Epigenetics of early-life lead exposure and effects on brain development

Epigenetic programming by maternal behavior

Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177 · see citing works

Regulation of chromatin by histone modifications

Bannister, A. J., & Kouzarides, T. (2011) · Cell Research · doi:10.1038/cr.2011.22 · Cited by 6,012 · see citing works

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L. M., Liu, D. R., Aravind, L., et al. (2009) · Science · doi:10.1126/science.1170116 · Cited by 5,836 · see citing works

DNA methylation and its basic function

Moore, L. D., Le, T., & Fan, G. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2012.112 · Cited by 4,906 · see citing works

Non-coding RNAs in human disease

Esteller, M. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3074 · Cited by 4,825 · see citing works

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

Li, E., Bestor, T. H., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90611-f · Cited by 3,984 · see citing works

The fetal and infant origins of adult disease.

Barker, D. J. (1990) · BMJ · doi:10.1136/bmj.301.6761.1111 · Cited by 2,768 · see citing works

Low-Level Environmental Lead Exposure and Children’s Intellectual Function: An International Pooled Analysis

Lanphear, B. P., Hornung, R., Khoury, J., Yolton, K., Baghurst, P., Bellinger, D. C., Canfield, R. L., Dietrich, K. N., Bornschein, R., Greene, T., et al. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7688 · Cited by 2,205 · see citing works

Intellectual Impairment in Children with Blood Lead Concentrations below 10 μg per Deciliter

Canfield, R. L., Henderson, C. R., Cory-Slechta, D. A., Cox, C., Jusko, T. A., & Lanphear, B. P. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022848 · Cited by 2,081 · see citing works

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

Zhang, S., Wernig, M., Duncan, I. D., Brüstle, O., & Thomson, J. A. (2001) · Nature Biotechnology · doi:10.1038/nbt1201-1129 · Cited by 1,916 · see citing works

Epigenetic regulation in psychiatric disorders

Tsankova, N., Renthal, W., Kumar, A., & Nestler, E. J. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2132 · Cited by 1,400 · see citing works

Induction of human neuronal cells by defined transcription factors

Pang, Z. P., Yang, N., Vierbuchen, T., Ostermeier, A., Fuentes, D., Yang, T. Q., Citri, A., Sebastiano, V., Marro, S. G., Südhof, T. C., et al. (2011) · Nature · doi:10.1038/nature10202 · Cited by 1,249 · see citing works

Neurotoxic Effects and Biomarkers of Lead Exposure: A Review

Sanders, T., Liu, Y., Buchner, V., & Tchounwou, P. B. (2009) · Reviews on Environmental Health · doi:10.1515/reveh.2009.24.1.15 · Cited by 1,084 · see citing works

Synergistic Signaling in Fetal Brain by STAT3-Smad1 Complex Bridged by p300

Nakashima, K., Yanagisawa, M., Arakawa, H., Kimura, N., Hisatsune, T., Kawabata, M., Miyazono, K., & Taga, T. (1999) · Science · doi:10.1126/science.284.5413.479 · Cited by 867 · see citing works

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

Szulwach, K. E., Li, X., Li, Y., Song, C., Wu, H., Dai, Q., Irier, H. A., Upadhyay, A. K., Gearing, M., Levey, A. I., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2959 · Cited by 818 · see citing works

Gender differences in the disposition and toxicity of metals

Vahter, M., Åkesson, A., Lidén, C., Ceccatelli, S., & Berglund, M. (2006) · Environmental Research · doi:10.1016/j.envres.2006.08.003 · Cited by 740 · see citing works

Reframing sexual differentiation of the brain

McCarthy, M. M., & Arnold, A. P. (2011) · Nature Neuroscience · doi:10.1038/nn.2834 · Cited by 728 · see citing works

Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells

Hsieh, J., Nakashima, K., Kuwabara, T., Mejia, E., & Gage, F. H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407643101 · Cited by 724 · see citing works

Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children

Braun, J. M., Kahn, R. S., Froehlich, T., Auinger, P., & Lanphear, B. P. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.9478 · Cited by 573 · see citing works

Histone Methylation Regulates Memory Formation

Gupta, S., Kim, S. Y., Artis, S., Molfese, D. L., Schumacher, A., Sweatt, J. D., Paylor, R. E., & Lubin, F. D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3732-09.2010 · Cited by 562 · see citing works

