Type 2 diabetes mellitus and Alzheimer’s disease

Hearing loss and cognitive decline in older adults

Lin, F. R., Yaffe, K., Xia, J., Xue, Q.-L., Harris, T. B., Purchase-Helzner, E., Satterfield, S., Ayonayon, H. N., Ferrucci, L., Simonsick, E. M., et al. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.1868 · Cited by 4,017 · see citing works

Pathways towards and Away from Alzheimer’s Disease

Mattson, M. P. (2004) · Nature · doi:10.1038/nature02621 · Cited by 3,052 · see citing works

Risk of dementia in diabetes mellitus: a systematic review

Biessels, G. J., Staekenborg, S., Brunner, E., Brayne, C., & Scheltens, P. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(05)70284-2 · Cited by 2,187 · see citing works

Diabetes mellitus and the risk of dementia: The Rotterdam Study

Ott, A., Stolk, R. P., van Harskamp, F., Pols, H. A. P., Hofman, A., & Breteler, M. M. B. (1999) · Neurology · doi:10.1212/wnl.53.9.1937 · Cited by 2,175 · see citing works

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

Arvanitakis, Z., Wilson, R. S., Bienias, J. L., Evans, D. A., & Bennett, D. A. (2004) · Archives of Neurology · doi:10.1001/archneur.61.5.661 · Cited by 1,258 · see citing works

Alzheimer’s disease is type 3 diabetes—Evidence reviewed

de la Monte, S. M., & Wands, J. R. (2008) · Journal of Diabetes Science and Technology · doi:10.1177/193229680800200619 · Cited by 1,158 · see citing works

Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus

Whitmer, R. A. (2009) · JAMA · doi:10.1001/jama.2009.460 · Cited by 1,128 · see citing works

Increased Risk of Type 2 Diabetes in Alzheimer Disease

Janson, J., Laedtke, T., Parisi, J. E., O’Brien, P., Petersen, R. C., & Butler, P. C. (2004) · Diabetes · doi:10.2337/diabetes.53.2.474 · Cited by 950 · see citing works

Glucose Levels and Risk of Dementia

Crane, P. K., Walker, R., Hubbard, R. A., Li, G., Nathan, D. M., Zheng, H., Haneuse, S., Craft, S., Montine, T. J., Kahn, S. E., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1215740 · Cited by 929 · see citing works

Insulin and neurodegenerative disease: shared and specific mechanisms

Craft, S., & Stennis Watson, G. (2004) · The Lancet Neurology · doi:10.1016/s1474-4422(04)00681-7 · Cited by 830 · see citing works

Cognitive Dysfunction and Diabetes Mellitus

Kodl, C. T., & Seaquist, E. R. (2008) · Endocrine Reviews · doi:10.1210/er.2007-0034 · Cited by 823 · see citing works

Dementia and Alzheimer Disease Incidence: A Prospective Cohort Study

Kukull, W. A., Higdon, R., Bowen, J. D., McCormick, W. C., Teri, L., Schellenberg, G. D., van Belle, G., Jolley, L., & Larson, E. B. (2002) · Archives of Neurology · doi:10.1001/archneur.59.11.1737 · Cited by 806 · see citing works

Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy

Borroni, B., Malinverno, M., Gardoni, F., Alberici, A., Parnetti, L., Premi, E., Bonuccelli, U., Grassi, M., Perani, D., Calabresi, P., et al. (2008) · Neurology · doi:10.1212/01.wnl.0000335941.68602.39 · Cited by 677 · see citing works

Isolated bipallidal lesions caused by extrapontine myelinolysis.

