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Immobilized Enzymes in Biosensor Applications

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Nguyen, Hoang Hiep, Lee, Sun Hyeok, Lee, Ui Jin, Fermin, Cesar D., Kim, Moonil·2019·Materials
DOI 10.3390/ma12010121
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Abstract

Enzyme-based biosensing devices have been extensively developed over the last few decades, and have proven to be innovative techniques in the qualitative and quantitative analysis of a variety of target substrates over a wide range of applications. Distinct advantages that enzyme-based biosensors provide, such as high sensitivity and specificity, portability, cost-effectiveness, and the possibilities for miniaturization and point-of-care diagnostic testing make them more and more attractive for research focused on clinical analysis, food safety control, or disease monitoring purposes. Therefore, this review article investigates the operating principle of enzymatic biosensors utilizing electrochemical, optical, thermistor, and piezoelectric measurement techniques and their applications in the literature, as well as approaches in improving the use of enzymes for biosensors.

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  1. Gurung, 2013, A broader view: Microbial enzymes and their relevance in industries, medicine, and beyond, BioMed Res. Int., 2013, 329121, 10.1155/2013/329121 · DOI · Paper page
  2. 1993, Immobilized enzymes -learning from past successes and failures, Trends Biotechnol., 11, 471, 10.1016/0167-7799(93)90080-S · DOI · Paper page
  3. Nguyen, 2017, An overview of techniques in enzyme immobilization, Appl. Sci. Converg. Technol., 26, 157, 10.5757/ASCT.2017.26.6.157 · DOI · Paper page
  4. Sassolas, 2012, Immobilization strategies to develop enzymatic biosensors, Biotechnol. Adv., 30, 489, 10.1016/j.biotechadv.2011.09.003 · DOI · Paper page
  5. Mohamad, 2015, An overview of technologies for immobilization of enzymes and surface analysis techniques for immobilized enzymes, Biotechnol. Biotechnol. Equip., 29, 205, 10.1080/13102818.2015.1008192 · DOI · Paper page
  6. Barredo, J.L. (2005). Immobilization of enzymes by covalent attachment. Microbial Enzymes and Biotransformations, Springer. · DOI
  7. Rocchitta, G., Spanu, A., Babudieri, S., Latte, G., Madeddu, G., Galleri, G., Nuvoli, S., Bagella, P., Demartis, M.I., and Fiore, V. (2016). Enzyme biosensors for biomedical applications: Strategies for safeguarding analytical performances in biological fluids. Sensors, 16. · DOI · Paper page
  8. Guisan, J.M. (2013). Biomedical Applications of immobilized enzymes: An update. Methods in Molecular Biology, Springer. · doi:10.1007/978-1-62703-550-7
  9. Nigam, 2015, Enzyme based biosensors for detection of environmental pollutants-A review, J. Microbiol. Biotechnol., 25, 1773, 10.4014/jmb.1504.04010 · DOI
  10. Justino, C.I.L., Armando, C.D., and Rocha-Santos, T.A.P. (2017). Recent progress in biosensors for environmental monitoring: A review. Sensors, 17. · DOI · Paper page
  11. Amine, 2006, Enzyme inhibition-based biosensors for food safety and environmental monitoring, Biosens. Bioelectron., 21, 1405, 10.1016/j.bios.2005.07.012 · DOI
  12. Monosik, 2012, Application of enzyme biosensors in analysis of food and beverages, Food Anal. Methods, 5, 40, 10.1007/s12161-011-9222-4 · DOI
  13. Mehrotra, 2016, Biosensors and their applications—A review, J. Oral Biol. Craniofac. Res., 6, 153, 10.1016/j.jobcr.2015.12.002 · DOI · Paper page
  14. 2014, Malate quinone oxidoreductase biosensors based on tetrathiafulvalene and gold nanoparticles modified screen-printed carbon electrodes for malic acid determination in wine, Sens. Actuators B Chem., 202, 971, 10.1016/j.snb.2014.06.057 · doi:10.1016/j.snb.2014.06.057
  15. Clark, 1962, Electrode systems for continuous monitoring in cardiovascular surgery, Ann. N. Y. Acad. Sci., 102, 29, 10.1111/j.1749-6632.1962.tb13623.x · DOI · Paper page
  16. Bollella, 2018, Enzyme based amperometric biosensors, Curr. Opin. Electrochem., 10, 157, 10.1016/j.coelec.2018.06.003 · DOI · Paper page
  17. Kurbanoglu, 2018, Amperometric flow injection analysis of glucose and galactose based on engineered pyranose 2-oxidases and osmium polymers for biosensor applications, Electroanalysis, 30, 1496, 10.1002/elan.201800096 · doi:10.1002/elan.201800096
  18. Fernández, H., Arévalo, F.J., Granero, A.M., Robledo, S.N., Nieto, C.H.D., Riberi, W.I., and Zon, M.A. (2017). Electrochemical biosensors for the determination of toxic substances related to food safety developed in South America: Mycotoxins and herbicides. Chemosensors, 5. · doi:10.3390/chemosensors5030023
  19. Murugaiyan, 2014, Biosensors in clinical chemistry: An overview, Adv. Biomed. Res., 3, 67, 10.4103/2277-9175.125848 · DOI