Environmental chemical exposures and human epigenetics

Hou, L., Zhang, X., Wang, D., & Baccarelli, A. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr154 · Cited by 489 · see citing works

Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

Wu, J., Basha, R. M., Brock, B., Cox, D. P., Cardozo‐Pelaez, F., McPherson, C. A., Harry, J., Rice, D. C., Maloney, B., Chen, D., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4405-07.2008 · Cited by 473 · see citing works

Association of Prenatal and Childhood Blood Lead Concentrations with Criminal Arrests in Early Adulthood

Wright, J. P., Dietrich, K. N., Ris, M. D., Hornung, R. W., Wessel, S. D., Lanphear, B. P., Ho, M., & Rae, M. N. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050101 · Cited by 467 · see citing works

Decreased Brain Volume in Adults with Childhood Lead Exposure

Cecil, K. M., Brubaker, C. J., Adler, C. M., Dietrich, K. N., Altaye, M., Egelhoff, J. C., Wessel, S., Elangovan, I., Hornung, R., Jarvis, K., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050112 · Cited by 458 · see citing works

Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

Lujan, E., Chanda, S., Ahlenius, H., Südhof, T. C., & Wernig, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121003109 · Cited by 421 · see citing works

New and evolving concepts in the neurotoxicology of lead☆

White, L. D., Cory‐Slechta, D. A., Gilbert, M. E., Tiffany‐Castiglioni, E., Zawia, N. H., Virgolini, M. B., Rossi‐George, A., Lasley, S. M., Qian, Y., & Basha, R. M. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.08.001 · Cited by 404 · see citing works

MicroRNAs in neuronal function and dysfunction

Im, H.-I., & Kenny, P. J. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.01.004 · Cited by 399 · see citing works

Epigenetic control of neural precursor cell fate during development

Hirabayashi, Y., & Gotoh, Y. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2810 · Cited by 376 · see citing works

The Fetal Basis of Amyloidogenesis: Exposure to Lead and Latent Overexpression of Amyloid Precursor Protein and β-Amyloid in the Aging Brain

Basha, R. M., Wei, W., Bakheet, S. A., Benitez, N. B., Siddiqi, H. K., Ge, Y., Lahiri, D. K., & Zawia, N. H. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4335-04.2005 · Cited by 353 · see citing works

Environmental epigenetics in metal exposure

Martínez‐Zamudio, R. I., & Ha, H. C. (2011) · Epigenetics · doi:10.4161/epi.6.7.16250 · Cited by 324 · see citing works

Neuropsychological function in children with blood lead levels <10μg/dL

Surkan, P. J., Zhang, A., Trachtenberg, F. L., DANIEL, D., McKinlay, S. M., & Bellinger, D. C. (2007) · NeuroToxicology · doi:10.1016/j.neuro.2007.07.007 · Cited by 318 · see citing works

Teratogen update: Lead and pregnancy

Bellinger, D. C. (2005) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20127 · Cited by 317 · see citing works

Transplacental transport of lead.

Goyer, R. A. (1990) · Environmental Health Perspectives · doi:10.1289/ehp.9089101 · Cited by 305 · see citing works

Transgenerational epigenetic inheritance: More questions than answersPreprint

Daxinger, L., & Whitelaw, E. (2010) · Genome Research · doi:10.1101/gr.106138.110 · Cited by 305 · see citing works

Histone Deacetylase Activity Is Necessary for Oligodendrocyte Lineage Progression

Marin‐Husstege, M., Muggironi, M., Liu, A., & Casaccia-Bonnefil, P. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-23-10333.2002 · Cited by 293 · see citing works

Lead

Bellinger, D. C. (2004) · PEDIATRICS · doi:10.1542/peds.113.s3.1016 · Cited by 287 · see citing works

Influence of Prenatal Lead Exposure on Genomic Methylation of Cord Blood DNA

Pilsner, J. R., Hu, H., Ettinger, A., Sánchez, B. N., Wright, R. O., Cantonwine, D., Lazarus, A., Lamadrid-Figueroa, H., Mercado-García, A., Téllez-Rojo, M. M., et al. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800497 · Cited by 275 · see citing works

Epigenetic Regulation of Neural Gene Expression and Neuronal Function

Feng, J., Fouse, S. D., & Fan, G. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e3180457635 · Cited by 263 · see citing works

