Instrumental Variables Regression with Weak Instruments
Abstract
This paper develops asymptotic distribution theory for instrumental variable regression when the partial correlation between the instruments and a single included endogenous variable is weak, here modeled as local to zero. Asymptotic representations are provided for various instrumental variable statistics, including the two-stage least squares (TSLS) and limited information maximum- likelihood (LIML) estimators and their t-statistics. The asymptotic distributions are found to provide good approximations to sampling distributions with just 20 observations per instrument. Even in large samples, TSLS can be badly biased, but LIML is, in many cases, approximately median unbiased. The theory suggests concrete quantitative guidelines for applied work. These guidelines help to interpret Angrist and Krueger's (1991) estimates of the returns to education: whereas TSLS estimates with many instruments approach the OLS estimate of 6%, the more reliable LIML and TSLS estimates with fewer instruments fall between 8% and 10%, with a typical confidence interval of (6%, 14%).
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Following the rule of thumb suggested by Staiger and Stock (1997), we do not accept the null of weak instruments.
“Hence, following the rule of thumb suggested by Staiger and Stock (1997), we do not accept the null of weak instruments.”
From Fertility Transitions in Developing Countries: Convergence, Timing, and Causes (2019) · cites this paper as Staiger and Stock (1997)
Cited by
Sorted by citations
Initial conditions and moment restrictions in dynamic panel data models
Blundell, R., & Bond, S. (1998) · Journal of Econometrics · doi:10.1016/s0304-4076(98)00009-8 · Cited by 22,571 · see citing works
Bowden, J., Davey Smith, G., & Burgess, S. (2015) · International Journal of Epidemiology · doi:10.1093/ije/dyv080 · Cited by 9,816 · see citing works
Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
Burgess, S., Butterworth, A., & Thompson, S. G. (2013) · Genetic Epidemiology · doi:10.1002/gepi.21758 · Cited by 6,050 · see citing works
Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
Davies, N. M., Holmes, M. V., & Davey Smith, G. (2018) · BMJ · doi:10.1136/bmj.k601 · Cited by 4,404 · see citing works
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
Lawlor, D. A., Harbord, R. M., Sterne, J. A. C., Timpson, N., & Davey Smith, G. (2008) · Statistics in Medicine · doi:10.1002/sim.3034 · Cited by 4,618 · see citing works
Avoiding bias from weak instruments in Mendelian randomization studies
Burgess, S., Thompson, S. G., & CRP CHD Genetics Collaboration (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr036 · Cited by 3,952 · see citing works
Financial literacy and stock market participation
van Rooij, M., Lusardi, A., & Alessie, R. (2011) · Journal of Financial Economics · doi:10.1016/j.jfineco.2011.03.006 · Cited by 3,554 · see citing works
Using Heteroscedasticity to Identify and Estimate Mismeasured and Endogenous Regressor Models
Lewbel, A. (2012) · Journal of Business & Economic Statistics · doi:10.1080/07350015.2012.643126 · Cited by 2,712 · see citing works
Economic Shocks and Civil Conflict: An Instrumental Variables Approach
Miguel, E., Satyanath, S., & Sergenti, E. (2004) · Journal of Political Economy · doi:10.1086/421174 · Cited by 2,460 · see citing works
Angrist, J. D., & Krueger, A. B. (2001) · Journal of Economic Perspectives · doi:10.1257/jep.15.4.69 · Cited by 2,355 · see citing works
The Effect of Education on Crime: Evidence from Prison Inmates, Arrests, and Self-Reports
Lochner, L., & Moretti, E. (2004) · American Economic Review · doi:10.1257/000282804322970751 · Cited by 2,032 · see citing works
Machine Learning: An Applied Econometric Approach