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Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis

Qiu, W. Q., & Folstein, M. F. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.01.004 · Cited by 538 · see citing works

Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI

den Heijer, T., Vermeer, S. E., van Dijk, E. J., Prins, N. D., Koudstaal, P. J., Albert Hofman, D., & Breteler, M. M. B. (2003) · Diabetologia · doi:10.1007/s00125-003-1235-0 · Cited by 512 · see citing works

Relationship Between Baseline Glycemic Control and Cognitive Function in Individuals With Type 2 Diabetes and Other Cardiovascular Risk Factors

Cukierman‐Yaffe, T., Gerstein, H. C., Williamson, J. D., Lazar, R. M., Lovato, L., Miller, M. E., Coker, L. H., Murray, A. M., Sullivan, M. D., Marcovina, S. M., et al. (2009) · Diabetes Care · doi:10.2337/dc08-1153 · Cited by 452 · see citing works

Association Between Hypoglycemia and Dementia in a Biracial Cohort of Older Adults With Diabetes Mellitus

Yaffe, K. S. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.6176 · Cited by 434 · see citing works

Risk factors for progression of brain atrophy in aging

Enzinger, C., Fazekas, F., Matthews, P. M., Ropele, S., Schmidt, H., Smith, S. M., & Schmidt, R. (2005) · Neurology · doi:10.1212/01.wnl.0000161871.83614.bb · Cited by 397 · see citing works

(Pre)diabetes, brain aging, and cognition

Roriz‐Filho, J. S., Roriz, T. M. D. S., Rosset, I., Camozzato, A. L., dos Santos, A. C., Chaves, M. L. F., Moriguti, J. C., & Roriz‐Cruz, M. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.12.003 · Cited by 390 · see citing works

Implementing a screening and diagnosis program for dementia in primary care

Boustani, M., Callahan, C. M., Unverzagt, F. W., Austrom, M. G., Perkins, A. J., Fultz, B. A., Hui, S. L., & Hendrie, H. C. (2005) · Journal of General Internal Medicine · doi:10.1007/s11606-005-0103-7 · Cited by 374 · see citing works

Cognitive Dysfunction Is Associated With Poor Diabetes Control in Older Adults

Munshi, M. N., Grande, L. J., Hayes, M., Ayres, D., Suhl, E., Capelson, R., Lin, S. X., Milberg, W., & Weinger, K. (2006) · Diabetes Care · doi:10.2337/dc06-0506 · Cited by 371 · see citing works

Relationship Between Hyperglycemia and Cognitive Function in Older NIDDM Patients

Reaven, G. M., Thompson, L. W., Nahum, D., & Haskins, E. (1990) · Diabetes Care · doi:10.2337/diacare.13.1.16 · Cited by 334 · see citing works

The relationship between type 2 diabetes and cognitive dysfunction: longitudinal studies and their methodological limitations

Allen, K. V., Frier, B. M., & Strachan, M. W. J. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.02.054 · Cited by 319 · see citing works

Diabetes Mellitus and Risk of Developing Alzheimer Disease

Akomolafe, A., Beiser, A., Meigs, J. B., Au, R., Green, R. C., Farrer, L. A., Wolf, P. A., & Seshadri, S. S. (2006) · Archives of Neurology · doi:10.1001/archneur.63.11.1551 · Cited by 281 · see citing works

Hypoglycaemia and cognitive function

Warren, R. E., & Frier, B. M. (2004) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2004.00421.x · Cited by 219 · see citing works

Links between cognitive impairment in insulin resistance: An explanatory model

Convit, A. J. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.09.018 · Cited by 198 · see citing works

A look inside the diabetic brain: Contributors to diabetes-induced brain aging

Wrighten, S. A., Piroli, G. G., Grillo, C. A., & Reagan, L. P. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.10.013 · Cited by 195 · see citing works

Implementing a screening and diagnosis program for dementia in primary care.

Boustani, M. A., Callahan, C. M., Unverzagt, F. W., et al. (2005) · PubMed · doi:10.1111/j.1525-1497.2005.0126.x · Cited by 191 · see citing works

Higher normal fasting plasma glucose is associated with hippocampal atrophy

Cherbuin, N., Sachdev, P. S., & Anstey, K. J. (2012) · Neurology · doi:10.1212/wnl.0b013e31826846de · Cited by 170 · see citing works

Postprandial plasma glucose excursions and cognitive functioning in aged type 2 diabetics