Genomic Imprinting: A Mammalian Epigenetic Discovery Model

Barlow, D. P. (2011) · Annual Review of Genetics · doi:10.1146/annurev-genet-110410-132459 · Cited by 256 · see citing works

Biomarkers of Lead Exposure and DNA Methylation within Retrotransposons

Wright, R. O., Schwartz, J., Wright, R. J., Bollati, V., Tarantini, L., Park, S. K., Hu, H., Sparrow, D., Vokonas, P., & Baccarelli, A. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901429 · Cited by 235 · see citing works

Molecular Neurobiology of Lead (Pb2+): Effects on Synaptic Function

Neal, A. P., & Guilarte, T. R. (2010) · Molecular Neurobiology · doi:10.1007/s12035-010-8146-0 · Cited by 203 · see citing works

Confirmation and extension of association of blood lead with attention‐deficit/hyperactivity disorder (ADHD) and ADHD symptom domains at population‐typical exposure levels

Nigg, J. T., Nikolas, M. A., Knottnerus, G. M., CAVANAGH, K. T., & Friderici, K. H. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2009.02135.x · Cited by 202 · see citing works

Epigenetic targets of some toxicologically relevant metals: a review of the literature

Cheng, T., Choudhuri, S., & Muldoon‐Jacobs, K. (2012) · Journal of Applied Toxicology · doi:10.1002/jat.2717 · Cited by 189 · see citing works

Co-exposure to environmental lead and manganese affects the intelligence of school-aged children

Kim, Y., Kim, B.-N., Hong, Y., Shin, M., Yoo, H., Kim, J.-W., Bhang, S., & Cho, S.-C. (2009) · NeuroToxicology · doi:10.1016/j.neuro.2009.03.012 · Cited by 187 · see citing works

Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal

Waly, M. I., Olteanu, H., Banerjee, R. V., Choi, S.-W., Mason, J. B., Parker, B. S., Sukumar, S. V., Shim, S., Sharma, A. K., Benzecry, J., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001476 · Cited by 164 · see citing works

DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF

Hanna, C. W., Bloom, M. S., Robinson, W. P., Kim, D., Parsons, P. J., vom Saal, F. S., Taylor, J. A., Steuerwald, A. J., & Fujimoto, V. Y. (2012) · Human Reproduction · doi:10.1093/humrep/des038 · Cited by 163 · see citing works

Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain: implications for Alzheimer’s disease

Bihaqi, S. W., Huang, H., Wu, J., & Zawia, N. H. (2011) · Journal of Alzheimer’s Disease · doi:10.3233/jad-2011-111013 · Cited by 162 · see citing works

Hypothesis: Environmental regulation of 5-hydroxymethylcytosine by oxidative stress

Chia, N., Wang, L., Lu, X., Senut, M., Brenner, C. A., & Ruden, D. M. (2011) · Epigenetics · doi:10.4161/epi.6.7.16461 · Cited by 157 · see citing works

Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory

Li, H., Zhong, X., Chau, K. F., Williams, E. C., & Chang, Q. (2011) · Nature Neuroscience · doi:10.1038/nn.2866 · Cited by 153 · see citing works

Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases

Marchetto, M. C. N., Winner, B., & Gage, F. H. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq159 · Cited by 152 · see citing works

Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats

Verina, T., Rohde, C. A., & Guilarte, T. R. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.12.040 · Cited by 150 · see citing works

Gender specific differences in neurodevelopmental effects of prenatal exposure to very low-lead levels: The prospective cohort study in three-year olds

Jedrychowski, W. A., Perera, F. P., Jankowski, J. J., Mrozek‐Budzyn, D., Mróz, E., Flak, E., Edwards, S., Skarupa, A., & Lisowska‐Miszczyk, I. (2009) · Early Human Development · doi:10.1016/j.earlhumdev.2009.04.006 · Cited by 133 · see citing works

Altered myelination and axonal integrity in adults with childhood lead exposure: A diffusion tensor imaging study

Brubaker, C. J., Schmithorst, V. J., Haynes, E. N., Dietrich, K. N., Egelhoff, J. C., Lindquist, D. M., Lanphear, B. P., & Cecil, K. M. (2009) · NeuroToxicology · doi:10.1016/j.neuro.2009.07.007 · Cited by 132 · see citing works