Mullainathan, S., & Spiess, J. (2017) · Journal of Economic Perspectives · doi:10.1257/jep.31.2.87 · Cited by 1,989 · see citing works
Testing for Weak Instruments in Linear IV Regression
Stock, J., & Yogo, M. (2002) · doi:10.3386/t0284 · Cited by 1,842 · see citing works
Self-citationBias due to participant overlap in two‐sample Mendelian randomization
Burgess, S., Davies, N. M., & Thompson, S. G. (2016) · Genetic Epidemiology · doi:10.1002/gepi.21998 · Cited by 1,624 · see citing works
Using multiple genetic variants as instrumental variables for modifiable risk factors
Palmer, T. M., Lawlor, D. A., Harbord, R. M., Sheehan, N. A., Tobias, J. H., Timpson, N. J., Smith, G. D., & Sterne, J. A. (2012) · Statistical Methods in Medical Research · doi:10.1177/0962280210394459 · Cited by 1,289 · see citing works
Burgess, S., Dudbridge, F., & Thompson, S. G. (2016) · Statistics in Medicine · doi:10.1002/sim.6835 · Cited by 1,153 · see citing works
The Relationship Between Education and Adult Mortality in the United States
Lleras-Muney, A. (2005) · Review of Economic Studies · doi:10.1111/0034-6527.00329 · Cited by 1,282 · see citing works
Vimaleswaran, K. S., Berry, D. J., Lu, C., Tikkanen, E., Pilz, S., Hiraki, L. T., Cooper, J. D., Dastani, Z., Li, R., Houston, D. K., et al. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001383 · Cited by 1,046 · see citing works
Determinants of generalized trust: a cross-country comparison
Bjørnskov, C. (2007) · Public Choice · doi:10.1007/s11127-006-9069-1 · Cited by 969 · see citing works
A Conditional Likelihood Ratio Test for Structural Models
Moreira, M. J. (2003) · Econometrica · doi:10.1111/1468-0262.00438 · Cited by 796 · see citing works
Platform competition: Strategic trade‐offs in platform markets
Cennamo, C., & Santalo, J. (2013) · Strategic Management Journal · doi:10.1002/smj.2066 · Cited by 780 · see citing works
Neighborhood Effects on the Long-Term Well-Being of Low-Income Adults
Ludwig, J., Duncan, G. J., Gennetian, L. A., Katz, L. F., Kessler, R. C., Kling, J. R., & Sanbonmatsu, L. (2012) · Science · doi:10.1126/science.1224648 · Cited by 747 · see citing works
C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC) (2011) · BMJ · doi:10.1136/bmj.d548 · Cited by 642 · see citing works
The effect of informal care on work and wages
Van Houtven, C. H., Coe, N. B., & Skira, M. M. (2013) · Journal of Health Economics · doi:10.1016/j.jhealeco.2012.10.006 · Cited by 479 · see citing works
Instrumental Variables: Application and Limitations
Martens, E. P., Pestman, W. R., de Boer, A., Belitser, S. V., & Klungel, O. H. (2006) · Epidemiology · doi:10.1097/01.ede.0000215160.88317.cb · Cited by 464 · see citing works
Use of allele scores as instrumental variables for Mendelian randomization
Burgess, S., & Thompson, S. G. (2013) · International Journal of Epidemiology · doi:10.1093/ije/dyt093 · Cited by 452 · see citing works
Bias in causal estimates from Mendelian randomization studies with weak instruments
Burgess, S., & Thompson, S. G. (2011) · Statistics in Medicine · doi:10.1002/sim.4197 · Cited by 421 · see citing works
Bound, J., & Turner, S. (2002) · Journal of Labor Economics · doi:10.1086/342012 · Cited by 374 · see citing works
Land tenure and investment incentives: evidence from West Africa
Fenske, J. (2011) · Journal of Development Economics · doi:10.1016/j.jdeveco.2010.05.001 · Cited by 369 · see citing works
Does education cause better health? A panel data analysis using school reforms for identification
Arendt, J. N. (2005) · Economics of Education Review · doi:10.1016/j.econedurev.2004.04.008 · Cited by 359 · see citing works
Electricity provision and industrial development: evidence from India
Rud, J. P. (2012) · Journal of Development Economics · doi:10.1016/j.jdeveco.2011.06.010 · Cited by 318 · see citing works
Kyoto and the carbon footprint of nations
