Cited by 244Barrier Structure and Function StudiesRetinal Diseases and TreatmentsAngiogenesis and VEGF in Cancer

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Brain and Retinal Pericytes: Origin, Function and Role

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Trost, Andrea, Lange, Simona, Schroedl, Falk, Bruckner, Daniela, Motloch, Karolina A., Bogner, Barbara, Kaser-Eichberger, Alexandra, Strohmaier, Clemens, Runge, Christian, Aigner, Ludwig, Rivera, Francisco J., Reitsamer, Herbert A.·2016·Frontiers in Cellular Neuroscience

DOI 10.3389/fncel.2016.00020PMC PMC4740376

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Abstract

Pericytes are specialized mural cells located at the abluminal surface of capillary blood vessels, embedded within the basement membrane. In the vascular network these multifunctional cells fulfil diverse functions, which are indispensable for proper homoeostasis. They serve as microvascular stabilizers, are potential regulators of microvascular blood flow and have a central role in angiogenesis, as they for example regulate endothelial cell proliferation. Furthermore, pericytes, as part of the neurovascular unit, are a major component of the blood-retina/brain barrier. CNS pericytes are a heterogenic cell population derived from mesodermal and neuro-ectodermal germ layers acting as modulators of stromal and niche environmental properties. In addition, they display multipotent differentiation potential making them an intriguing target for regenerative therapies. Pericyte-deficiencies can be cause or consequence of many kinds of diseases. In diabetes, for instance, pericyte-loss is a severe pathological process in diabetic retinopathy (DR) with detrimental consequences for eye sight in millions of patients. In this review, we provide an overview of our current understanding of CNS pericyte origin and function, with a special focus on the retina in the healthy and diseased. Finally, we highlight the role of pericytes in de- and regenerative processes.

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RETRACTED ARTICLE: Pericyte loss influences Alzheimer-like neurodegeneration in mice
Sagare, A. P., Bell, R. D., Zhao, Z., Ma, Q., Winkler, E. A., Ramanathan, A., & Zlokovic, B. V. (2013) · Nature Communications · doi:10.1038/ncomms3932 · Cited by 589
Retracted
Retracted Article: Pericyte-mediated vasoconstriction underlies TBI-induced hypoperfusion
Dore‐Duffy, P., Wang, S. S., Mehedi, A., Katyshev, V., Cleary, K., Tapper, A., Reynolds, C. A., Ding, Y., Zhan, P., Rafols, J. A., et al. (2011) · Neurological Research · doi:10.1179/016164111x12881719352372 · Cited by 69
Retracted
Diabetic Retinopathy
Lang, G. E., Vaiser, A., Snyder, W. B., & Lynn, J. R. (2007) · Developments in ophthalmology · doi:10.1159/isbn.978-3-318-01439-6 · Cited by 5,607
A perivascular origin for mesenchymal stem cells in multiple human organs
Crisan, M., Yap, S., Casteilla, L., Chen, C.-W., Corselli, M., Park, T. S., Andriolo, G., Sun, B., Zheng, B., Zhang, L., et al. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.07.003 · Cited by 3,991 · cited 2×
“As these cells, next to pericyte markers (NG2+, CD146+, aSMA+), also expressed markers typical for MSCs, the authors suggested that MSCs may have developed from perivascular cells/pericytes (Caplan, 2008; Crisan et al., 2008).”
Background
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
Zlokovic, B. V. (2008) · Neuron · doi:10.1016/j.neuron.2008.01.003 · Cited by 3,280
Pericytes regulate the blood–brain barrier
Armulik, A., Genové, G., Mäe, M., Nisancioglu, M. H., Wallgard, E., Niaudet, C., He, L., Norlin, J., Lindblom, P., Strittmatter, K., et al. (2010) · Nature · doi:10.1038/nature09522 · Cited by 2,843
Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
Armulik, A., Genové, G., & Betsholtz, C. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.07.001 · Cited by 2,653
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
Lindahl, P., Johansson, B. R., Levéen, P., & Betsholtz, C. (1997) · Science · doi:10.1126/science.277.5323.242 · Cited by 2,226
Pericytes are required for blood–brain barrier integrity during embryogenesis
Daneman, R., Zhou, L., Kebede, A. A., & Barres, B. A. (2010) · Nature · doi:10.1038/nature09513 · Cited by 2,128
Endothelial/Pericyte Interactions
Armulik, A., Abramsson, A., & Betsholtz, C. (2005) · Circulation Research · doi:10.1161/01.res.0000182903.16652.d7 · Cited by 2,048
Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
Caplan, A. I. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21200 · Cited by 1,956
Capillary pericytes regulate cerebral blood flow in health and disease
Hall, C. N., Reynell, C., Gesslein, B., Hamilton, N. B., Mishra, A., Sutherland, B. A., O’Farrell, F. M., Buchan, A. M., Lauritzen, M., & Attwell, D. (2014) · Nature · doi:10.1038/nature13165 · Cited by 1,870
Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
Humphreys, B. D., Lin, S., Kobayashi, A., Hudson, T. E., Nowlin, B. T., Bonventre, J. V., Valerius, M. T., McMahon, A. P., & Duffield, J. S. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090517 · Cited by 1,474
Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
Bell, R. D., Winkler, E. A., Sagare, A. P., Singh, I., LaRue, B., Deane, R., & Zlokovic, B. V. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.043 · Cited by 1,448
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
Danielian, P. S., Muccino, D. R., Rowitch, D. H., Michael, S. K., & McMahon, A. P. (1998) · Current Biology · doi:10.1016/s0960-9822(07)00562-3 · Cited by 1,295
Bidirectional control of CNS capillary diameter by pericytes
Peppiatt, C. M., Howarth, C., Mobbs, P., & Attwell, D. (2006) · Nature · doi:10.1038/nature05193 · Cited by 1,150
Lack of Pericytes Leads to Endothelial Hyperplasia and Abnormal Vascular Morphogenesis
Hellström, M., Gerhardt, H., Kalén, M., Li, X., Eriksson, U., Wolburg, H., & Betsholtz, C. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.153.3.543 · Cited by 1,132
Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.Preprint
Levéen, P., Pekny, M., Gebré‐Medhin, S., Swolin, B., Larsson, E., & Betsholtz, C. (1994) · Genes & Development · doi:10.1101/gad.8.16.1875 · Cited by 1,130
Endothelial-pericyte interactions in angiogenesis
Gerhardt, H., & Betsholtz, C. (2003) · Cell and Tissue Research · doi:10.1007/s00441-003-0745-x · Cited by 1,086
Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells
Dellavalle, A., Sampaolesi, M., Tonlorenzi, R., Tagliafico, E., Sacchetti, B., Perani, L., Innocenzi, A., Gálvez, B. G., Messina, G., Roberta Morosetti, A., et al. (2007) · Nature Cell Biology · doi:10.1038/ncb1542 · Cited by 1,021
Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.Preprint
Soriano, P. M. (1994) · Genes & Development · doi:10.1101/gad.8.16.1888 · Cited by 988
Central nervous system pericytes in health and disease
Winkler, E. A., Bell, R. D., & Zlokovic, B. V. (2011) · Nature Neuroscience · doi:10.1038/nn.2946 · Cited by 962
Diabetic Retinopathy
Frank, R. N. (2003) · New England Journal of Medicine · doi:10.1056/nejmra021678 · Cited by 906
A Pericyte Origin of Spinal Cord Scar Tissue
Göritz, C., Dias, D. O., Tomilin, N., Barbacid, M., Shupliakov, O., & Frisén, J. (2011) · Science · doi:10.1126/science.1203165 · Cited by 858
Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
Yemişçi, M., Özdemir, Y., Vural, A., Can, A., Topalkara, K., & Dalkara, T. (2009) · Nature Medicine · doi:10.1038/nm.2022 · Cited by 805
Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes
Hill, R., Тонг, Л., Yuan, P., Murikinati, S. R., Gupta, S., & Grutzendler, J. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.001 · Cited by 738
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions
Klaassen, I., Noorden, C. J. F. V., & Schlingemann, R. O. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2013.02.001 · Cited by 738
All MSCs Are Pericytes?
Caplan, A. I. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.08.008 · Cited by 695
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wallPreprint
Lindblom, P., Gerhardt, H., Liebner, S., Abramsson, A., Enge, M., Hellström, M., Bäckström, G., Fredriksson, S., Landegren, U. D., Nyström, H. C., et al. (2003) · Genes & Development · doi:10.1101/gad.266803 · Cited by 674
Pericytes and the Pathogenesis of Diabetic Retinopathy
Hammes, H., Lin, J., Renner, O., Shani, M., Lundqvist, A., Betsholtz, C., Brownlee, M., & Deutsch, U. (2002) · Diabetes · doi:10.2337/diabetes.51.10.3107 · Cited by 669
The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain
Etchevers, H. C., Vincent, C., Douarin, N. M. L., & F. Couly, G. (2001) · Development · doi:10.1242/dev.128.7.1059 · Cited by 657
Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease
Halliday, M. R., Rege, S. V., Ma, Q., Zhao, Z., Miller, C. A., Winkler, E. A., & Zlokovic, B. V. (2016) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2015.44 · Cited by 649
Bone Marrow-Derived Cells Do Not Incorporate Into the Adult Growing Vasculature
Ziegelhoeffer, T., Fernández, B., Sawa Kostin, D., Heil, M., Voswinckel, R., Helisch, A., & Schaper, W. K. A. (2003) · Circulation Research · doi:10.1161/01.res.0000110419.50982.1c · Cited by 604
NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis
Özerdem, U., Grako, K. A., Dahlin‐Huppe, K., Monosov, E., & Stallcup, W. B. (2001) · Developmental Dynamics · doi:10.1002/dvdy.1200 · Cited by 592
Vascular Pericytes Express Osteogenic Potential In Vitro and In Vivo
Doherty, M. J., Ashton, B. A., Walsh, S., Beresford, J. N., Grant, M. E., & Canfield, A. E. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.5.828 · Cited by 566
Deficiency in Mural Vascular Cells Coincides with Blood–Brain Barrier Disruption in Alzheimer's Disease
Sengillo, J. D., Winkler, E. A., Walker, C. T., Sullivan, J. S., Johnson, M., & Zlokovic, B. V. (2013) · Brain Pathology · doi:10.1111/bpa.12004 · Cited by 553
PDGFRβ+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
Song, S., Ewald, A. J., Stallcup, W. B., Werb, Z., & Bergers, G. (2005) · Nature Cell Biology · doi:10.1038/ncb1288 · Cited by 551
Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche.
