Transcriptome analysis on maternal separation rats with depression-related manifestations ameliorated by electroacupuncture

The use of the elevated plus maze as an assay of anxiety-related behavior in rodents

Walf, A. A., & Frye, C. A. (2007) · Nature Protocols · doi:10.1038/nprot.2007.44 · Cited by 3,035 · see citing works

Fast and effective prediction of microRNA/target duplexes

REHMSMEIER, M., STEFFEN, P., HÖCHSMANN, M., & GIEGERICH, R. (2004) · RNA · doi:10.1261/rna.5248604 · Cited by 2,560 · see citing works

The mouse light/dark box test

Bourin, M., & Hascoët, M. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01274-3 · Cited by 1,440 · see citing works

EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments

Leng, N., Dawson, J. A., Thomson, J. A., Ruotti, V., Rissman, A. I., Smits, B. M. G., Haag, J. D., Gould, M. N., Stewart, R. M., & Kendziorski, C. M. (2013) · Bioinformatics · doi:10.1093/bioinformatics/btt087 · Cited by 1,304 · see citing works

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

Tye, K. M., Mirzabekov, J. J., Warden, M. R., Ferenczi, E. A., Tsai, H.-C., Finkelstein, J., Kim, S.-Y., Adhikari, A., Thompson, K. R., Andalman, A. S., et al. (2013) · Nature · doi:10.1038/nature11740 · Cited by 1,073 · see citing works

Sucrose preference test for measurement of stress-induced anhedonia in mice

Liu, M.-Y., Yin, C.-Y., Zhu, L.-J., Zhu, X.-H., Xu, C., Luo, C.-X., Chen, H., Zhu, D.-Y., & Zhou, Q.-G. (2018) · Nature Protocols · doi:10.1038/s41596-018-0011-z · Cited by 1,026 · see citing works

Sparse whole-genome sequencing identifies two loci for major depressive disorder

CONVERGE consortium, Cai, N., Bigdeli, T. B., Kretzschmar, W., Li, Y., Liang, J., Song, L., Hu, J., Li, Q., Jin, W., et al. (2015) · Nature · doi:10.1038/nature14659 · Cited by 864 · see citing works

Early life experience alters response of adult neurogenesis to stress

Mirescu, C., Peters, J. D., & Gould, E. (2004) · Nature Neuroscience · doi:10.1038/nn1290 · Cited by 625 · see citing works

Astrocyte-derived ATP modulates depressive-like behaviors

Cao, X., Li, L.-P., Wang, Q., Wu, Q., Hu, H.-H., Zhang, M., Fang, Y.-Y., Zhang, J., Li, S.-J., Xiong, W.-C., et al. (2013) · Nature Medicine · doi:10.1038/nm.3162 · Cited by 615 · see citing works

Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

Li, J. Z., Bunney, B. G., Meng, F., Hagenauer, M. H., Walsh, D. M., Vawter, M. P., Evans, S. J., Choudary, P. V., Cartagena, P., Barchas, J. D., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305814110 · Cited by 589 · see citing works

Cluster analysis of gene expression dynamics

Ramoni, M. F., Sebastiani, P., & Kohane, I. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.132656399 · Cited by 466 · see citing works

Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

Bond, A. M., VanGompel, M. J. W., Sametsky, E. A., Clark, M. F., Savage, J. C., Disterhoft, J. F., & Kohtz, J. D. (2009) · Nature Neuroscience · doi:10.1038/nn.2371 · Cited by 399 · see citing works

Childhood emotional, physical, and sexual abuse, and diagnoses of depressive and anxiety disorders in adult psychiatric outpatients

Gibb, B. E., Chelminski, I., & Zimmerman, M. A. (2006) · Depression and Anxiety · doi:10.1002/da.20238 · Cited by 389 · see citing works

The incidence and course of depression in bereaved youth 21 months after the loss of a parent to suicide, accident, or sudden natural death

Brent, D., Melhem, N., Donohoe, M. B., & Walker, M. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08081244 · Cited by 382 · see citing works

Acupuncture for depression

Smith, C. A., Hay, P. P., & MacPherson, H. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004046.pub3 · Cited by 340 · see citing works

Early-life stress, HPA axis adaptation, and mechanisms contributing to later health outcomes

Maniam, J., Antoniadis, C., & Morris, M. J. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00073 · Cited by 295 · see citing works

Rat genetics: attachign physiology and pharmacology to the genome

Jacob, H. J., & Kwitek, A. E. (2002) · Nature Reviews Genetics · doi:10.1038/nrg702 · Cited by 274 · see citing works

Early maternal separation: a rodent model of depression and a prevailing human condition

Vetulani, J. (2013) · Pharmacological Reports · doi:10.1016/s1734-1140(13)71505-6 · Cited by 255 · see citing works

Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs

Dale, E., Bang‐Andersen, B., & Sánchez, C. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.03.011 · Cited by 238 · see citing works

Cellular and molecular basis for stress-induced depression

Seo, J.-S., Wei, J., Qin, L., Kim, Y., Yan, Z., & Greengard, P. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.118 · Cited by 235 · see citing works

