Real-Time Quality Index to Control Data Loss in Real-Life Cardiac Monitoring Applications
Open accessPublished version of a preprint
Abstract
Wearable cardiac sensors pave the way for advanced cardiac monitoring applications based on heart rate variability (HRV). In real-life settings, heart rate (HR) measurements are subject to motion artifacts that may lead to frequent data loss (missing samples in the HR signal), especially for commercial devices based on photoplethysmography (PPG). The current study had two main goals: (i) to provide a white-box quality index that estimates the amount of missing samples in any piece of HR signal; and (ii) to quantify the impact of data loss on feature extraction in a PPG-based HR signal. This was done by comparing real-life recordings from commercial sensors featuring both PPG (Empatica E4) and ECG (Zephyr BioHarness 3). After an outlier rejection process, our quality index was used to isolate portions of ECG-based HR signals that could be used as benchmark, to validate the output of Empatica E4 at the signal level and at the feature level. Our results showed high accuracy in estimating the mean HR (median error: 3.2%), poor accuracy for short-term HRV features (e.g., median error: 64% for high-frequency power), and mild accuracy for longer-term HRV features (e.g., median error: 25% for low-frequency power). These levels of errors could be reduced by using our quality index to identify time windows with few or no data loss (median errors: 0.0%, 27%, and 6.4% respectively, when no sample was missing). This quality index should be useful in future work to extract reliable cardiac features in real-life measurements, or to conduct a field validation study on wearable cardiac sensors.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The Empatica E4 may be unsuited for monitoring everyday activities.
“The device has also been evaluated in general purpose real-world settings, with results indicating that the Empatica E4 may be unsuited for monitoring everyday activities70,71.”
From Data quality evaluation in wearable monitoring (2022) · cites this paper as [70]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
A Real-Time QRS Detection Algorithm
Pan, J., & Tompkins, W. J. (1985) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1985.325532 · Cited by 7,855 · see citing works
Picard, R. W. (1997) · MIT Press · doi:10.7551/mitpress/1140.001.0001 · Cited by 7,382 · see citing works
An overview of heart rate variability metrics and norms
Shaffer, F., & Ginsberg, J. P. (2017) · Frontiers in Public Health · doi:10.3389/fpubh.2017.00258 · Cited by 7,185 · see citing works
Least-squares frequency analysis of unequally spaced data
Lomb, N. (1976) · Astrophysics and Space Science · doi:10.1007/bf00648343 · Cited by 5,724 · see citing works
A Survey Method for Characterizing Daily Life Experience: The Day Reconstruction Method
Kahneman, D., Krueger, A. B., Schkade, D. A., Schwarz, N., & Stone, A. A. (2004) · Science · doi:10.1126/science.1103572 · Cited by 3,422 · see citing works
Heart rate variability: A review
Rajendra Acharya, U., Paul Joseph, K., Kannathal, N., Lim, C. M., & Suri, J. S. (2006) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-006-0119-0 · Cited by 2,820 · see citing works
Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature
Kim, H.-G., Cheon, E.-J., Bai, D.-S., Lee, Y. H., & Koo, B.-H. (2018) · Psychiatry Investigation · doi:10.30773/pi.2017.08.17 · Cited by 2,308 · see citing works
Understanding the Lomb–Scargle Periodogram
Vanderplas, J. (2018) · The Astrophysical Journal Supplement Series · doi:10.3847/1538-4365/aab766 · Cited by 1,262 · see citing works
Karantonis, D. M., Narayanan, M. R., Mathie, M. J., Lovell, N. H., & Celler, B. G. (2006) · IEEE Transactions on Information Technology in Biomedicine · doi:10.1109/titb.2005.856864 · Cited by 1,239 · see citing works
The Quantified Self: Fundamental Disruption in Big Data Science and Biological Discovery
Swan, M. (2013) · Big Data · doi:10.1089/big.2012.0002 · Cited by 931 · see citing works
Bouten, C. V. C., Koekkoek, K. K., Verduin, M., Kodde, R., & Janssen, J. J. (1997) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.554760 · Cited by 911 · see citing works
How accurate is pulse rate variability as an estimate of heart rate variability?
Schäfer, A., & Vagedes, J. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.03.119 · Cited by 661 · cited 2× · see citing works
“However, HRV parameters have also shown substantial deviations between PPG and ECG under the influence of moderate mental effort or wrist activity [14].”
