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The Ability of Nutrition to Mitigate Epigenetic Drift: A Novel Look at Regulating Gene Expression

D. PALMER, Raymond, PAPA, Veronica, VACCAREZZA, Mauro·2021·Journal of Nutritional Science and Vitaminology
DOI 10.3177/jnsv.67.359
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  • Tier 1 interventions such as exercise, fasting mimetics like metformin or rapamycin, fasting, and an epigenetic diet remain insufficient to slow down the damaging effects of aging.

    “Tier 1 interventions such as staying fit, 1 , 2 taking pills such as fasting mimetics like metformin or rapamycin, 3 , 4 , 5 fasting, 3 , 6 , 7 and an epigenetic diet 8 remain insufficient to slow down the damaging effects of aging.”

    From Three Tiers to biological escape velocity: The quest to outwit aging (2022) · cites this paper as [8]

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  1. 1) Weinhold B. 2006. Epigenetics: the science of change. Environ Health Perspect 114(3): A160. · DOI
  2. 3) Madreiter-Sokolowski CT, Sokolowski AA, Waldeck-Weiermair M, Malli R, Graier WF. 2018. Targeting mitochondria to counteract age-related cellular dysfunction. Genes (Basel) 9(3): 165. · DOI
  3. 4) Altun G, Loring JF, Laurent LC. 2010. DNA methylation in embryonic stem cells. J Cell Biochem 109(1): 1-6. · DOI
  4. 5) Bird A. 2002. DNA methylation patterns and epigenetic memory. Genes Dev 16(1): 6-21. · DOI · Paper page
  5. 6) Jenuwein T, Allis CD. 2001. Translating the histone code. Science 293(5532): 1074-1080. · DOI · Paper page
  6. 7) Sparmann A, Van Lohuizen M. 2006. Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6(11): 846-856. · DOI
  7. 9) Moosavi A, Ardekani AM. 2016. Role of epigenetics in biology and human diseases. Iran Biomed J 20(5): 246-258.
  8. 10) Tzika E, Dreker T, Imhof A. 2018. Epigenetics and metabolism in health and disease. Front Genet 9: 361. · DOI
  9. 11) Xie K, Ryan DP, Pearson BL, Henzel KS, Neff F, Vidal RO, Hennion M, Lehmann I, Schleif M, Schröder S, Adler T, Rathkolb B, Rozman J, Schütz AL, Prehn C, Mickael ME, Weiergräber M, Adamski J, Busch DH, Ehninger G, Matynia A, Jackson WS, Wolf E, Fuchs H, Gailus-Durner V, Bonn S, de Angelis MH, Ehninger D. 2018. Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice. Proc Natl Acad Sci USA 115(10): E2348-E2357. · DOI
  10. 12) Lee J-H, Kim EW, Croteau DL, Bohr VA. 2020. Heterochromatin: an epigenetic point of view in aging. Exp Mol Med 52(9): 1466-1474. · DOI
  11. 13) Gadecka A, Bielak-Zmijewska A. 2019. Slowing down ageing: The role of nutrients and microbiota in modulation of the epigenome. Nutrients 11(6): 1251. · DOI
  12. 14) Carrozza MJ, Utley RT, Workman JL, Côté J. 2003. The diverse functions of histone acetyltransferase complexes. Trends Genet 19(6): 321-329. · DOI · Paper page
  13. 15) Hull EE, Montgomery MR, Leyva KJ. 2016. HDAC inhibitors as epigenetic regulators of the immune system: Impacts on cancer therapy and inflammatory diseases. Biomed Res Int 2016: 8797206. · DOI
  14. 16) Huber MD, Gerace L. 2007. The size-wise nucleus: Nuclear volume control in eukaryotes. J Cell Biol 179(4): 583-584. · DOI
  15. 17) Lammerding J. 2011. Mechanics of the nucleus. Compr Physiol 1(2): 783-807. · DOI
  16. 18) Landecker H. 2011. Food as exposure: Nutritional epigenetics and the new metabolism. Biosocieties 6(2): 167-194. · DOI
