Medline · DOI
  40. Masliah E, Alford M, Mallory M, Rockenstein E, Moechars D, Van Leuven F (2000) Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice. Exp Neurol 163:381-387. CrossRef Medline · DOI
  41. Mathis DM, Furman JL, Norris CM (2011) Preparation of acute hippocam- pal slices from rats and transgenic mice for the study of synaptic altera- tions during aging and amyloid pathology. J Vis Exp (49):e2330. CrossRef Medline · DOI
  42. Matveeva EA, Davis VA, Whiteheart SW, Vanaman TC, Gerhardt GA, Slevin JT (2012) Kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes correlates with enhanced glutamate release. Epilep- sia 53:157-167. CrossRef Medline · DOI
  43. Meeker KD, Meabon JS, Cook DG (2015) Partial loss of the glutamate trans- porter GLT-1 alters brain Akt and insulin signaling in a mouse model of Alzheimer's disease. J Alzheimers Dis 45:509 -520. CrossRef Medline · DOI
  44. Miller EM, Pomerleau F, Huettl P, Gerhardt GA, Glaser PE (2014) Aberrant glutamate signaling in the prefrontal cortex and striatum of the sponta- neously hypertensive rat model of attention-deficit/hyperactivity disor- der. Psychopharmacology (Berl) 231:3019 -3029. CrossRef Medline · DOI
  45. Miller EM, Quintero JE, Pomerleau F, Huettl P, Gerhardt GA, Glaser PE (2015) Simultaneous glutamate recordings in the frontal cortex network with multisite biomorphic microelectrodes: new tools for ADHD re- search. J Neurosci Methods 252:75-79. CrossRef Medline · DOI
  46. Minkeviciene R, Rheims S, Dobszay MB, Zilberter M, Hartikainen J, Fu ¨lo ¨p L, Penke B, Zilberter Y, Harkany T, Pitka ¨nen A, Tanila H (2009) Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci 29:3453-3462. CrossRef Medline · DOI
  47. Mohmmad Abdul H, Baig I, Levine H 3rd, Guttmann RP, Norris CM (2011) Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in pri- mary cell culture. Aging Cell 10:103-113. CrossRef Medline · DOI
  48. Moidunny S, Matos M, Wesseling E, Banerjee S, Volsky DJ, Cunha RA, Ag- ostinho P, Boddeke HW, Roy S (2016) Oncostatin M promotes excito- toxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicity. J Neuroinflammation 13:144. CrossRef Medline · DOI
  49. Mookherjee P, Green PS, Watson GS, Marques MA, Tanaka K, Meeker KD, Meabon JS, Li N, Zhu P, Olson VG, Cook DG (2011) GLT-1 loss accel- erates cognitive deficit onset in an Alzheimer's disease animal model. J Alzheimers Dis 26:447-455. CrossRef Medline · DOI
  50. Murphy MP, Beckett TL, Ding Q, Patel E, Markesbery WR, St Clair DK, LeVine H 3rd, Keller JN (2007) Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice. Neurobiol Dis 27:301- 311. CrossRef Medline · DOI
  51. Nagamoto-Combs K, Combs CK (2010) Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells). J Neurosci 30:9641-9646. CrossRef Medline · DOI
  52. Noebels J (2011) A perfect storm: converging paths of epilepsy and Alzhei- mer's dementia intersect in the hippocampal formation. Epilepsia 52 [Suppl 1]:39 -46. CrossRef Medline · DOI
  53. Norris CM, Scheff SW (2009) Recovery of afferent function and synaptic strength in hippocampal CA1 following traumatic brain injury. J Neu- rotrauma 26:2269 -2278. CrossRef Medline · DOI
  54. Norris CM, Kadish I, Blalock EM, Chen KC, Thibault V, Porter NM, Land- field PW, Kraner SD (2005) Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's mod- els. J Neurosci 25:4649 -4658. CrossRef Medline · DOI · Paper page
  55. Norris CM, Blalock EM, Thibault O, Brewer LD, Clodfelter GV, Porter NM, Landfield PW (2006) Electrophysiological mechanisms of delayed excito- toxicity: positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release. J Neurophysiol 96:2488 - 2500. CrossRef Medline · DOI
  56. Norris CM, Sompol P, Roberts KN, Ansari M, Scheff SW (2016) Pycnogenol protects CA3-CA1 synaptic function in a rat model of traumatic brain injury. Exp Neurol 276:5-12. CrossRef Medline · DOI
  57. Nudmamud-Thanoi S, Thanoi S, Sobhon P (2006) Increase of glutamate/ N-methyl-D-aspartate receptor immunodensity in the dentate gyrus of rats following pseudoephedrine administration. Neurotoxicology 27: 623-627. CrossRef Medline · DOI