MethodPulse oximetry: Principles and limitations
Sinex, J. E. (1999) · The American Journal of Emergency Medicine · doi:10.1016/s0735-6757(99)90019-0 · Cited by 482 · see citing works
Gil, E., Orini, M., Bailón, R., Vergara, J. M., Mainardi, L., & Laguna, P. (2010) · Physiological Measurement · doi:10.1088/0967-3334/31/9/015 · Cited by 461 · see citing works
Axisa, F., Schmitt, P. M., Géhin, C., Delhomme, G., McAdams, E. T., & Dittmar, A. (2005) · IEEE Transactions on Information Technology in Biomedicine · doi:10.1109/titb.2005.854505 · Cited by 410 · see citing works
Orphanidou, C., Bonnici, T., Charlton, P., Clifton, D., Vallance, D., & Tarassenko, L. (2014) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2014.2338351 · Cited by 368 · see citing works
Detecting Vital Signs with Wearable Wireless Sensors
Yilmaz, T., Foster, R., & Hao, Y. (2010) · Sensors · doi:10.3390/s101210837 · Cited by 341 · see citing works
Nonlinear analysis of complex phenomena in cardiological data
Wessel, N., Voss, A., Malberg, H., Ziehmann, C., Voss, H. U., Schirdewan, A., Meyerfeldt, U., & Kurths, J. (2000) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s003990070035 · Cited by 292 · see citing works
Dynamic time warping and machine learning for signal quality assessment of pulsatile signals
Li, Q., & Clifford, G. D. (2012) · Physiological Measurement · doi:10.1088/0967-3334/33/9/1491 · Cited by 274 · see citing works
Novel dry electrodes for ECG monitoring
Gruetzmann, A., Hansen, S., & Müller, J. (2007) · Physiological Measurement · doi:10.1088/0967-3334/28/11/005 · Cited by 248 · see citing works
Greene, S., Thapliyal, H., & Caban‐Holt, A. (2016) · IEEE Consumer Electronics Magazine · doi:10.1109/mce.2016.2590178 · Cited by 226 · see citing works
Schuurmans, A. A. T., de Looff, P., Nijhof, K. S., Rosada, C., Scholte, R. H. J., Popma, A., & Otten, R. (2020) · Journal of Medical Systems · doi:10.1007/s10916-020-01648-w · Cited by 210 · see citing works
Milstein, N., & Gordon, I. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.00148 · Cited by 180 · see citing works
Automated Epileptic Seizure Detection Based on Wearable ECG and PPG in a Hospital Environment
Vandecasteele, K., De Cooman, T., Gu, Y., Cleeren, E., Claes, K., Paesschen, W., Huffel, S., & Hunyadi, B. (2017) · Sensors · doi:10.3390/s17102338 · Cited by 174 · see citing works
Thomas, S. S., Nathan, V., Zong, C., Soundarapandian, K., Shi, X., & Jafari, R. (2015) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2015.2458779 · Cited by 140 · see citing works
A comparison of wearable and stationary sensors for stress detection
Ollander, S., Godin, C., Campagne, A., & Charbonnier, S. (2016) · Conference proceedings/Conference proceedings - IEEE International Conference on Systems, Man, and Cybernetics · doi:10.1109/smc.2016.7844917 · Cited by 136 · see citing works
Self-citationField based reliability and validity of the bioharness™ multivariable monitoring device.
Johnstone, J., Ford, P. A., Hughes, G., Watson, T., Mitchell, A., & Garrett, A. T. (2012) · Europe PMC (PubMed Central) · Cited by 85 · see citing works
Morelli, D., Rossi, A., Cairo, M., & Clifton, D. A. (2019) · Sensors · doi:10.3390/s19143163 · Cited by 76 · see citing works
Kemper, K. J., Hamilton, C. A., & Atkinson, M. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e318123fbcc · Cited by 74 · see citing works
Karlsson, M., Hörnsten, R., Rydberg, A., & Wiklund, U. (2012) · BioMedical Engineering OnLine · doi:10.1186/1475-925x-11-2 · Cited by 68 · see citing works
Quality Assessment of Ambulatory ECG Using Wavelet Entropy of the HRV Signal
Orphanidou, C., & Drobnjak, I. (2016) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2016.2615316 · Cited by 68 · see citing works
Matlab Implementation of Pan Tompkins ECG QRS detector.
Sedghamiz, H. (2014) · doi:10.13140/rg.2.2.14202.59841 · Cited by 62 · see citing works
Psychophysiological processes of mental effort investment.