Díaz‐Flores, L., Gutiérrez, R., Madrid, J. F., Varela, H., Valladares, F., Acosta, E., Martı́n-Vasallo, P., & Díaz-Flores, L. (2009) · PubMed · doi:10.14670/hh-24.909 · Cited by 547
Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease
Hamilton, N. B. (2010) · Frontiers in Neuroenergetics · doi:10.3389/fnene.2010.00005 · Cited by 513
Pericytes and vascular stability
VONTELL, D., Armulik, A., & Betsholtz, C. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2005.10.019 · Cited by 503
Chondrogenic and Adipogenic Potential of Microvascular Pericytes
Farrington, C., Crofts, N. J., Doherty, M. J., Ashton, B. A., Griffin-Jones, C., & Canfield, A. E. (2004) · Circulation · doi:10.1161/01.cir.0000144457.55518.e5 · Cited by 470
The Significance of Vascular and Neural Apoptosis to the Pathology of Diabetic Retinopathy
Barber, A. J., Gardner, T. W., & Abcouwer, S. F. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6293 · Cited by 446
Insight into the physiological functions of PDGF through genetic studies in mice
Betsholtz, C. (2004) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2004.03.005 · Cited by 437
CNS Microvascular Pericytes Exhibit Multipotential Stem Cell Activity
Dore-Duffy, P., Katychev, A., Wang, X., & Van Buren, E. (2006) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600272 · Cited by 414
Endothelium‐specific platelet‐derived growth factor‐B ablation mimics diabetic retinopathy
Enge, M., Bjarnegård, M., Gerhardt, H., Gustafsson, E., Kalén, M., Asker, N., Hammes, H., Shani, M., Fässler, R., & Betsholtz, C. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf418 · Cited by 409
Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain
Fernández-Klett, F., Offenhauser, N., Dirnagl, U., Priller, J., & Lindauer, U. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011321108 · Cited by 399
Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
Rajantie, I., Ilmonen, M., Alminaite, A., Özerdem, U., Alitalo, K. K., & Salvén, P. (2004) · Blood · doi:10.1182/blood-2004-01-0336 · Cited by 390
Heterogeneity of microvascular pericytes for smooth muscle type alpha-actin.
Nehls, V., & Drenckhahn, D. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.113.1.147 · Cited by 388
Pericyte involvement in capillary sprouting during angiogenesis in situ
Nehls, V., Denzer, K., & Drenckhahn, D. (1992) · Cell and Tissue Research · doi:10.1007/bf00645048 · Cited by 376
Der Feinere Bau der Blutcapillaren
Zimmermann, K. W. (1923) · Springer eBooks · doi:10.1007/978-3-642-92456-9 · Cited by 374
Fate Maps of Neural Crest and Mesoderm in the Mammalian Eye
Gage, P. J., Rhoades, W. R., Prucka, S. K., & Hjalt, T. Å. H. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.05-0691 · Cited by 374
Role of the Blood–Brain Barrier in Multiple Sclerosis
Ortiz, G. G., Pacheco-Moisés, F. P., Macías-Islas, M. Á., Flores-Alvarado, L. J., Mireles-Ramírez, M. A., González-Renovato, E. D., Hernández-Navarro, V. E., Sánchez-López, A. L., & Alatorre-Jiménez, M. A. (2014) · Archives of Medical Research · doi:10.1016/j.arcmed.2014.11.013 · Cited by 373
Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
Winkler, E. A., Sengillo, J. D., Sullivan, J. S., Henkel, J. S., Appel, S. H., & Zlokovic, B. V. (2013) · Acta Neuropathologica · doi:10.1007/s00401-012-1039-8 · Cited by 354
Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling
Winkler, E. A., Bell, R. D., & Zloković, B. V. (2010) · Molecular Neurodegeneration · doi:10.1186/1750-1326-5-32 · Cited by 354
Angiopoietin-2 Causes Pericyte Dropout in the Normal Retina
Hammes, H., Lin, J., Wagner, P., Feng, Y., Hagen, F. V., Krzizok, T. H., Renner, O., Breier, G., Brownlee, M., & Deutsch, U. (2004) · Diabetes · doi:10.2337/diabetes.53.4.1104 · Cited by 347
Diabetic Retinopathy: Targeting Vasoregression
Hammes, H., Feng, Y., Pfister, F., & Brownlee, M. (2010) · Diabetes · doi:10.2337/db10-0454 · Cited by 345
Transplantation of Human Pericyte Progenitor Cells Improves the Repair of Infarcted Heart Through Activation of an Angiogenic Program Involving Micro-RNA-132
Katare, R., Riu, F., Mitchell, K., Gubernator, M., Campagnolo, P., Cui, Y., Fortunato, O., Avolio, E., Cesselli, D., Beltrami, A. P., et al. (2011) · Circulation Research · doi:10.1161/circresaha.111.251546 · Cited by 344
Pericyte Loss in Diabetic Retinopathy: Mechanisms and Consequences
Beltramo, E., & Porta, M. (2013) · Current Medicinal Chemistry · doi:10.2174/09298673113209990022 · Cited by 331
Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells
Karow, M., Sánchez, R., Schichor, C., Masserdotti, G., Ortega, F., Heinrich, C., Gascón, S., Khan, M. A., Lie, D. C., Dellavalle, A., et al. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.07.007 · Cited by 316
Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner
Birbrair, A., Zhang, T., Files, D. C., Mannava, S., Smith, T. L., Wang, Z., Messi, M. L., Mintz, A., & Delbono, O. (2014) · Stem Cell Research & Therapy · doi:10.1186/scrt512 · Cited by 291
The Pericyte: A Forgotten Cell Type with Important Implications for A lzheimer's Disease?