Aichele, R., & Felbermayr, G. (2012) · Journal of Environmental Economics and Management · doi:10.1016/j.jeem.2011.10.005 · Cited by 329 · see citing works
Timpson, N. J., Nordestgaard, B. G., Harbord, R. M., Zacho, J., Frayling, T. M., Tybjærg-Hansen, A., & Davey Smith, G. (2011) · International Journal of Obesity · doi:10.1038/ijo.2010.137 · Cited by 310 · see citing works
The Long‐Run Educational Cost of World War II
Ichino, A., & Winter‐Ebmer, R. (2004) · Journal of Labor Economics · doi:10.1086/380403 · Cited by 307 · see citing works
Education and myopia: assessing the direction of causality by mendelian randomisation
Mountjoy, E., Davies, N. M., Plotnikov, D., Smith, G. D., Rodriguez, S., Williams, C. E., Guggenheim, J. A., & Atan, D. (2018) · BMJ · doi:10.1136/bmj.k2022 · Cited by 299 · see citing works
Johnson, M. L., Crown, W., Martin, B. C., Dormuth, C. R., & Siebert, U. (2009) · Value in Health · doi:10.1111/j.1524-4733.2009.00602.x · Cited by 285 · see citing works
Towards Universal Health Coverage: An Evaluation of Rwanda Mutuelles in Its First Eight Years
Lu, C., Chin, B., Lewandowski, J. L., Basinga, P., Hirschhorn, L. R., Hill, K., Murray, M., & Binagwaho, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039282 · Cited by 263 · see citing works
Freshwater availability and water fetching distance affect child health in sub-Saharan Africa
Pickering, A. J., & Davis, J. (2012) · Environmental Science & Technology · doi:10.1021/es203177v · Cited by 264 · see citing works
The political economy of financial development
Girma, S., & Shortland, A. (2007) · Oxford Economic Papers · doi:10.1093/oep/gpm040 · Cited by 203 · see citing works
Richmond, R. C., Davey Smith, G., Ness, A. R., den Hoed, M., McMahon, G., & Timpson, N. J. (2014) · PLoS Medicine · doi:10.1371/journal.pmed.1001618 · Cited by 167 · see citing works
Rassen, J. A., Brookhart, M. A., Glynn, R. J., Mittleman, M. A., & Schneeweiss, S. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2008.12.005 · Cited by 164 · see citing works
On the Use of the Lasso for Instrumental Variables Estimation with Some Invalid Instruments
Windmeijer, F., Farbmacher, H., Davies, N., & Davey Smith, G. (2019) · Journal of the American Statistical Association · doi:10.1080/01621459.2018.1498346 · Cited by 144 · see citing works
The many weak instruments problem and Mendelian randomization
Davies, N. M., von Hinke Kessler Scholder, S., Farbmacher, H., Burgess, S., Windmeijer, F., & Smith, G. D. (2015) · Statistics in Medicine · doi:10.1002/sim.6358 · Cited by 140 · see citing works
Outcomes of primary care delivery by nurse practitioners: Utilization, cost, and quality of care
Liu, C., Hebert, P. L., Douglas, J. H., Neely, E. L., Sulc, C. A., Reddy, A., Sales, A. E., & Wong, E. S. (2020) · Health Services Research · doi:10.1111/1475-6773.13246 · Cited by 121 · see citing works
Humphreys, K., Blodgett, J. C., & Wagner, T. H. (2014) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.12557 · Cited by 116 · see citing works
Social Science Methods for Twins Data: Integrating Causality, Endowments, and Heritability
Kohler, H.-P., Behrman, J. R., & Schnittker, J. (2011) · Biodemography and Social Biology · doi:10.1080/19485565.2011.580619 · Cited by 116 · see citing works
Personalized pricing and price fairness
Richards, T. J., Liaukonyte, J., & Streletskaya, N. A. (2016) · International Journal of Industrial Organization · doi:10.1016/j.ijindorg.2015.11.004 · Cited by 99 · see citing works
Howard, R., Chao, G. F., Yang, J., Thumma, J., Chhabra, K., Arterburn, D. E., Ryan, A., Telem, D. A., & Dimick, J. B. (2021) · JAMA Surgery · doi:10.1001/jamasurg.2021.4981 · Cited by 94 · see citing works
Employment, Wages, and Voter Turnout
Charles, K. K., & Stephens, M. (2013) · American Economic Journal: Applied Economics · doi:10.1257/app.5.4.111 · Cited by 93 · see citing works
