Methyl-CpG-Binding Domain Proteins: Readers of the Epigenome

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins

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SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

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Heterochromatin revisited

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Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

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The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation

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Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

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MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

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REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis

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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system

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Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

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TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

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5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

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Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

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Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

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Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor

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Mice with Truncated MeCP2 Recapitulate Many Rett Syndrome Features and Display Hyperacetylation of Histone H3

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Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)

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Replication-Dependent Marking of DNA by PCNA Facilitates CAF-1-Coupled Inheritance of Chromatin

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LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer

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Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

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Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

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The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

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DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45

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Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

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Three-dimensional genome architecture: players and mechanisms

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Enhancer decommissioning by LSD1 during embryonic stem cell differentiation

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Human SWI/SNF-Associated PRMT5 Methylates Histone H3 Arginine 8 and Negatively Regulates Expression of ST7 and NM23 Tumor Suppressor Genes

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Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

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Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

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Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation

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Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

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Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse developmentPreprint

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PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing

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The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

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Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

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Deterministic direct reprogramming of somatic cells to pluripotency

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Histone arginine methylation

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DNA methylation and methyl-CpG binding proteins: developmental requirements and function

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Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

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Corepressor-Dependent Silencing of Chromosomal Regions Encoding Neuronal Genes

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Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells

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De Novo Mutations in Moderate or Severe Intellectual Disability

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Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genesPreprint

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Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

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Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia

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Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function

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A Family of Human Zinc Finger Proteins That Bind Methylated DNA and Repress Transcription

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The NuRD component Mbd3 is required for pluripotency of embryonic stem cells

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Methylation-Dependent and -Independent Genomic Targeting Principles of the MBD Protein Family

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Nucleosome Remodeling and Epigenetics

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Reduced meCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation

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MBD2/NuRD and MBD3/NuRD, Two Distinct Complexes with Different Biochemical and Functional Properties

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Intergenic Transcripts Regulate the Epigenetic State of rRNA Genes

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Methyl-CpG-binding Protein, MeCP2, Is a Target Molecule for Maintenance DNA Methyltransferase, Dnmt1

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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain

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Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

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NoRC—a novel member of mammalian ISWI‐containing chromatin remodeling machines

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Solution Structure of the Methyl-CpG Binding Domain of Human MBD1 in Complex with Methylated DNA

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Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing

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Methyl-CpG Binding Domain 1 (MBD1) Interacts with the Suv39h1-HP1 Heterochromatic Complex for DNA Methylation-based Transcriptional Repression

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Chromatin Compaction by Human MeCP2

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Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome

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Molecular Coupling of DNA Methylation and Histone Methylation

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Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized

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MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

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Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation

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NuRD‐mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

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Expression of mRNA for DNA methyltransferases and methyl-CpG–binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis

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Active Repression of Methylated Genes by the Chromosomal Protein MBD1

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Assessment of 2q23.1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder

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The HP1α–CAF1–SetDB1‐containing complex provides H3K9me1 for Suv39‐mediated K9me3 in pericentric heterochromatin

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The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

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Transcriptional Gene Silencing Promotes DNA Hypermethylation through a Sequential Change in Chromatin Modifications in Cancer Cells

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Identification of MeCP2 mutations in a series of females with autistic disorder

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NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment

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Methyl CpG–binding proteins induce large-scale chromatin reorganization during terminal differentiation

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The Ski protein family is required for MeCP2-mediated transcriptional repression.

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The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

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Mining cancer methylomes: prospects and challenges

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Structure and function of the nucleosome-binding PWWP domain

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Mbd1 Is Recruited to both Methylated and Nonmethylated CpGs via Distinct DNA Binding Domains

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ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain

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Mbd4 inactivation increases C→T transition mutations and promotes gastrointestinal tumor formation

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Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells

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Deficiency of Mbd2 suppresses intestinal tumorigenesis

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Epigenetic Mechanism of rRNA Gene Silencing: Temporal Order of NoRC-Mediated Histone Modification, Chromatin Remodeling, and DNA Methylation

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Components of the DNA Methylation System of Chromatin Control Are RNA-binding Proteins

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Comparative study of methyl-CpG-binding domain proteins

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Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases

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MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation

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MBD2‐MBD3 complex binds to hemi‐methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase

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The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes

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p66α–MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2–NuRD complex

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A Novel Family of Bromodomain Genes