Abbatecola, A. M., Rizzo, M. R., Barbieri, M., Grella, R., Arciello, A., Laieta, M. T., Acampora, R., Passariello, N., Cacciapuoti, F., & Paolisso, G. (2006) · Neurology · doi:10.1212/01.wnl.0000224760.22802.e8 · Cited by 169 · see citing works

Predictors of cognitive impairment and dementia in older people with diabetes

Bruce, D. G., Davis, W. A., Casey, G. P., STARKSTEIN, S. E., Clarnette, R., Foster, J. K., Almeida, O. P., & Davis, T. M. E. (2007) · Diabetologia · doi:10.1007/s00125-007-0894-7 · Cited by 148 · see citing works

Predictors of Cognitive Decline in Older Individuals With Diabetes

Bruce, D. G., Davis, W. A., Casey, G. P., STARKSTEIN, S. E., Clarnette, R., Almeida, O. P., & Davis, T. M. E. (2008) · Diabetes Care · doi:10.2337/dc08-0562 · Cited by 117 · see citing works

Oral magnesium supplementation improves vascular function in elderly diabetic patients.

Barbagallo, M., Dominguez, L. J., Galioto, A., Pineo, A., & Belvedere, M. (2010) · PubMed · doi:10.1684/mrh.2010.0214 · Cited by 108 · see citing works

People living with diabetes resident in nursing homes—assessing levels of disability and nursing needs

Gadsby, R., Barker, P., & Sinclair, A. J. (2011) · Diabetic Medicine · doi:10.1111/j.1464-5491.2011.03261.x · Cited by 52 · see citing works

Psychiatric Disorders Presenting in the Elderly With Type 2 Diabetes Mellitus

Alagiakrishnan, K., & Sclater, A. L. (2011) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31823038db · Cited by 49 · see citing works

Glucose control in the older patient: from intensive, to effective and safe

Dominguez, L. J., Paolisso, G., & Barbagallo, M. (2010) · Aging Clinical and Experimental Research · doi:10.1007/bf03337724 · Cited by 25 · see citing works

Blood-Brain Barrier: From Physiology to Disease and Back

Sweeney, M. D., Zhao, Z., Montagne, A., Nelson, A. R., & Zlokovic, B. V. (2019) · Physiological Reviews · doi:10.1152/physrev.00050.2017 · Cited by 2,294 · see citing works

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Thaiss, C. A., Levy, M., Grosheva, I., Zheng, D., Soffer, E., Blacher, E., Braverman, S., Tengeler, A. C., Barak, O., Elazar, M., et al. (2018) · Science · doi:10.1126/science.aar3318 · Cited by 942 · see citing works

Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

Nelson, A. R., Sweeney, M. D., Sagare, A. P., & Zlokovic, B. V. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.12.016 · Cited by 559 · see citing works

The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

Yu, D., Richardson, N. E., Green, C. L., Spicer, A. B., Trautman, M. E., Flores, V., Jang, C., Kasza, I., Nikodémová, M., Wakai, M. H., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.03.025 · Cited by 388 · see citing works

An updated meta-analysis of cohort studies: Diabetes and risk of Alzheimer’s disease

Zhang, J., Chen, C., Hua, S., Liao, H., Wang, M., Xiong, Y., & Cao, F. (2017) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2016.10.024 · Cited by 376 · see citing works

Protective effects of Akkermansia muciniphila on cognitive deficits and amyloid pathology in a mouse model of Alzheimer's disease

Ou, Z., Deng, L., Lu, Z., Wu, F., Liu, W., Huang, D., & Peng, Y. (2020) · Nutrition & Diabetes · doi:10.1038/s41387-020-0115-8 · Cited by 328 · see citing works

Alzheimer's disease and type 2 diabetes: a critical assessment of the shared pathological traits

Chatterjee, S., & Mudher, A. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00383 · Cited by 270 · see citing works

Dynamics of diabetes and obesity: Epidemiological perspective

Boles, A. N., Kandimalla, R. J. L., & Reddy, P. H. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.01.016 · Cited by 266 · see citing works

Nutrition and cognitive health: A life course approach

Puri, S., Shaheen, M., & Grover, B. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1023907 · Cited by 246 · see citing works