  17. 21) Tsurumi A, Li WX. 2012. Global heterochromatin loss: A unifying theory of aging? Epigenetics 7(7): 680-688. · DOI · Paper page
  18. 22) Haithcock E, Dayani Y, Neufeld E, Zahand AJ, Feinstein N, Mattout A, Gruenbaum Y, Liu J. 2005. Age-related changes of nuclear architecture in Caenorhabditis elegans. Proc Natl Acad Sci USA 102(46): 16690-16695. · DOI
  19. 23) Scaffidi P, Misteli T. 2006. Lamin A-dependent nuclear defects in human aging. Science 312(5776): 1059-1063. · DOI · Paper page
  20. 24) Hu Z, Chen K, Xia Z, Chavez M, Pal S, Seol JH, Chen CC, Li W, Tyler JK. 2014. Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging. Genes Dev 28(4): 396-408. · DOI
  21. 27) Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, Kennedy BK, Kaeberlein M, Berger SL. 2014. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. Cell Metab 19(6): 952-966. · DOI · Paper page
  22. 29) McCormick MA, Delaney JR, Tsuchiya M, Tsuchiyama S, Shemorry A, Sim S, Chou AC, Ahmed U, Carr D, Murakami CJ, Schleit J, Sutphin GL, Wasko BM, Bennett CF, Wang AM, Olsen B, Beyer RP, Bammler TK, Prunkard D, Johnson SC, Pennypacker JK, An E, Anies A, Castanza AS, Choi E, Dang N, Enerio S, Fletcher M, Fox L, Goswami S, Higgins SA, Holmberg MA, Hu D, Hui J, Jelic M, Jeong KS, Johnston E, Kerr EO, Kim J, Kim D, Kirkland K, Klum S, Kotireddy S, Liao E, Lim M, Lin MS, Lo WC, Lockshon D, Miller HA, Moller RM, Muller B, Oakes J, Pak DN, Peng ZJ, Pham KM, Pollard TG, Pradeep P, Pruett D, Rai D, Robison B, Rodriguez AA, Ros B, Sage M, Singh MK, Smith ED, Snead K, Solanky A, Spector BL, Steffen KK, Tchao BN, Ting MK, Vander Wende H, Wang D, Welton KL, Westman EA, Brem RB, Liu XG, Suh Y, Zhou Z, Kaeberlein M, Kennedy BK. 2015. A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging. Cell Metab 22(5): 895-906. · DOI
  23. 30) Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, Rossi DJ. 2013. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell 12(4): 413-425. · DOI · Paper page
  24. 32) Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, Klotzle B, Bibikova M, Fan JB, Gao Y, Deconde R, Chen M, Rajapakse I, Friend S, Ideker T, Zhang K. 2013. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell 49(2): 359-367. · DOI · Paper page
  25. 33) Ek WE, Tobi EW, Ahsan M, Lampa E, Ponzi E, Kyrtopoulos SA, Georgiadis P, Lumey LH, Heijmans BT, Botsivali M, Bergdahl IA, Karlsson T, Rask-Andersen M, Palli D, Ingelsson E, Hedman ÅK, Nilsson LM, Vineis P, Lind L, Flanagan JM, Johansson Å. 2017. Tea and coffee consumption in relation to DNA methylation in four European cohorts. Hum Mol Genet 26(16): 3221-3231. · DOI
  26. 34) Persky V, Setchell KDR, Barnes S. 1994. Soy intake and cancer risk: A review of the in vitro and in vivo data. Nutr Cancer 21(2): 113-131. · DOI
  27. 35) Singh R, Akhtar N, Haqqi TM. 2010. Green tea polyphenol epigallocatechi3-gallate: Inflammation and arthritis. Life Sci 86(25-26): 907-918. · DOI
  28. 36) Guo Y, Wu R, Gaspar JM, Sargsyan D, Su ZY, Zhang C, Gao L, Cheng D, Li W, Wang C, Yin R, Fang M, Verzi MP, Hart RP, Kong AN. 2018. DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice. Carcinogenesis 39(5): 669-680. · DOI
  29. 37) Antequera F. 2003. Structure, function and evolution of CpG island promoters. Cell Mol Life Sci 60(8): 1647-1658. · DOI