Structural variations in prefrontal cortex mediate the relationship between early childhood stress and spatial working memory

Hanson, J. L., Chung, M. K., Avants, B. B., Rudolph, K. D., Shirtcliff, E. A., Gee, J. C., Davidson, R. J., & Pollak, S. D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0307-12.2012 · Cited by 219 · see citing works

Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment

Alboni, S., van Dijk, R. M., Poggini, S., Milior, G., Perrotta, M., Drenth, T., Brunello, N., Wolfer, D. P., Limatola, C., Amrein, I., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2015.142 · Cited by 207 · see citing works

Healthcare Costs Associated with Depression in Medically Ill Fee‐for‐Service Medicare Participants

Unützer, J., Schoenbaum, M., Katon, W. J., Fan, M., Pincus, H. A., Hogan, D., & Taylor, J. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.02134.x · Cited by 197 · see citing works

Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder

Bunney, B. G., Li, J. Z., Walsh, D. M. A., Stein, R., Vawter, M. P., Cartagena, P. M., Barchas, J. D., Schatzberg, A. F., Myers, R., Watson, S. J., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.138 · Cited by 185 · see citing works

hsa_circRNA_103636: potential novel diagnostic and therapeutic biomarker in Major depressive disorder

Cui, X., Niu, W., Kong, L., He, M., Jiang, K., Chen, S., Zhong, A., Li, W., Lu, J., & Zhang, L. (2016) · Biomarkers in Medicine · doi:10.2217/bmm-2016-0130 · Cited by 150 · see citing works

Molecular biomarkers of depression

Gururajan, A., Clarke, G. A., Dinan, T. G., & Cryan, J. F. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.02.011 · Cited by 134 · see citing works

Microarray Profiling and Co-Expression Network Analysis of Circulating lncRNAs and mRNAs Associated with Major Depressive Disorder

Liu, Z., Li, X., Sun, N., Xu, Y. J., Meng, Y.-Q., Yang, C., Wang, Y., & Zhang, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093388 · Cited by 121 · see citing works

Maternal separation and maternal care act independently on the development of HPA responses in male rats

Macrı̀, S., Chiarotti, F., & Würbel, H. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.03.031 · Cited by 109 · see citing works

Early‐life stress induces anxiety‐like behaviors and activity imbalances in the medial prefrontal cortex and amygdala in adult rats

Ishikawa, J., Nishimura, R., & Ishikawa, A. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.12825 · Cited by 107 · see citing works

Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing

Hansen, K. F., Sakamoto, K., Pelz, C., Impey, S., & Obrietan, K. H. (2014) · Scientific Reports · doi:10.1038/srep06930 · Cited by 103 · see citing works

Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms

Tchenio, A., Lecca, S., Valentinova, K., & Mameli, M. (2017) · Nature Communications · doi:10.1038/s41467-017-01192-1 · Cited by 103 · see citing works

The link between long noncoding RNAs and depression

Huang, X., Luo, Y., Mao, Y.-S., & Jian-lin, J. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.06.004 · Cited by 92 · see citing works

Increased responsiveness of presumed 5-HT cells to citalopram in adult rats subjected to prolonged maternal separation relative to brief separation

Arborelius, L., Hawks, B. W., Owens, M. J., Plotsky, P. M., & Nemeroff, C. B. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1883-x · Cited by 89 · see citing works

Orexin prevents depressive-like behavior by promoting stress resilience

Ji, M., Zhang, X., Chen, Z., Wang, J.-J., & Zhu, J. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0127-0 · Cited by 87 · see citing works

Adolescent voluntary exercise attenuated hippocampal innate immunity responses and depressive-like behaviors following maternal separation stress in male rats

Sadeghi, M., Peeri, M., & Hosseini, M.-J. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.05.017 · Cited by 83 · see citing works

Activity-dependent BDNF release via endocytic pathways is regulated by synaptotagmin-6 and complexin

Wong, Y., Lee, C.-M. J., 谢文俊, Cui, B., & Poo, M.-M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1511830112 · Cited by 82 · see citing works

Post-weaning isolation promotes food intake and body weight gain in rats that experienced neonatal maternal separation

Ryu, V., Yoo, S. B., Kang, D. W., Lee, J.-H., & Jahng, J. W. (2009) · Brain Research · doi:10.1016/j.brainres.2009.08.006 · Cited by 78 · see citing works

Acupuncture Promotes Angiogenesis after Myocardial Ischemia through H3K9 Acetylation Regulation at VEGF Gene

Fu, S., He, S.-Y., Xu, B., Hu, C., Lu, S.-F., Shen, W., Huang, Y., Hong, H., Li, Q., Wang, N., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094604 · Cited by 75 · see citing works

MicroRNA-encoded behavior in Drosophila

Picão-Osório, J., Johnston, J., Landgraf, M., Berni, J., & Alonso, C. R. (2015) · Science · doi:10.1126/science.aad0217 · Cited by 73 · see citing works

Altered Expression Pattern of Clock Genes in a Rat Model of Depression

Christiansen, S. L., Bouzinova, E., Fahrenkrug, J., & Wiborg, O. (2016) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyw061 · Cited by 73 · see citing works

Mother-newborn separation at birth in hospitals: A possible risk for neurodevelopmental disorders?