Future directions in Alzheimer's disease from risk factors to prevention

Imtiaz, B., Tolppanen, A., Kivipelto, M., & Soininen, H. S. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.01.003 · Cited by 229 · see citing works

A review on advances of treatment modalities for Alzheimer's disease

Thoe, E. S., Fauzi, A., Tang, Y.-Q., Chamyuang, S., & Chia, A. Y. Y. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119129 · Cited by 224 · see citing works

The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer’s Disease

Liu, Z., Li, T., Li, P., Wei, N., Zhao, Z., Liang, H., Ji, X., Chen, W., Xue, M., & Wei, J. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/352723 · Cited by 208 · see citing works

Heterogeneity in Alzheimer’s Disease Diagnosis and Progression Rates: Implications for Therapeutic Trials

Duara, R., & Barker, W. (2022) · Neurotherapeutics · doi:10.1007/s13311-022-01185-z · Cited by 187 · see citing works

Mechanisms of Insulin Resistance at the Crossroad of Obesity with Associated Metabolic Abnormalities and Cognitive Dysfunction

Barber, T. M., Kyrou, I., Randeva, H. S., & Weickert, M. O. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020546 · Cited by 178 · see citing works

Genetic correlations between Alzheimer’s disease and gut microbiome genera

Cammann, D., Lu, Y., Cummings, M. J., Zhang, M. L., Cue, J. M., Do, J., Ebersole, J. L., Chen, X., Oh, E. C. T., Cummings, J. L., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-31730-5 · Cited by 176 · see citing works

Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link

Takechi, R., Lam, V., Brook, E., Giles, C., Fimognari, N., Mooranian, A., Al‐Salami, H., Coulson, S., Nesbit, M., & Mamo, J. C. L. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00399 · Cited by 169 · see citing works

Effect of weight loss, exercise, or both on cognition and quality of life in obese older adults

Napoli, N., Shah, K., Waters, D. L., Sinacore, D. R., Qualls, C., & Villareal, D. T. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.082883 · Cited by 165 · see citing works

Insulin resistance and cognitive dysfunction

Ma, L., Wang, J., & Li, Y. (2015) · Clinica Chimica Acta · doi:10.1016/j.cca.2015.01.027 · Cited by 145 · see citing works

Link between Diabetes and Alzheimer’s Disease Due to the Shared Amyloid Aggregation and Deposition Involving Both Neurodegenerative Changes and Neurovascular Damages

Stanciu, G. D., Bild, V., Ababei, D. C., Rusu, R.-N., Cobzaru, A., Păduraru, L., & Bulea, D. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061713 · Cited by 126 · see citing works

Prevalence of type 2 diabetes mellitus, impaired fasting glucose, general obesity, and abdominal obesity in patients with bipolar disorder: A systematic review and meta-analysis

Liu, Y. K., Ling, S., Lui, L. M. W., Ceban, F., Vinberg, M., Kessing, L. V., Ho, R., Rhee, T. G., Gill, H., Cao, B., et al. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.12.110 · Cited by 105 · see citing works

An overview of the relationship between inflammation and cognitive function in humans, molecular pathways and the impact of nutraceuticals

Mekhora, C., Lamport, D. J., & Spencer, J. P. E. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105900 · Cited by 103 · see citing works

Akkermansia muciniphila in neuropsychiatric disorders: friend or foe?

Lei, W., Cheng, Y., Gao, J., Liu, X., Shao, L., Kong, Q., Zheng, N., Ling, Z., & Hu, W. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1224155 · Cited by 101 · see citing works

EEG spectral power abnormalities and their relationship with cognitive dysfunction in patients with Alzheimer's disease and type 2 diabetes

Benwell, C., Davila-Pérez, P., Fried, P. J., Jones, R. N., Travison, T. G., Santarnecchi, E., Pascual‐Leone, Á., & Shafi, M. M. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.10.004 · Cited by 100 · see citing works

Diabetes, Dementia and Hypoglycemia

Meneilly, G. S., & Tessier, D. (2016) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2015.09.006 · Cited by 98 · see citing works