  20. Tseng, 2009, Thermally stable improved first-generation glucose biosensors based on nafion/glucose-oxidase modified heated electrodes, Electrochem. Commun., 11, 1819, 10.1016/j.elecom.2009.07.030 · doi:10.1016/j.elecom.2009.07.030
  21. Treo, 2011, Real-time measurement of glucose using chrono-impedance technique on a second generation biosensor, Biosens. Bioelectron., 29, 200, 10.1016/j.bios.2011.08.018 · DOI
  22. Palmisano, 2002, A disposable, reagentless, third-generation glucose biosensor based on overoxidized poly(pyrrole)/tetrathiafulvalene-tetracyanoquinodimethane composite, Anal. Chem., 74, 5913, 10.1021/ac0258608 · DOI
  23. Tasca, 2013, Determination of lactose by a novel third generation biosensor based on a cellobiose dehydrogenase and aryl diazonium modified single wall carbon nanotubes electrode, Sens. Actuators B Chem., 177, 64, 10.1016/j.snb.2012.10.114 · doi:10.1016/j.snb.2012.10.114
  24. Das, 2016, Recent advances on developing 3rd generation enzyme electrode for biosensor applications, Biosens. Bioelectron., 79, 386, 10.1016/j.bios.2015.12.055 · DOI · Paper page
  25. Palanisamy, 2019, Enhanced reversible redox activity of hemin on cellulose microfiber integrated reduced graphene oxide for H2O2 biosensor applications, Carbohydr. Polym., 204, 152, 10.1016/j.carbpol.2018.10.001 · DOI
  26. Hassan, 2017, Tetracaine—selective electrodes with polymer membranes and their application in pharmaceutical formulation control, Arab. J. Chem., 10, S1484, 10.1016/j.arabjc.2013.04.029 · doi:10.1016/j.arabjc.2013.04.029
  27. Gupta, 2010, Drug selective poly(vinyl chloride)-based sensor of desipramine hydrochloride, Electrochim. Acta, 55, 1061, 10.1016/j.electacta.2009.09.061 · doi:10.1016/j.electacta.2009.09.061
  28. Dung, T.T., Oh, Y., Choi, S.J., Kim, I.D., Oh, M.K., and Kim, M. (2018). Applications and advances in bioelectronic noses for odour sensing. Sensors, 18. · DOI
  29. Lee, 2009, Ion-sensitive field-effect transistor for biological sensing, Sensors, 9, 7111, 10.3390/s90907111 · DOI · Paper page
  30. Caras, 1980, Field effect transistor sensitive to penicillin, Anal. Chem., 52, 1935, 10.1021/ac50062a035 · DOI · Paper page
  31. Yoon, 2008, Field-effect-transistor sensor based on enzyme-functionalized polypyrrole nanotubes for glucose detection, J. Phys. Chem. B, 112, 9992, 10.1021/jp800567h · DOI
  32. Luo, 2004, A novel glucose ENFET based on the special reactivity of MnO2 nanoparticles, Biosens. Bioelectron., 19, 1295, 10.1016/j.bios.2003.11.019 · DOI · Paper page
  33. Luo, 2004, Glucose biosensor based on ENFET doped with SiO2 nanoparticles, Sens. Actuators B Chem., 97, 249, 10.1016/j.snb.2003.08.024 · DOI
  34. Soldatkin, 2003, A novel urea sensitive biosensor with extended dynamic range based on recombinant urease and ISFETs, Biosens. Bioelectron., 19, 131, 10.1016/S0956-5663(03)00175-1 · DOI
  35. Rebriiev, 2004, Enzymatic biosensor based on the ISFET and photopolymeric membrane for the determination of urea, Electroanalysis, 16, 1891, 10.1002/elan.200403077 · doi:10.1002/elan.200403077
  36. Simonian, 2001, Enzyme-based biosensor for the direct detection of fluorine-containing organophosphates, Anal. Chim. Acta, 442, 15, 10.1016/S0003-2670(01)01131-X · DOI
  37. Simonian, 2004, FET-based biosensors for the direct detection of organophosphate neurotoxins, Electroanalysis, 16, 1896, 10.1002/elan.200403078 · DOI
  38. Dzyadevych, 2002, Development of enzyme biosensor based on pH-sensitive field-effect transistors for detection of phenolic compounds, Bioelectrochemistry, 55, 79, 10.1016/S1567-5394(01)00165-7 · doi:10.1016/s1567-5394(01)00165-7
  39. Soldatkin, 2005, Analysis of the potato glycoalkaloids by using of enzyme biosensor based on pH-ISFETs, Talanta, 66, 28, 10.1016/j.talanta.2004.11.006 · doi:10.1016/j.talanta.2004.11.006
  40. Sant, 2004, Development of a creatinine-sensitive sensor for medical analysis, Sens. Actuators B Chem., 103, 260, 10.1016/j.snb.2004.04.104 · DOI
  41. Fung, 1986, A generalized theory of an electrolyte-insulator-semiconductor field-effect transistor, IEEE Trans. Electron Devices, 33, 8, 10.1109/T-ED.1986.22429 · DOI · Paper page
  42. Seki, 1998, Biosensors based on light-addressable potentiometric sensors for urea, penicillin and glucose, Anal. Chim. Acta, 373, 9, 10.1016/S0003-2670(98)00364-X · DOI
  43. Rogers, 1991, Light addressable potentiometric biosensor for the detection of anticholinesterases, Anal. Lett., 24, 191, 10.1080/00032719108052896 · doi:10.1080/00032719108052896
  44. Fernando, 1993, Rapid detection of anticholinesterase insecticides by a reusable light addressable potentiometric biosensor, J. Agric. Food Chem., 41, 511, 10.1021/jf00027a031 · doi:10.1021/jf00027a031