Császár-Nagy, N., & Bókkon, I. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.08.013 · Cited by 73 · see citing works

iTRAQ-based quantitative analysis of hippocampal postsynaptic density-associated proteins in a rat chronic mild stress model of depression

Han, X., Shao, W., Liu, Z., Fan, S., Yu, J. H., Chen, J., Qiao, R., Zhou, J., & Xie, P. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.04.006 · Cited by 71 · see citing works

Early life stress accelerates age-induced effects on neurogenesis, depression, and metabolic risk

Ruiz, R., Roque, A., Pineda, E., Licona-Limón, P., Valdez-Alarcón, J. J., & Lajud, N. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.07.012 · Cited by 70 · see citing works

Potential antiinflammatory effects of acupuncture in a chronic stress model of depression in rats

Lü, J., Shao, R.-H., Hu, L., Tu, Y., & Guo, J. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.02.040 · Cited by 65 · see citing works

Behavioral effects in adolescence and early adulthood in two length models of maternal separation in male rats

Banqueri, M., Méndez, M., & Arias, J. L. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.02.006 · Cited by 62 · see citing works

Methyl donor supplementation in rats reverses the deleterious effect of maternal separation on depression-like behaviour

Paternain, L., Martišová, E., Campión, J., Martínez, J. A., Ramírez, M. J., & Milagro, F. I. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.11.031 · Cited by 60 · see citing works

Voluntary Exercise During Adolescence Mitigated Negative the Effects of Maternal Separation Stress on the Depressive-Like Behaviors of Adult Male Rats: Role of NMDA Receptors

Masrour, F. F., Peeri, M., Azarbayjani, M. A., & Hosseini, M. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2519-6 · Cited by 58 · see citing works

Adolescence fluoxetine increases serotonergic activity in the raphe-hippocampus axis and improves depression-like behaviors in female rats that experienced neonatal maternal separation

Yoo, S. B., Kim, B. T., Kim, J. Y., Ryu, V., Kang, D. W., Lee, J.-H., & Jahng, J. W. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.08.013 · Cited by 53 · see citing works

Mechanisms Underlying the Antidepressant Response of Acupuncture via PKA/CREB Signaling Pathway

Jiang, H., Zhang, X., Wang, Y., Zhang, H., Li, J., Yang, X., Zhao, B., Zhang, C., Yu, M., Xu, M., et al. (2017) · Neural Plasticity · doi:10.1155/2017/4135164 · Cited by 51 · see citing works

Hypothalamic-pituitary-adrenal axis activity and cognition in major depression: The role of remission status

Salvat-Pujol, N., Labad, J., Urretavizcaya, M., de Arriba-Arnau, A., Segalàs, C., Real, E., Ferrer, A., Crespo, J. M., Jiménez-Murcia, S., Soriano-Mas, C., et al. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.11.007 · Cited by 47 · see citing works

Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis

van der Doelen, R. H. A., Deschamps, W., D'Annibale, C., Peeters, D. G. A., Wevers, R. A., Zelena, D., Homberg, J. R., & Kozicz, T. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.57 · Cited by 46 · see citing works

Acupuncture ameliorates inflammatory response in a chronic unpredictable stress rat model of depression

Lü, J., Shao, R.-H., Jin, S.-Y., Hu, L., Tu, Y., & Guo, J. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.11.010 · Cited by 46 · see citing works

Evidence Map of Acupuncture

Hempel, S., Taylor, S. L., Solloway, M. R., Miake-Lye, I. M., Beroes, J. M., Shanman, R., Booth, M. J., Siroka, A. M., & Shekelle, P. (2014) · Europe PMC (PubMed Central) · Cited by 45 · see citing works

Increased adrenocorticotropic hormone (ACTH) levels predict severity of depression after six months of follow-up in outpatients with major depressive disorder

Choi, K. W., Na, E. J., D, M. F. M., Mischoulon, D., Cho, H., & Jeon, H. J. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.09.047 · Cited by 44 · see citing works

Chronic mild stress-induced alterations of clock gene expression in rat prefrontal cortex: modulatory effects of prolonged lurasidone treatment

Calabrese, F., Savino, E., Papp, M., Molteni, R., & Riva, M. A. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.12.023 · Cited by 43 · see citing works

Hippocampal gene expression in a rat model of depression after electroacupuncture at the Baihui and Yintang acupoints

Duan, D., Yang, X., Tu, Y., & Chen, L. (2014) · Neural Regeneration Research · doi:10.4103/1673-5374.125333 · Cited by 39 · see citing works

Total saponins from the leaves of <i>Panax notoginseng</i>  inhibit depression on mouse chronic unpredictable mild stress model by regulating circRNA expression

Zhang, H., Chen, Z., Zhong, Z., Gong, W., & Li, J. (2018) · Brain and Behavior · doi:10.1002/brb3.1127 · Cited by 37 · see citing works

