Epigenomics as potential tools for enhancing magnitude of breeding approaches for developing climate resilient chickpea
Open accessAbstract
Epigenomics has become a significant research interest at a time when rapid environmental changes are occurring. Epigenetic mechanisms mainly result from systems like DNA methylation, histone modification, and RNA interference. Epigenetic mechanisms are gaining importance in classical genetics, developmental biology, molecular biology, cancer biology, epidemiology, and evolution. Epigenetic mechanisms play important role in the action and interaction of plant genes during development, and also have an impact on classical plant breeding programs, inclusive of novel variation, single plant heritability, hybrid vigor, plant-environment interactions, stress tolerance, and performance stability. The epigenetics and epigenomics may be significant for crop adaptability and pliability to ambient alterations, directing to the creation of stout climate-resilient elegant crop cultivars. In this review, we have summarized recent progress made in understanding the epigenetic mechanisms in plant responses to biotic and abiotic stresses and have also tried to provide the ways for the efficient utilization of epigenomic mechanisms in developing climate-resilient crop cultivars, especially in chickpea, and other legume crops.
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DNA methylation and histone changes significantly enhance stress responses in leguminous crops such as Cicer arietinum.
“Modifications like DNA methylation and histone changes significantly enhance stress responses in leguminous crops, such as Cicer arietinum (Chandana et al., 2022).”
From Emerging applications of gene editing technologies for the development of climate-resilient crops (2025) · cites this paper as Chandana et al., 2022
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Gupta, A., Sharma, T., Singh, S. P., Bhardwaj, A., Srivastava, D., & Kumar, R. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1053810 · Cited by 90 · see citing works
Emerging applications of gene editing technologies for the development of climate-resilient crops
Chavhan, R. L., Jaybhaye, S. G., Hinge, V. R., Deshmukh, A. S., Shaikh, U. S., Jadhav, P. K., Kadam, U. S., & Hong, J. C. (2025) · Frontiers in Genome Editing · doi:10.3389/fgeed.2025.1524767 · Cited by 43 · see citing works
“Modi fi cations like DNA methylation and histone changes signi fi cantly enhance stress responses in leguminous crops, such as Cicer arietinum (Chandana et al., 2022).”
Zang, J., Jin, S., Zhang, S., Li, Q., Mu, Y., Li, Z., Li, S., Wang, X., Su, Y., & Jiang, D. (2023) · Plant Methods · doi:10.1186/s13007-023-01012-2 · Cited by 34 · see citing works
Singh, C., Kumar, R., Sehgal, H., Bhati, S., Singhal, T., Gayacharan, Nimmy, M. S., Yadav, R., Gupta, S. K., Abdallah, N. A., et al. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1085024 · Cited by 26 · see citing works
Mahto, R. K., S., C. B., Singh, R. K., Kumar, A., Kumar, S., Yadav, R., Dey, D., Hamwieh, A., & Kumar, R. (2025) · Frontiers in Plant Science · doi:10.3389/fpls.2025.1621191 · Cited by 10 · see citing works
Plant Breeding Using the CRISPR-Cas9 System for Food Security and Facing Climate Change
Ambika, A., Bhati, S., & Kumar, R. (2024) · Interdisciplinary biotechnological advances · doi:10.1007/978-981-99-9338-3_6 · Cited by 11 · see citing works
Abiotic Stress and Mechanisms of Stress Tolerance in Vegetable Crops
Zhan, X., & Zhu, Y. (2025) · Springer eBooks · doi:10.1007/978-981-96-0169-1_8 · Cited by 9 · see citing works
Yadav, R., Jaiswal, S., Singhal, T., Mahto, R. K., Verma, S. B., Yadav, R. K., & Kumar, R. (2023) · Frontiers in Genome Editing · doi:10.3389/fgeed.2023.1203485 · Cited by 7 · see citing works
Awaly, S. B. H., Abdellatif, R. I., Radwan, K. H., Abdelsattar, M., Alsamman, A. M., & Osman, N. H. (2025) · South African Journal of Botany · doi:10.1016/j.sajb.2025.02.039 · Cited by 3 · see citing works
Omics Approaches and Endophyte-Related Hormones for Promoting Host Plant Growth
Brar, B., Joshi, S., Bala, K., Kumar, R., Prasad, M., Manuja, A., Jabborova, D., Duhan, J. S., & Saharan, B. S. (2025) · Microorganisms for sustainability · doi:10.1007/978-981-96-4100-0_1 · Cited by 3 · see citing works
Unveiling the epigenetic landscape of plants using flow cytometry approach
Jyoti, T. P., Chandel, S., & Singh, R. (2024) · Cytometry Part A · doi:10.1002/cyto.a.24834 · Cited by 3 · see citing works
DISEASES OF WILD APPLE SIVERS IN THE DZUNGARIAN AND TRANS-ILI ALATAU
Солтанбеков, С., Исина, Ж. М., Dzhumanova, Z. K., & Seisenova, A. A. (2024) · Bulletin of Korkyt Ata Kyzylorda University · doi:10.52081/bkaku.2024.v68.i1.142 · Cited by 2 · see citing works
Approaches to Enhance Abiotic and Biotic Stress Tolerance in Leguminous Crops and Microgreens
Sharma, P., & Kumari, A. (2025) · Springer eBooks · doi:10.1007/978-3-031-75678-8_9 · Cited by 2 · see citing works
Suruthi, G. S., Anand, A. V., Rajesh, M., Begum, T. N., Begum, S. B., Priya, A., Sampathkumar, P., & Robert, A. A. (2025) · CABI climate change series. · doi:10.1079/9781800626102.0002 · Cited by 1 · see citing works
A Situational Approach to Training and Development.