The Protean Toxicities of Lead: New Chapters in a Familiar Story

Bellinger, D. C. (2011) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph8072593 · Cited by 132 · see citing works

Low-Level Human Equivalent Gestational Lead Exposure Produces Sex-Specific Motor and Coordination Abnormalities and Late-Onset Obesity in Year-Old Mice

Leasure, J. L., Giddabasappa, A., Chaney, S., Johnson, J. E., Pothakos, K., Lau, Y., & Fox, D. A. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10862 · Cited by 128 · see citing works

Crosstalk among Epigenetic Pathways Regulates Neurogenesis

Jobe, E. M., McQuate, A. L., & Zhao, X. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00059 · Cited by 124 · see citing works

The Impact of Early Childhood Lead Exposure on Brain Organization: A Functional Magnetic Resonance Imaging Study of Language Function

Yuan, W., Holland, S. K., Cecil, K. M., Dietrich, K. N., Wessel, S. D., Altaye, M., Hornung, R., Ris, M. D., Egelhoff, J. C., & Lanphear, B. P. (2006) · PEDIATRICS · doi:10.1542/peds.2006-0467 · Cited by 116 · see citing works

Dysregulation of BDNF-TrkB Signaling in Developing Hippocampal Neurons by Pb2+: Implications for an Environmental Basis of Neurodevelopmental Disorders

Stansfield, K. H., Pilsner, J. R., Lu, Q., Wright, R. O., & Guilarte, T. R. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs090 · Cited by 105 · see citing works

Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing

Zimmer, B., Kuegler, P. B., Baudis, B., Genewsky, A. J., Tanavde, V., Koh, W. L. C., Tan, B., Waldmann, T., Kadereit, S., & Leist, M. (2010) · Cell Death and Differentiation · doi:10.1038/cdd.2010.109 · Cited by 101 · see citing works

Neurotoxicity in young adults 20 years after childhood exposure to lead: the Bunker Hill experience.

Stokes, L., Letz, R., Gerr, F. E., et al. (1998) · Occupational and Environmental Medicine · doi:10.1136/oem.55.8.507 · Cited by 99 · see citing works

Epigenetic mechanisms in metal toxicity

Fragou, D., Fragou, A., Kouidou, S., Njau, S. N., & Kovatsi, L. (2011) · Toxicology Mechanisms and Methods · doi:10.3109/15376516.2011.557878 · Cited by 97 · see citing works

Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses

Guilarte, T. R., Opler, M. G., & Pletnikov, M. V. (2011) · NeuroToxicology · doi:10.1016/j.neuro.2011.11.008 · Cited by 95 · see citing works

Genome-wide expression and methylation profiling in the aged rodent brain due to early-life Pb exposure and its relevance to aging

Dosunmu, R., Alashwal, H., & Zawia, N. H. (2012) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2012.05.003 · Cited by 91 · see citing works

Lead.

Bellinger, D. C. (2004) · PubMed · Cited by 81 · see citing works

Epigenetic Assessment of Environmental Chemicals Detected in Maternal Peripheral and Cord Blood Samples

Yoshikazu, A. R. A. I., Ohgane, J., Yagi, S., Ito, R., Iwasaki, Y., Saito, K., Akutsu, K., Takatori, S., Ishii, R., Hayashi, R., et al. (2011) · Journal of Reproduction and Development · doi:10.1262/jrd.11-034a · Cited by 74 · see citing works

Chromosome silencing mechanisms in X-chromosome inactivation: unknown unknowns

Brockdorff, N. (2011) · Development · doi:10.1242/dev.065276 · Cited by 70 · see citing works

Prenatal Lead Levels, Plasma Amyloid β Levels, and Gene Expression in Young Adulthood

Mazumdar, M., Xia, W., Hofmann, O., Gregas, M. C., Sui, S. H., Hide, W., Yang, T., Needleman, H. L., & Bellinger, D. C. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104474 · Cited by 65 · see citing works

<i>p16</i>promoter methylation in Pb²⁺-exposed individuals

Kovatsi, L., Georgiou, E., Ioannou, A., Haitoglou, C., Tzimagiorgis, G., Tsoukali, H., & Kouidou, S. (2010) · Clinical Toxicology · doi:10.3109/15563650903567091 · Cited by 58 · see citing works

Enhanced Learning Deficits in Female Rats Following Lifetime Pb Exposure Combined with Prenatal Stress