Functional Roles of Complexin in Neurotransmitter Release at Ribbon Synapses of Mouse Retinal Bipolar Neurons

Vaithianathan, T., Henry, D. L., Akmentin, W., & Matthews, G. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2703-14.2015 · Cited by 36 · see citing works

Perceived life stress exposure modulates reward-related medial prefrontal cortex responses to acute stress in depression

Kumar, P., Slavich, G. M., Berghorst, L. H., Treadway, M. T., Brooks, N. H., Dutra, S. J., Greve, D. N., O’Donovan, A., Bleil, M. E., Maninger, N., et al. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.03.035 · Cited by 36 · see citing works

Genome-wide transcriptome analysis of hippocampus in rats indicated that TLR/NLR signaling pathway was involved in the pathogenisis of depressive disorder induced by chronic restraint stress

Wang, Y., Jiang, H., Meng, H., Lü, J., Li, J., Zhang, X., Yang, X., Zhao, B., Sun, Y., & Bao, T. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.07.021 · Cited by 36 · see citing works

Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses

Mortensen, L. S., Park, S. J. H., Ke, J.-B., Cooper, B. H., Zhang, L., Imig, C., Löwel, S., Reim, K., Brose, N., Demb, J. B., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.012 · Cited by 35 · see citing works

Melancholy, anhedonia, apathy: the search for separable behaviors and neural circuits in depression

Post, R. J., & Warden, M. R. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.02.018 · Cited by 35 · see citing works

Efficacy Evaluation for Depression with Somatic Symptoms Treated by Electroacupuncture Combined with Fluoxetine

Duan, D., Tu, Y., Chen, L., & Zheng-jun, W. U. (2009) · 中医杂志：英文版 · doi:10.1016/s0254-6272(09)60057-1 · Cited by 33 · see citing works

A microarray study of chronic unpredictable mild stress rat blood serum with electro-acupuncture intervention

Duan, D. M., Dong, X., Tu, Y., & Liu, P. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.05.054 · Cited by 28 · see citing works

Influence of citicoline on citalopram-induced antidepressant activity in depressive-like symptoms in male mice

Azizi, M. R., Torkaman‐Boutorabi, A., Akhondzadeh, S., Nejatisafa, A., Sadat‐Shirazi, M., & Zarrindast, M. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.08.002 · Cited by 28 · see citing works

MicroRNA Profiling Response to Acupuncture Therapy in Spontaneously Hypertensive Rats

Wang, J.-Y., Li, H., Ma, C., Wang, J., Lai, X., & Zhou, S. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/204367 · Cited by 27 · see citing works

Effect of soothing-liver and nourishing-heart acupuncture on early selective serotonin reuptake inhibitor treatment onset for depressive disorder and related indicators of neuroimmunology: a randomized controlled clinical trial

Liu, Y., Hui, F., Mo, Y., Jingfang, G., Hongjing, M., Mingfen, S., Shengdong, W., Yan, Y., & Wenjuan, L. (2015) · 中医杂志：英文版 · doi:10.1016/s0254-6272(15)30132-1 · Cited by 27 · see citing works

Effects of acupuncture on vascular dementia (VD) animal models: a systematic review and meta-analysis

Zhang, Z., Liu, Z., Deng, H., & Chen, Q. (2018) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-018-2345-z · Cited by 27 · see citing works

Estradiol accelerates the effects of fluoxetine on serotonin 1A receptor signaling

Li, Q., Sullivan, N. R., McAllister, C. E., de Kar, L. D. V., & Muma, N. A. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.11.005 · Cited by 26 · see citing works

Effect of acupuncture stimulation on rats with depression induced by water-immersion stress

Tanahashi, N., Takagi, K., Amagasu, N., Wang, G., Mizuno, K., Kawanoguchi, J., Guo, Y., & Ishida, T. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.02.051 · Cited by 26 · see citing works

Acupuncture for behavioral changes of experimental depressive disorder: a systematic review and meta-analysis

Kou, R., Chen, H., Yu, M., Xu, T., Fu, S.-P., & Lu, S.-F. (2017) · Scientific Reports · doi:10.1038/s41598-017-09712-1 · Cited by 22 · see citing works

Influence of environmental enrichment on the volume of brain regions sensitive to early life stress by maternal separation in rats

González‐Pardo, H., Arias, J. L., Vallejo, G., & Conejo, N. M. (2019) · Psicothema · doi:10.7334/psicothema2018.290 · Cited by 20 · see citing works

Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders

Coplan, J. D., Fulton, S. L., Reiner, W. J., Jackowski, A. P., Panthangi, V., Perera, T. D., Gorman, J. M., Huang, Y., Tang, C. Y., Hof, P. R., et al. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00440 · Cited by 17 · see citing works

Electroacupuncture Ameliorates Cognitive Deficit and Improves Hippocampal Synaptic Plasticity in Adult Rat with Neonatal Maternal Separation

Guo, L., Liang, X., Liang, Z., Liu, X., Jiang, H., Zheng, Y., Yao, L., & Chen, Y. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/2468105 · Cited by 14 · see citing works

Differential anxiety-related behaviours and brain activation in Tph2-deficient female mice exposed to adverse early environment

Auth, C. S., Weidner, M. T., Popp, S., Strekalova, T. V., Schmitt-Böhrer, A. G., van den Hove, D., Lesch, K., & Waider, J. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.07.103 · Cited by 13 · see citing works

[Effects of electroacupuncture on circadian rhythm of temperature and melatonin in depression rats model induced by chronic stress].