  45. Wu, 2009, A novel biomimetic olfactory-based biosensor for single olfactory sensory neuron monitoring, Biosens. Bioelectron., 24, 1498, 10.1016/j.bios.2008.07.065 · doi:10.1016/j.bios.2008.07.065
  46. Yu, 2009, A novel design of multifunctional integrated cell-based biosensors for simultaneously detecting cell acidification and extracellular potential, Biosens. Bioelectron., 24, 1462, 10.1016/j.bios.2008.08.045 · doi:10.1016/j.bios.2008.08.045
  47. Wu, 2016, Sensing of double-stranded DNA molecules by their intrinsic molecular charge using the light-addressable potentiometric sensor, Sens. Actuators B Chem., 229, 506, 10.1016/j.snb.2016.02.004 · doi:10.1016/j.snb.2016.02.004
  48. Du, 2018, Dual functional extracellular recording using a light-addressable potentiometric sensor for bitter signal transduction, Anal. Chim. Acta, 1022, 106, 10.1016/j.aca.2018.03.012 · doi:10.1016/j.aca.2018.03.012
  49. Soldatkin, 1994, Glucose sensitive conductometric biosensor with additional Nafion membrane: reduction of influence of buffer capacity on the sensor response and extension of its dynamic range, Anal. Chim. Acta, 288, 197, 10.1016/0003-2670(93)E0627-J · doi:10.1016/0003-2670(93)e0627-j
  50. Lee, 2000, Sol–gel-derived thick-film conductometric biosensor for urea determination in serum, Anal. Chim. Acta, 404, 195, 10.1016/S0003-2670(99)00699-6 · doi:10.1016/s0003-2670(99)00699-6
  51. Mikkelsen, 1989, Conductometric transducers for enzyme-based biosensors, Anal. Chem., 61, 1737, 10.1021/ac00190a029 · doi:10.1021/ac00190a029
  52. Bilitewski, 1992, Thick film biosensors for urea, Sens. Actuators B Chem., 7, 321, 10.1016/0925-4005(92)80317-Q · doi:10.1016/0925-4005(92)80317-q
  53. Soldatkin, 1994, Thin-film conductometric biosensors for glucose and urea determination, Biosens. Bioelectron., 9, 217, 10.1016/0956-5663(94)80124-X · doi:10.1016/0956-5663(94)80124-x
  54. Kirdeciler, 2011, A novel urea conductometric biosensor based on zeolite immobilized urease, Talanta, 85, 1435, 10.1016/j.talanta.2011.06.034 · doi:10.1016/j.talanta.2011.06.034
  55. Ho, 1999, Electrochemical sensor for measurement of urea and creatinine in serum based on ac impedance measurement of enzyme-catalyzed polymer transformation, Anal. Chem., 71, 1940, 10.1021/ac981367d · doi:10.1021/ac981367d
  56. Cullen, 1990, Multi-analyte miniature conductance biosensor, Anal. Chim. Acta, 231, 33, 10.1016/S0003-2670(00)86394-1 · DOI
  57. Jin, 2001, Glucose sensing based on interdigitated array microelectrode, Anal. Sci., 17, 841, 10.2116/analsci.17.841 · doi:10.2116/analsci.17.841
  58. Marrakchi, 2008, Conductometric biosensor based on glucose oxidase and β-galactosidase for specific lactose determination in milk, Mater. Sci. Eng. C, 28, 872, 10.1016/j.msec.2007.10.046 · doi:10.1016/j.msec.2007.10.046
  59. Sergeyeva, 1999, Hydrogen peroxide–Sensitive enzyme sensor based on phthalocyanine thin film, Anal. Chim. Acta, 391, 289, 10.1016/S0003-2670(99)00203-2 · doi:10.1016/s0003-2670(99)00203-2
  60. Dzyadevych, 2002, Assessment of the toxicity of methyl parathion and its photodegradation products in water samples using conductometric enzyme biosensors, Anal. Chim. Acta, 459, 33, 10.1016/S0003-2670(02)00083-1 · doi:10.1016/s0003-2670(02)00083-1
  61. Dzyadevych, 2002, A comparative photodegradation studies of methyl parathion by using Lumistox test and conductometric biosensor technique, Mater. Sci. Eng. C, 21, 55, 10.1016/S0928-4931(02)00058-9 · doi:10.1016/s0928-4931(02)00058-9
  62. Martelet, 1994, Enzyme biosensor based on a micromachined interdigitated conductometric transducer: application to the detection of urea, glucose, acetyl- and butyrylcholine chlordes, Sens. Actuators B Chem., 21, 123, 10.1016/0925-4005(94)80013-8 · doi:10.1016/0925-4005(94)80013-8
  63. Dzydevich, 1994, Conductometric biosensors based on cholinesterases for sensitive detection of pesticides, Electroanalysis, 6, 752, 10.1002/elan.1140060907 · doi:10.1002/elan.1140060907
  64. Arkhypova, 2001, Multibiosensor based on enzyme inhibition analysis for determination of different toxic substances, Talanta, 55, 919, 10.1016/S0039-9140(01)00495-7 · doi:10.1016/s0039-9140(01)00495-7
  65. Rodriguez, 2002, Conductometric uric acid and urea biosensor prepared from electroconductive polyaniline–poly(n-butyl methacrylate) composites, Sens. Actuators B Chem., 85, 19, 10.1016/S0925-4005(02)00045-X · doi:10.1016/s0925-4005(02)00045-x
  66. Dzyadevych, 2001, Conductometric formaldehyde sensitive biosensor with specifically adapted analytical characteristics, Anal. Chim. Acta, 445, 47, 10.1016/S0003-2670(01)01249-1 · doi:10.1016/s0003-2670(01)01249-1
  67. Anh, 2004, Conductometric tyrosinase biosensor for the detection of diuron, atrazine and its main metabolites, Talanta, 63, 365, 10.1016/j.talanta.2003.11.008 · doi:10.1016/j.talanta.2003.11.008
