Low Glycemic Index Prototype Isomaltulose—Update of Clinical Trials
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Low glycemic index diets are supposed to achieve a more beneficial effect on blood glucose control in people with diabetes mellitus and may also provide metabolic benefits for the general population. A prototype of a low-glycemic index carbohydrate is the natural occurring disaccharide isomaltulose that can be commercially produced from sucrose (beet sugar) to industrial scale. It is currently used in various food and drink applications as well as special and clinical nutrition feeds and formula diet as a food ingredient and alternative sugar. Here we provide an overview on clinical trials with isomaltulose including an analysis of its effects on glycemia and fat oxidation as compared to high glycemic index sugars and carbohydrates. In addition, we discuss recent reports on beneficial effects in weight-loss maintenance and pregnancy.
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Current evidence suggests that low glycemic and low insulinemic properties of non-starch slowly digestible carbohydrates appear of particular interest in sports nutrition and cognitive performance.
“Therefore, current evidence suggests that low glycemic and low insulinemic properties of non-starch slowly digestible carbohydrates appear of a particular interest in sports nutrition and cognitive performance [55,56].”
From The 4R’s Framework of Nutritional Strategies for Post-Exercise Recovery: A Review with Emphasis on New Generation of Carbohydrates (2020) · cites this paper as [55]
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- Authors
- Maresch, C. C., Petry, S. F., Theis, S., Bosy-Westphal, A., & Linn, T.
- Affiliations
- Justus-Liebig-Universität Gießen (DE)
- BENEO-Institute, 67283 Obrigheim/Pfalz, Germany
- Applied Nutritional Science/Dietetics, University of Hohenheim, 70599 Stuttgart, Baden-Württemberg, Germany
- Corresponding author
- Linn, Thomas
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2017-04-13
- Volume
- 9
- Issue
- 4
- Pages
- 381
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC5409720
- OpenAlex
- W2605744918
- Cited by
- 53
- References
- 61
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 7 · 2023: 9 · 2022: 10 · 2021: 8 · 2020: 6 · 2019: 2 · 2018: 2 · 2017: 1
- FWCI
- 0.44
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Bundesministerium für Wissenschaft und Forschung (01DL13015, 01EA1336)
- Deutsche Forschungsgemeinschaft (LI 353/17-1, BO 3296/1-1)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- isomaltulose, low glycemic index, glycemic index, glycemic control, diabetes mellitus, fat oxidation, sucrose, weight loss maintenance, pregnancy, clinical trials
- MeSH terms
- Body Weight Maintenance, Clinical Trials as Topic, Cognition, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diet, Diabetic, Diet, Reducing, Female, Humans, Hyperglycemia, Isomaltose, Male, Pregnancy, Pregnancy Complications, Glycemic Index, Overweight, Athletic Performance, Weight Reduction Programs, Sports Nutritional Physiological Phenomena, Nutritive Sweeteners
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