Winkler, E. A., Sagare, A. P., & Zloković, B. V. (2014) · Brain Pathology · doi:10.1111/bpa.12152 · Cited by 284
Brain Vascular Pericytes Following Ischemia Have Multipotential Stem Cell Activity to Differentiate Into Neural and Vascular Lineage Cells
Nakagomi, T., Kubo, S., Nakano‐Doi, A., Sakuma, R., Lu, S., Narita, A., Kawahara, M., Taguchi, A., & Matsuyama, T. (2015) · Stem Cells · doi:10.1002/stem.1977 · Cited by 260
Contractile proteins in pericytes at the blood-brain and blood-retinal barriers
Bandopadhyay, R., Orte, C., Lawrenson, J. G., Reid, A. R., Silva, S. D., & Allt, G. (2001) · Journal of Neurocytology · doi:10.1023/a:1011965307612 · Cited by 255
Pericyte Migration
Pfister, F., Feng, Y., Hagen, F. V., Hoffmann, S., Molema, G., Hillebrands, J., Shani, M., Deutsch, U., & Hammes, H. (2008) · Diabetes · doi:10.2337/db08-0325 · Cited by 245
Human Pericytes for Ischemic Heart Repair
Chen, C.-W., Okada, M., Proto, J. D., Gao, X., Sekiya, N., Beckman, S., Corselli, M., Crisan, M., Saparov, A., Tobita, K., et al. (2012) · Stem Cells · doi:10.1002/stem.1285 · Cited by 241
Early Loss of Pericytes and Perivascular Stromal Cell-Induced Scar Formation after Stroke
Fernández‐Klett, F., Potas, J. R., Hilpert, D., Blazej, K., Radke, J., Huck, J. H. J., Engel, O., Stenzel, W., Genové, G., & Priller, J. (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2012.187 · Cited by 231
Morphology and Properties of Pericytes
Dore‐Duffy, P., & Cleary, K. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-938-3_2 · Cited by 222
Pathological features of cerebral cortical capillaries are doubled in Alzheimer's disease and Parkinson's disease
Farkas, E., de Jong, G. I., de Vos, R. A. I., Steur, E. N. H. J., & Luiten, P. G. M. (2000) · Acta Neuropathologica · doi:10.1007/s004010000195 · Cited by 222
Animal Models of Diabetic Retinopathy: Summary and Comparison
Lai, A. K. W., & Lo, A. (2013) · Journal of Diabetes Research · doi:10.1155/2013/106594 · Cited by 219
TNFα Is Required for Late BRB Breakdown in Diabetic Retinopathy, and Its Inhibition Prevents Leukostasis and Protects Vessels and Neurons from Apoptosis
Hu, H., Gandhi, J. K., Zhong, X., Wei, Y., Gong, J., Duh, E. J., & Vinores, S. A. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-5768 · Cited by 217
Neuroectodermal origin of brain pericytes and vascular smooth muscle cells
Korn, J., Christ, B., & Kurz, H. (2002) · Journal of Comparative Neurology · doi:10.1002/cne.1423 · Cited by 208
The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells
Paul, G., Özen, Í., Christophersen, N. S., Reinbothe, T. M., Bengzon, J., Visse, E., Jansson, K., Dannaeus, K., Henriques-Oliveira, C., Roybon, L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035577 · Cited by 206
Perivascular Multipotent Progenitor Cells in Human Organs
Crisan, M., Chen, C., Corselli, M., Andriolo, G., Lazzari, L., & Péault, B. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04967.x · Cited by 204
Skeletal muscle pericyte subtypes differ in their differentiation potential
Birbrair, A., Zhang, T., Wang, Z., Messi, M. L., Enikolopov, G., Mintz, A., & Delbono, O. (2012) · Stem Cell Research · doi:10.1016/j.scr.2012.09.003 · Cited by 204
Diabetes-Enhanced Tumor Necrosis Factor-α Production Promotes Apoptosis and the Loss of Retinal Microvascular Cells in Type 1 and Type 2 Models of Diabetic Retinopathy
Behl, Y., Krothapalli, P., Desta, T., DiPiazza, A., Roy, S., & Graves, D. T. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.071070 · Cited by 197
Regulation of Blood Flow in the Retinal Trilaminar Vascular Network
Kornfield, T. E., & Newman, E. A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1971-14.2014 · Cited by 195
Microarray analysis of blood microvessels from PDGF‐B and PDGF‐Rβ mutant mice identifies novel markers for brain pericytes
Bondjers, C., He, L., Takemoto, M., Norlin, J., Asker, N., Hellström, M., Lindahl, P., Betsholtz, C., Bondjers, C., He, L., et al. (2006) · The FASEB Journal · doi:10.1096/fj.05-4944fje · Cited by 193
Additive Effects of PDGF Receptor β Signaling Pathways in Vascular Smooth Muscle Cell Development
Tallquist, M. D., French, W. J., & Soriano, P. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000052 · Cited by 192
Contribution of Neural Crest-Derived Cells in the Embryonic and Adult Thymus
Foster, K., Sheridan, J. M., Veiga‐Fernandes, H., Roderick, K., Pachnis, V., Adams, R. H., Blackburn, C. C., Kioussis, D., & Coles, M. C. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.5.3183 · Cited by 179
Pericytes are involved in the pathogenesis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
Ghosh, M., Balbi, M., Hellal, F., Dichgans, M., Lindauer, U., & Plesnila, N. (2015) · Annals of Neurology · doi:10.1002/ana.24512 · Cited by 174
Rat Organic Anion Transporter 3 (rOAT3) Is Responsible for Brain-to-Blood Efflux of Homovanillic Acid at the Abluminal Membrane of Brain Capillary Endothelial Cells
Mori, S., Takanaga, H., Ohtsuki, S., Deguchi, T., Kang, Y., Hosoya, K., & Terasaki, T. (2003) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/01.wcb.0000050062.57184.75 · Cited by 172
Handbuch der Lehre von den Geweben des Menschen und der Thiere
Stricker, S. (1871) · Cited by 168
Pericytes as collagen-producing cells in excessive dermal scarring.