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Isolation, physical mapping, and Northern analysis of the X-linked human gene encoding methyl CpG-binding protein, MECP2

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Transcriptional Repression and Heterochromatin Formation by MBD1 and MCAF/AM Family Proteins

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A Profile of Methyl-CpG Binding Domain Protein Occupancy of Hypermethylated Promoter CpG Islands of Tumor Suppressor Genes in Human Cancer

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MECP2 structural and 3′‐UTR variants in schizophrenia, autism and other psychiatric diseases: A possible association with autism

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c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex

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Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency

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Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences

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The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes

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MBD3, a Component of the NuRD Complex, Facilitates Chromatin Alteration and Deposition of Epigenetic Marks

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Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability

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The MBD protein family—Reading an epigenetic mark?

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MBD3 Localizes at Promoters, Gene Bodies and Enhancers of Active Genes

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The Minimal Repression Domain of MBD2b Overlaps with the Methyl-CpG-binding Domain and Binds Directly to Sin3A

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Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells

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The Human Proteins MBD5 and MBD6 Associate with Heterochromatin but They Do Not Bind Methylated DNA

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The Thymine DNA Glycosylase MBD4 Represses Transcription and Is Associated with Methylated p16 INK4a and hMLH1 Genes

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MBD5 and MBD6 interact with the human PR‐DUB complex through their methyl‐CpG‐binding domain

Baymaz, H. I., Fournier, A., Laget, S., Ji, Z., Jansen, P. W. T. C., Smits, A. H., Ferry, L., Mensinga, A., Poser, I., Sharrocks, A. D., et al. (2014) · PROTEOMICS · doi:10.1002/pmic.201400013 · Cited by 110

MCAF Mediates MBD1-Dependent Transcriptional Repression

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Two Highly Related p66 Proteins Comprise a New Family of Potent Transcriptional Repressors Interacting with MBD2 and MBD3

Marc, B., Boeke, J., Zhang, R., & Renkawitz, R. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207467200 · Cited by 105

Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation

Hashimoto, H., Zhang, X., & Cheng, X. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks628 · Cited by 105

Involvement of SUMO Modification in MBD1- and MCAF1-mediated Heterochromatin Formation

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The methyl-CpG binding protein MBD1 is required for PML-RARα function

Villa, R., Morey, L., Raker, V. A., Buschbeck, M., Gutiérrez, A., Santis, F. D., Corsaro, M., Varas, F., Bossi, D., Minucci, S., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509343103 · Cited by 100

An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex

Desai, M., Webb, H., Sinanan, L. M., Scarsdale, J. N., Walavalkar, N. M., Ginder, G. D., & Williams, D. C. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv168 · Cited by 97

Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells.

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The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation

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The Expanding Role of MBD Genes in Autism: Identification of a MECP2 Duplication and Novel Alterations in MBD5, MBD6, and SETDB1

Cukier, H. N., Lee, J. M., Ma, D., Young, J. I., Mayo, V., Butler, B. L., Ramsook, S. S., Rantus, J. A., Abrams, A. J., Whitehead, P. L., et al. (2012) · Autism Research · doi:10.1002/aur.1251 · Cited by 89

Reciprocal deletion and duplication at 2q23.1 indicates a role for MBD5 in autism spectrum disorder

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Overexpression of MBD2 in Glioblastoma Maintains Epigenetic Silencing and Inhibits the Antiangiogenic Function of the Tumor Suppressor Gene BAI1

Zhu, D., HUNTER, S. B., Vertino, P. M., & Meir, E. G. V. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-1157 · Cited by 84

Haploinsufficiency of MBD5 associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures

Williams, S. R., Mullegama, S. V., Rosenfeld, J. A., Dagli, A. I., Hatchwell, E., Allen, W., Williams, C. A., & Elsea, S. H. (2009) · European Journal of Human Genetics · doi:10.1038/ejhg.2009.199 · Cited by 84

Control of the DNA Methylation System Component MBD2 by Protein Arginine Methylation

Tan, C. P., & Nakielny, S. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00473-06 · Cited by 82

Transcript overexpression of theMBD2andMBD4genes in CD4+ T cells from systemic lupus erythematosus patients

Balada, E., Ordi‐Ros, J., Serrano‐Acedo, S., Martínez‐Lostao, L., & Vilardell, M. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0107064 · Cited by 82

CLLD8/KMT1F Is a Lysine Methyltransferase That Is Important for Chromosome Segregation