Yao, H., Song, H., Mo, Y., Zhang, T., Han, X.-B., & Li, Z. (2014) · PubMed · Cited by 12 · see citing works

Effects of Electroacupuncture on the Daily Rhythmicity of Intestinal Movement and Circadian Rhythmicity of Colonic Per2 Expression in Rats with Spinal Cord Injury

Cheng, J., Wang, X., Guo, J., Yang, Y., Zhang, W., Xie, B., Zhu, Z., Lu, Y., & Zhu, Y. (2016) · BioMed Research International · doi:10.1155/2016/9860281 · Cited by 7 · see citing works

Childhood Emotional Abuse Moderates Associations Among Corticomotor White Matter Structure and Stress Neuromodulators in Women With and Without Depression

Frost, C. P., Meyerand, M. E., Birn, R. M., Hoks, R. M., Walsh, E. C., & Abercrombie, H. C. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00256 · Cited by 7 · see citing works

[Study on electroacupuncture treatment of depression by magnetic resonance imaging].

Duan, D., Tu, Y., Chen, L., & Wu, Z.-J. (2009) · PubMed · Cited by 6 · see citing works

Research Into Media Exposure Behaviors of Left-Behind Children in Rural Areas From the Perspective of Media as Substitutes

Minghong, W. (2015) · Higher education of social science · doi:10.3968/6886 · Cited by 4 · see citing works

Effect of soothing-liver and nourishing-heart acupuncture on early selective serotonin reuptake inhibitor treatment onset for depressive disorder and related indicators of neuroimmunology：a randomized controlled clinical trial

Liu, ̆, Y., Feng, Hui, H., Mö, Yali, Gao, G., Jingfang, Mao, M., Hongjing, et al. (2015) · 中医杂志：英文版 · Cited by 4 · see citing works

Effect of Electroacupuncture on Insomnia in Patients With Depression

Yin, X., Li, W., Liang, T., Lu, B., Yue, H., Li, S., Zhong, V. W., Zhang, W., Li, X., Zhou, S. Y., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.20563 · Cited by 161 · see citing works

Early-Life Stress Induces Depression-Like Behavior and Synaptic-Plasticity Changes in a Maternal Separation Rat Model: Gender Difference and Metabolomics Study

Cui, Y., Cao, K., Lin, H., Cui, S., Shen, C., Wen, W., Mo, H., Dong, Z., Bai, S., Yang, L., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00102 · Cited by 119 · see citing works

Unraveling the epigenetic landscape of depression: focus on early life stress

Torres‐Berrío, A., Issler, O., Parise, E. M., & Nestler, E. J. (2019) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2019.21.4/enestler · Cited by 102 · see citing works

The mechanism of electroacupuncture for depression on basic research: a systematic review

Han, X., Gao, Y., Yin, X., Zhang, Z., Lao, L., Chen, Q., & Xu, S. (2021) · Chinese Medicine · doi:10.1186/s13020-020-00421-y · Cited by 87 · see citing works

Effects of acupuncture on hypothalamic–pituitary–adrenal axis: Current status and future perspectives

Zheng, J., Zhu, J., Wang, Y., & Tian, Z. (2024) · Journal of Chinese Integrative Medicine · doi:10.1016/j.joim.2024.06.004 · Cited by 56 · see citing works

The Effect of Early Maternal Separation Combined With Adolescent Chronic Unpredictable Mild Stress on Behavior and Synaptic Plasticity in Adult Female Rats

Huang, J., Shen, C., Ye, R., Shi, Y., & Li, W. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.539299 · Cited by 40 · see citing works

Circular RNAs in depression: Biogenesis, function, expression, and therapeutic potential

Gan, H., Lei, Y., Yuan, N., Tang, K., Hao, W., Ma, Q., Wu, M., Zhou, X., Li, X., Huang, J., et al. (2021) · Biomedicine &amp; Pharmacotherapy · doi:10.1016/j.biopha.2021.111244 · Cited by 41 · see citing works

Acupuncture treatment for post-stroke depression: Intestinal microbiota and its role

Jiang, H., Deng, S., Zhang, J., Chen, J., Li, B., Zhu, W., Zhang, M., Zhang, C., & Meng, Z. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1146946 · Cited by 40 · see citing works

Mechanisms of acupuncture in treating depression: a review

Ma, J., Yin, X., Cui, K., Wang, J., Li, W., & Xu, S. (2025) · Chinese Medicine · doi:10.1186/s13020-025-01080-7 · Cited by 34 · see citing works

Influence of early life stress on depression: from the perspective of neuroendocrine to the participation of gut microbiota