Sundberg, C., Ivarsson, M., Gerdin, B., & Rubin, K. (1996) · PubMed · Cited by 161
Angiopoietin 2 Induces Pericyte Apoptosis via α3β1 Integrin Signaling in Diabetic Retinopathy
Park, S. W., Yun, J.-H., Kim, J. H., Kim, K.-W., Cho, C., & Kim, J. H. (2014) · Diabetes · doi:10.2337/db13-1942 · Cited by 157
ATP: a vasoactive signal in the pericyte-containing microvasculature of the rat retina
Kawamura, H., Sugiyama, T., Wu, D. M., Kobayashi, M., Yamanishi, S., Katsumura, K., & Puro, D. G. (2003) · The Journal of Physiology · doi:10.1111/j.1469-7793.2003.00787.x · Cited by 156
Pericytes Derived from Adipose-Derived Stem Cells Protect against Retinal Vasculopathy
Mendel, T. A., Clabough, E. B. D., Kao, D. S., Demidova‐Rice, T. N., Durham, J. T., Zotter, B. C., Seaman, S. A., Cronk, S. M., Rakoczy, E. P., Katz, A. J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065691 · Cited by 154
Paucity of Pericytes in Germinal Matrix Vasculature of Premature Infants
Braun, A., Xu, H., Hu, F., Kocherlakota, P., Siegel, D. S., Chander, P. N., Ungvari, Z. I., Csiszár, A., Nedergaard, M., & Ballabh, P. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3281-07.2007 · Cited by 145
FOXO1 Plays an Important Role in Enhanced Microvascular Cell Apoptosis and Microvascular Cell Loss in Type 1 and Type 2 Diabetic Rats
Behl, Y., Krothapalli, P., Desta, T., Roy, S., & Graves, D. T. (2009) · Diabetes · doi:10.2337/db08-0537 · Cited by 138
The bone marrow constitutes a reservoir of pericyte progenitors
Lamagna, C., & Bergers, G. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.0506309 · Cited by 136
Neural Crest Origin of Perivascular Mesenchyme in the Adult Thymus
Müller, S. M., Stolt, C. C., Terszowski, G., Blum, C., Amagai, T., Kessaris, N., Iannarelli, P., Richardson, W. D., Wegner, M., & Rodewald, H.-R. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.8.5344 · Cited by 134
Combined Intramyocardial Delivery of Human Pericytes and Cardiac Stem Cells Additively Improves the Healing of Mouse Infarcted Hearts Through Stimulation of Vascular and Muscular Repair
Avolio, E., Meloni, M., Spencer, H. L., Riu, F., Katare, R., Mangialardi, G., Oikawa, A., Rodríguez-Arabaolaza, I., Dang, Z., Mitchell, K. J., et al. (2015) · Circulation Research · doi:10.1161/circresaha.115.306146 · Cited by 128
Pericyte coverage of retinal and cerebral capillaries.
Frank, R. N., Turczyn, T. J., & Das, A. (1990) · PubMed · Cited by 127
ATP: a vasoactive signal in the pericyte-containing microvasculature of the rat retina
Kawamura, H., Sugiyama, T., Wu, D. M., et al. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.047977 · Cited by 126
Expression of Three Recombinant Homodimeric Isoforms of PDGF inSaccharomyces cerevisiae: Evidence for Difference in Receptor Binding and Functional Activities
Östman, A., Bäckström, G., Fong, N. M., Betsholtz, C., Wernstedt, C., Hellman, U., Westermark, B., Valenzuela, P., & Heldin, C. (1989) · Growth Factors · doi:10.3109/08977198908998003 · Cited by 123
The 140‐kDa Protein of Blood‐Brain Barrier‐Associated Pericytes Is Identical to Aminopeptidase N
Kunz, J., Krause, D., Kremer, M., & Dermietzel, R. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62062375.x · Cited by 118
Potential interactions between pericytes and oligodendrocyte precursor cells in perivascular regions of cerebral white matter
Maki, T., Maeda, M., Uemura, M. T., Lo, E. K., Terasaki, Y., Liang, A. C., Shindo, A., Choi, Y. K., Taguchi, A., Matsuyama, T., et al. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.04.047 · Cited by 113
Diffuse and persistent blood–spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow mesenchymal stem cells
Matsushita, T., Lankford, K. L., Arroyo, E. J., Sasaki, M., Neyazi, M., Radtke, C., & Kocsis, J. D. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.03.001 · Cited by 112
In SituObservation of Living Pericytes in Rat Retinal Capillaries
Schönfelder, U., Hofer, A., Paul, M., & Funk, R. H. W. (1998) · Microvascular Research · doi:10.1006/mvre.1998.2086 · Cited by 110
A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes
Wisniewska‐Kruk, J., Hoeben, K. A., Vogels, I. M. C., Gaillard, P. J., Noorden, C. J. F. V., Schlingemann, R. O., & Klaassen, I. (2011) · Experimental Eye Research · doi:10.1016/j.exer.2011.12.003 · Cited by 108
Vascular Reactivity of Optic Nerve Head and Retinal Blood Vessels in Glaucoma - A Review
Venkataraman, S. T., Flanagan, J. G., & Hudson, C. D. (2010) · Microcirculation · doi:10.1111/j.1549-8719.2010.00045.x · Cited by 106