  58. Oberheim NA, Goldman SA, Nedergaard M (2012) Heterogeneity of astro- cytic form and function. Methods Mol Biol 814:23-45. CrossRef Medline · DOI · Paper page
  59. Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L (2007) Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 55:697-711. CrossRef Medline · DOI · Paper page
  60. Pekny M, Wilhelmsson U, Pekna M (2014) The dual role of astrocyte acti- vation and reactive gliosis. Neurosci Lett 565:30 -38. CrossRef Medline · DOI
  61. Pekny M, Pekna M, Messing A, Steinha ¨user C, Lee JM, Parpura V, Hol EM, Sofroniew MV, Verkhratsky A (2016) Astrocytes: a central element in neurological diseases. Acta Neuropathol 131:323-345. CrossRef Medline · DOI
  62. Peskind ER, Potkin SG, Pomara N, Ott BR, Graham SM, Olin JT, McDonald S (2006) Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial. Am J Geriatr Psychiatry 14:704 - 715. CrossRef Medline · DOI
  63. Pleiss MM, Sompol P, Kraner SD, Abdul HM, Furman JL, Guttmann RP, Wilcock DM, Nelson PT, Norris CM (2016) Calcineurin proteolysis in astrocytes: implications for impaired synaptic function. Biochim Biophys Acta 1862:1521-1532. CrossRef Medline · DOI
  64. Prokop S, Miller KR, Heppner FL (2013) Microglia actions in Alzheimer's disease. Acta Neuropathol 126:461-477. CrossRef Medline · DOI · Paper page
  65. Prow NA, Irani DN (2008) The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic mo- tor neuron injury in the spinal cord during acute viral encephalomyelitis. J Neurochem 105:1276 -1286. CrossRef Medline · DOI
  66. Putcha D, Brickhouse M, O'Keefe K, Sullivan C, Rentz D, Marshall G, Dick- erson B, Sperling R (2011) Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non- demented elderly adults. J Neurosci 31:17680 -17688. CrossRef Medline · DOI
  67. Rao VL, Dogan A, Bowen KK, Todd KG, Dempsey RJ (2001) Antisense knockdown of the glial glutamate transporter GLT-1 exacerbates hip- pocampal neuronal damage following traumatic injury to rat brain. Eur J Neurosci 13:119 -128. CrossRef Medline · DOI
  68. Reese LC, Zhang W, Dineley KT, Kayed R, Taglialatela G (2008) Selective induction of calcineurin activity and signaling by oligomeric amyloid beta. Aging Cell 7:824 -835. CrossRef Medline · DOI
  69. Reisberg B, Doody R, Sto ¨ffler A, Schmitt F, Ferris S, Mo ¨bius HJ (2003) Me- mantine in moderate-to-severe Alzheimer's disease. N Engl J Med 348: 1333-1341. CrossRef Medline · DOI · Paper page
  70. Rojanathammanee L, Floden AM, Manocha GD, Combs CK (2015) Atten- uation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibition. J Neuroinflammation 12:42. CrossRef Medline · DOI
  71. Rothstein JD, Dykes-Hoberg M, Pardo CA, Bristol LA, Jin L, Kuncl RW, Kanai Y, Hediger MA, Wang Y, Schielke JP, Welty DF (1996) Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16:675-686. CrossRef Medline · DOI · Paper page
  72. Sama MA, Mathis DM, Furman JL, Abdul HM, Artiushin IA, Kraner SD, Norris CM (2008) Interleukin-1beta-dependent signaling between as- trocytes and neurons depends critically on astrocytic calcineurin/NFAT activity. J Biol Chem 283:21953-21964. CrossRef Medline · DOI
  73. Sametsky EA, Disterhoft JF, Geinisman Y, Nicholson DA (2010) Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1 pyramidal neurons. Neurobiol Aging 31:813-825. CrossRef Medline · DOI
  74. Schallier A, Smolders I, Van Dam D, Loyens E, De Deyn PP, Michotte A, Michotte Y, Massie A (2011) Region-and age-specific changes in gluta- mate transport in the AbetaPP23 mouse model for Alzheimer's disease. J Alzheimers Dis 24:287-300. CrossRef Medline · DOI · Paper page
  75. Scho ¨ll M, Carter SF, Westman E, Rodriguez-Vieitez E, Almkvist O, Thordar- dottir S, Wall A, Graff C, Långstro ¨m B, Nordberg A (2015) Early astro- cytosis in autosomal dominant Alzheimer's disease measured in vivo by multi-tracer positron emission tomography. Sci Rep 5:16404. CrossRef Medline · DOI
  76. Schousboe A, Sarup A, Bak LK, Waagepetersen HS, Larsson OM (2004) Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission. Neurochem Int 45:521-527. CrossRef Medline · DOI