  68. Dzyadevych, 2005, Early-warning electrochemical biosensor system for environmental monitoring based on enzyme inhibition, Sens. Actuators B Chem., 105, 81, 10.1016/S0925-4005(04)00115-7 · DOI
  69. Shervedani, 2006, A novel method for glucose determination based on electrochemical impedance spectroscopy using glucose oxidase self-assembled biosensor, Bioelectrochemistry, 69, 201, 10.1016/j.bioelechem.2006.01.003 · DOI · Paper page
  70. Zehani, 2014, Sensitive impedimetric biosensor for direct detection of diazinon based on lipases, Front. Chem., 2, 1, 10.3389/fchem.2014.00044 · doi:10.3389/fchem.2014.00044
  71. Chan, 2017, l-lactate selective impedimetric bienzymatic biosensor based on lactate dehydrogenase and pyruvate oxidase, Electrochim. Acta, 231, 209, 10.1016/j.electacta.2017.02.050 · doi:10.1016/j.electacta.2017.02.050
  72. Shamsipur, 2012, A novel impedimetric nanobiosensor for low level determination of hydrogen peroxide based on biocatalysis of catalase, Bioelectrochemistry, 83, 31, 10.1016/j.bioelechem.2011.08.003 · doi:10.1016/j.bioelechem.2011.08.003
  73. Zane, 2011, An impedimetric glucose biosensor based on overoxidized polypyrrole thin film, Electroanalysis, 23, 1134, 10.1002/elan.201000576 · doi:10.1002/elan.201000576
  74. Maalouf, 2007, Amperometric and impedimetric characterization of a glutamate biosensor based on Nafion® and a methyl viologen modified glassy carbon electrode, Biosens. Bioelectron., 22, 2682, 10.1016/j.bios.2006.11.003 · DOI
  75. Myler, 2005, Sonochemically fabricated microelectrode arrays for biosensors: Part III. AC impedimetric study of aerobic and anaerobic response of alcohol oxidase within polyaniline, Biosens. Bioelectron., 21, 666, 10.1016/j.bios.2004.12.012 · doi:10.1016/j.bios.2004.12.012
  76. Bouyahia, 2011, Impedance spectroscopy and conductometric biosensing for probing catalase reaction with cyanide as ligand and inhibitor, Bioelectrochemistry, 80, 155, 10.1016/j.bioelechem.2010.07.006 · doi:10.1016/j.bioelechem.2010.07.006
  77. Cortina, 2006, Urea impedimetric biosensor based on polymer degradation onto interdigitated electrodes, Sens. Actuators B Chem., 118, 84, 10.1016/j.snb.2006.04.062 · doi:10.1016/j.snb.2006.04.062
  78. Abdelmalek, 2001, Ellipsometry measurements and impedance spectroscopy on Langmuir-Blodgett membranes on Si/SiO2 for ion sensitive sensor, Sens. Actuators B Chem., 72, 208, 10.1016/S0925-4005(00)00657-2 · DOI
  79. Free, 1957, Simple specific test for urine glucose, Clin. Chem., 3, 163, 10.1093/clinchem/3.3.163 · DOI
  80. Sanz, 2007, A reagentless optical biosensor based on the intrinsic absorption properties of peroxidase, Biosens. Bioelectron., 22, 956, 10.1016/j.bios.2006.04.008 · doi:10.1016/j.bios.2006.04.008
  81. Sanz, 2007, Direct glucose determination in blood using a reagentless optical biosensor, Biosens. Bioelectron., 22, 2876, 10.1016/j.bios.2006.12.015 · doi:10.1016/j.bios.2006.12.015
  82. Lan, 2012, Development of a novel optical biosensor for detection of organophoshorus pesticides based on methyl parathion hydrolase immobilized by metal-chelate affinity, Sensors, 12, 8477, 10.3390/s120708477 · doi:10.3390/s120708477
  83. Choi, 2001, Optical organophosphorus biosensor consisting of acetylcholinesterase/viologen hetero Langmuir-Blodgett film, Biosens. Bioelectron., 16, 937, 10.1016/S0956-5663(01)00213-5 · doi:10.1016/s0956-5663(01)00213-5
  84. Wang, 2003, Flow injection amperometric detection of OP nerve agents based on an organophosphorus-hydrolase biosensor detector, Biosens. Bioelectron., 18, 255, 10.1016/S0956-5663(02)00178-1 · DOI
  85. Rosa, 2002, Optical biosensor based on nitrite reductase immobilised in controlled pore glass, Biosens. Bioelectron., 17, 45, 10.1016/S0956-5663(01)00263-9 · DOI
  86. Nguyen, 2018, On-chip fluorescence switching system for constructing a rewritable random access data storage device, Sci. Rep., 8, 337, 10.1038/s41598-017-16535-7 · DOI
  87. Andreu, 2001, Intrinsic fluorescence of enzymes and fluorescence of chemically modified enzymes for analytical purposes: A review, Luminescence, 16, 199, 10.1002/bio.633 · doi:10.1002/bio.633
  88. Hussain, 2005, Glucose sensing based on the intrinsic fluorescence of sol-gel immobilized yeast hexokinase, Anal. Biochem., 339, 137, 10.1016/j.ab.2005.01.016 · DOI
  89. Maity, 2000, Time-resolved fluorescence of tryptophans in yeast hexokinase-PI: effect of subunit dimerization and ligand binding, J. Photochem. Photobiol. B, 55, 20, 10.1016/S1011-1344(00)00019-1 · DOI
  90. Portaccio, 2009, Fiber-optic glucose biosensor based on glucose oxidase immobilised in a silica gel matrix, J. Solgel Sci. Technol., 50, 437, 10.1007/s10971-009-1915-4 · DOI