Insulin resistance, an unmasked culprit in depressive disorders: Promises for interventions

Watson, K. T., Nasca, C., Aasly, L., McEwen, B. S., & Rasgon, N. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.11.038 · Cited by 95 · see citing works

Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases

Soares, L. C., Al‐Dalahmah, O., Hillis, J. M., Young, C. C., Asbed, I., Sakaguchi, M., O’Neill, E. E., & Szele, F. G. (2021) · Cells · doi:10.3390/cells10113047 · Cited by 94 · see citing works

Current Progress on Peroxisome Proliferator-activated Receptor Gamma Agonist as an Emerging Therapeutic Approach for the Treatment of Alzheimer's Disease: An Update

Khan, M. A., Alam, Q., Haque, A., Ashafaq, M., Khan, M. J., Ashraf, G. M., & Ahmad, M. (2018) · Current Neuropharmacology · doi:10.2174/1570159x16666180828100002 · Cited by 90 · see citing works

Type 2 Diabetes Mellitus Increases the Risk of Late-Onset Alzheimer’s Disease: Ultrastructural Remodeling of the Neurovascular Unit and Diabetic Gliopathy

Hayden, M. R. (2019) · Brain Sciences · doi:10.3390/brainsci9100262 · Cited by 90 · see citing works

Association between hypoglycemia and dementia in patients with type 2 diabetes

Sheen, Y., & Sheu, W. H. (2016) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2016.04.004 · Cited by 90 · see citing works

Interventions for age-related diseases: Shifting the paradigm

Figueira, I., Fernandes, A. M. A., Mladenović, A., Lopez-Contreras, A. J., Henriques, C. M., Selman, C., Ferreiro, E. B., Gonos, E. S., Trejo, J. L., Misra, J., et al. (2016) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2016.09.009 · Cited by 87 · see citing works

Shared genetic etiology underlying Alzheimer’s disease and type 2 diabetes

Hao, K., Di Narzo, A. F., Ho, L., Luo, W., Li, S., Chen, R., Li, T., Dubner, L., & Pasinetti, G. M. (2015) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2015.06.006 · Cited by 84 · see citing works

Semaglutide Attenuates Anxious and Depressive-Like Behaviors and Reverses the Cognitive Impairment in a Type 2 Diabetes Mellitus Mouse Model Via the Microbiota-Gut-Brain Axis

de Paiva, I. H. R., da Silva, R. S., Mendonça, I. P., Maciel, L. M., de Souza, J. R. B., & Peixoto, C. A. (2024) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-024-10142-w · Cited by 81 · see citing works

Insulin Treatment Prevents Neuroinflammation and Neuronal Injury with Restored Neurobehavioral Function in Models of HIV/AIDS Neurodegeneration

Mamik, M. K., Asahchop, E. L., Chan, W. F., Zhu, Y., Branton, W. G., McKenzie, B., Cohen, É. A., & Power, C. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1287-16.2016 · Cited by 81 · see citing works

Insulin resistance-induced hyperglycemia decreased the activation of Akt/CREB in hippocampus neurons: Molecular evidence for mechanism of diabetes-induced cognitive dysfunction

Xiang, Q., Zhang, J., Li, C., Wang, Y., Zeng, M.-J., Cai, Z.-X., Tian, R.-B., Jia, W. P., & Li, X. (2015) · Neuropeptides · doi:10.1016/j.npep.2015.08.009 · Cited by 80 · see citing works

Long-term use of metformin and Alzheimer’s disease: beneficial or detrimental effects

Al-Kuraishy, H. M., Al-Gareeb, A. I., Saad, ‏. M., & Batiha, G. E. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01163-7 · Cited by 78 · see citing works

Vascular pathology: Cause or effect in Alzheimer disease?