Morphology and Topography of Retinal Pericytes in the Living Mouse Retina Using In Vivo Adaptive Optics Imaging and Ex Vivo Characterization
Schallek, J. B., Geng, Y., Nguyen, H., & Williams, D. R. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-12581 · Cited by 103
Cholinergic regulation of pericyte-containing retinal microvessels
Wu, D. M., Kawamura, H., Sakagami, K., Kobayashi, M., & Puro, D. G. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01007.2002 · Cited by 100
Protection of Retinal Ganglion Cells and Retinal Vasculature by Lycium Barbarum Polysaccharides in a Mouse Model of Acute Ocular Hypertension
Mi, X.-S., Qian, F., Lo, A., Chang, R. C., Lin, B., Chung, S. K., & So, K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045469 · Cited by 95
Sox10‐iCreERT2: A mouse line to inducibly trace the neural crest and oligodendrocyte lineage
Simon, C., Lickert, H., Götz, M., & Dimou, L. (2011) · genesis · doi:10.1002/dvg.22003 · Cited by 92
Recruitment of pericytes and astrocytes is closely related to the formation of tight junction in developing retinal vessels
Kim, J. H., Kim, J. H., Yu, Y. S., Kim, D. H., & Kim, K. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21884 · Cited by 92
Does the Blood-brain Barrier Play a Role in Glaucoma?
Grieshaber, M. C., & Flammer, J. (2007) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2007.08.005 · Cited by 91
Retina-specific expression of PDGF-B versus PDGF-A: vascular versus nonvascular proliferative retinopathy.
Mori, K., Gehlbach, P. L., Ando, A., Dyer, G., Lipinsky, E., Chaudhry, A., Hackett, S. F., & Campochiaro, P. A. (2002) · PubMed · Cited by 88
Pericytes as a new target for pathological processes in CADASIL
Dziewulska, D., & Lewandowska, E. (2012) · Neuropathology · doi:10.1111/j.1440-1789.2011.01290.x · Cited by 86
Photoreceptor-Specific Expression of Platelet-Derived Growth Factor-B Results in Traction Retinal Detachment
Seo, M. S., Okamoto, N., Vinores, M. A., Vinores, S. A., Hackett, S. F., Yamada, H., Yamada, E., Derevjanik, N. L., LaRochelle, W. J., Zack, D. J., et al. (2000) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64612-3 · Cited by 85
Neural Crest Origin of Retinal and Choroidal Pericytes
Trost, A., Schroedl, F., Lange, S., Rivera, F. J., Tempfer, H., Korntner, S. H., Stolt, C. C., Wegner, M., Bogner, B., Kaser-Eichberger, A., et al. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-12946 · Cited by 85
Self-citation
Contribution of Bone Marrow–Derived Pericyte Precursor Cells to Corneal Vasculogenesis
Özerdem, U., Alitalo, K. K., Salvén, P., & Li, A. I. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.05-0309 · Cited by 80
Association of thrombospondin-1 with osteogenic differentiation of retinal pericytes in vitro
Canfield, A. E., Sutton, A. B., Hoyland, J. A., & Schor, A. M. (1996) · Journal of Cell Science · doi:10.1242/jcs.109.2.343 · Cited by 78
Molecular analysis of blood–retinal barrier loss in the Akimba mouse, a model of advanced diabetic retinopathy
Wisniewska‐Kruk, J., Klaassen, I., Vogels, I. M. C., Magno, A. L., Lai, C., Noorden, C. J. F. V., Schlingemann, R. O., & Rakoczy, E. P. (2014) · Experimental Eye Research · doi:10.1016/j.exer.2014.03.005 · Cited by 75
Abnormal pericyte recruitment as a cause for pulmonary hypertension in Adams–Oliver syndrome
Patel, M. S., Taylor, G. P., Bharya, S., Al-Sannaa, N. A., Adatia, I., Chitayat, D. A., Lewis, M. E. S., & Human, D. G. (2004) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.30221 · Cited by 72
Roles of Inner Blood-Retinal Barrier Organic Anion Transporter 3 in the Vitreous/Retina-to-Blood Efflux Transport of p-Aminohippuric Acid, Benzylpenicillin, and 6-Mercaptopurine
Hosoya, K., Makihara, A., Tsujikawa, Y., Yoneyama, D., Mori, S., Terasaki, T., Akanuma, S., Tomi, M., & Tachikawa, M. (2008) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.146381 · Cited by 67
Acetylcholinesterase Inhibition Promotes Retinal Vasoprotection and Increases Ocular Blood Flow in Experimental Glaucoma
Almasieh, M., MacIntyre, J. N., Pouliot, M., Casanova, C., Vaucher, E., Kelly, M. E. M., & Polo, A. D. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-11481 · Cited by 65
Migration of Oligodendrocyte Progenitor Cells Is Controlled by Transforming Growth Factor β Family Proteins during Corticogenesis
Choe, Y., Huynh, T., & Pleasure, S. J. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1156-14.2014 · Cited by 61
Pericyte form and distribution in rat retinal and uveal capillaries.