Tan, X., Zhang, L., Wang, D., Guan, S., Lu, P., Xu, X., & Xu, H. (2021) · Aging · doi:10.18632/aging.203746 · Cited by 33 · see citing works

Early Life Stress Induces Different Behaviors in Adolescence and Adulthood May Related With Abnormal Medial Prefrontal Cortex Excitation/Inhibition Balance

Chen, Y., Zheng, Y., Yan, J., Zhu, C., Zeng, X., Zheng, S., Li, W., Yao, L., Xia, Y., Su, W.-W., et al. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.720286 · Cited by 32 · see citing works

Acupuncture may play a key role in anti-depression through various mechanisms in depression

Li, P., Zhao, J., Wei, X., Luo, L., Chu, Y., Zhang, T., Zhu, A., & Yan, J. (2024) · Chinese Medicine · doi:10.1186/s13020-024-00990-2 · Cited by 32 · see citing works

Electro-acupuncture inhibits HDAC2 via modulating gut microbiota to ameliorate SNI-induced pain and depression-like behavior in rats

Li, S., Huang, J., Luo, D., Fu, W., & Liu, J. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.02.069 · Cited by 30 · see citing works

Enduring effects of early-life adversity on reward processes: A systematic review and meta-analysis of animal studies

Duque-Quintero, M., Hooijmans, C. R., Hurowitz, A., Ahmed, A., Barris, B., Homberg, J. R., Hen, R., Harris, A. Z., Balsam, P. D., & Atsak, P. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104849 · Cited by 24 · see citing works

Electroacupuncture Ameliorates Neuroinflammation-Mediated Cognitive Deficits through Inhibition of NLRP3 in Presenilin1/2 Conditional Double Knockout Mice

Li, K., Shi, G., Zhao, Y., Chen, Y., Gao, J., Yao, L., Zhao, J., Li, H., Xu, Y., & Chen, Y. (2021) · Neural Plasticity · doi:10.1155/2021/8814616 · Cited by 22 · see citing works

Maternal separation in mice leads to anxiety-like/aggressive behavior and increases immunoreactivity for glutamic acid decarboxylase and parvalbumin in the adolescence ventral hippocampus

Kim, E.-G., Chang, W., Shin, S., Adhikari, A. S., Seol, G. H., Song, D., & Min, S. S. (2022) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2023.27.1.113 · Cited by 21 · see citing works

Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus

Chen, Y., Xie, S.-Y., Chen, C., & Lu, D. (2021) · Molecular Brain · doi:10.1186/s13041-021-00860-0 · Cited by 19 · see citing works

Effect of Electroacupuncture on Neurological Deficit and Activity of Clock and Bmal1 in Cerebral Ischemic Rats

Xu, X., Fang, Q., Huang, W. M., Li, B., Zhou, X., Zhou, Z., & Li, J. (2020) · Current Medical Science · doi:10.1007/s11596-020-2295-9 · Cited by 17 · see citing works

Metabolomics Analysis on Mice With Depression Ameliorated by Acupoint Catgut Embedding

Duan, L., Qiu, W., Bai, G., Qiao, Y., Su, S., Lo, P.-C., Lu, Y., Xu, G., Wang, Q., Li, M., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.703516 · Cited by 17 · see citing works

Gut microbiota as a novel target for treating anxiety and depression: from mechanisms to multimodal interventions

Ruohan, Z., Ruting, W., Hongxi, W., Zhenjin, H., Jiale, L., Rongxin, Z., Jiang, F., & Yuanbo, S. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1664800 · Cited by 18 · see citing works

Electroacupuncture-modulated extracellular ATP levels in prefrontal cortex ameliorated depressive-like behavior of maternal separation rats

Zheng, Y., Pan, L., Jiang, H., Yan, J., Xia, Y., Lin, C., Chen, X., Zhao, Q., Zeng, Q., Julikezi, M., et al. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114548 · Cited by 16 · see citing works

Electroacupuncture alleviates perioperative hypothalamus-pituitary-adrenal axis dysfunction via circRNA-miRNA-mRNA networks

Wang, Y., Hu, W., Han, J., Zheng, J., Jiang, N., Feng, Y., & Tian, Z. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1115569 · Cited by 15 · see citing works

Lactobacillus reuteri effects on maternal separation stress in newborn mice

Park, E. S., Freeborn, J., Venna, V. R., Roos, S., Rhoads, J. M., & Liu, Y. (2021) · Pediatric Research · doi:10.1038/s41390-021-01374-0 · Cited by 15 · see citing works

Electroacupuncture alleviates spatial memory deficits in METH withdrawal mice by enhancing astrocyte‐mediated glutamate clearance in the dCA1

He, T., Li, N., Shi, P., Xu, X., Nie, J., Lu, X., Yu, P., Fan, Y., Ge, F., & Guan, X. (2021) · Addiction Biology · doi:10.1111/adb.13068 · Cited by 14 · see citing works

Involvement of purinergic P2Y1R in antidepressant-like effects of electroacupuncture treatment on social isolation stress mice

Yu, L., Wang, Y., Zhang, H., Li, M., Chen, G., Hao, J., & Xie, M. (2022) · Purinergic Signalling · doi:10.1007/s11302-021-09827-1 · Cited by 13 · see citing works