Schachhuber, D. (1980) · Lifelong Learning: The Adult Years · Cited by 1 · see citing works
Temirzhanova, A., Rustem, A., Ateikhan, B., & Titanov, Z. Е. (2024) · Bulletin of Korkyt Ata Kyzylorda University · doi:10.52081/bkaku.2024.v68.i1.138
Plant Epigenetic Regulation Under Stress Conditions: Machinery and Applications
Cedillo-Jiménez, C. A., Aranda, A. L. V., & Guevara-González, R. G. (2025) · CABI climate change series. · doi:10.1079/9781800626102.0024
Plant Single-Cell Epigenomics: Updated Methods and Current Applications
Suruthi, G. S., Anand, A. V., Rajesh, M., Gowtham, P., Begum, T. N., Haniff, S. M., Sampathkumar, P., & Robert, A. A. (2025) · CABI climate change series. · doi:10.1079/9781800626102.0005
Zang, J., Jin, S., Zhang, S., Li, Q., Mu, Y., Li, Z., Li, S., Wang, X., Su, Y., & Jiang, D. (2023) · Figshare · doi:10.6084/m9.figshare.22620817
Harnessing Epigenetics for the Breeding of Stress-Tolerant Crops
Zafar, S., Rasheed, R., Ashraf, M. A., & Khan, I. M. (2025) · IGI Global eBooks · doi:10.4018/979-8-3693-8648-4.ch012
Research gaps and future directions
Pereira, L. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33492-4.00015-2
The Multi‐Omics Opportunity to Improve Heat Adaptation in Chickpea
Jamie, C. B., Haeften, S. V., Hickey, L. T., Chenu, K., & Smith, M. R. (2026) · Food and Energy Security · doi:10.1002/fes3.70292
Yadav, S. P. S., Shivashakarappa, K., Bhandari, N., Taheri, A., & Wallace, L. T. (2026) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2026.103176
- Authors
- Chandana, B. S., Mahto, R. K., Singh, R. K., Ford, R., Vaghefi, N., Gupta, S. K., Yadav, H. K., Manohar, M., & Kumar, R.
- Affiliations
- Indian Council of Agricultural Research (IN)
- Griffith University (AU)
- The University of Melbourne (AU)
- National Institute of Plant Genome Research (IN)
- National Botanical Research Institute (IN)
- Cornell University (US)
- Corresponding author
- Kumar, Rajendra
- ORCID
- Venue
- Frontiers in Genetics
- Publisher
- Frontiers Media SA
- Published
- 2022-07-22
- Volume
- 13
- Pages
- 900253-900253
- ISSN
- 1664-8021 (ISSN-L)
- PMC
- PMC9355295
- OpenAlex
- W4286560618
- Cited by
- 23
- References
- 235
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 4 · 2023: 5
- FWCI
- 0.44
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Genetics (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- Funders
- Department of Biotechnology, Ministry of Science and Technology, India
- Department of Science and Technology, Ministry of Science and Technology, India
- Indian Council of Agricultural Research
- Griffith University
- University of Southern Queensland
- Indian Agricultural Research Institute
- CSIR-National Botanical Research Institute
- Science and Engineering Research Board
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetic and Environmental Crop Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- epigenomics, epigenetic mechanisms, chickpea, climate resilience, plant breeding, DNA methylation, histone modifications, RNA interference, stress tolerance, abiotic stress, biotic stress, heterosis, plant-environment interactions, legume crops, crop adaptability
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