Climate change, agricultural production and civil conflict: evidence from the Philippines
Crost, B., Duquennois, C., Felter, J. H., & Rees, D. I. (2018) · Journal of Environmental Economics and Management · doi:10.1016/j.jeem.2018.01.005 · Cited by 91 · see citing works
Burgess, S., & Thompson, S. G. (2012) · Statistics in Medicine · doi:10.1002/sim.4498 · Cited by 87 · see citing works
Vermeulen, J. M., Wootton, R. E., Treur, J. L., Sallis, H. M., Jones, H. J., Zammit, S., van den Brink, W., Goodwin, G. M., de Haan, L., & Munafò, M. R. (2021) · The British Journal of Psychiatry · doi:10.1192/bjp.2019.202 · Cited by 78 · see citing works
Loyle, C. E., & Appel, B. J. (2017) · International Studies Quarterly · doi:10.1093/isq/sqx045 · Cited by 78 · see citing works
A weak instrument F-test in linear IV models with multiple endogenous variables
Sanderson, E., & Windmeijer, F. (2026) · doi:10.1920/wp.cem.2015.3115 · Cited by 72 · see citing works
Fang, S., Yarmolinsky, J., Gill, D., Bull, C. J., Perks, C. M., the PRACTICAL Consortium, Davey Smith, G., Gaunt, T. R., & Richardson, T. G. (2023) · PLOS Medicine · doi:10.1371/journal.pmed.1003988 · Cited by 55 · see citing works
An analysis of the pricing of traits in the U.S. corn seed market
Shi, G., Chavas, J.-P., & Stiegert, K. (2010) · American Journal of Agricultural Economics · doi:10.1093/ajae/aaq063 · Cited by 52 · see citing works
Taylor, P. N., Richmond, R., Davies, N., Sayers, A., Stevenson, K., Woltersdorf, W., Taylor, A., Groom, A., Northstone, K., Ring, S., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-3505 · Cited by 48 · see citing works
Some like it Healthy: Demand for functional and conventional yogurts in the italian market
Bonannoxs, A. (2012) · Agribusiness · doi:10.1002/agr.20288 · Cited by 33 · see citing works
Efficient Tests Under a Weak Convergence Assumption
(2011) · Econometrica · doi:10.3982/ecta7793 · Cited by 30 · see citing works
The Role of Foreign Direct Investment in Post-Conflict Economic Recovery and Peace-Building
Bak, D., Lee, H., & Biglaiser, G. (2024) · Foreign Policy Analysis · doi:10.1093/fpa/orae032 · Cited by 8 · see citing works
Wu, C., Pu, Q., Zou, Y., Jin, J., Lei, Y., Hu, Y., Chen, Z., & Yu, L. (2025) · Scientific Reports · doi:10.1038/s41598-025-15525-4 · Cited by 3 · see citing works
Liu, Z., Zhang, Y., Graham, S., Pique-Regi, R., Dong, X. C., Chen, Y. E., Willer, C., & Liu, W. (2019) · doi:10.1101/657734 · Cited by 250 · see citing works
Fertility Transitions in Developing Countries: Convergence, Timing, and Causes
Papagni, E. (2019) · SSRN Electronic Journal · doi:10.2139/ssrn.3522996 · Cited by 1 · see citing works
- Authors
- Staiger, D., & Stock, J. H.
- Affiliations
- Dartmouth College (US)
- National Bureau of Economic Research (US)
- ORCID
- Staiger, Douglas
- Venue
- Econometrica
- Publisher
- JSTOR
- Published
- 1997-05
- Volume
- 65
- Issue
- 3
- Pages
- 557
- ISSN
- 0012-9682 (ISSN-L)
- OpenAlex
- W2165144879
- Cited by
- 7,081
- References
- 0
- Citations by year
- 2026: 458 · 2025: 398 · 2024: 405 · 2023: 329 · 2022: 395 · 2021: 363 · 2020: 347 · 2019: 362 · 2018: 329 · 2017: 348 · 2016: 365 · 2015: 311 · 2014: 304 · 2013: 283 · 2012: 305
- FWCI
- 34.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Econometrica (publishedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Spatial and Panel Data Analysis
- Social Sciences › Economics, Econometrics and Finance › General Economics, Econometrics and Finance › Monetary Policy and Economic Impact
- Keywords
- weak instruments, instrumental variable regression, asymptotic distribution, two-stage least squares, limited information maximum likelihood, endogeneity, returns to education, t-statistic, partial correlation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review