Tilton, R. G., Miller, E. J., Kilo, C., & Williamson, J. R. (1985) · PubMed · Cited by 58
Amyloid‐β‐induced Degeneration of Human Brain Pericytes Is Dependent on the Apolipoprotein E Genotype
Verbeek, M. M., Nostrand, W. E. V., Otte‐Höller, I., Wesseling, P., & de Waal, R. M. W. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06368.x · Cited by 57
Retinal Findings in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)
Robinson, W. P., Galetta, S. L., McCluskey, L. F., Forman, M. S., & Balcer, L. J. (2001) · Survey of Ophthalmology · doi:10.1016/s0039-6257(00)00206-x · Cited by 52
Brain pericyte plasticity as a potential drug target in CNS repair
Lange, S., Trost, A., Tempfer, H., Bauer, H., Bauer, H., Rohde, E., Reitsamer, H. A., Franklin, R. J. M., Aigner, L., & Rivera, F. J. (2012) · Drug Discovery Today · doi:10.1016/j.drudis.2012.12.007 · Cited by 50
Self-citation
Ophthalmologic Findings in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
Roine, S., Harju, M. P., Kivelä, T., Pöyhönen, M., Nikoskelainen, E. K., Tuisku, S., Kalimo, H., Viitanen, M. H., & Summanen, P. A. (2006) · Ophthalmology · doi:10.1016/j.ophtha.2006.03.030 · Cited by 49
Immunolocalization of platelet‐derived growth factor receptor‐β ( PDGFR‐β ) and pericytes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ( CADASIL )
Craggs, L., Fenwick, R., Oakley, A. E., Ihara, M., & Kalaria, R. N. (2014) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12188 · Cited by 49
Perivascular mesenchymal stem cells in the adult human brain: a future target for neuroregeneration?
Özen, Í., Boix, J., & Paul, G. (2012) · Clinical and Translational Medicine · doi:10.1186/2001-1326-1-30 · Cited by 49
Pericytes in the eye
Pfister, F., Przybyt, E., Harmsen, M. C., & Hammes, H. (2013) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1272-6 · Cited by 48
Time-dependent retinal ganglion cell loss, microglial activation and blood-retina-barrier tightness in an acute model of ocular hypertension
Trost, A., Motloch, K. A., Bruckner, D., Schroedl, F., Bogner, B., Kaser-Eichberger, A., Runge, C., Strohmaier, C., Klein, B., Aigner, L., et al. (2015) · Experimental Eye Research · doi:10.1016/j.exer.2015.05.010 · Cited by 45
Self-citation
Ultrastructural Changes in Cerebral Capillary Pericytes in Aged Notch3 Mutant Transgenic Mice
Gu, X., Liu, X., Fagan, A., Gonzalez-Toledo, M. E., & Zhao, L. (2012) · Ultrastructural Pathology · doi:10.3109/01913123.2011.620220 · Cited by 43
Neurovascular Interaction and the Pathophysiology of Diabetic Retinopathy
Qian, H., & Ripps, H. (2011) · Experimental Diabetes Research · doi:10.1155/2011/693426 · Cited by 42
Photoreceptor degeneration, structural remodeling and glial activation: A morphological study on a genetic mouse model for pericyte deficiency
Genové, G., Mollick, T., & Johansson, K. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.09.013 · Cited by 40
Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2
André, P., Saubaméa, B., Cochois, V., Cynthia Marie-claire, A., Cattelotte, J., Smirnova, M., Schinkel, A. H., Scherrmann, J., & Cisternino, S. (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2012.109 · Cited by 38
Histopathological abnormalities in ocular blood vessels of CADASIL patients
Haritoglou, C., Hoops, J. P., Stefani, F. H., Mehraein, P., Kampik, A., & Dichgans, M. (2004) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2004.02.073 · Cited by 38
Fluorescein leakage of the optic disc in glaucomatous optic neuropathy
Arend, O., Remky, A., Plange, N., Kaup, M., & Schwartz, B. (2005) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-004-1092-7 · Cited by 38
Nucleoside diphosphate kinase B deficiency causes a diabetes-like vascular pathology via up-regulation of endothelial angiopoietin-2 in the retina
Qiu, Y. H., Zhao, D., Butenschön, V.-M., Bauer, A. T., Schneider, S. W., Skolnik, E. Y., Hammes, H., Wieland, T., & Feng, Y. (2015) · Acta Diabetologica · doi:10.1007/s00592-015-0752-x · Cited by 32
Changes in the expression pattern of blood-brain barrier-associated pericytic aminopeptidase N (pAP N) in the course of acute experimental autoimmune encephalomyelitis
Kunz, J., Krause, D., Gehrmann, J., & Dermietzel, R. (1995) · Journal of Neuroimmunology · doi:10.1016/0165-5728(95)00024-v · Cited by 30
Contractility of retinal pericytes grown on silicone elastomer substrates is through a protein kinase A-mediated intracellular pathway in response to vasoactive peptides
Markhotina, N., Liu, G. J., & Martin, D. K. (2007) · IET Nanobiotechnology · doi:10.1049/iet-nbt:20060019 · Cited by 29
Expression of sonic hedgehog downstream genes is modified in rat embryos exposed in utero to a distal inhibitor of cholesterol biosynthesis
Gofflot, F., Gaoua, W., Bourguignon, L., Roux, C., & Picard, J. J. (2001) · Developmental Dynamics · doi:10.1002/1097-0177(2000)9999:9999 · Cited by 27