  91. Sierra, 1998, Fluorimetric-enzymatic determination of glucose based on labelled glucose oxidase, Anal. Chim. Acta, 368, 97, 10.1016/S0003-2670(98)00197-4 · doi:10.1016/s0003-2670(98)00197-4
  92. Sanz, 2003, Fluorometric sensors based on chemically modified enzymes glucose determination in drinks, Talanta, 60, 415, 10.1016/S0039-9140(03)00075-4 · DOI
  93. Sierra, 2000, Direct determination of glucose in serum by fluorimetry using a labeled enzyme, Anal. Chim. Acta, 414, 33, 10.1016/S0003-2670(00)00831-X · DOI
  94. Sierra, 2000, Direct fluorometric determination of total cholesterol in serum using derivatized cholesterol oxidase, Appl. Spectrosc., 54, 1157, 10.1366/0003702001950968 · doi:10.1366/0003702001950968
  95. Andreu, 2002, Study of a fluorometric-enzymatic method for bilirubin based on chemically modified bilirubin-oxidase and multivariate calibration, Talanta, 57, 343, 10.1016/S0039-9140(02)00023-1 · doi:10.1016/s0039-9140(02)00023-1
  96. Hartnett, 1999, Kinetics and thermodynamics of free flavins and the flavin-based redox active site within glucose oxidase dissolved in solution or sequestered within a sol−gel-derived glass, Anal. Chem., 71, 1215, 10.1021/ac981083t · DOI
  97. Zhu, 2011, An enzymatic colorimetric assay for glucose-6-phosphate, Anal. Biochem., 419, 266, 10.1016/j.ab.2011.08.037 · DOI
  98. Gessei, 2015, A fiber-optic sorbitol biosensor based on NADH fluorescence detection toward rapid diagnosis of diabetic complications, Analyst, 140, 6335, 10.1039/C4AN01593B · doi:10.1039/c4an01593b
  99. Cordek, 1999, Direct immobilization of glutamate dehydrogenase on optical fiber probes for ultrasensitive glutamate detection, Anal. Chem., 71, 1529, 10.1021/ac980850l · DOI
  100. Thompson, 1993, Enzyme-based fiber optic zinc biosensor, Anal. Chem., 65, 730, 10.1021/ac00054a013 · DOI
  101. Yang, V.C., and Ngo, T.T. (2000). Luminescent biosensors. Biosensors and Their Applications, Springer. · doi:10.1007/978-1-4615-4181-3
  102. Klimant, 1994, Novel metal-organic ruthenium(II) diimin complexes for use as longwave excitable luminescent oxygen probes, Talanta, 41, 985, 10.1016/0039-9140(94)E0051-R · doi:10.1016/0039-9140(94)e0051-r
  103. Papkovsky, 1998, Biosensors on the basis of luminescent oxygen sensor: The use of microporous light-scattering support materials, Sens. Actuators B Chem., 51, 137, 10.1016/S0925-4005(98)00171-3 · doi:10.1016/s0925-4005(98)00171-3
  104. Andrus, 2015, Characterization of lactate sensors based on lactate oxidase and palladium benzoporphyrin immobilized in hydrogels, Biosensors, 5, 398, 10.3390/bios5030398 · DOI
  105. Scully, 2007, Optical fibre biosensors using enzymatic transducers to monitor glucose, Meas. Sci. Technol., 18, 3177, 10.1088/0957-0233/18/10/S20 · doi:10.1088/0957-0233/18/10/s20
  106. Gautier, 1990, Fibre-optic biosensor based on luminescence and immobilized enzymes: Microdetermination of sorbitol, ethanol and oxaloacetate, J. Biolumin. Chemilumin., 5, 57, 10.1002/bio.1170050112 · doi:10.1002/bio.1170050112
  107. Li, 2008, Chemiluminescence flow-through biosensor for glucose with eggshell membrane as enzyme immobilization platform, Anal. Biochem., 374, 64, 10.1016/j.ab.2007.10.036 · doi:10.1016/j.ab.2007.10.036
  108. Ramos, 2001, Enhanced chemiluminescence biosensor for the determination of phenolic compounds and hydrogen peroxide, Sens. Actuators B Chem., 73, 71, 10.1016/S0925-4005(00)00681-X · DOI
  109. Cattaneo, 1993, Monitoring glutamine in animal cell cultures using a chemiluminescence fiber optic biosensor, Biotechnol. Bioeng., 41, 659, 10.1002/bit.260410609 · DOI
  110. Freeman, 1978, Chemiluminescence fiber optic probe for hydrogen peroxide based on the luminol reaction, Anal. Chem., 50, 1242, 10.1021/ac50031a012 · DOI
  111. Syshchyk, 2015, Enzyme biosensor systems based on porous silicon photoluminescence for detection of glucose, urea and heavy metals, Biosens. Bioelectron., 66, 89, 10.1016/j.bios.2014.10.075 · DOI
  112. Nguyen, 2015, Surface Plasmon Resonance: A versatile technique for biosensor applications, Sensors, 15, 10481, 10.3390/s150510481 · DOI · Paper page
  113. Fong, 2002, Study of substrate-enzyme interaction between immobilized pyridoxamine and recombinant porcine pyridoxal kinase using surface plasmon resonance biosensor, Biochim. Biophys. Acta Proteins Struct. Mol. Enzymol., 1596, 95, 10.1016/S0167-4838(02)00208-X · DOI
  114. Jabbari, 2017, A novel enzyme based SPR-biosensor to detect bromocriptine as an ergoline derivative drug, Sens. Actuators B Chem., 240, 519, 10.1016/j.snb.2016.08.165 · DOI
  115. Milkani, 2011, Direct detection of acetylcholinesterase inhibitor binding with an enzyme-based surface plasmon resonance sensor, Anal. Biochem., 408, 212, 10.1016/j.ab.2010.09.009 · doi:10.1016/j.ab.2010.09.009
