The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Ketogenic Diet for Obesity: Friend or Foe?
Open accessAbstract
Obesity is reaching epidemic proportions and is a strong risk factor for a number of cardiovascular and metabolic disorders such as hypertension, type 2 diabetes, dyslipidemia, atherosclerosis, and also certain types of cancers. Despite the constant recommendations of health care organizations regarding the importance of weight control, this goal often fails. Genetic predisposition in combination with inactive lifestyles and high caloric intake leads to excessive weight gain. Even though there may be agreement about the concept that lifestyle changes affecting dietary habits and physical activity are essential to promote weight loss and weight control, the ideal amount and type of exercise and also the ideal diet are still under debate. For many years, nutritional intervention studies have been focused on reducing dietary fat with little positive results over the long-term. One of the most studied strategies in the recent years for weight loss is the ketogenic diet. Many studies have shown that this kind of nutritional approach has a solid physiological and biochemical basis and is able to induce effective weight loss along with improvement in several cardiovascular risk parameters. This review discusses the physiological basis of ketogenic diets and the rationale for their use in obesity, discussing the strengths and the weaknesses of these diets together with cautions that should be used in obese patients.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Potential Decline in Life Expectancy in the United States in the 21st Century
Olshansky, S. J., Passaro, D. J., Hershow, R. C., Layden, J., Carnes, B. A., Brody, J., Hayflick, L., Butler, R. N., Allison, D. B., & Ludwig, D. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmsr043743 · Cited by 2,612
Nordmann, A. J., Nordmann, A., Briel, M., Keller, U., Yancy, W. S., Brehm, B. J., & Bucher, H. C. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.3.285 · Cited by 973 · cited 1×
“As a matter of fact there are still no definitive data on what dietary protocols are most effective in both the short and long term [6], or even what is the correct nutritional approach in general [7].”
BackgroundDiets with high or low protein content and glycemic index for weight-loss maintenance
Larsen, T. M., Dalskov, S.-M., van Baak, M., Jebb, S. A., Papadaki, A., Pfeiffer, A. F. H., Martinez, J. A., Handjieva-Darlenska, T., Kunešová, M., Pihlsgård, M., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1007137 · Cited by 843
Brehm, B. J., Seeley, R. J., Daniels, S. R., & D’Alessio, D. A. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021480 · Cited by 830
Bueno, N. B., de Melo, I. S. V., de Oliveira, S. L., & da Rocha Ataide, T. (2013) · British Journal of Nutrition · doi:10.1017/s0007114513000548 · Cited by 778 · cited 4×
“While there are many studies which demonstrate that a ketogenic diet, at least in the short-term, results in greater weight loss than low-fat diets [13], from a long term perspective the success of a nutritional approach is defined by the amount of weight regain [64].”
BackgroundInfluentialJohnstone, A. M., Horgan, G. W., Murison, S. D., Bremner, D. M., & Lobley, G. E. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.1.44 · Cited by 440 · cited 2×
“Other authors suggest a possible direct appetite suppressant action of the ketone bodies [42] and more in detail by the BHB that it is supposed to act both as a energy/satiety signal (according to Kennedy’s lipostatic theory) and as central satiety signal per se [26].”