  30. 38) Link A, Balaguer F, Shen Y, Lozano JJ, Leung HC, Boland CR, Goel A. 2013. Curcumin modulates DNA methylation in colorectal cancer cells. PLoS One 8(2): e57709. · DOI
  31. 39) Boyanapalli SSS, Kong ANT. 2015. “Curcumin, the king of spices”: Epigenetic regulatory mechanisms in the prevention of cancer, neurological, and inflammatory diseases. Curr Pharmacol Reports 1(2): 129-139. · DOI
  32. 40) Atwell LL, Zhang Z, Mori M, Farris P, Vetto JT, Naik AM, Oh KY, Thuillier P, Ho E, Shannon J. 2015. Sulforaphane bioavailability and chemopreventive activity in women scheduled for breast biopsy. Cancer Prev Res 8(12): 1184-1191. · DOI
  33. 41) Li Y, Saldanha SN, Tollefsbol TO. 2014. Impact of epigenetic dietary compounds on transgenerational prevention of human diseases. AAPS J 16(1): 27-36. · DOI
  34. 43) McKay JA, Williams EA, Mathers JC. 2004. Folate and DNA methylation during in utero development and aging. Biochem Soc Trans 32: 1006-1007. · DOI
  35. 44) Wang G, Hu FB, Mistry KB, Zhang C, Ren F, Huo Y, Paige D, Bartell T, Hong X, Caruso D, Ji Z, Chen Z, Ji Y, Pearson C, Ji H, Zuckerman B, Cheng TL, Wang X. 2016. Association between maternal prepregnancy body mass index and plasma folate concentrations with child metabolic health. JAMA Pediatr 170(8): 160845. · DOI · Paper page
  36. 46) Park LK, Friso S, Choi SW. 2012. Nutritional influences on epigenetics and age-related disease. Proc Nutr Soc 71: 75-83. · DOI
  37. 47) Waterland RA, Travisano M, Tahiliani KG, Rached MT, Mirza S. 2008. Methyl donor supplementation prevents transgenerational amplification of obesity. Int J Obes 32(9): 1373-1379. · DOI
  38. 48) Speckmann B, Grune T. 2015. Epigenetic effects of selenium and their implications for health. Epigenetics 10(3): 179-190. · DOI
  39. 49) Li Y, Liu L, Andrews LG, Tollefsbol TO. 2009. Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer 125(2): 286-296. · DOI
  40. 50) Hornsby PJ. 2007. Telomerase and the aging process. Exp Gerontol 42(7): 575-581. · DOI
  41. 51) Shammas MA. 2011. Telomeres, lifestyle, cancer, and aging. Curr Opin Clin Nutr Metab Care 14(1): 28-34. · DOI
  42. 52) John EM, Stern MC, Sinha R, Koo J. 2011. Meat consumption, cooking practices, meat mutagens and risk of prostate cancer. Nutr Cancer 63(4): 525. · DOI
  43. 53) Uribarri J, Woodruff S, Goodman S, Cai W, Chen X, Pyzik R, Yong A, Striker GE, Vlassara H. 2010. Advanced glycation end products in foods and a practical guide to their reduction in the diet. J Am Diet Assoc 110(6): 911. · DOI · Paper page
  44. 54) Chen JH, Lin X, Bu C, Zhang X. 2018. Role of advanced glycation end products in mobility and considerations in possible dietary and nutritional intervention strategies. Nutr Metab 15(1): 72. · DOI
  45. 56) Catterson JH, Khericha M, Dyson MC, Vincent AJ, Callard R, Haveron SM, Rajasingam A, Ahmad M, Partridge L. 2018. Short-term, intermittent fasting induces long-lasting gut health and TOR-independent lifespan extension. Curr Biol 28(11): 1714-1724.e4. · DOI · Paper page
  46. 57) Zeisel SH. 2017. Choline, other methyl-donors and epigenetics. Nutrients 9(5): 445. · DOI
  47. 58) Bekdash RA. 2016. Choline and the brain: An epigenetic perspective. In: Advances in Neurobiology, Vol 12, p 381-399. Springer, New York. · DOI
  48. 59) Mori MA, Raghavan P, Thomou T, Boucher J, Robida-Stubbs S, Macotela Y, Russell SJ, Kirkland JL, Blackwell TK, Kahn CR. 2012. Role of microRNA processing in adipose tissue in stress defense and longevity. Cell Metab 16(3): 336-347. · DOI