Inhibition of amyloid-β-induced cell death in human brain pericytes in vitro
Rensink, A. A. M., Verbeek, M. M., Otte‐Höller, I., ten Donkelaar, H. J., de Waal, R. M. W., & Kremer, B. P. H. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03218-3 · Cited by 27
Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF‐B in myelinating tracts
Forsberg‐Nilsson, K., Erlandsson, A., Zhang, X., Ueda, H., Svensson, K., Nistér, M., Trapp, B. D., Peterson, A. C., & Westermark, B. (2003) · Glia · doi:10.1002/glia.10191 · Cited by 22
A CNS-Specific Hypomorphic Pdgfr -Beta Mutant Model of Diabetic Retinopathy
Jadeja, S., Mort, R. L., Keighren, M., Hart, A. W., Joynson, R., Wells, S. E., Potter, P. K., & Jackson, I. J. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-11125 · Cited by 19
Photoreceptor-specific overexpression of platelet-derived growth factor induces proliferation of endothelial cells, pericytes, and glial cells and aberrant vascular development: an ultrastructural and immunocytochemical study
Vinores, S. A., Seo, M. S., Derevjanik, N. L., & Campochiaro, P. A. (2003) · Developmental Brain Research · doi:10.1016/s0165-3806(02)00581-3 · Cited by 19
Platelet-Derived Growth Factor Over-Expression in Retinal Progenitors Results in Abnormal Retinal Vessel Formation
Edqvist, P.-H. D., Niklasson, M., Vidal‐Sanz, M., Hallböök, F., & Forsberg‐Nilsson, K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042488 · Cited by 17
Vascular changes in the posterior eye segment of secondary angle-closure glaucoma: cause or consequence?
May, C. A., & Mittag, T. W. (2006) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-006-0307-5 · Cited by 8

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Research works printed but not linked: 2

Rouget, 1879, Sur la contractilite des capillaries sanguins, CR Acad. Sci., 88, 916
Tidhar, 2001, A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells, Dev. Dyn., 220, 60, 10.1002/1097-0177(2000)9999:9999::aid-dvdy10893.3.co;2-o · DOI

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Molecular diversity and specializations among the cells of the adult mouse brain
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“Mural cells are intrinsic to the endothelium and control vascular development, stability, and homeostasis (Sweeney et al., 2016; Trost et al., 2016).”
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Nation, D. A., Sweeney, M. D., Montagne, A., Sagare, A. P., D’Orazio, L. M., Pachicano, M., Sepehrband, F., Nelson, A. R., Buennagel, D. P., Harrington, M. G., et al. (2019) · Nature Medicine · doi:10.1038/s41591-018-0297-y · Cited by 1,728
Mechanisms of macular edema: Beyond the surface
Daruich, A., Matet, A., Moulin, A., Kowalczuk, L., Nicolas, M., Sellam, A., Rothschild, P.-R., Omri, S., Gélizé, E., Jonet, L., et al. (2017) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2017.10.006 · Cited by 744
Neurodegeneration in diabetic retinopathy: does it really matter?
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Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer’s disease
Koronyo, Y., Biggs, D., Barrón, E., Boyer, D. S., Pearlman, J. A., Au, W. J., Kile, S. J., Blanco, A., Fuchs, D.-T. S., Ashfaq, A., et al. (2017) · JCI Insight · doi:10.1172/jci.insight.93621 · Cited by 521

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Authors: Trost, A., Lange, S., Schroedl, F., Bruckner, D., Motloch, K. A., Bogner, B., Kaser-Eichberger, A., Strohmaier, C., Runge, C., Aigner, L., Rivera, F. J., & Reitsamer, H. A.
Affiliations: Paracelsus Medical University (AT)
Corresponding author: Reitsamer, Herbert A.
ORCID: Trost, Andrea
Lange, Simona
Schroedl, Falk
Motloch, Karolina A.
Kaser-Eichberger, Alexandra
Strohmaier, Clemens
Aigner, Ludwig
Rivera, Francisco J.
Reitsamer, Herbert A.
Venue: Frontiers in Cellular Neuroscience
Publisher: Frontiers Media SA
Published: 2016-02-04
Volume: 10
Pages: 20-20
ISSN: 1662-5102 (ISSN-L)
DOI: 10.3389/fncel.2016.00020
PMC: PMC4740376
OpenAlex: W2312261107
Cited by: 244
References: 141
Citations by year: 2026: 9 · 2025: 23 · 2024: 20 · 2023: 23 · 2022: 25 · 2021: 27 · 2020: 24 · 2019: 33 · 2018: 26 · 2017: 26 · 2016: 8
FWCI: 2.72
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
Locations: Frontiers in Cellular Neuroscience (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Glaucoma Research Foundation
Topics: Life Sciences › Neuroscience › Neurology › Barrier Structure and Function Studies
Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
Keywords: pericytes, retinal pericytes, brain pericytes, neurovascular unit, blood-retinal barrier, blood-brain barrier, angiogenesis, pericyte loss, diabetic retinopathy, pericyte heterogeneity, multipotent differentiation, regenerative therapy

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Brain and Retinal Pericytes: Origin, Function and Role

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