Falandry, C., Fourel, G., Galy, V., Ristriani, T., Horard, B., Simon, E. B., Salles, G., Gilson, É., & Magdinier, F. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.052399 · Cited by 81

TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters

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Novel variants identified in methyl-CpG-binding domain genes in autistic individuals

Cukier, H. N., Rabionet, R., Konidari, I., Rayner‐Evans, M. Y., Baltos, M. L., Wright, H. H., Abramson, R. K., Martin, E. R., Cuccaro, M. L., Pericak‐Vance, M. A., et al. (2009) · Neurogenetics · doi:10.1007/s10048-009-0228-7 · Cited by 79

Characterization of Dnmt3b:Thymine-DNA Glycosylase Interaction and Stimulation of Thymine Glycosylase-Mediated Repair by DNA Methyltransferase(s) and RNA

Boland, M. J., & Christman, J. K. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.02.049 · Cited by 77

p66 and p66 of the Mi-2/NuRD complex mediate MBD2 and histone interaction

Brackertz, M. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkj437 · Cited by 75

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation

Singleton, M. K., Gonzales, M. L., Leung, K., Yasui, D. H., Schroeder, D. I., Dunaway, K. W., & LaSalle, J. M. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.03.011 · Cited by 74

MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status

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Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping

Kernohan, K. D., Vernimmen, D., Gloor, G. B., & Bérubé, N. G. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku564 · Cited by 72

Disruption of MBD5 contributes to a spectrum of psychopathology and neurodevelopmental abnormalities

Hodge, J. C., Mitchell, E. L. D., Pillalamarri, V., Toler, T. L., Bartel, F., Kearney, H. M., Zou, Y. S., Tan, W., Hanscom, C., Kirmani, S., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.42 · Cited by 67

Antithetic Effects of MBD2a on Gene Regulation

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Methyl‐CpG‐binding protein 2 polymorphisms and vulnerability to autism

Loat, C. S., Curran, S. R., Lewis, C. M., Duvall, J. A., Geschwind, D. H., Bolton, P., & Craig, I. (2008) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2008.00414.x · Cited by 66

Probing the Dynamic Distribution of Bound States for Methylcytosine-binding Domains on DNA

Cramer, J. M., Scarsdale, J. N., Walavalkar, N. M., Buchwald, W. A., Ginder, G. D., & Williams, D. C. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.512236 · Cited by 66

MBD2 and Multiple Domains of CHD4 Are Required for Transcriptional Repression by Mi-2/NuRD Complexes

Ramírez, J. A., Dege, C., Kutateladze, T. G., & Hagman, J. R. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00819-12 · Cited by 60

MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress

Laget, S., Miotto, B., Chin, H. G., Estève, P., Roberts, R. J., Pradhan, S., & Defossez, P. (2014) · Epigenetics · doi:10.4161/epi.27695 · Cited by 58

Involvement of a Novel Zinc Finger Protein, MIZF, in Transcriptional Repression by Interacting with a Methyl-CpG-binding Protein, MBD2

Sekimata, M., Takahashi, A., Murakami, A., & Homma, Y. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107048200 · Cited by 57

Genome-wide profiling of DNA methylation in human cancer cells

Ogoshi, K., Hashimoto, S.-I., Nakatani, Y., Qü, W., Oshima, K., Tokunaga, K., Sugano, S., Hattori, M., Morishita, S., & Matsushima, K. (2011) · Genomics · doi:10.1016/j.ygeno.2011.07.003 · Cited by 54

Up-Regulation of MBD1 Promotes Pancreatic Cancer Cell Epithelial-Mesenchymal Transition and Invasion by Epigenetic Down-Regulation of E-Cadherin

Xu, J., Zhu, W., Xu, W., Yao, W., Zhang, B., Xu, Y., Ji, S., Liu, C., Long, J., Ni, Q., et al. (2013) · Current Molecular Medicine · doi:10.2174/1566524011313030008 · Cited by 54

Methyl-CpG–DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2

Patra, S. K., Patra, A., Zhao, H. L., Carroll, P. R., & Dahiya, R. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00253-5 · Cited by 52

Frameshift mutations in the MBD4/MED1 gene in primary gastric cancer with high-frequency microsatellite instability