Rius‐Pérez, S., Tormos, A. M., Pérez, S., & Taléns‐Visconti, R. (2017) · Neurología (English Edition) · doi:10.1016/j.nrleng.2015.07.008 · Cited by 75 · see citing works

Associations Between Diabetes Mellitus and Neurodegenerative Diseases

Szablewski, L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26020542 · Cited by 74 · see citing works

Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses

Yashin, A. I., Fang, F., Kovtun, M., Wu, D., Duan, M., Arbeev, K. G., Akushevich, I. V., Kulminski, A. M., Culminskaya, I. V., Zhbannikov, I. Y., et al. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.10.020 · Cited by 72 · see citing works

Defining the Role of Isoeugenol from Ocimum tenuiflorum against Diabetes Mellitus-Linked Alzheimer’s Disease through Network Pharmacology and Computational Methods

Martiz, R. M., Patil, S. M., Abdulaziz, M., Babalghith, A. O., Al-Areefi, M. A., Al‐Ghorbani, M., Kumar, J. M., Prasad, A., Nagalingaswamy, N. P. M., & Ramu, R. (2022) · Molecules · doi:10.3390/molecules27082398 · Cited by 71 · see citing works

A Comprehensive Review of Neuronal Changes in Diabetics

Luna, R., Manjunatha, R. T., Bollu, B., Jhaveri, S., Avanthika, C., Reddy, N., Saha, T., & Gandhi, F. R. (2021) · Cureus · doi:10.7759/cureus.19142 · Cited by 70 · see citing works

Patología vascular: ¿causa o efecto en la enfermedad de Alzheimer?

Rius‐Pérez, S., Tormos, A. M., Pérez, S., & Taléns‐Visconti, R. (2015) · Neurología · doi:10.1016/j.nrl.2015.07.010 · Cited by 70 · see citing works

Tirzepatide prevents neurodegeneration through multiple molecular pathways

Fontanella, R. A., Ghosh, P., Pesapane, A., Taktaz, F., Puocci, A., Franzese, M., Feliciano, M. F., Tortorella, G., Scisciola, L., Sommella, E., et al. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-04927-z · Cited by 67 · see citing works

Hyperglycemia Increases the Production of Amyloid Beta‐Peptide Leading to Decreased Endothelial Tight Junction

Chao, A., Lee, T.-Y., Juo, S. H., & Yang, D. (2016) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12503 · Cited by 67 · see citing works

Aging, Diabetes, Obesity, and Cognitive Decline: A Population‐Based Study

Ganguli, M., Beer, J. C., Zmuda, J. M., Ryan, C. M., Sullivan, K., Chang, C. H., & Rao, R. H. (2020) · Journal of the American Geriatrics Society · doi:10.1111/jgs.16321 · Cited by 66 · see citing works

Insulin signaling: An opportunistic target to minify the risk of Alzheimer’s disease

Pardeshi, R., Bolshette, N. B., Gadhave, K., Ahire, A., Ahmed, S., Cassano, T., Gupta, V. B., & Lahkar, M. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.05.004 · Cited by 65 · see citing works

Insulin mediated novel therapies for the treatment of Alzheimer's disease

Dubey, S. K., Lakshmi, K. K., Krishna, K. V., Agrawal, M., Singhvi, G., Saha, R. N., Saraf, S., Saraf, S., Shukla, R., & Alexander, A. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.117540 · Cited by 60 · see citing works

Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model

Chen, W., Huang, Q., Lazdon, E., Gomes, A., Wong, M., Stephens, E. R., Royal, T. G., Frenkel, D., Cai, W., & Kahn, C. R. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2220684120 · Cited by 60 · see citing works

Metabolic syndrome as a risk factor for Alzheimer's disease: Is Aβ a crucial factor in both pathologies?

Campos-Peña, V., Toral-Rios, D., Becerril-Pérez, F., Sánchez-Torres, C., Delgado-Namorado, Y., Torres-Ossorio, E., Franco-Bocanegra, D., & Carvajal, K. (2017) · Antioxidants & Redox Signaling · doi:10.1089/ars.2016.6768 · Cited by 58 · see citing works

Hypoglycemia is associated with dementia in elderly patients with type 2 diabetes mellitus: An analysis based on the Korea National Diabetes Program Cohort

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The Action of Polyphenols in Diabetes Mellitus and Alzheimer's Disease: A Common Agent for Overlapping Pathologies

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