BackgroundFreedman, M. R., King, J., & Kennedy, E. (2001) · Obesity Research · doi:10.1038/oby.2001.113 · Cited by 421
Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet
Volek, J. S., Phinney, S. D., Forsythe, C. E., Quann, E. E., Wood, R. J., Puglisi, M. J., Kraemer, W. J., Bibus, D. M., Fernandez, M. L., & Feinman, R. D. (2009) · Lipids · doi:10.1007/s11745-008-3274-2 · Cited by 397
Sandri, M., Barberi, L., Bijlsma, A. Y., Blaauw, B., Dyar, K. A., Milan, G., Mammucari, C., Meskers, C. G. M., Pallafacchina, G., Paoli, A., et al. (2013) · Biogerontology · doi:10.1007/s10522-013-9432-9 · Cited by 340
Self-citationThe defence of body weight: a physiological basis for weight regain after weight loss
Sumithran, P., & Proietto, J. (2013) · Clinical Science · doi:10.1042/cs20120223 · Cited by 310
Cited by
Kirkpatrick, C. F., Bolick, J. P., Kris-Etherton, P. M., Sikand, G., Aspry, K. E., Soffer, D. E., Willard, K.-E., & Maki, K. C. (2019) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2019.08.003 · Cited by 390
Role of ketogenic diets in neurodegenerative diseases (Alzheimer's disease and Parkinson's disease)
Włodarek, D. (2019) · Nutrients · doi:10.3390/nu11010169 · Cited by 301
International society of sports nutrition position stand: diets and body composition
Aragon, A. A., Schoenfeld, B. J., Wildman, R., Kleiner, S., VanDusseldorp, T., Taylor, L., Earnest, C. P., Arciero, P. J., Wilborn, C., Kalman, D. S., et al. (2017) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-017-0174-y · Cited by 301
Caprio, M., Infante, M., Moriconi, E., Armani, A., Fabbri, A., Mantovani, G., Mariani, S., Lubrano, C., Poggiogalle, E., Migliaccio, S., et al. (2019) · Journal of Endocrinological Investigation · doi:10.1007/s40618-019-01061-2 · Cited by 283
Effects of a Ketogenic Diet in Overweight Women with Polycystic Ovary Syndrome
Paoli, A., Mancin, L., Giacona, M. C., Bianco, A., & Caprio, M. (2020) · Journal of Translational Medicine · doi:10.1186/s12967-020-02277-0 · Cited by 281
Self-citationGomez-Arbelaez, D., Bellido, D., Castro, A. I., Ordoñez-Mayan, L., Carreira, J., Galban, C., Martinez-Olmos, M. A., Crujeiras, A. B., Sajoux, I., & Casanueva, F. F. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2385 · Cited by 214
Moreno, B., Crujeiras, A. B., Bellido, D., Sajoux, I., & Casanueva, F. F. (2016) · Endocrine · doi:10.1007/s12020-016-1050-2 · Cited by 204
Zhou, C., Wang, M., Liang, J., He, G., & Chen, N. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191610429 · Cited by 151
Mohorko, N., Černelič-Bizjak, M., Poklar-Vatovec, T., Grom, G., Kenig, S., Petelin, A., & Jenko-Pražnikar, Z. (2019) · Nutrition Research · doi:10.1016/j.nutres.2018.11.007 · Cited by 147
Napoleão, A., Fernandes, L., Miranda, C., & Marum, A. P. (2021) · Nutrients · doi:10.3390/nu13041302 · Cited by 103
Role of diet and exercise in aging, Alzheimer’s disease, and other chronic diseases
Khemka, S., Reddy, A., Garcia, R. I., Jacobs, M., Reddy, R. P., Roghani, A. K., Pattoor, V., Basu, T., Sehar, U., & Reddy, P. H. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102091 · Cited by 88
Paoli, A., Moro, T., Bosco, G., Bianco, A., Grimaldi, K., Camporesi, E., & Mangar, D. (2015) · Marine Drugs · doi:10.3390/md13020996 · Cited by 81
Self-citationThe Influence of Ketogenic Diet on Gut Microbiota: Potential Benefits, Risks and Indications
Santangelo, A., Corsello, A., Spolidoro, G. C. I., Trovato, C. M., Agostoni, C., Orsini, A., Milani, G. P., & Peroni, D. G. (2023) · Nutrients · doi:10.3390/nu15173680 · Cited by 80
Mei, S., Ding, J., Wang, K., Ni, Z., & Yu, J. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.876620 · Cited by 75
Ashtary-Larky, D., Bagheri, R., Asbaghi, O., Tinsley, G. M., Kooti, W., Abbasnezhad, A., Afrisham, R., & Wong, A. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1890689 · Cited by 50
Calcaterra, V., Magenes, V. C., Massini, G., De Sanctis, L., Fabiano, V., & Zuccotti, G. (2024) · Nutrients · doi:10.3390/nu16070938 · Cited by 35
Effect of Ketogenic Diet on Obesity and Other Metabolic Disorders: Narrative Review
Baylie, T., Ayelgn, T., Tiruneh, M., & Tesfa, K. (2024) · Diabetes, Metabolic Syndrome and Obesity · doi:10.2147/dmso.s447659 · Cited by 27
Metadata
- Authors
- Paoli, A.
- Venue
- International Journal of Environmental Research and Public Health
- Publisher
- MDPI AG
- Published
- 2014-02-19
- Volume
- 11
- Issue
- 2
- Pages
- 2092-2107
- ISSN
- 1660-4601 (ISSN-L)
- OpenAlex
- W1975693364
- Cited by
- 352
- References
- 15
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