  116. Miyazaki, 2017, Surface plasmon resonance biosensor for enzymatic detection of small analytes, Nanotechnology, 28, 145501, 10.1088/1361-6528/aa6284 · doi:10.1088/1361-6528/aa6284
  117. Arya, 2007, Poly-(3-hexylthiophene) self-assembled monolayer based cholesterol biosensor using surface plasmon resonance technique, Biosens. Bioelectron., 22, 2516, 10.1016/j.bios.2006.10.011 · doi:10.1016/j.bios.2006.10.011
  118. Kang, 2001, A novel electrochemical SPR biosensor, Electrochem. commun., 3, 489, 10.1016/S1388-2481(01)00170-9 · DOI
  119. Geitmann, 2004, Studies of substrate-induced conformational changes in human cytomegalovirus protease using optical biosensor technology, Anal. Biochem., 332, 203, 10.1016/j.ab.2004.06.008 · doi:10.1016/j.ab.2004.06.008
  120. Mishra, 2014, Flow injection analysis biosensor for urea analysis in urine using enzyme thermistor, Appl. Biochem. Biotechnol., 174, 998, 10.1007/s12010-014-0985-0 · DOI
  121. Mattiasson, 1977, Thermometric enzyme linked immunosorbent assay: TELISA, Biochim. Biophys. Acta, 483, 221, 10.1016/0005-2744(77)90050-X · doi:10.1016/0005-2744(77)90050-x
  122. Scheper, 1993, Two FIA-based biosensor systems studied for bioprocess monitoring, J. Biotechnol., 31, 345, 10.1016/0168-1656(93)90079-3 · DOI
  123. Yakovleva, 2013, The enzyme thermistor—A realistic biosensor concept. A critical review, Anal. Chim. Acta, 766, 1, 10.1016/j.aca.2012.12.004 · DOI
  124. Yang, 2007, Piezoelectric urea biosensor based on immobilization of urease onto nanoporous alumina membranes, Biosens. Bioelectron., 22, 3283, 10.1016/j.bios.2007.03.006 · doi:10.1016/j.bios.2007.03.006
  125. Seker, 2010, Electrospun nanofibrous PLGA/fullerene-C60 coated quartz crystal microbalance for real-time gluconic acid monitoring, IEEE Sens. J., 10, 1342, 10.1109/JSEN.2010.2043670 · doi:10.1109/jsen.2010.2043670
  126. Abad, 1998, Determination of organophosphorus and carbamate pesticides using a piezoelectric biosensor, Anal. Chem., 70, 2848, 10.1021/ac971374m · DOI · Paper page
  127. Alfonta, 2000, Sensing of acetylcholine by a tricomponent-enzyme layered electrode using faradaic impedance spectroscopy, cyclic voltammetry, and microgravimetric quartz crystal microbalance transduction methods, Anal. Chem., 72, 927, 10.1021/ac990439d · doi:10.1021/ac990439d
  128. Karousos, 2002, Quartz crystal microbalance determination of organophosphorus and carbamate pesticides, Anal. Chim. Acta, 469, 189, 10.1016/S0003-2670(02)00668-2 · doi:10.1016/s0003-2670(02)00668-2
  129. 2015, Detection of hydrogen peroxide and glucose by enzyme product precipitation on sensor surface, Chem. Pap., 69, 167
  130. Martin, 2003, Enzyme-based determination of cholesterol using the quartz crystal acoustic wave sensor, Anal. Chim. Acta, 487, 91, 10.1016/S0003-2670(03)00504-X · doi:10.1016/s0003-2670(03)00504-x
  131. Tang, 2016, Acetylcholinesterase-reduced graphene oxide hybrid films for organophosphorus neurotoxin sensing via quartz crystal microbalance, Chem. Phys. Lett., 660, 199, 10.1016/j.cplett.2016.08.025 · DOI
  132. Marty, 2009, A review of the use of genetically engineered enzymes in electrochemical biosensors, Semin. Cell Dev. Biol., 20, 3, 10.1016/j.semcdb.2009.01.009 · doi:10.1016/j.semcdb.2009.01.009
  133. Nguyen, H.H., Park, J., Park, S.J., Lee, C.-S., Hwang, S., Shin, Y.-B., Ha, T.H., and Kim, M. (2018). Long-term stability and integrity of plasmid-based DNA data storage. Polymers, 10. · DOI
  134. Istamboulie, 2007, Highly sensitive detection of organophosphorus insecticides using magnetic microbeads and genetically engineered acetylcholinesterase, Biosens. Bioelectron., 23, 506, 10.1016/j.bios.2007.06.022 · doi:10.1016/j.bios.2007.06.022
  135. Sotiropoulou, 2005, Genetically engineered acetylcholinesterase-based biosensor for attomolar detection of dichlorvos, Biosens. Bioelectron., 20, 2347, 10.1016/j.bios.2004.08.026 · doi:10.1016/j.bios.2004.08.026
  136. Boublik, 2002, Acetylcholinesterase engineering for detection of insecticide residues, Protein Eng., 15, 43, 10.1093/protein/15.1.43 · DOI
  137. Yamazaki, 2000, Extended-range glucose sensor employing engineered glucose dehydrogenases, Anal. Chem., 72, 4689, 10.1021/ac000151k · DOI
  138. Moore, 1996, Electrocatalytic reduction of organic peroxides in organic solvents by microperoxidase-11 immobilized as a monolayer on a gold electrode, J. Electroanal. Chem., 417, 189, 10.1016/S0022-0728(96)04736-5 · doi:10.1016/s0022-0728(96)04736-5
  139. Behera, 2007, Mercaptoethylpyrazine promoted electrochemistry of redox protein and amperometric biosensing of uric acid, Biosens. Bioelectron., 23, 556, 10.1016/j.bios.2007.06.012 · doi:10.1016/j.bios.2007.06.012