  49. 60) Curley JP, Mashoodh R, Champagne FA. 2011. Epigenetics and the origins of paternal effects. Horm Behav 59(3): 306-314. · DOI
  50. 61) Field AE, Robertson NA, Wang T, Havas A, Ideker T, Adams PD. 2018. DNA methylation clocks in aging: Categories, causes, and consequences. Mol Cell 71(6): 882-895. · DOI
  51. 63) Horvath S. 2013. DNA methylation age of human tissues and cell types. Genome Biol 14(10): R115. · DOI · Paper page
  52. 65) Alegría-Torres JA, Baccarelli A, Bollati V. 2011. Epigenetics and lifestyle. Epigenomics 3(3): 267-277. · DOI · Paper page
  53. 66) Tsai PC, Glastonbury CA, Eliot MN, Bollepalli S, Yet I, Castillo-Fernandez JE, Carnero-Montoro E, Hardiman T, Martin TC, Vickers A, Mangino M, Ward K, Pietiläinen KH, Deloukas P, Spector TD, Viñuela A, Loucks EB, Ollikainen M, Kelsey KT, Small KS, Bell JT. 2018. Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health. Clin Epigenetics 10(1): 126. · DOI
  54. 67) Zilfou JT, Lowe SW. 2009. Tumor suppressive functions of p53. Cold Spring Harb Perspect Biol 1(5): a001883. · DOI
  55. 68) Ozaki T, Nakagawara A. 2011. Role of p53 in cell death and human cancers. Cancers (Basel) 3(1): 994-1013. · DOI
  56. 69) Jackson M, Marks L, May GHW, Wilson JB. 2018. The genetic basis of disease. Essays Biochem 62(5): 643-723. · DOI · Paper page
  57. 70) Kuro-o M. 2011. Klotho and the aging process. Korean J Intern Med 26(2): 113-122. · DOI
  58. 71) Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, Ohyama Y, Kurabayashi M, Kaname T, Kume E, Iwasaki H, Iida A, Shiraki-Iida T, Nishikawa S, Nagai R, Nabeshima YI. 1997. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390(6655): 45-51. · DOI · Paper page
  59. 72) Chen C Di, Zeldich E, Li Y, Yuste A, Abraham CR. 2018. Activation of the anti-aging and cognition-enhancing gene klotho by CRISPR-dCas9 transcriptional effector complex. J Mol Neurosci 64(2): 175-184. · DOI
  60. 73) Hardy TM, Tollefsbol TO. 2011. Epigenetic diet: Impact on the epigenome and cancer. Epigenomics 3(4): 503-518. · DOI
  61. 74) Bacalini MG, Friso S, Olivieri F, Pirazzini C, Giuliani C, Capri M, Santoro A, Franceschi C, Garagnani P. 2014. Present and future of anti-ageing epigenetic diets. Mech Ageing Dev 136-137: 101-115. · DOI
  62. 76) Deaton AM, Bird A. 2011. CpG islands and the regulation of transcription. Genes Dev 25(10): 1010-1022. · DOI · Paper page
  63. 77) Rando TA, Chang HY. 2012. Aging, rejuvenation, and epigenetic reprogramming: Resetting the aging clock. Cell 148(1-2): 46-57. · DOI · Paper page
  64. 78) Vaiserman AM. 2008. Epigenetic engineering and its possible role in anti-aging intervention. Rejuvenation Res 11(1): 39-42. · DOI

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Metadata

Authors
D. PALMER, R., PAPA, V., & VACCAREZZA, M.
Affiliations
  • Helium-3 Biotech
  • Department of Motor Sciences and Wellness, University of Naples “Parthenope”
  • Curtin Medical School, Faculty of Health Sciences, Curtin Health Innovation Research Institute (CHIRI), Curtin University
Venue
Journal of Nutritional Science and Vitaminology
Publisher
Center for Academic Publications Japan
Published
2021-12-31
Volume
67
Issue
6
Pages
359-365
ISSN
  • 0301-4800
  • 1881-7742
DOI
10.3177/jnsv.67.359
Cited by
3
References
14
Language
en

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