  77. Selkirk JV, Nottebaum LM, Vana AM, Verge GM, Mackay KB, Stiefel TH, Naeve GS, Pomeroy JE, Petroski RE, Moyer J, Dunlop J, Foster AC (2005) Role of the GLT-1 subtype of glutamate transporter in glutamate homeo- stasis: the GLT-1-preferring inhibitor WAY-855 produces marginal neu- rotoxicity in the rat hippocampus. Eur J Neurosci 21:3217-3228. CrossRef Medline · DOI
  78. Serrano-Pe ´rez MC, Martín ED, Vaquero CF, Azcoitia I, Calvo S, Cano E, Tranque P (2011) Response of transcription factor NFATc3 to excito- toxic and traumatic brain insults: identification of a subpopulation of reactive astrocytes. Glia 59:94 -107. CrossRef Medline · DOI
  79. Shioda N, Moriguchi S, Shirasaki Y, Fukunaga K (2006) Generation of consti- tutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia. J Neurochem 98:310 -320. CrossRef Medline · DOI
  80. Simpson JE, Ince PG, Lace G, Forster G, Shaw PJ, Matthews F, Savva G, Brayne C, Wharton SB (2010) Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain. Neurobiol Aging 31:578 - 590. CrossRef Medline · DOI · Paper page
  81. Spires TL, Hyman BT (2004) Neuronal structure is altered by amyloid plaques. Rev Neurosci 15:267-278. CrossRef Medline · DOI
  82. Su ZZ, Leszczyniecka M, Kang DC, Sarkar D, Chao W, Volsky DJ, Fisher PB (2003) Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2). Proc Natl Acad Sci U S A 100:1955-1960. CrossRef Medline · DOI
  83. Tackenberg C, Grinschgl S, Trutzel A, Santuccione AC, Frey MC, Konietzko U, Grimm J, Brandt R, Nitsch RM (2013) NMDA receptor subunit com- position determines beta-amyloid-induced neurodegeneration and syn- aptic loss. Cell Death Dis 4:e608. CrossRef Medline · DOI · Paper page
  84. Tariot PN, Farlow MR, Grossberg GT, Graham SM, McDonald S, Gergel I (2004) Memantine treatment in patients with moderate to severe Alzhei- mer disease already receiving donepezil: a randomized controlled trial. JAMA 291:317-324. CrossRef Medline · DOI · Paper page
  85. Tian R, Wu X, Hagemann TL, Sosunov AA, Messing A, McKhann GM, Gold- man JE (2010) Alexander disease mutant glial fibrillary acidic protein compromises glutamate transport in astrocytes. J Neuropathol Exp Neu- rol 69:335-345. CrossRef Medline · DOI
  86. Vossel KA, Ranasinghe KG, Beagle AJ, Mizuiri D, Honma SM, Dowling AF, Darwish SM, Van Berlo V, Barnes DE, Mantle M, Karydas AM, Coppola G, Roberson ED, Miller BL, Garcia PA, Kirsch HE, Mucke L, Nagarajan SS (2016) Incidence and impact of subclinical epileptiform activity in Alz- heimer's disease. Ann Neurol 80:858 -870. CrossRef Medline · DOI · Paper page
  87. Wu HY, Tomizawa K, Oda Y, Wei FY, Lu YF, Matsushita M, Li ST, Moriwaki A, Matsui H (2004) Critical role of calpain-mediated cleavage of cal- cineurin in excitotoxic neurodegeneration. J Biol Chem 279:4929 -4940. CrossRef Medline · DOI
  88. Wu HY, Hudry E, Hashimoto T, Kuchibhotla K, Rozkalne A, Fan Z, Spires- Jones T, Xie H, Arbel-Ornath M, Grosskreutz CL, Bacskai BJ, Hyman BT (2010) Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation. J Neurosci 30:2636 -2649. CrossRef Medline · DOI · Paper page
  89. Xu M, Dong Y, Wan S, Yan T, Cao J, Wu L, Bi K, Jia Y (2016) Schisantherin B ameliorates Abeta1-42-induced cognitive decline via restoration of GLT-1 in a mouse model of Alzheimer's disease. Physiol Behav 167:265- 273. CrossRef Medline · DOI
  90. R)PK11195. J Cereb Blood Flow Metab 37:877-889. CrossRef Medline · DOI
  91. Zumkehr J, Rodriguez-Ortiz CJ, Cheng D, Kieu Z, Wai T, Hawkins C, Kilian J, Lim SL, Medeiros R, Kitazawa M (2015) Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate trans- porter in a mouse model of Alzheimer's disease. Neurobiol Aging 36: 2260 -2271. CrossRef Medline · DOI

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Metadata

Authors
Sompol, P., Furman, J. L., Pleiss, M. M., Kraner, S. D., Artiushin, I. A., Batten, S. R., Quintero, J. E., Simmerman, L. A., Beckett, T. L., Lovell, M. A., Murphy, M. P., Gerhardt, G. A., & Norris, C. M.
Venue
The Journal of Neuroscience
Published
2017-05-30
Volume
37
Issue
25
Pages
6132-6148
ISSN
  • 0270-6474
  • 1529-2401
Cited by
123
References
16
Language
en

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