  140. Niu, 2017, Novel fluorescence-based biosensors incorporating unnatural amino acids, Methods Enzymol., 589, 191, 10.1016/bs.mie.2017.01.012 · DOI
  141. Kaumaya, P. (2012). Protein engineering with non-natural amino acids. Protein Engineering, InTech. · doi:10.5772/1286
  142. Ugwumba, 2011, Improving a natural enzyme activity through incorporation of unnatural amino acids, J. Am. Chem. Soc., 133, 326, 10.1021/ja106416g · DOI
  143. Abad, 2000, Modulation of electroenzymatic NADPH oxidation through oriented immobilization of ferredoxin:NADP+ reductase onto modified gold electrodes, J. Am. Chem. Soc., 122, 9808, 10.1021/ja001365m · DOI
  144. Andreescu, 2001, Immobilization of enzymes on screen-printed sensors via an histidine tail. Application to the detection of pesticides using modified cholinesterase, Anal. Lett., 34, 529, 10.1081/AL-100002593 · doi:10.1081/al-100002593
  145. Kapp, 2006, Electrochemical and sensorial behavior of SOD mutants immobilized on gold electrodes in aqueous/organic solvent mixtures, Electroanalysis, 18, 1909, 10.1002/elan.200603620 · doi:10.1002/elan.200603620
  146. Uematsu, 2014, Promotion and suppression effects of cationic polymer ε-poly-L-lysine on the glucose oxidase reaction with ferrocene derivatives as oxidants with different charges, Anal. Sci., 30, 299, 10.2116/analsci.30.299 · doi:10.2116/analsci.30.299
  147. Zhou, 2001, Construction of a fusion enzyme system by gene splicing as a new molecular recognition element for a sequence biosensor, Bioconjug. Chem., 12, 924, 10.1021/bc015509d · doi:10.1021/bc015509d
  148. Chen, 2002, Genetic modification of glucose oxidase for improving performance of an amperometric glucose biosensor, Biosens. Bioelectron., 17, 851, 10.1016/S0956-5663(02)00051-9 · DOI
  149. Rodrigues, 2011, Coupling chemical modification and immobilization to improve the catalytic performance of enzymes, Adv. Synth. Catal., 353, 2216, 10.1002/adsc.201100163 · DOI · Paper page
  150. Joubert, 2010, Protein chemical modification on endogenous amino acids, Chem. Biol., 17, 213, 10.1016/j.chembiol.2010.02.008 · DOI · Paper page
  151. Davis, 2003, Chemical modification of biocatalysts, Curr. Opin. Biotechnol., 14, 379, 10.1016/S0958-1669(03)00098-3 · DOI · Paper page
  152. Liu, 2011, Diels–Alder Cycloaddition for fluorophore targeting to specific proteins inside living cells, J. Am. Chem. Soc., 134, 792, 10.1021/ja209325n · DOI · Paper page
  153. Chalker, 2009, Chemical modification of proteins at cysteine: Opportunities in chemistry and biology, Chem. Asian J., 4, 630, 10.1002/asia.200800427 · DOI · Paper page
  154. Groups, 1975, Chemical modification of amino groups and guanidino groups of trypsin, Biochem. J., 147, 71, 10.1042/bj1470071 · doi:10.1042/bj1470071
  155. Li, 2000, A new ligation method for N-terminal tryptophan-containing peptides using the Pictet–Spengler reaction, Tetrahedron Lett., 41, 4069, 10.1016/S0040-4039(00)00592-X · DOI
  156. Dawson, 1994, Synthesis of proteins by native chemical ligation, Science, 266, 776, 10.1126/science.7973629 · DOI · Paper page
  157. Tam, 1999, Orthogonal ligation strategies for peptide and protein, Biopolymers, 51, 311, 10.1002/(SICI)1097-0282(1999)51:5<311::AID-BIP2>3.0.CO;2-A · DOI
  158. Geoghegan, 1992, Site-directed conjugation of nonpeptide groups to peptides and proteins via periodate oxidation of a 2-amino alcohol. Application to modification at N-terminal serine, Bioconjug. Chem., 3, 138, 10.1021/bc00014a008 · DOI · Paper page
  159. 2003, Enzyme stabilization—recent experimental progress, Enzyme Microb. Technol., 33, 137, 10.1016/S0141-0229(03)00160-1 · DOI · Paper page
  160. Palomo, 2007, Modulation of immobilized lipase enantioselectivity via chemical amination, Adv. Synth. Catal., 349, 1119, 10.1002/adsc.200600555 · doi:10.1002/adsc.200600555
  161. Khajeh, 2001, Chemical modification of lysine residues in Bacillus a-amylases: effect on activity and stability, Enzyme Microb. Technol., 28, 543, 10.1016/S0141-0229(01)00296-4 · doi:10.1016/s0141-0229(01)00296-4
  162. Sangeetha, 2006, Chemical modification of papain for use in alkaline medium, J. Mol. Catal. B Enzym., 38, 171, 10.1016/j.molcatb.2006.01.003 · DOI
  163. Migneault, 2004, Glutaraldehyde: Behavior in aqueous solution, reaction with proteins, and application to enzyme crosslinking, Biotechniques, 37, 790, 10.2144/04375RV01 · DOI · Paper page
  164. Torchilin, 1979, Principles of enzyme stabilization V. The possibility of enzyme selfstabilization under the action of potentially reversible intramolecular cross-linkages of different length, Biochim. Biophys. Acta–Enzymol., 568, 1, 10.1016/0005-2744(79)90267-5 · doi:10.1016/0005-2744(79)90267-5