Yamada, T., Koyama, T., Ohwada, S., Tago, K.-I., Sakamoto, I., Yoshimura, S., 浜田, 邦., Takeyoshi, I., & Morishita, Y. (2002) · Cancer Letters · doi:10.1016/s0304-3835(02)00043-5 · Cited by 51

Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization

Casas-Delucchi, C. S., Becker, A., Bolius, J. J., & Cardoso, M. C. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks784 · Cited by 51

The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation

Choi, W., Jeon, B.-N., Yoon, J.-H., Koh, D.-I., Kim, M.-H., Yu, M.-Y., Lee, K., Kim, Y., Kim, K., Hur, S. S., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt359 · Cited by 51

Unusual Characteristics of the DNA Binding Domain of Epigenetic Regulatory Protein MeCP2 Determine Its Binding Specificity

Khrapunov, S. N., Warren, C. L., Cheng, H., Berko, E. R., Greally, J. M., & Brenowitz, M. D. (2014) · Biochemistry · doi:10.1021/bi500424z · Cited by 51

Genome-Wide Binding of MBD2 Reveals Strong Preference for Highly Methylated Loci

Menafra, R., Brinkman, A. B., Matarese, F., Franci, G., Bartels, S. J. J., Nguyen, L. N. M., Shimbo, T., Wade, P. A., Hubner, N. C., & Stunnenberg, H. G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0099603 · Cited by 50

The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming

Cunha, S., Lin, Y., Goossen, E. A., DeVette, C. I., Albertella, M. R., Thomson, S., Mulvihill, M. J., & Welm, A. L. (2014) · Cell Reports · doi:10.1016/j.celrep.2013.12.010 · Cited by 48

MeCP2 and MBD2 expression during normal and pathological growth of the human mammary gland

Billard, L.-M., Magdinier, F., Lenoir, G., Frappart, L., & Dante, R. (2002) · Oncogene · doi:10.1038/sj.onc.1205357 · Cited by 47

CpG island promoter methylation and silencing of 14-3-3σ gene expression in LNCaP and Tramp-C1 prostate cancer cell lines is associated with methyl-CpG-binding protein MBD2

Pulukuri, S., & Rao, J. (2006) · Oncogene · doi:10.1038/sj.onc.1209462 · Cited by 46

Differential Recruitment of Methyl CpG‐Binding Domain Factors and DNA Methyltransferases by the Orphan Receptor Germ Cell Nuclear Factor Initiates the Repression and Silencing of Oct4

Gu, P., Xu, X., Menuet, D. L., Chung, A. C.-K., & Cooney, A. J. (2011) · Stem Cells · doi:10.1002/stem.652 · Cited by 46

Overlapping Roles of the Methylated DNA-binding Protein MBD1 and Polycomb Group Proteins in Transcriptional Repression of HOXA Genes and Heterochromatin Foci Formation

Sakamoto, Y., Watanabe, S., Ichimura, T., Kawasuji, M., Koseki, H., Baba, H., & Nakao, M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700011200 · Cited by 45

Direct Homo- and Hetero-Interactions of MeCP2 and MBD2

Becker, A., Allmann, L., Hofstätter, M., Casà, V., Weber, P., Lehmkuhl, A., Herce, H. D., & Cardoso, M. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053730 · Cited by 42

The Drosophila methyl-DNA binding protein MBD2/3 interacts with the NuRD complex via p55 and MI-2

Marhold, J., Brehm, A., & Kramer, K. (2004) · BMC Molecular Biology · doi:10.1186/1471-2199-5-20 · Cited by 40

Transcription onset of genes critical in liver carcinogenesis is epigenetically regulated by methylated DNA-binding protein MBD2

Stefañska, B., Suderman, M. J., Machnes, Z. M., Bhattacharyya, B., Hallett, M. T., & Moshe Szyf, A. (2013) · Carcinogenesis · doi:10.1093/carcin/bgt273 · Cited by 35

MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers

Bader, S. A., Walker, M., McQueen, H. A., Sellar, R., Oei, E., Wopereis, S., Zhu, Y., Peter, A., Bird, A. P., & Harrison, D. J. (2003) · Oncogene · doi:10.1038/sj.onc.1206574 · Cited by 34

Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells

Chatagnon, A., Bougel, S., Perriaud, L., Lachuer, J., Benhattar, J., & Dante, R. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn240 · Cited by 33

Associations between aberrant DNA methylation and transcript levels of DNMT1 and MBD2 in CD4+T cells from patients with systemic lupus erythematosus

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