Differential anxiety-related behaviours and brain activation in Tph2-deficient female mice exposed to adverse early environment

Auth, C. S., Weidner, M. T., Popp, S., Strekalova, T. V., Schmitt-Böhrer, A. G., van den Hove, D., Lesch, K., & Waider, J. (2018) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.07.103 · Cited by 13 · see citing works

The emerging role of long noncoding RNA in depression and its implications in diagnostics and therapeutic responses

Zhong, X.-L., Du, Y., Chen, L. T., & Cheng, Y. (2023) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2023.06.017 · Cited by 12 · see citing works

Circular RNAs: New players involved in the regulation of cognition and cognitive diseases

Yu, X., Liu, H., Chang, N., Fu, W., Guo, Z., & Wang, Y. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1097878 · Cited by 11 · see citing works

m6A Regulator-Mediated RNA Methylation Modification Patterns are Involved in the Pathogenesis and Immune Microenvironment of Depression

Wang, Y., Wang, X., Yang, C., Hua, W., & Wang, H. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.865695 · Cited by 9 · see citing works

The Impact of Electroacupuncture Early Intervention on the Brain Lipidome in a Mouse Model of Post-traumatic Stress Disorder

Zhou, C., Xue, F., Shi, Q., Xue, S., Zhang, T., Ma, X., Yu, L., Liu, C., Wang, H., & Peng, Z. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.812479 · Cited by 9 · see citing works

Contribution of Growth Arrest-Specific 5/miR-674 to the Hypothalamus Pituitary Adrenal Axis Regulation Effect by Electroacupuncture following Trauma

Zhu, J., Guo, C., Lu, P., Shao, S.-J., & Tu, B. (2021) · NeuroImmunoModulation · doi:10.1159/000513385 · Cited by 9 · see citing works

Identification of differentially expressed genes in the medial prefrontal cortex of rats subjected to chronic unpredictable mild stress and treated with electroacupuncture

Zhang, Y., Zhang, H., Zheng, X., Hou, Y. M., Chang, X., Zhang, L., Wang, Y., & Chen, S. (2024) · Genomics · doi:10.1016/j.ygeno.2024.110901 · Cited by 8 · see citing works

Electroacupuncture as adjunctive therapy for insomnia via targeting the GABAergic microbiota-gut-brain axis: a mini review

Wang, X., Yan, L., Zhang, X., Liu, X., & Yang, B. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1613408 · Cited by 9 · see citing works

Effect of Electroacupuncture and Counseling on Sub-Threshold Depression: A Study Protocol for a Multicenter Randomized Controlled Trial

Wang, X., Lin, H., Jiang, X., Ma, M.-N., Shi, D., Fan, C., Yin, S., Wu, S., Yu, L., Li, D., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00346 · Cited by 8 · see citing works

Efficacy and mechanism of acupuncture in animal models of depressive-like behaviors: a systematic review and meta-analysis

Huang, Y., Chen, W., Li, X., Tan, T., Wang, T., Qiu, S., Li, G., Yang, C., Li, M., & Duan, L. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1330594 · Cited by 7 · see citing works

A Meta‐Analysis of the Effects of Early Life Stress on the Prefrontal Cortex Transcriptome Reveals Long‐Term Downregulation of Myelin‐Related Gene Expression

Duan, T. Q., Hagenauer, M. H., Flandreau, E. I., Bader, A., Nguyen, D. M., Maras, P. M., de Lima, R. M. S., Gyles, T. M., Mclain, C., Meaney, M. J., et al. (2025) · Brain and Behavior · doi:10.1002/brb3.70608 · Cited by 6 · see citing works

Hypothalamic Gene Expression in a Rat Model of Chronic Unpredictable Mild Stress Treated with Electroacupuncture

Wang, Y., Chang, X., Zhang, H., Hou, Y. M., Zheng, X., Zhang, Y., & Chen, S. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04124-w · Cited by 6 · see citing works

Epigenetic Landscape Changes Due to Acupuncture Treatment: From Clinical to Basic Research

Hong, H., Jing, X., Liu, S.-B., Peng, Y., & Zhu, B. (2020) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-020-2852-x · Cited by 6 · see citing works

Dysfunctional circular RNA network in major depressive disorder: dissecting the cell identity and potential clinical applications

Tan, L., Zhao, W., Wang, H. Y., Huang, X., Lin, Y., Yin, L., Liu, X., Wang, J., Wu, N., & Wang, H. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03167-x · Cited by 8 · see citing works

Hypothesis paper: electroacupuncture targeting the gut–brain axis to modulate neurocognitive determinants of eating behavior—toward a proof of concept in the obese minipig model

Zhang, X., Chen, H., & Val‐Laillet, D. (2020) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-020-00864-0 · Cited by 5 · see citing works

Transcriptome analysis of rats with chronic unpredictable mild stress treated with electroacupuncture

Chang, X.-L., Wang, Y., Hou, Y., Cheng, W., & Chen, S.-Z. (2024) · Brain and Behavior · doi:10.1002/brb3.70045 · Cited by 3 · see citing works