  165. Reiner, 1977, Chemical modification of enzymes II. Conformational stability of cross-linked bovine pancreatic ribonuclease, J. Mol. Catal., 1, 3, 10.1016/0304-5102(75)80002-2 · doi:10.1016/0304-5102(75)80002-2
  166. Herzig, 1964, Bifunctional reagents and protein structure determination. The reaction of phenolic disulfonyl chlorides with lysozyme, Biopolymers, 2, 349, 10.1002/bip.1964.360020406 · doi:10.1002/bip.1964.360020406
  167. Cowan, 2011, Enhancing the functional properties of thermophilic enzymes by chemical modification and immobilization, Enzyme Microb. Technol., 49, 326, 10.1016/j.enzmictec.2011.06.023 · DOI · Paper page
  168. Torchilin, 1984, Stabilization of subunit enzymes by intramolecular crosslinking with bifunctional reagents, Ann. N. Y. Acad. Sci., 434, 27, 10.1111/j.1749-6632.1984.tb29795.x · doi:10.1111/j.1749-6632.1984.tb29795.x
  169. Kim, 2003, Stability and activity of cross-linked enzyme crystals of cyclodextrin glucanotransferase isolated from Bacillus macerans, J. Mol. Catal. B Enzym., 26, 287, 10.1016/j.molcatb.2003.07.007 · doi:10.1016/j.molcatb.2003.07.007
  170. Cui, J.D., Li, L.L., and Bian, H.J. (2013). Immobilization of cross-linked phenylalanine ammonia lyase aggregates in microporous silica gel. PLoS One, 8. · doi:10.1371/journal.pone.0080581
  171. Cao, 2002, Cross-linked enzyme aggregates with enhanced activity: Application to lipases, Biotechnol. Lett., 24, 1379, 10.1023/A:1019863314646 · DOI · Paper page
  172. 2013, Polymer directed protein assemblies, Polymers, 5, 576, 10.3390/polym5020576 · DOI
  173. Romero, 2012, Semisynthetic peptide–lipase conjugates for improved biotransformations, Chem. Commun., 48, 9053, 10.1039/c2cc34816k · doi:10.1039/c2cc34816k
  174. Bolivar, 2009, Coating of soluble and immobilized enzymes with ionic polymers: Full stabilization of the quaternary structure of multimeric enzymes, Biomacromolecules, 10, 742, 10.1021/bm801162e · DOI
  175. Nakashima, 2006, Homogeneous enzymatic reactions in ionic liquids with poly(ethylene glycol)-modified subtilisin, Org. Biomol. Chem., 4, 3462, 10.1039/b608920h · DOI
  176. Gupta, 2004, Enzymes in organic media: Forms, functions and applications, Eur. J. Biochem., 271, 2575, 10.1111/j.1432-1033.2004.04163.x · DOI · Paper page
  177. Takahashi, 1984, Polyethylene glycol-modified enzymes trap water on their surface and exert enzymic activity in organic solvents, Biotechnol. Lett., 6, 765, 10.1007/BF00134715 · doi:10.1007/bf00134715
  178. Altikatoglu, 2010, Glucose oxidase-dextran conjugates with enhanced stabilities against temperature and pH, Appl. Biochem. Biotechnol., 160, 2187, 10.1007/s12010-009-8812-8 · DOI
  179. Wollenberger, 1993, Enhancing biosensor performance using multienzyme systems, Trends Biotechnol., 11, 255, 10.1016/0167-7799(93)90137-X · doi:10.1016/0167-7799(93)90137-x
  180. Muschiol, 2015, Cascade catalysis–strategies and challenges en route to preparative synthetic biology, Chem. Commun., 51, 5798, 10.1039/C4CC08752F · DOI · Paper page
  181. Bongiovanni, 2001, An electrochemical multienzymatic biosensor for determination of cholesterol, Bioelectrochemistry, 54, 17, 10.1016/S0302-4598(01)00105-2 · DOI
  182. Fang, 2016, A novel bi-enzyme electrochemical biosensor for selective and sensitive determination of methyl salicylate, Biosens. Bioelectron., 81, 39, 10.1016/j.bios.2016.01.095 · doi:10.1016/j.bios.2016.01.095
  183. Mansor, N.N.N., Leong, T.T., Safitri, E., Futra, D., Ahmad, N.S., Nasuruddin, D.N., Itnin, A., Zaini, I.Z., Arifin, K.T., and Heng, L.Y. (2018). An amperometric biosensor for the determination of bacterial sepsis biomarker, secretory phospholipase group 2-IIA using a tri-enzyme system. Sensors, 18. · doi:10.3390/s18030686
  184. 2015, Novel Amperometric Tri-enzyme biosensor for lysine determination in pharmaceutical products and food samples, Electroanalysis, 27, 817, 10.1002/elan.201400600 · DOI
  185. Hamid, 1989, Flow-through multi-enzyme electrodes for the determination of lactose, Analyst, 114, 1587, 10.1039/an9891401587 · doi:10.1039/an9891401587

Cited by

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Metadata

Authors
Nguyen, H. H., Lee, S. H., Lee, U. J., Fermin, C. D., & Kim, M.
Venue
Materials
Publisher
MDPI AG
Published
2019-01-02
Volume
12
Issue
1
Pages
121
ISSN
1996-1944 (ISSN-L)
DOI
10.3390/ma12010121
OpenAlex
W2906905739
Cited by
606
References
2
FWCI
23.62
Type
journal article
Language
en
Open access
gold
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
Korea Research Institute of Bioscience and Biotechnology (KRIBB Initiative Program)

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Nguyen, H. H., Lee, S. H., Lee, U. J., Fermin, C. D., & Kim, M. (2019). Immobilized Enzymes in Biosensor Applications. Materials. https://doi.org/10.3390/ma12010121

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