Interference resolution in major depression
Open accessAbstract
In two experiments, we investigated individual differences in the ability to resolve interference in participants diagnosed with major depressive disorder (MDD). Participants were administered the "Ignore/Suppress" task, a short-term memory task composed of two steps. In Step 1 ("ignore"), participants were instructed to memorize a set of stimuli while ignoring simultaneously presented irrelevant material. In Step 2 ("suppress"), participants were instructed to forget a subset of the previously memorized material. The ability to resolve interference was indexed by response latencies on two recognition tasks in which participants decided whether a probe was a member of the target set. In Step 1, we compared response latencies to probes from the to-be-ignored list with response latencies to nonrecently presented items. In Step 2, we compared response latencies to probes from the to-be-suppressed list with response latencies to nonrecently presented items. The results indicate that, compared with control participants, depressed participants exhibited increased interference in the "suppress" but not in the "ignore" step of the task, when the stimuli were negative words. No group differences were obtained when we presented letters instead of emotional words. These findings indicate that depression is associated with difficulty in removing irrelevant negative material from short-term memory.
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Rumination is associated with decreases in the likelihood of new reward-based learning, weakens instrumental action, and reduces engagement of potentially rewarding social networks.
“rumination is associated with decreases in the likelihood of new reward-based learning, weakens instrumental action, and engagement of potentially rewarding social networks41–43 [contextual learning consequences].”
From AN OPEN TRIAL OF EMOTION REGULATION THERAPY FOR GENERALIZED ANXIETY DISORDER AND COOCCURRING DEPRESSION. (2015) · cites this paper as [42]
The Study 2 Discussion links rumination to difficulty removing irrelevant negative material from short-term memory. Searches for reward-based learning, instrumental action, and rewarding social engagement found no passage in our copy addressing those claimed consequences. (LLM, conf=0.73)
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- Authors
- Joormann, J., Nee, D. E., Berman, M. G., Jonides, J., & Gotlib, I. H.
- Affiliations
- University of Miami (US)
- University of Michigan (US)
- Stanford University (US)
- Corresponding author
- Joormann, J.
- Venue
- Cognitive, Affective, & Behavioral Neuroscience
- Published
- 2010-03-01
- Volume
- 10
- Issue
- 1
- Pages
- 21-33
- ISSN
- 1530-7026 (ISSN-L)
- 1531-135X
- PMC
- PMC2845922
- OpenAlex
- W2168900050
- Cited by
- 81
- References
- 62
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 6 · 2017: 4 · 2016: 8 · 2015: 5 · 2014: 8 · 2013: 8 · 2012: 10
- FWCI
- 5.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cognitive Affective & Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (MH-60655, MH59259, R01MH060655, R01MH059259)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- major depressive disorder, interference resolution, short-term memory, suppression, forgetting, emotional words, negative words, individual differences, memory interference, recognition memory
- MeSH terms
- Adolescent, Adult, Analysis of Variance, Attention, Decision Making, Major Depressive Disorder, Female, Humans, Individuality, Inhibition, Psychological, Male, Memory, Short-Term, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Surveys and Questionnaires, Reaction Time, Repression, Psychology, Young Adult
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