Fairclough, S. H., & Mulder, L. J. M. (2011) · American Psychological Association eBooks · doi:10.1037/13090-003 · Cited by 56 · see citing works
Papini, G. B., Fonseca, P. M., Aubert, X. L., Overeem, S., Bergmans, J. W. M., & Vullings, R. (2017) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2017.8036776 · Cited by 36 · see citing works
A single channel ECG quality metric
Behar, J. A., Oster, J., Li, Q., & Clifford, G. D. (2012) · Computing in cardiology · Cited by 28 · see citing works
Sweeney, K. T., Kearney, D., Ward, T. E., Coyle, S. M., & Diamond, D. (2013) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2013.6609666 · Cited by 20 · see citing works
Assessment of different methods to estimate electrocardiogram signal quality
del Río, B. A. S., Lopetegi, T., & Romero, I. (2011) · Computing in cardiology · Cited by 20 · see citing works
Periyasamy, V., Pramanik, M., & Ghosh, P. (2017) · Journal of the Indian Institute of Science · doi:10.1007/s41745-017-0037-1 · Cited by 17 · see citing works
Rossi, A., Pedreschi, D., Clifton, D. A., & Morelli, D. (2020) · Sensors · doi:10.3390/s20247122 · Cited by 17 · see citing works
Field based reliability and validity of the Bioharness (TM) multivariable monitoring device
Johnstone, J. A., Ford, P. A., Hughes, G., Watson, T., Mitchell, A. C. S., & Garrett, A. T. (2012) · University of Hertfordshire Research Archive (University of Hertfordshire) · Cited by 13 · see citing works
FIELD BASED RELIABILITY AND VALIDITY OF THE BIOHARNESSTM MULTIVARIABLE MONITORING DEVICE
Garrett, A. T., Mitchell, A., Watson, T., Hughes, G., Ford, P. A., & Johnstone, J. (2012) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 12 · see citing works
Ambulant ECG Recording with Wet and Dry Electrodes: A Direct Comparison of two Systems
Fuhrhop, S., Lamparth, S., Kirst, M., Wagner, G., & Ottenbacher, J. (2009) · World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany · doi:10.1007/978-3-642-03904-1_85 · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Data quality evaluation in wearable monitoring
Böttcher, S., Vieluf, S., Bruno, E., Joseph, B., Epitashvili, N., Biondi, A., Zabler, N., Glasstetter, M., Dümpelmann, M., Van Laerhoven, K., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-25949-x · Cited by 91 · see citing works
A Survey of Photoplethysmography and Imaging Photoplethysmography Quality Assessment Methods
Desquins, T., Bousefsaf, F., Pruski, A., & Maaoui, C. (2022) · Applied Sciences · doi:10.3390/app12199582 · Cited by 33 · see citing works
Recent Advances in Vehicle Driver Health Monitoring Systems
Melders, L., Šmigins, R., & Birkavs, A. (2025) · Sensors · doi:10.3390/s25061812 · Cited by 23 · see citing works
Machado, A., Ferreira, D. F., Ferreira, S., Almeida‐Antunes, N., Carvalho, P. J., Melo, P. I. D. A., Rocha, N., & Rodrigues, M. A. (2025) · Sensors · doi:10.3390/s25196049 · Cited by 16 · see citing works
Sreeharsha, A., McHale, S., Nnamoko, N., & Pereira, E. (2024) · Electronics · doi:10.3390/electronics13244960 · Cited by 15 · see citing works
A PPG Signal Dataset Collected in Semi-Naturalistic Settings Using Galaxy Watch
Park, S., Zheng, D., & Lee, U. (2025) · Scientific Data · doi:10.1038/s41597-025-05152-z · Cited by 12 · see citing works
Vila, G. (2021) · theses.fr (ABES) · doi:10.70675/392ed3ffzc0a4z4036zb11ez0bb8f2b16351
Self-citationOlszewski, B., Uryga, A., Mataczyński, C., & Kasprowicz, M. (2026) · Physiological Measurement · doi:10.1088/1361-6579/ae95ae
- Authors
- Vila, G., Godin, C., Charbonnier, S., & Campagne, A.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Corresponding author
- Vila, Gaël
- Godin, Christelle
- Venue
- Sensors
- Publisher
- MDPI AG
- Published
- 2021-08-09
- Volume
- 21
- Issue
- 16
- Pages
- 5357
- ISSN
- 1424-8220 (ISSN-L)
- PMC
- PMC8400129
- OpenAlex
- W3175050776
- Cited by
- 8
- References
- 41
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2022: 2 · 2021: 1
- FWCI
- 0.30
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Sensors (publishedVersion, cc-by)
- Preprints.org (acceptedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › ECG Monitoring and Analysis
- Keywords
- heart rate variability, photoplethysmography, motion artifacts, data loss, quality index, Empatica E4, outlier removal
- MeSH terms
- Electrocardiography, Heart Rate, Monitoring, Physiologic, Signal Processing, Computer-Assisted, Artifacts, Photoplethysmography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review