Bridging tradition and innovation: Acupuncture for depression through clinical efficacy and neurobiological insights

Xu, N., Xu, S., & Wang, L. (2025) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2025.103307 · Cited by 2 · see citing works

Antidepressant mechanism of traditional Chinese medicine: Involving regulation of circadian clock genes

Lv, S., Huang, Y., Ma, Y., & Teng, J. (2024) · Medicine · doi:10.1097/md.0000000000036266 · Cited by 2 · see citing works

Electroacupuncture restores maternal separation-induced glutamatergic presynaptic deficits of the medial prefrontal cortex in adulthood

Zheng, X., Zheng, Y., Zhai, Z., Chen, Y., Zhu, Y., Qiu, G., Wang, B., Wang, S., Chen, Y., & Yan, J. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.02.049 · Cited by 2 · see citing works

Efficacy and safety of electroacupuncture on treating mild to moderate first-episode depression: a study protocol for a randomized controlled trial

Xia, J., Jiang, M., Yin, X., Wang, Z., Li, F., Wei, H., Jin, C., Hu, Y., Chen, J., & Xu, S. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1521859 · Cited by 2 · see citing works

A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelinPreprint

Duan, T. Q., Hagenauer, M. H., Flandreau, E. I., Bader, A., Nguyen, D. M., Maras, P. M., de Lima, R. M. S., Gyles, T. M., Mclain, C., Meaney, M. J., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.22.624315 · Cited by 2 · see citing works

Research Advances in Multimodal Framework-Based Identification and Therapeutic Management of Post-Stroke Depression via the Microbiota-Gut-Brain Axis

Shen, M., Yu, P., Xiong, Q., Sun, Z., Zhang, Y., & Yang, M. (2025) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s564175 · Cited by 1 · see citing works

Acupuncture for treating depression in adults: systematic review and metanalysis / Acupuntura no tratamento da depressão em adultos: revisão sistemática e metanálise

Paiva, M. A. B., Chaves, G. L., Oliveira, D. D. S., Isidoro, G. M., Carvalho, M. L. N., Costa, I. C. P., Chaves, É. D. C. L., & Moura, C. D. C. (2022) · Brazilian Journal of Health Review · doi:10.34119/bjhrv5n2-324 · Cited by 1 · see citing works

Electro-acupuncture Alleviates METH Withdrawal-induced Spatial Memory Deficits by Restoring Astrocyte-drived Glutamate Uptake in dCA1Preprint

Shi, P., Li, Z., Xu, X., Nie, J., Liu, D., Cai, Q., Zhao, Y., Guan, Y., Ge, F., & Guan, X. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.20.106153

Beneficial effect of electroacupuncture on the distribution of foreign substances in the brain of rats developing depression-like behavior

He, J., Rubini, P., Li, B.-M., Yin, H., Tang, Y., & Illés, P. (2023) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2023.03.014

Advances in the clinical efficacy and mechanisms of acupressure for depression treatment: A comprehensive review

Zhuang, Y., Tsang, H. W. H., & Jessie Jingxia, L. I. N. (2026) · Brain Behavior and Immunity Integrative · doi:10.1016/j.bbii.2026.100153

Electroacupuncture alleviates depressive symptoms in post-stroke depression rat models by AMPK-mediated mitochondrial pathway

He, J., Yang, D., Ye, Y., & Zhu, X. (2026) · Psychopharmacology · doi:10.1007/s00213-025-06955-z

Transcriptome analysis of rats with chronic unpredictable mild stress treated with electroacupuncture

Chang, X.-L., Wang, Y., Hou, Y., Cheng, W., & Chen, S.-Z. (2024) · Brain and Behavior · doi:10.1002/brb3.70045 · Cited by 3 · see citing works

Identification of differentially expressed genes in the medial prefrontal cortex of rats subjected to chronic unpredictable mild stress and treated with electroacupuncture

Zhang, Y., Zhang, H., Zheng, X., Hou, Y. M., Chang, X., Zhang, L., Wang, Y., & Chen, S. (2024) · Genomics · doi:10.1016/j.ygeno.2024.110901 · Cited by 8 · see citing works

Electroacupuncture-modulated extracellular ATP levels in prefrontal cortex ameliorated depressive-like behavior of maternal separation rats

Zheng, Y., Pan, L., Jiang, H., Yan, J., Xia, Y., Lin, C., Chen, X., Zhao, Q., Zeng, Q., Julikezi, M., et al. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114548 · Cited by 16 · see citing works

Gene Chips-aided Analysis on the Profiles of Hippocampal Whole-genome Expression in Depression Rats Following Electroacupuncture Treatment

Jiang, L., & Ling-ling1, W. (2010) · DOAJ (DOAJ: Directory of Open Access Journals)

Hypothalamic Gene Expression in a Rat Model of Chronic Unpredictable Mild Stress Treated with Electroacupuncture

Wang, Y., Chang, X., Zhang, H., Hou, Y. M., Zheng, X., Zhang, Y., & Chen, S. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04124-w · Cited by 6 · see citing works