Cory‐Slechta, D. A., Stern, S., Weston, D., Allen, J. L., & Liu, S. M. (2010) · Toxicological Sciences · doi:10.1093/toxsci/kfq221 · Cited by 55 · see citing works

Effects of Developmental Lead Exposure on the Hippocampal Transcriptome: Influences of Sex, Developmental Period, and Lead Exposure Level

Schneider, J. S., Anderson, D. W., Talsania, K., Mettil, W., & Vadigepalli, R. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs189 · Cited by 53 · see citing works

Lead Dysregulates Serine/Threonine Protein Phosphatases in Human Neurons

Rahman, A., Brew, B. J., & Guillemin, G. J. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0300-6 · Cited by 48 · see citing works

Genetic Variation in the Epigenetic Machinery and Mental Health

Murgatroyd, C., & Spengler, D. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-012-0255-1 · Cited by 41 · see citing works

Effects of maternal lead exposure on functional plasticity in the visual cortex and hippocampus of immature rats

Altmann, L., Gutowski, M., & Wiegand, H. (1994) · Developmental Brain Research · doi:10.1016/0165-3806(94)90067-1 · Cited by 38 · see citing works

Sex-based differences in gene expression in hippocampus following postnatal lead exposure

Schneider, J. S., Anderson, D. W., Sonnenahalli, H., & Vadigepalli, R. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.08.008 · Cited by 38 · see citing works

Exposure of women in general populations to lead via food and air in East and Southeast Asia

Ikeda, M., Zhang, Z.-W., Shimbo, S., Watanabe, T., Nakatsuka, H., Moon, C., Matsuda‐Inoguchi, N., & Higashikawa, K. (2000) · American Journal of Industrial Medicine · doi:10.1002/1097-0274(200009)38:3 · Cited by 36 · see citing works

Chronic lead exposure alters presynaptic calcium regulation and synaptic facilitation in Drosophila larvae

He, T., Hirsch, H. V. B., Ruden, D. M., et al. (2009) · NeuroToxicology · doi:10.1016/j.neuro.2009.08.007 · Cited by 32 · see citing works

Protective effect of 17-β-estradiol in human neurocellular models of lead exposure

Chetty, C. S., Vemuri, M. C., Reddy, G. R., & Challa, S. (2006) · NeuroToxicology · doi:10.1016/j.neuro.2006.03.012 · Cited by 23 · see citing works

Panel Advises Tougher Limits on Lead Exposure

Kuehn, B. M. (2012) · JAMA · doi:10.1001/jama.2012.50 · Cited by 10 · see citing works

Lead Exposure Disrupts Global DNA Methylation in Human Embryonic Stem Cells and Alters Their Neuronal Differentiation

Senut, M.-C., Sen, A., Cingolani, P., Shaik, A., Land, S. J., & Ruden, D. M. (2014) · Toxicological Sciences · doi:10.1093/toxsci/kfu028 · Cited by 135 · see citing works

Prenatal ambient air pollution exposure and SOD2 promoter methylation in maternal and cord blood

Zhou, G., He, T., Huang, H., Feng, F., Liu, X., Li, Z., Zhang, Y., & Ba, Y. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.06.039 · Cited by 35 · see citing works

The clinical use of epigenetics in psychiatry: a narrative review of epigenetic mechanisms, key candidate genes, and precision psychiatry

Montel Hayes, R., Mason, C. E., & Miller, J. J. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1671122 · Cited by 5 · see citing works

Genetic and Environmental Impacts on DNA Methylation Levels in Twins

Yet, I., Tsai, P.-C., Castillo-Fernandez, J. E., Carnero-Montoro, E., & Bell, J. T. (2016) · Epigenomics · doi:10.2217/epi.15.90 · Cited by 36 · see citing works

[Tobacco and DNA methylation: the case for epigenetic alterations].

Bouzigon, E., & Barouki, R. (2021) · PubMed

DNA methylation in osteoarthritic chondrocytes: a new molecular target.

Roach, H., & Aigner, T. (2007) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2006.07.002 · Cited by 92 · see citing works

Early Nutritional Influences on Human Developmental Epigenetics

Waterland, R. A. (2015) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.61.s82

The Interplay between Dysregulated Metabolism and Epigenetics in Cancer

Bassal, M. A. (2023) · Biomolecules · doi:10.3390/biom13060944 · Cited by 19 · see citing works