Parent, family, and neighborhood effects on the development of child substance use and other psychopathology from preschool to the start of adulthood
Open accessAbstract
OBJECTIVE: We examined the long-term effects of childhood familial and neighborhood risk on adolescent substance use and psychiatric symptomatology. METHOD: This study used data from an ongoing 2-decade long study that recruited alcoholic and neighborhood control families through fathers' drunk-driving records and door-to-door canvassing in a four county area. The sample included 220 male, initially 3- to 5-year-old children of the participant families, who received in-home assessments at baseline and thereafter at 3-year intervals. Parental lifetime psychopathology and offspring symptomatology at ages 18-20 were assessed by semistructured diagnostic interviews. Census tract variables were used to indicate neighborhood characteristics. RESULTS: The isomorphic parental symptomatology predicted offspring psychopathology. For marijuana-use disorder, major depressive disorder, and nicotine dependence, the other parental comorbidities were also significant predictors. Neighborhood residential instability in childhood contributed to the development of late adolescent alcohol-use disorder, marijuana-use disorder, major depressive disorder, antisocial personality disorder, and nicotine-dependence symptomatology. Although lower family socioeconomic status in childhood contributed to more adolescent marijuana-use disorder, major depressive disorder, and nicotine-dependence symptoms, neighborhood socioeconomic status did not predict adolescent psychopathology. Longitudinal changes in neighborhood environments from early childhood to adolescence had significant effects on alcohol-use disorder, marijuana-use disorder, and major depressive disorder symptoms in late adolescence. A higher frequency of family mobility from early childhood to adolescence predicted more nicotine-dependence symptoms in late adolescence. CONCLUSIONS: Findings indicate that parental psychopathology, family socioeconomic status, and neighborhood residential instability are all important risk factors for the development of substance-use disorder and other comorbid psychopathology. Intervention programming might effectively use these early parental psychopathology indicators to identify risk and might target community activity to stabilize the social environment and provide youth services to counteract the effects of family transience.
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Less deviant activity (including drug use) takes place in the neighborhoods of lower risk youth.
“This is also consistent with the findings that less deviant activity (including drug use) takes place in the neighborhoods of lower risk youth (Buu et al., 2009).”
From Assessment of culture and environment in the Adolescent Brain and Cognitive Development Study: Rationale, description of measures, and early data (2018) · cites this paper as Buu et al., 2009
The Poisson regression models section reports fewer alcohol-use disorder symptoms among youth whose neighborhoods became more stable and fewer marijuana-use disorder symptoms where neighborhoods became more affluent. That supports an association between neighborhood conditions and youths’ substance-use outcomes, but the paper does not establish that less deviant activity, including drug use, takes place across the neighborhoods of lower-risk youth. Page numbers were not available in our copy. (LLM, conf=0.83)
Experimental — accuracy not yet measuredNeighborhood social disorganizational characteristics, including crime, violence, and social instability, have problematic impact upon the children growing up in these contexts.
“Studies have shown that neighborhood social disorganizational characteristics, including crime, violence, and social instability—seemingly distal level characteristics—have problematic impact upon the children growing up in these contexts (Buu et al., 2009).”
From Assessment of culture and environment in the Adolescent Brain and Cognitive Development Study: Rationale, description of measures, and early data (2018) · cites this paper as Buu et al., 2009
The ‘Neighborhood residential instability’ section reports that frequent residential turnover during childhood contributed to all five adolescent psychopathology outcomes. The ‘Poisson regression models’ section likewise reports significant associations for residential instability. The paper does not establish the claimed impact of neighborhood crime or violence on the children studied, so the broader list of disorganizational characteristics is only partly supported. Page numbers were not available in our copy. (LLM, conf=0.88)
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- Authors
- Buu, A., DiPiazza, C., Wang, J., Puttler, L. I., Fitzgerald, H. E., & Zucker, R. A.
- Affiliations
- University of Michigan (US)
- Venue
- Journal of Studies on Alcohol and Drugs
- Publisher
- Alcohol Research Documentation, Inc.
- Published
- 2009-07
- Volume
- 70
- Issue
- 4
- Pages
- 489-498
- ISSN
- 1937-1888 (ISSN-L)
- 1938-4114
- PMC
- PMC2696289
- OpenAlex
- W2027094758
- Cited by
- 190
- References
- 39
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 11 · 2023: 4 · 2022: 10 · 2021: 7 · 2020: 15 · 2019: 10 · 2018: 13 · 2017: 16 · 2016: 13 · 2015: 14 · 2014: 16 · 2013: 12 · 2012: 17
- FWCI
- 8.73
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Studies on Alcohol and Drugs (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R37AA007065, R37 AA-07065)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Sociology and Political Science › Crime Patterns and Interventions
- Keywords
- adolescent psychopathology, parental psychopathology, neighborhood effects, residential instability, family socioeconomic status, family mobility, alcoholism, cannabis use disorder, nicotine dependence, major depressive disorder, antisocial personality disorder, comorbidities, risk factors, family history of alcoholism
- MeSH terms
- Adolescent, Alcoholism, Mental Disorders, Child, Child, Preschool, Family Health, Humans, Longitudinal Studies, Male, Models, Psychological, Parent-Child Relations, Residence Characteristics, Risk Factors, Social Class, Models, Statistical, Child of Impaired Parents, Substance-Related Disorders, Young Adult
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